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hybrid rice technology for food security in the world

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作物研究 2004年第4期18卷 185-186页

作者： YUAN Long-ping(china national hybrid rice r & d center,changsha,Hunan,410125,china) china national hybrid rice r & d center ChangshaHunan410125China

The current world population is over 6 billion and will reach 8 billion in 2030. Meanwhile, the annual loss of land to other use is 10 to 35 million ha, with half of this lost land coming from *** such severe situation of population growth pressure plus cropland reduction, it is obvious that the only way to solve food shortage problem is to greatly enhance the yield level of food crops per unit land area through advance of science and technology.

关键词： hybrid rice technology for food security in the world line

A draft sequence of the rice (Oryza sativa ssp. indica) genome

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Chinese Science Bulletin 2001年第23期46卷 1937-1942页

作者： YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,dENG Yajun, dAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, dONG Wei,rEN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, dONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, china Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, china Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, china national hybrid rice r & d center, changsha 410125, china Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, china College of Life Sciences, Peking University, Beijing 100871, china Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, china digital china Ltd., Beijing 100080, china Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, china Medical College, Xi’an Jiaotong University, Xi’an 710061, chinaThese authors contributed equally to this work.Corresponding author.Corresponden Beijing Genomics Institute/center of Genomics & Bioinformatics Chinese Academy of Sciences Beijing China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province Hangzhou China College of Life Sciences Peking University Beijing China Medical College Xi’an Jiaotong University Xi’an China Institute of Genetics Chinese Academy of Sciences Beijing China Laboratory of Bioinformatics Institute of Biophysics Chinese Academy of Sciences Beijing China national hybrid rice r & d center Changsha China Institute of Theoretical Physics Chinese Academy of Sciences Beijing China digital china Ltd. Beijing China Institute of Computing Technology Chinese Academy of Sciences Beijing China

The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a "whole genome shotgun" approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in china and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLEr, a custom-designed software package

关键词： rice genome draft sequences.

real-World Treatment Adherence to Smoking Cessation Medications and Association with Treatment Outcome—27 centers,china,2017–2022

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china CdC weekly 2024年第22期6卷 522-529,I0001-I0003页

作者： Anqi Cheng Zhao Liu Xinmei Zhou Zheng Su dan Xiao Chen Wang the china national Tobacco Cessation Cohort Study(CNTCCS)Study Group department of Tobacco Control and Prevention of respiratory disease Center of Respiratory MedicineChina-Japan Friendship Hospital/WHO Collaborating Center for Tobacco Cessation and Respiratory Diseases Prevention/National Center for Respiratory Medicine/National Clinical Research Center for Respiratory Diseases/Institute of Respiratory MedicineChinese Academy of Medical SciencesBeijingChina department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina-Japan Friendship Hospital/WHO Collaborating Center for Tobacco Cessation and Respiratory Diseases Prevention/China National Center for Respiratory Medicine/China National Clinical Research Center for Respiratory DiseasesBeijingChina Chinese Academy of Medical Sciences and Peking Union Medical College BeijingChina 不详

What is already known about this topic?Medication non-adherence significantly impedes smoking cessation *** effective smoking cessation medications are accessible in china,realworld adherence and its correlation with treatment outcomes remain largely *** is added by this report?From december 2017 to January 2022,1,120 participants were recruited from 27 centers in all seven geographical regions of *** revealed that only 38.2%of smokers adhered to the prescribed 12-week smoking cessation treatment and those with a higher education level were more likely to be *** addition,smokers with good adherence were more likely to successfully quit *** are the implications for public health practice?The data obtained could enhance our understanding of smoking cessation practices in *** adherence is a crucial strategy to enhance the effectiveness of smoking cessation treatments and management provided to smokers.

关键词： china smoke likely

hybrid rice research and development in china and Its New Progress

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Hunan Agricultural Science ＆ Technology Newsletter 2000年第3期1卷 5-12页

作者： Luo runliang (china national hybrid rice r&d center, changsha 410125) china national hybrid rice r&d center Changsha 410125

hybrid rice's history and its development up to date are described in the paper. Compared with the conventional rice, hybrid rice can increase grain yield by about 20%. hybrid rice breeding in china has been advancing along the three-line method, to two-line method, to super high-yielding rice application strategically and its success in higher degree will be seen by the utilization of distant heterosis cooperated with biotechnology.

