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Occupational injuries and burn out among orthopedic oncology surgeons

World Journal of Orthopedics 2022年第12期13卷 1056-1063页

作者： Abdulrahman M Alaseem Robert E Turcotte nathalie ste-marie Mohammad M Alzahrani Saad M Alqahtani Krista A Goulding Department of Orthopedic Surgery College of MedicineKing Saud UniversityRiyadh 12372Saudi Arabia Department of Orthopedic Surgery McGill University Health CentreMontreal H4A3J1Canada Department of Orthopedic Surgery College of MedicineImam Abdulrahman Bin Faisal universityDammam 34212Saudi Arabia Department of Orthopaedic Surgery Mayo ClinicPhoenixArizona 85054USA

BACKGROUND Orthopedic oncology surgeons commonly engage in prolonged and complex surgical *** types of surgeries increase the risk of physical and psychological stressors,which may in turn make these physicians prone to workrelated occupational *** The aim of this study was to explore in orthopedic oncologists,the prevalence of work-related physical injuries and psychological *** A modified version of the physical discomfort survey was developed to assess occupational injuries among orthopedic oncology surgeon members of the Musculoskeletal Tumor Society,the Canadian Orthopedic Oncology Society and European Musculoskeletal Oncology *** survey was sent by email,and it explored musculoskeletal complaints,psychological disturbances,treatment required for these complaints and the requirement of time off *** A total of 67 surgeon responses were collected.A high number of orthopedic oncologists(84%)reported an occupational *** back pain(39%)was the most prevalent musculoskeletal condition,followed by lumbar disk herniation(16%),shoulder tendinitis(15%)and lateral epicondylitis(13%).Of the cohort,46%required surgery and 31%required time off work due to their ***-three respondents reported a psychological ***(27%),anxiety(20%)and insomnia(20%)were the most commonly *** required off work due to injury was associated with old age and years in *** Orthopedic oncology surgeons report a high prevalence of work-related *** back related injury and burnout were the most reported *** operative room ergonomics and prevention of stress related to the work environment should be areas to explore in upcoming research.

关键词： Orthopedic oncology Surgeons Occupational Musculoskeletal Injuries

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Testicular sperm extraction(TESE)outcomes in the context of malignant disease:a systematic review

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Asian Journal of Andrology 2022年第6期24卷 584-590页

作者： Ludmilla Ogouma Isabelle Berthaut Rachel Lévy Rahaf Haj Hamid marie Prades marie Audouin nathalie Sermondade Charlotte Dupont Fertility Center(Service de Biologie de la Reproduction CECOS) Tenon Hospital(AP-HPSorbonne-Universite)Paris F-75020France Sorbonne University Saint Antoine Research CenterInserm Us938Paris F-75012France Fertility Center Diaconesses HospitalParis F-75012France

Advances in the oncology field have led to improved survival ***,quality of life after remission is anticipated,which includes the possibility to conceive *** cancer treatments are potentially gonadotoxic,fertility preservation must be *** fertility preservation is mainly based on ejaculated sperm *** this is not possible,testicular sperm extraction(TESE)may be *** identify situations in which TESE has been beneficial,a systematic review was *** search was carried out on the PubMed,Scopus,Google Scholar,and CISMeF databases from 1 January 2000 to 19 March *** Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)recommendations were followed in selecting items of ***-four articles were included in the systematic review,including 15 articles on oncological testicular sperm extraction(oncoTESE),18 articles on postgonadotoxic treatment TESE and 1 article on both oncoTESE and postgonadotoxic treatment *** sperm freezing was possible for 42.9%to 57.7%of patients before gonadotoxic treatment and for 32.4%to 75.5%of patients after gonadotoxic treatment,depending on the type of malignant *** no formal conclusion could be drawn about the chances to obtain sperm in specific situations,our results suggest that TESE can be proposed before and after gonadotoxic *** treatment,TESE is more often proposed for men with testicular cancer presenting with azoospermia since TESE can be performed simultaneously with tumor removal or *** chemotherapy,TESE may be planned if the patient presents with persistent azoospermia.

