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Centrali.ed QoS Routi.g Model for Delay/Loss Sensi.i.e Flows at the SDN-i.T i.frastructure

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Computers, Materi.ls & Conti.ua 2021年第12期69卷 3727-3748页

作者： Mykola Beshley natalia Kryvi.ska Halyna Beshley Mykhai.o Medvetskyi.Leonard Barolli Department of Telecommuni.ati.ns Lviv Polytechnic National UniversityLviv79013Ukraine Department of i.formati.n Systems Faculty of ManagementComenius University in BratislavaBratislava82005Slovakia Department of i.formati.n and Communi.ati.n Engi.eeri.g Faculty of Information EngineeringFukuoka Institute of Technology(FIT)Higashi-Ku811-0295FukuokaJapan

The rapi.ly i.creasi.g number of i.ternet of Thi.gs(i.T)devi.es and Quali.y of Servi.e(QoS)requi.ements have made the provi.i.ni.g of network soluti.ns to meet thi. demand a major research *** fast and reli.ble routi.g paths based on the QoS requi.ements of i.T devi.es i. very i.portant task for i.dustry *** software-defi.ed network i. one of the most current i.teresti.g research developments,offeri.g an effi.i.nt and effecti.e soluti.n for centrali.ed control and network i.telli.ence.A new SDN-i.T paradi.m has been proposed to i.prove network QoS,taki.g advantage of SDN archi.ecture i. i.T *** the present ti.e,most publi.h-subscri.e i.T platforms assume the same QoS requi.ements for all ***,i. many real-world scenari.s of i.T appli.ati.ns,di.ferent subscri.ers may have di.ferent E2E delay *** reli.ble di.ferenti.ted servi.es has become a relevant *** thi. we developed a techni.ue for classi.yi.g i.T flows wi.h the i.di.i.ual subscri.er recommendati.n on the i.portance of certai. parameters for parti.ular classes of traffi. taken i.to *** i.prove the QoS for mi.si.n-cri.i.al i.T appli.ati.ns i. large-scale SDN-i.T i.frastructure,we focused on opti.i.i.g routi.g i. the *** thi. purpose,a centrali.ed routi.g model based on QoS parameters and i.T pri.ri.y flow for the SDN was proposed and *** have compared the proposed routi.g model wi.h the state-of-art determi.i.ti. multi.onstrai.ed centrali.ed QoS routi.g model(DMCQR).The developed centrali.ed routi.g model i. compari.on wi.h the known DMCQR flow routi.g achi.ved better balance of channel resources load due to rati.nal choi.e of transmi.si.n paths for di.ferent *** i. was possi.le to reduce up to 3 ti.es the average delay of real ti.e flows servi.e from end to end,for whi.h wi.h the exi.ti.g DMCQR routi.g model the permi.si.le delay rates were not met.

关键词： i.ternet of thi.gs software defi.ed networki.g quali.y of servi.es routi.g i.ternet of vi.eo thi.gs

Ri.ampi.i. qui.one pretreatment i.proves neuronal survi.al by modulati.g mi.rogli. i.flammati.n i.duced by α-synuclei.

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Neural Regenerati.n Research 2020年第8期15卷 1473-1474页

作者： Leonardo Acuna natalia S.Corbalán Ri.a Rai.man-Vozari Consejo Naci.nal de i.vesti.aci.nes Ci.ntífi.as y Técni.as(CONi.ET) Universidad Nacional de Salta(UNSa)SaltaArgentina i.sti.ut du Cerveau et de la Moelleépi.i.re(i.M) Inserm U 1127CNRS UMR 7225Sorbonne UniversitéParisFrance

The World Health Organi.ati.n has predi.ted that neurodegenerati.e di.eases affecti.g the motor functi.n wi.l become the second most prevalent cause of death i. the next 20 *** therapi.s can result from three mai. sources:syntheti. compounds,natural products,and exi.ti.g ***’s di.ease(PD)i. a common neurodegenerati.e di.ease affecti.g 1–3%of the adult populati.n over 50 years of age *** i. i.i.i.lly characteri.ed by the death of dopami.ergi. neurons i. the substanti. ni.ra pars compact and later by the wi.espread loss of nondopami.ergi. neurons,i.cludi.g those i. the cortex.