关键词： hybrid rice Three-line method Two-line method Super rice distant heterosis Biotechnology

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Super hybrid rice

Hunan Agricultural Science ＆ Technology Newsletter 2000年第1期1卷 8-12页

作者： Yuan Longpingchina national hybrid rice r&d center, changsha 410125, china national hybrid rice r&d center Changsha 410125

Plant breeders realize that, up to now, there are only two effective ways to in-crease the yield potential of crops through breeding, i.e. morphologic improvement and heterosis utilization. However, the potential is very limited by using morphologic improvement alone, and heterosis breeding will produce undesirable results if it does not combine with morphologic improvement. Any other breeding approaches and methods including high technology like molecular breeding must be incorporated in-to good morphologic characters and strong heterosis, otherwise there will be no actu-al contributions to yield increase. On the other hand , the further development of plant breeding for high target must rely on the progress of biotechnology.

关键词：水稻超级杂交稻产量株型栽培技术亚种间杂交优势野生稻资源

Association between ICU quality and in-hospital mortality of V-V ECMO-supported patients—the ECMO quality improvement action(EQIA)study:a national cohort study in china from 2017 to 2019

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Frontiers of Medicine 2024年第2期18卷 315-326页

作者： Wei Cheng Jieqing Chen Xudong Ma Jialu Sun Sifa Gao Ye Wang Longxiang Su Lu Wang Wei du Huaiwu He Yujie Chen Zunzhu Li Qi Li Jianhua Sun Hongbo Luo Jinbang Liu Guangliang Shan Bing du Yanhong Guo dawei Liu Chang Yin Xiang Zhou on behalf of the china national Critical Care Quality Control center-the ECMO quality improvement action(EQIA)study department of Critical Care Medicine State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing100730China Information center department/department of Information Management State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalPeking Union Medical College&Chinese Academy of Medical SciencesBeijing100730China department of Medical Administration National Health Commission of the People’s Republic of ChinaBeijing100044China School of Population Medicine and Public Health Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing100730China department of Epidemiology and Biostatistics Institute of Basic Medicine SciencesChinese Academy of Medical Sciences(CAMS)&School of Basic MedicinePeking Union Medical CollegeBeijing100730China national Institute of Hospital Administration National Health Commission of the People’s Republic of ChinaBeijing100044China 不详

This cohort study was performed to explore the influence of intensive care unit(ICU)quality on in-hospital mortality of veno-venous(V-V)extracorporeal membrane oxygenation(ECMO)-supported patients in *** study involved all V-V ECMO-supported patients in 318 of 1700 tertiary hospitals from 2017 to 2019,using data from the national Clinical Improvement System and china national Critical Care Quality Control *** quality was assessed by quality control indicators and capacity *** the 2563 V-V ECMO-supported patients in 318 hospitals,a significant correlation was found between ECMO-related complications and *** reintubation rate within 48 hours after extubation and the total ICU mortality rate were independent risk factors for higher in-hospital mortality of V-V ECMO-supported patients(cutoff:1.5%and 7.0%;95%confidence interval:1.05–1.48 and 1.04–1.45;odds ratios:1.25 and 1.23;P=0.012 and P=0.015,respectively).Meanwhile,the V-V ECMO center volume was a protective factor(cutoff of≥50 cases within the 3-year study period;95%confidence interval:0.57–0.83,odds ratio:0.69,P=0.0001).The subgroup analysis of 864 patients in 11 high-volume centers further strengthened these ***,ICU quality may play an important role in improving the prognosis of V-V ECMO-supported patients.

关键词： veno-venous extracorporeal membrane oxygenation in-hospital mortality high-volume centers quality control intensive care unit capacity parameters

Use of Chinese hybrid rice with modified SrI in Guinea

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Hunan Agricultural Science ＆ Technology Newsletter 2003年第3期4卷 13-15页

作者： Peng Jiming, and Wang Xuehua china national hybrid rice research and development center, changsha 410125, china china Natioaal hybrid rice research and development center Changsha 410125 China