关键词： cancer fertility preservation oncological testicular sperm extraction spermatozoa testicular sperm extraction

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Inflamed phenotype of splenic marginal zone B-cell lymphomas with expression of PD-L1 by intratumoral monocytes/macrophages and dendritic cells

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Cellular & Molecular Immunology 2019年第6期16卷 621-624页

作者： Christelle Vincent-Fabert Isabelle Soubeyran Valérie Velasco marie Parrens Robin Jeannet Emilie Lereclus nathalie Gachard Jean Feuillard nathalie Faumont CNRS-UMR 7276 INSERM U1262 CRIBL University of Limogesand Hematology Laboratory of Dupuytren Hospital University Center(CHU)of LimogesLimogesFrance Laboratory of Pathology Institut BergoniéBordeauxFrance Pathology Department Hospital University Center of BordeauxBordeauxFrance

Splenic marginal zone lymphoma(SMZL)is an incurable indolent small B-cell lymphoma that primarily involves the spleen and arises in elderly patients,who have a median age of 65 years old at diagnosis.1 Splenomegaly is... 详细信息

关键词： lymphoma spleen patients

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Froth flotation of scheelite – A review

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International Journal of Mining Science and Technology 2018年第3期28卷 373-384页

作者： nathalie Kupka Martin Rudolph Helmholtz Zentrum Dresden Rossendorf (HZDR) Helmholtz Institute Freiberg for Resource Technology (HIF)

Froth flotation of scheelite has regained new focus since the 2010s and research regarding floatability and reagents has made great progress over the years. The main objective was and remains the selective flotation of scheelite from other calcium-bearing minerals, in particular calcite, fluorite and apatite. Due to similar properties, most attempts have limited success or only specific application(linked to a type of ore or a location). This article aims at reviewing all general physical-chemical information on froth flotation of scheelite, including electrokinetic properties, influence of p H and already existing reagents as well as ones still under examination. It appears that chelating or mixed collectors and modified versions of sodium silicate and quebracho hold great promise for scheelite flotation, while the use of said depressants and/or promoters seems inevitable.

关键词： Scheelite Froth flotation Calcium-bearing minerals Selectivity challenges Promising reagents

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Millimeter wave band ultra wideband transmitter MMIC

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Journal of Semiconductors 2015年第9期36卷 125-130页

作者：金凌 nathalie Rolland SVA Communication Technology Co. Ltd Institut d'Electronique de Microélectronique et de NanotechnologieUSTLVilleneuve d'Ascq CedexFrance

This paper presents a new millimeter-wave （MMW） ultra wideband （UWB） transmitter MMIC which has been developed in an OMMIC 0.1 μm GaAs PHEMT foundry process （ft= 100 GHz） for 22-29 GHz vehicular radar systems. The transmitter is composed of an MMW negative resistance oscillator （NRO）, a power amplifier （PA）, and two UWB pulse generators （PGs）. In order to convert the UWB pulse signal to MMW frequency and reduce the total power consumption, the MMW NRO is driven by one of the UWB pulse generators and the power amplifier is triggered by another UWB pulse generator. The main advantages of this transmitter are： new design, simple architecture, high-precision distance measurements, infinite ON/OFF switch ratio, and low power consumption. The total power consumption of the transmitter MMIC is 218 mW with a peak output power of 5.5 dBm at 27 GHz.

关键词： millimeter-wave ultra wideband transmitter negative resistance oscillator MMIC GaAs pHEMT

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Thin films of binary amorphous Zn-Zr alloys developed by magnetron co-sputtering for the production of degradable coronary stents:A preliminary study

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Bioactive Materials 2018年第4期3卷 385-388页

作者： nathalie Annonay Fatiha Challali marie-Noelle Labour Valerie Bockelee A.Garcia-Sanchez Florent Tetard marie-Paule Besland Philippe Djemia Frederic Chaubet Laboratoire de Science des Materiaux et des Procedes UPR CNRS 3407Universite Paris 13Sorbonne-Paris-CiteInstitut Galilee99 av J.B.Clement93430VilletaneuseFrance Laboratory for Vascular Translational Science Inserm U1148Universite Paris 13Universite Paris-DiderotSorbonne-Paris-CiteInstitut Galilee99 av J.B.Clement93430VilletaneuseFrance Institut des Materiaux Jean Rouxel(IMN)UMR CNRS 6502 Universite de Nantes2rue de la HoussiniereB.P.3222944322Nantes Cedex 3France