关键词： i.flammati.n death drugs

A New Speci.s of Japalura(Agami.ae: Lacerti.i.: Repti.i.) from Central Hi.hland,Vi.tnam

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Asi.n Herpetologi.al Research 2017年第1期18卷 14-21页

作者： natalia B.ANANJEVA Ni.olay L.ORLOV Tao Thi.n NGUYEN Department of Herpetology Zoological InstituteRussian Academy of Sciences Vi.tnam Nati.nal Museum of Nature Vietnam Academy of Science and Technology

A new speci.s of the agami. genus Japalura i. descri.ed based on three speci.ens from southern part of Central Vi.tnam. i. i. di.ti.gui.hed from remai.i.g congeners by the followi.g combi.ati.n of characters： adult si.e （SVL females 68-69 mm）, tai. length/SVL rati. 226%-239%, HW/SVL rati. 17%-18%; FLL/SVL rati. 41%43%; HLL/SVL rati. 72%-73%; 7-9 supralabi.ls, 7-9 i.fralabi.ls, 54-56 mi.dorsal scales, 20-22 lamellae under fi.ger i., 24-26 lamellae under toe i., 1 scale between nasal and supralabi.ls; tympanum concealed; absence of transverse gular fold. The geographi.al di.tri.uti.n of Japalura genus i. general and of a new speci.s i. parti.ular i. di.cussed.

关键词： Agami.ae Japalura taxonomy Vi.tnam descri.ti.n of a new speci.s di.tri.uti.n

Chondroi.i. sulfate and glucosami.e combi.ati.n i. pati.nts wi.h knee and hi. osteoarthri.i.:A long-term observati.nal study i. Russi.

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World Journal of Orthopedi.s 2023年第6期14卷 443-457页

作者： Alexander M Li.a Lyudmi.a i.Alekseeva Andrey A Baranov Elena A Taski.a Natalya G Kashevarova natalia A Lapki.a Evgeny A Trofi.ov Di.ector Research Institute of Rheumatology Named after VA NasonovaMoscow 115522MoscowRussia Bone and Joi.ts Metaboli. Di.eases Laboratory Research Institute of Rheumatology Named after VA NasonovaMoscow 115522MoscowRussia Department of Therapy Clinical Laboratory Diagnostics and Medical BiochemistryYaroslavl State Medical UniversityYaroslavl 150000YaroslavlRussia Department of Therapy and Rheumatology North-Western State Medical University named after I.I.MechnikovSt.Petersburg 191015St.PetersburgRussia

BACKGROUND Oral treatment of glucosami.e(GA) combi.ed wi.h chondroi.i. sulfate(CS) was reportedly effecti.e for pai. reli.f and functi.n i.provement i. osteoarthri.i. pati.nts wi.h moderate to severe knee pai. i. cli.i.al tri.ls. Whi.e the effecti.eness of GA and CS on both cli.i.al and radi.logi.al fi.di.gs has been demonstrated, only a few hi.h-quali.y tri.ls exi.t. Therefore, controversy regardi.g thei. effecti.eness i. real-world cli.i.al practi.e *** To i.vesti.ate the i.pact of GA + CS on cli.i.al outcomes of pati.nts wi.h knee and hi. osteoarthri.i. i. routi.e cli.i.al *** A multi.enter prospecti.e observati.nal cohort study i.cluded 1102 pati.nts of both genders wi.h knee or hi. osteoarthri.i.(Kellgren & Lawrence grades Ⅰ-Ⅲ) i. 51 cli.i.al centers i. the Russi.n Federati.n from November 20, 2017, to March 20,2020, who had started to recei.e oral capsules of glucosami.e hydrochlori.e 500 mg and CS 400mg accordi.g to the approved pati.nt i.formati.n leaflet starti.g from 3 capsules dai.y for 3 wk,followed by a reduced dosage of 2 capsules dai.y before study i.clusi.n(mi.i.al recommended treatment durati.n i. 3-6 mo). Changes i. subscale scores [Pai., Symptoms, Functi.n, and Quali.y of Li.e(QOL)] of the Knee i.jury and Osteoarthri.i. Outcome Score(koOS)/Hi. Di.abi.i.y and Osteoarthri.i. Outcome Score(HOOS) questi.nnai.es duri.g the observati.nal peri.d(up to 54-64wk wi.h a total of 4 vi.i.s). Pati.nts’ treatment sati.facti.n, data on the combi.ed oral use of glucosami.e hydrochlori.e and CS, concomi.ant use of non-steroi.al anti.i.flammatory drugs(NSAi.s), and adverse events(AEs) were also *** A total of 1102 pati.nts wi.h knee and hi. osteoarthri.i. were i.cluded i. the study. The mean pati.nt age was 60.4 years, most pati.nts were women(87.8%), and thei. average body mass i.dex was 29.49 kg/m2. All subscale scores(Pai., Symptoms, Functi.n, and QOL) of the koOS and HOOS demonstrated cli.i.ally and stati.ti.ally si.ni.i.ant i.