Guinea is one of the nations in West Africa where rice is an important andmain staple food for the people. Its rice average yield is only 1.5 tons per hectare, however, muchlower than those in the rest of the world. With the increase of the population, the shortfall inrice production becomes more and more serious. Therefore, it is very important to increase the riceyield. We made the field experiments with the Chinese hybrid rice using modified SrI (system of riceintensification) practices in Guinea from January to May 2003. Compared with Guinea's presentcultivars, the result showed that the Chinese hybrid rice with modified SrI can obtained high yieldswith vast yield potential, and the highest yield was 9232 kg ha^(-1). On April 28, the riceexpertsand officials from Ministry of Agriculture and Animals of Guinea and its rice research Institute andSeed Company, the large-size rice farms, Office of FAO in Guinea, china Agri-business Farm (Group)Company, china national hybrid rice r&d Centre and Chinese Embassy in Guinea assessed theexperiments conducted in Koba County, Guinea. They gave high praise to these efforts and thought ithas bright future in Guinea.

关键词：几内亚杂交水稻中国种质种质改良

2023 Chinese national clinical practice guideline on diagnosis and management of ulcerative colitis

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中华医学杂志(英文版) 2024年第14期137卷 1642-1646页

作者： Inflammatory Bowel disease Group, Chinese Society of Gastroenterology, Chinese Medical Association Inflammatory Bowel disease Quality Control center of china Inflammatory Bowel disease Group Chinese Society of Gastroenterology Chinese Medical Association Inflammatory Bowel disease Quality Control center of china

The role of Chinese expert consensus in standardization and improvement of the clinical diagnosis and treatment of inflammatory bowel disease (IBd) is self-evident. As clinical and basic research in china becomes standardized under a better understanding of IBd, more data on Chinese patients have become available to develop a consensus and guideline. This guideline, collaboratively developed by the IBd Group, Chinese Society of Gastroenterology, incorporates the latest international consensus statements, domestic research findings, and practical considerations, as an update based on the 2018 Chinese consensus on IBd management. The IBd guideline consists of two parts: ulcerative colitis (UC) and Crohn's disease, and this manuscript presented the UC part. The evidence used in this guideline was collected and analyzed by the standard of guideline, and the contents were organized as problem statements, for clarity. The formulation of this guideline aimed to reflect the latest progress in IBd, providing comprehensive and valuable guidance for the clinical management of IBd.

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Enhancing disease resistances of Super hybrid rice with four antifungal genes

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Science china(Life Sciences) 2007年第1期50卷 31-39页

作者： ZHU HuaChen1, XU XinPing1, XIAO GuoYing2,3, YUAN LongPing2 & LI BaoJian1 1 Biotechnology research center, Key Laboratory of Gene Engineering of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, china 2 china national hybrid rice r&d center, Hunan hybrid rice research center, changsha 410125, china 3 Institute of Subtropical Agriculture, the Chinese Academy of Sciences, changsha 410125, china Biotechnology research center Key Laboratory of Gene Engineering of Ministry of Education Sun Yat-sen University Guangzhou 510275 China china national hybrid rice r&d center Hunan Hybrid Rice Research Center Changsha 410125 China Institute of Subtropical Agriculture the Chinese Academy of Sciences Changsha 410125 China china national hybrid rice r&d center Hunan Hybrid Rice Research Center Changsha 410125 China

A plant expression vector harboring four antifungal genes was delivered into the embryogenic calli of ‘9311’, an indica restorer line of Super hybrid rice, via modified biolistic particle bombardment. Southern blot analysis indicated that in the regenerated hygromycin-resistant plants, all the four anti-fungal genes, including rCH10, rAC22, β-Glu and B-rIP, were integrated into the genome of ‘9311’, co-transmitted altogether with the marker gene hpt in a Mendelian pattern. Some transgenic r1 and r2 progenies, with all transgenes displaying a normal expression level in the Northern blot analysis, showed high resistance to Magnaporthe grisea when tested in the typical blast nurseries located in Yanxi and Sanya respectively. Furthermore, transgenic F1 plants, resulting from a cross of r2 homo-zygous lines with high resistance to rice blast with the non-transgenic male sterile line Peiai 64S, showed not only high resistance to M. grisea but also enhanced resistance to rice false smut (a disease caused by Ustilaginoidea virens) and rice kernel smut (another disease caused by Tilletia barclayana).

关键词： Super hybrid rice multi-gene transformation rice blast rice false smut rice kernel smut anti-fungi disease resistance