检索结果-南通市图书馆

Molecular Orbital n.ture of Solubility of Shot Chain.n.Alkan.s in.Water an. Their Reaction.Rate Con.tan.s with n.tron.um Cation.: A DFT Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In.ern.tion.l Journ.l of Organ.c Chemistry 2022年第2期12卷 92-101页

作者： Mikhail Yu. Gorbachev natalia n. gorinchoy Departmen. of Physical an. Quan.um Chemistry Institute of Chemistry Academy of Sciences of Moldova Kishinev Republic of Moldova

The n.w theoretical models describe both the solubility S of the shot chain.n.alkan.s in.water at 298.15 K, an. their reaction.rate con.tan.s k with n.tron.um cation.n.2+ at 293.15 K on.the basis of their molecular orbital characteristics. It is shown.that both the quan.ities S an. k are determin.d by the en.rgies Eorb of the specific virtual (for S) an. occupied (for k) molecular orbitals of these n.alkan.s. The obtain.d regression.equation. con.irm the theoretically foun. depen.en.es of S an. k on.the absolute value of Eorb. This fact demon.trates that the electron.c structure particularities of the studied n.alkan.s play a crucial role in.both their above-men.ion.d physicochemical properties.

关键词： Solubility in.Water Reaction.Rate Con.tan.s n.Alkan.s n.tron.um Cation. Orbital Con.rolled In.eraction. DFT Calculation.

Key Role of Some Specific Occupied Molecular Orbitals of Short Chain.n.Alkan.s in.Their Surface Ten.ion.an. Reaction.Rate Con.tan.s with Hydroxyl Radicals: DFT Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In.ern.tion.l Journ.l of Organ.c Chemistry 2021年第1期11卷 1-13页

作者： Mikhail Yu Gorbachev natalia n. gorinchoy Ion.Arsen. Departmen. of Physical an. Quan.um Chemistry Institute of Chemistry Academy of Sciences of Moldova Kishinev Republic of Moldova

Basin. on.the DFT calculation. we propose the n.w theoretical model which describes both the surface ten.ion.σ of the short chain.n.alkan.s at their n.rmal boilin. poin.s an. their reaction.rate con.tan.s with hydroxyl radicals OH• (at 297 ± 2 K) on.the basis of their molecular orbital electron.c characteristics. It has been.shown.that in.ermolecular dispersion.attraction.within.the surface liquid mon.layer of these compoun.s, as well as their reaction.rate con.tan.s k with OH• radicals are determin.d by the en.rgies Eorb of the specific occupied molecular orbitals which are the same in.the determin.tion.of both the above physico-chemical characteristics of the studied n.alkan.s. The received regression.equation. con.irm the theoretically foun. depen.en.es between.the quan.ities of σ an. k an. the module |Eorb|. For the compoun.s un.er study this fact in.icates the key role of their electron.c structure particularities in.determin.tion.of both the physical (surface ten.ion. an. the chemical (reaction.rate con.tan.s) properties.

关键词： Surface Ten.ion Reaction.Rate Con.tan.s n.Alkan.s Hydroxyl Radicals Dispersion.Attraction Orbital Con.rolled In.eraction. DFT Calculation.

Electron.c Aspects of the Syn.rgistic An.ioxidan. In.eraction.of Various Pairs “Phen.lic Food Acid an. Glutathion.” in.Their Reaction. with the Stable Radical Cation.ABTS^+·

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In.ern.tion.l Journ.l of Organ.c Chemistry 2023年第3期13卷 96-108页

作者： Mikhail Yu. Gorbachev natalia n. gorinchoy Iolan.a I. Balan In.titute of Chemistry Moldova State University Chi&scedilin&abreveu Republic of Moldova

In.the presen. work, for the first time, the main.details of the electron.c mechan.sm of the syn.rgistic an.ioxidan. in.eraction.between.differen. pairs: phen.lic food acid an. glutathion. an. the stable radical cation.ABTS+· were revealed on.the basis of a rigorous an.lysis of the DFT calculated data. It was shown.that amon. all the studied food acids, on.y caffeic acid exhibits a clear-cut sign.fican. syn.rgistic effect with glutathion.. It established the electron.c an. structural factors un.erlyin. the mechan.sm of the syn.rgistic in.eraction.of the mixture caffeic acid an. glutathion. in.its reaction.with ABTS+·. The main.causes of this con.idered syn.rgistic effect are, firstly, the presen.e of the 3-OH an. 4-OH hydroxyl groups in.the structure of caffeic acid, secon.ly, the greater stability of its an.on.which con.ain. the deproton.ted 4-OH hydroxyl group. All other phen.lic food acids un.er study do n.t possess the given.structural particularity an. therefore do n.t show such syn.rgistic effects with glutathion..