关键词： Glucosami.e Chondroi.i. sulfate Knee osteoarthri.i. Hi. osteoarthri.i. Knee i.jury and osteoarthri.i. outcome score Hi. di.abi.i.y and osteoarthri.i. outcome score

Response to li.opolysacchari.e i. Octodon degus pups produces age-related si.kness behavi.r but does not have effects i. juveni.es

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i.tegrati.e Zoology 2019年第3期14卷 235-247页

作者： natalia RAMi.EZ-OTAROLA Janyra ESPi.OZA Alexi. M.KALERGi. Pablo SABAT Department of Ecologi.al Sci.nces Science FacultyUniversidad de ChileSantiagoChile Mi.lenni.m i.sti.ute i.munology and i.munotherapy Departamento de Genética Molecular y MicrobiologíaFacultad de Ciencias BiológicasPontificia Universidad Católica de ChileSantiagoChile Departamento de Endocri.ología Facultad de MedicinaPontificia Universidad Católica de ChileSantiagoChile Department of Ecology Center of Applied Ecology&SustainabilityBiological Sciences FacultyPontificia Universidad Católica de ChileSantiagoChile

Duri.g vertebrate development,the i.mune functi.n i. i.effi.i.nt and i. mai.ly controlled by i.nate *** there have been detai.ed studi.s of vari.us aspects of i.nate i.mune functi.n,the effects of thi. functi.n i. the growth of vertebrates i. sti.l not well ***,there i. li.tle i.formati.n regardi.g how early endotoxi. exposure would affect juveni.e phenotypes,speci.i.ally i. a non-model mammal li.e a precoci.l *** evaluated the response to an anti.en and i.s cost i. offspri.g of the rodent Octodon *** i.oculated pups at 4 di.ferent ages(8,15,22 and 30 days after bi.th)wi.h an anti.en to determi.e the ontogeny and costs of the response to an *** assessed changes i. body mass,body temperature,si.kness behavi.r and the levels of a key medi.tor of the i.flammatory response,the cytoki.e i.terleuki.-1β.We also determi.ed the effects of early endotoxi. exposure on the resti.g metaboli. rate of juveni.e ani.als(i.e.90 days after bi.th).The cytoki.e levels,body mass and body temperature were unaffected by ti.e of i.oculati.n and ***,pups subjected to i.oculati.n at 22 days after bi.th wi.h the anti.en showed reduced loco*** resti.g metaboli. rate was not affected by early endotoxi. *** results suggest that the magni.ude of *** responses would not change wi.h *** di.cuss whether the lack of effect of the response on body mass or body condi.i.n i. caused by envi.onmental vari.bles or by the precoci.l characteri.ti.s of ***.

关键词： acute phase response ecoi.munology li.opolysacchari.e precoci.l si.kness behavi.r

Bi.chemi.al composi.i.n of the glomerular extracellular matri. i. pati.nts wi.h di.beti. ki.ney di.ease

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World Journal of Di.betes 2022年第7期13卷 498-520页

作者： María M Adeva-Andany natalia Carnei.o-Frei.e Nephrology Hospital Juan CardonaFerrol 15406Spain

i. the glomeruli.mesangi.l cells produce mesangi.l matri. whi.e podocytes wrap glomerular capi.lari.s wi.h cellular extensi.ns named foot processes and tether the glomerular basement membrane(GBM).The turnover of the mature GBM and the abi.i.y of adult podocytes to repai. i.jured GBM are *** acti. cytoskeleton i. a major cytoplasmi. component of podocyte foot processes and li.ks the cell to the *** components of the normal glomerular extracellular matri.(ECM)i.clude glycosami.oglycans,proteoglycans,lami.i.s,fi.ronecti.-1,and several types of *** pati.nts wi.h di.betes,multi.rgan composi.i.n of extracellular ti.sues i. anomalous,i.cludi.g the ki.ney,so that the consti.uti.n and arrangement of glomerular ECM i. profoundly *** pati.nts wi.h di.beti. ki.ney di.ease(DKD),the global quanti.y of glomerular ECM i. *** level of sulfated proteoglycans i. reduced whi.e hyaluroni. aci. i. augmented,compared to control *** concentrati.n of mesangi.l fi.ronecti.-1 vari.s dependi.g on the stage of *** type i.i.collagen i. abundant i. pati.nts wi.h DKD,unli.e normal *** amount of type V and type Vi.collagens i. hi.her i. DKD and i.creases wi.h the progressi.n of the *** GBM contai.s lower amount of type i. collagen i. DKD compared to normal ***,geneti. vari.nts i. theα3 chai. of type i. collagen may modulate suscepti.i.i.y to DKD and end-stage ki.ney *** cellular models of glomerular cells,analyses of human glomerular proteome,and i.proved mi.roscopy procedures have been developed to i.vesti.ate the molecular composi.i.n and organi.ati.n of the human glomerular ECM.

关键词： Di.betes Ki.ney di.ease Glycosami.oglycans Factor H Si.li. aci. Lami.i. Collagen Fi.ronecti.-1 Extracellular matri.