*** Vascular stents are endo-prostheses that allow the restoration of blood flow in case of obstruction of a vessel.A stent usually consists of a corrosion-resistant metal such as Nitinol,316L steel or a CoCr alloy[1].Many studies have been undertaken for the production of polymer degradable stents[2,3]or metallic stents[4,5]and,among these,devices made of pure zinc or crystallized alloy based on zinc obtained by molding and extrusion are promising in terms of biodegradability,biocompatibility and mechanical properties[6],but also concerning the degradation rate of the stent which should to be effective until arterial remodeling and tissue healing are complete[5].The objective of this preliminary study is the comparison of the degradation in simulated biological medium and the endothelial cytotoxicity of amorphous and crystallized thin ZnZr films according to their composition and *** this work,the thin layers were deposited on silicon substrates by magnetron *** technology is already used to make metal stents[7,8].

关键词： alloy alloys corrosion

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Egg quality, fatty acid composition and immunoglobulin Y content in eggs from laying hens fed full fat camelina or flax seed

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Journal of Animal Science and Biotechnology 2016年第3期7卷 374-381页

作者： Gita Cherian nathalie Quezada Department of Animal and Rangeland Sciences Oregon State University

Background： The current study was conducted to evaluate egg quality and egg yolk fatty acids and immunoglobulin（Ig Y） content from laying hens fed full fat camelina or flax ***： A total of 75, 48-week-old Lohman brown hens were randomly allocated to 3 treatments, with 5replicates containing 5 laying hens each replicate. The hens were fed corn-soybean basal diet（Control）, or Control diet with 10 % of full fat camelina（Camelina） or flax seed（Flax） for a period of 16 wk. Hen production performance egg quality, egg yolk lipids, fatty acids and Ig Y were determined every 28 d during the experimental ***： Egg production was higher in hens fed Camelina and Flax than in Control hens（P 〈 0.05）. Egg weight and albumen weight was lowest in eggs from hens fed Camelina（P 〈 0.05）. Shell weight relative to egg weight（shell weight %）, and shell thickness was lowest in eggs from hens fed Flax（P 〈 0.05）. No difference was noted in Haugh unit, yolk：albumen ratio, and yolk weight. Significant increase in α-linolenic（18：3 n-3）, docosapentaenoic（22：5 n-3）and docoshexaenoic（22：6 n-3） acids were observed in egg yolk from hens fed Camelina and Flax. Total n-3 fatty acids constituted 1.19 % in Control eggs compared to 3.12 and 3.09 % in Camelina and Flax eggs, respectively（P 〈 0.05）. Eggs from hens fed Camelina and Flax had the higher Ig Y concentration than those hens fed Control diet when expressed on a mg/g of yolk basis（P 〈 0.05）. Although the egg weight was significantly lower in Camelina-fed hens, the total egg content of Ig Y was highest in eggs from hens fed Camelina（P 〈 0.05）.Conclusions： The egg n-3 fatty acid and Ig Y enhancing effect of dietary camelina seed warrants further attention into the potential of using camelina as a functional feed ingredient in poultry feeding.

关键词： Camelina seed Egg quality Flax seed Immunoglobulin Y n-3 fatty acids

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Early osmotic adjustment responses in drought-resistant and drought-sensitive oilseed rape

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Journal of Integrative Plant Biology 2014年第8期56卷 797-809页

作者： Sarah Hatzig L.Irina Zaharia Suzanne Abrams marie Hohmann Laurie Legoahec Alain Bouchereau nathalie Nesi Rod J.Snowdon Department of Plant Breeding IFZ Research Centre for Biosystems Land Use and Nutrition Justus Liebig University National Research Council of Canada Aquatic and Crop Resource Development Department of Chemistry University of Saskatchewan UMR 1349 INRA-AgroCampus Ouest-Université de Rennes 1 Joint Laboratory for Genetics Environment and Plant Protection (IGEPP) Bat.301 BP 35327 35653 Le Rheu Cedex France