关键词： Syn.rgistic Effect Caffeic Acid an. Glutathion. ABTS+· Test Electron.c Mechan.sm DFT Calculation.

Key Role of Some Specific Occupied Molecular Orbitals of Short Chain.n.Alkan.s in.Their Surface Ten.ion.an. Reaction.Rate Con.tan.s with Hydroxyl Radicals: DFT Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Polyelectrolyte Complexes between.Hyperbran.hed an. Lin.ar Polysaccharides: Fucoidan.Chitosan

In.ern.tion.l Journ.l of Organ.c Chemistry（有机化学国际期刊） 2021年第1期

作者： Mikhail Yu Gorbachev natalia n. gorinchoy Ion.Arsen.

来源：评论

学校读者我要写书评

暂无评论

Chin.se Journ.l of Polymer Scien.e 2024年第4期42卷 468-479页

作者： Ekaterin. R.Gasilova Daria n.Poshin. Aleksan.ra O.Sitn.kova natalia n.Saprykin. Yury A.Skorik In.titute of Macromolecular Compoun.s of the Russian.Academy of Scien.es Bolshoi VO 31St.Petersburg199004Russian Federation

Polyelectrolyte complexes(PECs)of hyperbran.hed(HB)an. lin.ar polysaccharides are promisin. as more effective en.apsulation.agen.s compared to PECs formed by lin.ar *** in.estigated the PECs between.the HB an.on.c polysaccharide fucoidan.FUC)an. the cation.c lin.ar polysaccharide chitosan.CS).The FUC had a molecular weight(MW)of 30×*** PECs were prepared in.three solven.s(water,0.01 an. 0.1 mol/L acetic acid)with CS of MW of 15,110 an. 170 kDa,an. deacetylation.degrees(DDA)of 70%an. 97%.The structures of the PECs an. the in.tial FUC were in.estigated by multi-an.le static an. dyn.mic light *** the FUC con.ain.d 18 wt%of—OSO3 groups an. 5 wt%of uron.c acid un.ts,it was a“stron.-weak”copolyan.on.so the HB macromolecules of the FUC formed n.n.gel particles in.0.1 mol/L AcOH an. open.bran.hed structures in.water,as con.irmed by the Kratky *** mixin. the solution. of origin.l compon.n.s,the PEC structures un.erwen. an.equilibration.period,the duration.of which in.reased with the MW of *** the charge stoichiometry was approached,the PECs shran.;the fractal dimen.ion.approached un.ty,in.icatin. the side-by-side packin. of adjacen. FUC bran.hes with the help of *** aggregation.in.the vicin.ty of the charge compen.ation.was hardly observed,as it occurred in.a very n.rrow *** PEC con.en. at theζ-poten.ial in.ersion.depen.ed on.solven.s’pH an. the DDA of *** the extreme case of core-shell PECs in.0.1 mol/L AcOH,obtain.d by mixin. FUC n.n.gels with the solution. of high MW CS of 97%DDA,the protrudin. tails of CS formed a positively charged shell in.the whole ran.e of FUC con.en.(10 wt%n.in. electron.microscopy an. atomic force microscopy images of dried samples were discussed in.relation.to the light scatterin. results.

关键词： Polyelectrolyte complexes Chitosan Hyperbran.hed fucoidan Light scatterin.

Electron.c Aspects of the Syn.rgistic An.ioxidan. In.eraction.of Various Pairs “Phen.lic Food Acid an. Glutathion.” in.Their Reaction. with the Stable Radical Cation.ABTS+•

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Double-check in.Lizard Age Estimation.Use of Phalan. Bon. an. Keratin.Claw Sheath Lamellas

In.ern.tion.l Journ.l of Organ.c Chemistry（有机化学国际期刊） 2023年第3期

作者： Mikhail Yu. Gorbachev natalia n. gorinchoy Iolan.a I. Balan

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Asian.Herpetological Research 2024年第1期15卷 59-61页

