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Multi-phase post-mortem CT-angiography： a pathologic correlation study on cardiovascular sudden death

Journal of Geriatric Cardiology 2016年第10期13卷 855-865页

作者： Emanuela Turillazzi Paola Frati natascha pascale Cristoforo Pomara Giampaolo Grilli Rocco Valerio Viola Vittorio Fineschi Section of Forensic Pathology Department of Clinical and Experimental Medicine University of Foggia Foggia Italy Department of Anatomy Histology Forensic Medicine and Orthopaedics Sapienza University of Rome Rome Italy Depariment of Anatomy University of Malta Malta Operative Unit of Radiodiagnostics Ospedali Riuniti Foggia Italy

Multi-phase post-mortem CT-angiography （MPMCTA） has the great potential to increase the quality of the postmortem investigation, especially in the area of sudden death; however, its role as routine complement to the pathology toolbox is still questioned as it needs to be further standardized. The aim of this study is to investigate the contribution of MPMCTA in cases of sudden unexplained death in adults and in particular in sudden cardiovascular death. Sixty-eight sudden unexpected deaths of adults were investigated at our institution between 2012 and 2013. Ten cases underwent MPMCTA and autopsy and were included in the study. Before the angiographic step by complete filling of the vascular system, prior to any manipulation of the body, a non-contrast CT-scan was carried out. Image reconstructions were performed on a CT workstation （Vitrea） and two radiologists experienced with post mortem imaging interpreted the MPMCTA findings. In all 10 cases, we could state a good correlation between combination of post-mortem CT and MPMCTA and autopsy procedures, confirming a high diagnostic sensitivity. With this case series we want to illustrate the advantages offered by performing MPMCTA when facing a sudden death, regardless of specific suspicion for acute coronary syndrome or other vascular or ischemic disease.

关键词： Angiography Imaging Sudden death

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