The impact of osmotic stress on growth, physiolo- gy, and metabolism of winter oilseed rape （Brassica napus L.） was investigated by detailed analysis of biomass traits, hormone metabolites and osmolytes in two genetically unrelated drought-tolerant genotypes and two unrelated drought-sensitive genotypes. Seedlings were grown in vitro under controlled conditions and osmotic stress was simulated by applying a gradual treatment with polyethylene glycol （PEG 6ooo）, followed by hypo-osmotic treatment of variants used for metabolite determination. The results provide a basis for the identification of reliable selection criteria for drought resistance in oilseed rape. The in vitro cultivation system established during this study enabled effective discrimination of early osmotic stress responses between drought-resistant and -susceptible oilseed rape genotypes that also show large differences in relative seed yield under drought conditions in the field. Clear physiological and metabolic differences wereobserved between the drought-resistant and drought-sensitive genotypes, suggesting that osmotic adjustment is a key component of drought response in oilseed rape. Unexpected- ly, however, the drought-resistant genotypes did not show typical hormonal adjustment and osmolyte accumulation, suggesting that they possess alternative physiological mech- anisms enabling avoidance of stress symptoms.

关键词： Abscisic acid Brassica napus drought hormones metabolites

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Predictive-reactive Strategy for Flowshop Rescheduling Problem:Minimizing the Total Weighted Waiting Times and Instability

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Journal of Systems Science and Systems Engineering 2021年第3期30卷 253-275页

作者： Ayoub Tighazoui Christophe Sauvey nathalie Sauer Universitéde Lorraine LGIPMF-57000MetzFrance

Due to the fourth revolution experiencing,referred to as Industry 4.0,many production firms are devoted to integrating new technological tools to their manufacturing *** of them,is rescheduling the tasks on the machines responding to ***,for static scheduling,the efficiency criteria measure the performance of scheduling systems,in dynamic environments,the stability criteria are also used to assess the impact of jobs *** this paper,a new performance measure is investigated for a flowshop rescheduling *** one considers simultaneously the total weighted waiting time as the efficiency criterion,and the total weighted completion time deviation as the stability *** fusion could be a very helpful and significant measure for real life industrial *** disruption types are considered:jobs arrival and jobs ***,a Mixed Integer Linear Programming(MILP)model is developed,as well as an iterative predictive-reactive strategy for dealing with the online *** last,two heuristic methods are proposed and discussed,in terms of solution quality and computing time.

关键词： Rescheduling flowshop predictive-reactive strategy weighted waiting time stability weighted completion time deviation

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High-temperature investigation of mould slag crystallization by single and double hot thermocouple techniques

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Journal of Iron and steel Research International 2019年第4期26卷 345-354页

作者： nathalie Kolbl Irmtraud Marschall Harald Harmuth Department Mineral Resources Engineering Chair of CeramicsMontanuniversitaet LeobenLeoben 8700StyriaAustria

Methods for the characterization of mould slag crystallization with special emphasis on the single/double hot thermocouple technique(SHTT/DHTT)are *** the continuous casting process of steels,horizontal heat transfer is mainly influenced by the crystallization behaviour of the mould flux ***,both precipitation of crystals out of a liquid phase and devitrification of the glassy film in contact with the mould are of main ***,various investigation methods are implemented to characterize different slag properties related to crystallization:a viscometer for determining the break temperature,differential thermal analysis(DTA),confocal scanning laser microscopy,and the water-cooled copper finger *** near-service conditions,DHTT reveals the most detailed information,including not only the crystallization or devitrification temperature but also the morphology as well as the crystallization *** to improvements in the device and the representation of the results,a comparison of different samples is ***,the application field of SHTT/DHTT is restricted to slag systems with low contents of evaporating ***,the time required for data analysis is significantly longer than that required for other methods,***,the application of DHTT is mainly advisable for mould slag research and development,whereas DTA can also be used for incoming inspections.

关键词： Single hot thermocouple technique Double hot thermocouple technique Mould slag Near-service condition In situ investigation Crystallization

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