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Impact of delay from transperineal biopsy to radical prostatectomy upon objective measures of cancer control

Asian Journal of Urology 2022年第2期9卷 170-176页

作者： Liang G.Qu Gregory Jack Marlon Perera Melanie Evans Sue Evans Damien Bolton nathan papa Department of Urology Olivia Newton John Cancer CentreAustin HealthHeidelberg VICAustralia Department of Surgery University of MelbourneMelbourne VICAustralia Department of Epidemiology and Preventive Medicine Monash UniversityMelbourne VICAustralia

Objective:Treatment delays in prostate cancer have been characterised,although not explicitly in men undergoing transperineal prostate *** aimed to determine if delays to radical prostatectomy correlate with adverse outcomes using a contemporary population-based cohort of men diagnosed by transperineal ***:This study analysed men with prostate cancer of the International Society for Urological Pathology grade group≥2,diagnosed by transperineal prostate biopsies who underwent prostatectomy,using the prospectively data from 1 January 2014 to 30 June 2018 Prostate Cancer Outcomes *** were analysed according to stratified demographic and disease *** intervals from biopsy(28,60,90,120,and 270 days)were compared using odds ratios and regression analyses for proportion of upgrading,early biochemical recurrence,pT3 disease at prostatectomy,and positive surgical ***:In total,2008 men were *** were 306(16.7%)men with upgrading,151(8.4%)with biochemical recurrence,1068(54.1%)with pT3 disease,and 464(23.1%)with positive surgical margins(percentages excluded patients with missing data).All adverse outcomes studied were significantly associated with higher prostate-specific antigen and grade at *** of 120-270 days did not adversely alter the incidence of Gleason upgrading,pT3,or ***(most frequent 60-89 days,28%)were associated with positive surgical margins but not *** modelling demonstrated no increased likelihood of most adverse outcomes for up to 270 ***:Men with prostate cancer of grade group≥2 diagnosed through transperineal biopsy may wait up to 270 days for a prostatectomy without a greater likelihood of upgrading,pT3 disease,positive surgical margins,or biochemical recurrence.

关键词： Biopsy Disease progression Prostate cancer Recurrence Treatment delay

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An End to China’s Imbalances?

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China's Foreign Trade 2012年第5期 24-26页

作者： Ashvin Ahuja Nigel Chalk Malhar Nabar papa N’Diaye nathan Porter International Monetary Fund

As early as 2005,analysts and academics ecame concerned bout the prospects for,and sustainability of,growing current account imbalances in the world’s largest economies. In the United States, low savings rates and growing household consumption,fueled in part by what later turned out to be a bubble in the property market,sucked in imports

关键词：不平衡中国贸易伙伴可持续性家庭消费美国

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