Novel Approaches of Usi.g of Spi.uli.a Platensi. i. Natural Rubber Based Composi.es

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Journal of Renewable Materi.ls 2018年第7期6卷 680-687页

作者： Ewa Głowi.ska Janusz Datta Pauli.a Parcheta and natalia Kaźmi.rczak Department of Polymers Technology Gdańsk University of TechnologyNarutowicza Street 11/1280-233 GdańskPoland

The ai. of thi. work was to i.vesti.ate the i.fluence of Spi.uli.a (Spi.uli.a platensi.) as a natural fi.ler on thecuri.g characteri.ati.n, morphology and mechani.al, thermomechani.al and thermal properti.s of naturalrubber (NR) based composi.es. Spi.uli.a was i.troduced i.to NR mi.ture i. amount of 0 phr, 10 phr and 30 *** vulcani.ati.n process was carri.d out at the determi.ed process condi.i.n by usi.g hydrauli. press atopti.um vulcani.ati.n ti.e (t90). i. was noti.ed that Spi.uli.a affected on the reducti.n of t90, and scorch ti.e(t2) of the NR mi.tures. Obtai.ed vulcani.ates were subjected to the number of tests e.g. scanni.g electronmi.roscopy analysi., mechani.al dynami.al analysi., tensi.e test, hardness, and thermogravi.etry. Generally, i.was found that Spi.uli.a added i. amount of 10 phr NR posi.i.ely i.fluenced on tensi.e strength (TSb), storagemodulus and hardness of obtai.ed composi.es.

关键词： Spi.uli.a algae natural rubber composi.es DMA

The “Brai. Stress Ti.i.g” phenomenon and other mi.i.terpretati.ns of randomi.ed cli.i.al tri.l on aneurysmal subarachnoi. hemorrhage

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Neural Regenerati.n Research 2019年第8期14卷 1364-1366页

作者： Rafael Marti.ez-Perez natalia Rayo Agusti. Monti.ero Jorge Marcelo Mura Di.i.i.n of Neurosurgery Institute of Clinical Neurosciences Universidad Austral de Chile Valdivia Chile Di.i.i.n of Cerebrovascular and Skull Base Neurosurgery Institute of Neurosurgery Dr Asenjo Santiago Chile Western Uni.ersi.y London ON Canada

Cli.pi.g and coi.i.g are currently the two alternati.es i. treatment of ruptured cerebral aneurysms. i. spi.e of some meri.ori.us analysi., further di.cussi.n i. helpful to understand the actual state of art. Retreatment and rebleedi.g rates clearly favors cli.pi.g, although short-term functi.nal outcome seems to be benefi.i.l for cli.pi.g, whi.e thi. di.ferent i. not such i. we perform the compari.on at a longer follow up. Longterm follow ups and cost analysi. are mandatory to have a clear vi.w of the current pi.ture i. treatment of subarachnoi. hemorrhage. Treatment strategy should be made by a multi.di.ci.li.ary team i. accredi.ed centers wi.h profi.i.nt experi.nce i. both techni.ues.

关键词： sAH subarachnoi. hemorrhage coi.i.g cli.pi.g ruptured aneurysm ti.i.g i.tracrani.l

Study of hi.h-speed i.teracti.n processes between fluoropolymer projecti.es and alumi.um-based targets

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Defence Technology（防务技术） 2015年第1期11卷 56-64页

作者： Evgeny A.KHMELNi.OV Alexey V.STYROV konstanti. V.SMAGi. natalia S.KRAVCHENko Valery L.RUDENko Vladi.i. i.FALALEEV Sergey S.SOkoLOV Artem V.SVi.i.SKY natalia F.SVi.i.SKAYA Ni.hny Tagi. Technologi.al i.sti.ute (Branch) of Ural Federal Uni.ersi.y Russian Federation Federal State Enterpri.e "Ni.hny Tagi. i.sti.ute of Metal Testi.g" Russian Federation All-Russi.n Sci.nti.i. Research i.sti.ute of Experi.ental Physi.s Sarov Russian Federation

The experi.ental results and numeri.al modeli.g of penetrati.n process of fluoropolymer projecti.es i. alumi.um-based targets are presented. Analysi. of mathemati.al models for i.teracti.n of elastoplasti. projecti.e and target wi.hout taki.g addi.i.nal energy released duri.g i.teracti.n of fluoropolymer and alumi.um i.to consi.erati.n i. carri.d out. Energy fracti.n whi.h i. spent effecti.ely on the i.crease i. cavi.y volume i. determi.ed. The experi.ental and calculated results of penetrati.n by combi.ed and i.ert projecti.es are compared.

关键词： Reacti.e materi.ls Fluoropolymer Hi.h speed strai. i.teracti.n Alumi.um Ti.ani.m alloy Numeri.al modeli.g