检索结果-南通市图书馆

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

印度养鸡场:抗生素滥用与超级“耐药菌”

农经 2017年第8期 92-93页

作者： natalie obiko pearson Jason Gale 程玺

根据7月20日发表在《环境与健康展望》（EnvironmentalHealthPerspectives）月刊上的一份研究，对印度西北部旁遮普邦的18座各有约5万只鸡的养鸡场的随机检查显示出，三分之二的鸡只都感染了能产生一种特殊酶的细菌，这种酶被称为广谱β... 详细信息

根据7月20日发表在《环境与健康展望》（EnvironmentalHealthPerspectives）月刊上的一份研究，对印度西北部旁遮普邦的18座各有约5万只鸡的养鸡场的随机检查显示出，三分之二的鸡只都感染了能产生一种特殊酶的细菌，这种酶被称为广谱β-内酰胺酶（ESBL）,它能破坏多数青霉素类和头孢菌素类的抗生素。在接受检测的所有肉鸡中，87%的肉鸡含有这种超级细菌，而在蛋鸡中这一比例为42%。

关键词：抗生素滥用养鸡场印度头孢菌素西北部青霉素细菌肉鸡

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

加拿大版淘宝在美国对阵亚马逊

商业周刊（中文版） 2020年第10期 20-21页

作者： natalie obiko pearson Divya Balji 杜然(译) 不详

在4月初,英国的消费者因为疫情难以买到食品杂货,亨氏(Heinz)决定开设它的首家网店。数天的工夫,这个拥有151年历史的食品品牌就建起了一个出售各种豆类、意面圈圈和番茄汤的网站,英国境内送货上门。这家网店的生意非常好,亨氏立即扩大... 详细信息

在4月初,英国的消费者因为疫情难以买到食品杂货,亨氏(Heinz)决定开设它的首家网店。数天的工夫,这个拥有151年历史的食品品牌就建起了一个出售各种豆类、意面圈圈和番茄汤的网站,英国境内送货上门。这家网店的生意非常好,亨氏立即扩大商品种类,加入了该品牌的招牌调味料和婴儿食品。

关键词：食品品牌网店淘宝婴儿食品商品种类亚马逊送货上门加拿大

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

温哥华港厂房变豪宅，“生活方式泡沫”浮现

商业周刊（中文版） 2016年第16期 42-44页

作者： natalie obiko pearson 徐安琪

温哥华楼市是北美最炙手可热的楼市之一，数百万美元的推倒重建新屋比比皆是；房价之高，年轻人和中产阶级只能望楼兴叹。然而，叫苦不迭的不仅仅是想要买房的人。

关键词：温哥华港生活方式豪宅厂房泡沫中产阶级楼市美元

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

留学?移民?去加拿大吧

商业周刊（中文版） 2019年第5期 33-34页

作者： natalie Wong Theophilos Argitis natalie obiko pearson Erik Hertzberg Sandrine Rastello 竹西(译) 不详

在加尔各答长大的艾莎·乔克哈尼(Ayesha Chokhani)并不喜欢寒冷的天气。然而,当她攻读硕士学位时,这位29岁的学生选择了多伦多大学,那里的冬季气温远低于冰点。

关键词：加拿大留学移民多伦多大学加尔各答硕士学位学生选择

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

加拿大石油公司出奇招新技术带动盈利增长

商业周刊（中文版） 2017年第19期 31-31页

作者： Kevin Orland natalie obiko pearson 竹西

在加拿大阿尔伯塔省森科能源（Suncor Energy Inc．）的北陡河岸油砂矿（North Steepbank），一次性少量开采几吨原油的未来即将实现。在这里，人工操作的挖掘机刮掉顶层土壤，以与往常一样的方式挖出下面的富烃焦油砂。但接下来，它们... 详细信息

在加拿大阿尔伯塔省森科能源（Suncor Energy Inc．）的北陡河岸油砂矿（North Steepbank），一次性少量开采几吨原油的未来即将实现。在这里，人工操作的挖掘机刮掉顶层土壤，以与往常一样的方式挖出下面的富烃焦油砂。但接下来，它们将这些焦油砂倾倒在无人驾驶的卡车中，这些卡车使用GPS系统和激光在庞大的矿山中来回穿行。作为一项持续多年的测试的一部分，这些卡车只是森科和其他油砂生产商试图降低生产成本的努力之一。传统上，油砂开采是原油开采中最昂贵的一种方式。

关键词：加拿大大石油公司盈利增长新技术原油开采出奇阿尔伯塔省 GPS系统

Ribosomal proteins and human diseases:molecular mechanisms and targeted therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2021年第9期6卷 2748-2769页

作者： Jian Kang natalie Brajanovski Keefe T.Chan Jiachen Xuan Richard B.pearson Elaine Sanij Division of Cancer Research Peter MacCallum Cancer CentreMelbourneVICAustralia Sir Peter MacCallum Department of Oncology University of MelbourneMelbourneVICAustralia Department of Biochemistry and Molecular Biology Monash UniversityClaytonVICAustralia Department of Biochemistry and Molecular Biology University of MelbourneMelbourneVICAustralia Department of Clinical Pathology University of MelbourneMelbourneVICAustralia St.Vincent's Institute of Medical Research FitzroyVICAustralia

Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell growth and *** ribosomal proteins(RPs),comprising the structural parts of the ribosome,are essential for ribosome assembly and *** addition to their canonical ribosomal functions,multiple RPs have extra-ribosomal functions including activation of p53-dependent or p53-independent pathways in response to stress,resulting in cell cycle arrest and *** in ribosome biogenesis,translation,and the functions of individual RPs,including mutations in RPs have been linked to a diverse range of human congenital disorders termed *** are characterized by tissue-specific phenotypic abnormalities and higher cancer risk later in *** discoveries of somatic mutations in RPs in multiple tumor types reinforce the connections between ribosomal defects and *** this article,we review the most recent advances in understanding the molecular consequences of RP mutations and ribosomal defects in ribosomopathies and *** particularly discuss the molecular basis of the transition from hypo-to hyper-proliferation in ribosomopathies with elevated cancer risk,a paradox termed"Dameshek's riddle."Furthermore,we review the current treatments for ribosomopathies and prospective therapies targeting ribosomal *** also highlight recent advances in ribosome stress-based cancer ***,insights into the mechanisms of resistance to therapies targeting ribosome biogenesis bring new perspectives into the molecular basis of cancer susceptibility in ribosomopathies and new clinical implications for cancer therapy.

关键词： elevated mechanisms consequences

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

时尚填埋场

商业周刊（中文版） 2022年第24期 56-61页

作者： natalie obiko pearson Ekow Dontoh Dhwani Pandya 汪泽(译) 不详

在一加纳的海岸沿线,浸水的衣物纠结缠绕,在波浪中翻滚,如同尸体。加纳是世界最大的旧衣物进口国之一。这些废旧衣物成捆地被运到加纳,在此地被称为obroni wawu,意思是白人死者的衣服,这个词是当地的契维语,试图为这种来自海外的令人费... 详细信息

在一加纳的海岸沿线,浸水的衣物纠结缠绕,在波浪中翻滚,如同尸体。加纳是世界最大的旧衣物进口国之一。这些废旧衣物成捆地被运到加纳,在此地被称为obroni wawu,意思是白人死者的衣服,这个词是当地的契维语,试图为这种来自海外的令人费解的大量服装给出一个因由。这些衣服的主人肯定不会是主动扔掉这么多衣服的吧?

关键词：时尚废旧衣物加纳衣服服装填埋场浸水

Therapeutic response in children with ADHD: role of observers and settings

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2020年第3期16卷 314-321页

作者： Venkat Bhat Sarojini MSengupta natalie Grizenko Ridha Joober Douglas Mental Health University Institute FBC Building6875 Boul.LaSalleVerdunQC H4H 1R3Canada Department of Psychiatry University of TorontoTorontoCanada Department of Psychiatry McGill UniversityMontrealCanada Department of Neurology and Neurosurgery McGill UniversityMontrealCanada Department of Human Genetics McGill UniversityMontrealCanada

Background This study aims at characterizing the extent of correlation of treatment response (TR) obtained in various observation settings (home,school,clinic) by different observers (parents,teachers,clinicians).Methods Children with attention deficit hyperactivity disorder (ADHD) underwent a 2-week double-blind,randomized,cross-over clinical trial with methylphenidate and placebo,and various measures were obtained during the 2 *** of TR were examined using pearson's correlation *** The study included 526 children (420 male,106 female) with *** between different observers shows a variable correlation between parents and *** correlation is seen between parents/teacher evaluation of TR and laboratory-based measures (Continuous Performance Task;Restricted Academic Situation Scale).Conclusion The results firmly support the need to synthesize information from many sources in evaluating TR in ADHD.

关键词： ADHD Methylphenidate Parents Teachers Treatment response

The Use of Neupogen (Filgrastim) or Neulasta (Pegfilgrastim) during Pregnancy When Chemotherapy Is Indicated for Maternal Cancer Treatment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cancer Therapy 2012年第2期3卷 157-161页

作者： Elyce Cardonick Farhana Irfan natalie Torres Cooper University Hospital Cooper Medical School at Rowan Camden USA Cooper University Hospital Cooper Medical School at Rowan Camden USA.

Introduction: Little is known about the effects stem cell mobilizers (GCSF) such as neulasta (pegfilgrastim) or neupogen (filgrastim) during pregnancy, and these are often withheld from women undergoing chemotherapy during pregnancy. Materials and Methods: Women receiving chemotherapy during pregnancy were identified from the Cancer and Pregnancy Registry maintained at Cooper University Hospital, Cooper Medical School at Rowan. 176 pregnant women who received chemotherapy were identified. Their oncologists were asked if neupogen or neulasta were “prescribed when necessary;” “were not necessary;” or “were held due to pregnancy.” Birth outcomes, white blood count at birth and pediatric health were compared between the group receiving Neupogen/Neulasta (exposed) and a control group (unexposed), i.e. chemotherapy without neupogen/neulasta). Independent T Test or pearson Chi Square were implemented for statistical comparisons. Results: The mean gestational age at delivery was not significantly different between the exposed (35.4 ± 2.8 weeks) and unexposed groups (35.9 ± 2.8 weeks) p = 0.465. The mean birth weights were not significantly different, 2433 ± 567 g (exposed) compared with 2673 ± 723g in unexposed group, p = 0.07. Nor was there a difference in congenital malformations: 11.7% versus 4.8%. p = 0.22. The incidence of non-iatrogenic preterm births or complications was not statistically different between groups. Mean WBC count in the exposed group was 13.04 ± 5.0 cells per cubic millimeter of blood and in the unexposed group was 14.6 ± 7.2, p = 0.24. Conclusion: We did not find a statistically significant difference in gestational age at birth, congenital anomalies, or birth weight, incidence of long term medical issues, mean WBC or neutropenia at birth between the newborns exposed to Neupogen/ Neulasta with chemotherapy and newborns exposed to chemotherapy alone.

关键词： Neurogen Neulasta Chemotherapy Pregnancy