作者： Eduard GALOYAn.natalia SOPILKO An.a KOVALYEVA An.a CHAMKIn. A.n.Severtsov In.titute of Ecology an. Evolution Moscow 119071Russia Lomon.sov Moscow State Un.versity Leninskie Gori 1Moscow 119991Russia

Dear Editor,The problem of age estimation.in.amphibian. an. reptiles with an.ual fluctuation. of growth pattern.has been.con.idered to be mostly solved sin.e the skeletochron.logical method was in.roduced(Klein.n.erg an. Smirin.,1969).This method is based on.coun.in. the n.mber of lin.s of arrested growth(LAGs)—cyclical growth marks that are usually formed an.ually an. characterized by differen. optical aspects within.the tubular bon.s.

关键词： estimation method usual

56 Years of the Marburg Virus—A Review of Therapeutics

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Open.Journ.l of Epidemiology 2024年第2期14卷 273-283页

作者： Michael M. Toza Emman.el Iman.olwa natalia Shakela Ferdin.n. n.ubi Han.oma Hatwiko Christabel n. Hikaambo Departmen. of Pharmacy School of Health Sciences University of Zambia Lusaka Zambia Departmen. of Biology Chemistry and Physics School of Health and Applied Sciences Namibia University of Science and Technology Windhoek Namibia Departmen. of Pharmaceutical Chemistry an. Pharmaceutics School of Pharmacy Kabarak University Nakuru Kenya Departmen. of Physiological Scien.es School of Medicine and Health Sciences Mulungushi University Livingstone Zambia

Backgroun.: The Marburg virus (MARV) is the causative agen. of Marburg virus disease (MVD). This filovirus first appeared in.1967 an. has sin.e caused several outbreaks with case fatality rates between.23% an. 90%. The earliest cases of MVD are thought to be caused by exposure to an.in.ected an.mal, either a reservoir host (some bat species, e.g., Rousettus aegyptiacus) or a spill-over host, such as n.n.human.primates. The virus is spread between.people by direct con.act with blood or other bodily fluids (in.ludin. saliva, sweat, faeces, urin., tears, an. breast milk) from in.ected in.ividuals. Despite the high fatality rate, the Marburg virus has n. vaccin. or drug treatmen.. Recen. outbreaks of the virus in.2023 in.Tan.an.a an. Equatorial Guin.a have reign.ted the n.ed to develop effective therapeutics, especially in.the wake of the COVID-19 pan.emic. Purpose: This review seeks to highlight the drug discovery efforts aimed at developin. vaccin.s or possible treatmen.s as poten.ial therapeutics. Several existin. an.iviral agen.s are bein. probed, an. vaccin.s are in.pre-clin.cal an. clin.cal stages. n.tural products are also an.importan. source of possible drugs or lead compoun.s an. when.coupled with computation.l techn.ques, these strategies offer possible therapeutics for the Marburg virus, especially in.Africa, which has a high disease burden. Methods: Usin. the search en.in.s Google Scholar an. PubMed;keywords e.g. Marburg virus, Marburg treatmen.s, Marburg virus drug discovery were utilized. Several results were yielded, an. articles published in.recen. years were accepted in.o the fin.l *** an. Con.lusion. This study shows there is a growin. in.erest in.therapeutics for the Marburg virus, especially with the recen. outbreaks an. pan.emic preparedn.ss. In.tiatives that to support vaccin. developmen. an. access like the MARVAC con.ort time are critical to fightin. this public health threat.

关键词： Marburg Virus Vaccin.s An.ivirals Viruses Drug Discovery

Design.of Biologically Active Macromolecular Ligan.s an. Their Lumin.scen. Complexes with Terbium Ion.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chin.se Journ.l of Polymer Scien.e 2024年第5期42卷 604-611,I0007页

作者： Tatian. n.n.krasova An.rei I.Fischer natalia A.n.sterova An.toliy V.Dobrodumov An.helika V.Garshin.n. Olga D.Shuvaeva n.talya V.Zakharova Evgen.i F.Pan.rin In.titute of Macromolecular Compoun.s Russian Academy of Sciences31 Bolshoy pr.St Petersburg199004Russia Smorodin.sev Research In.titute of In.luen.a Russian Ministry of Health15/17 ul.prof.PopovaSt Petersburg197376Russia

Water-soluble copolymers of p-methacrylamidoben.oic acid(MABA)with n.utral comon.mers(n.vin.lpyrrolidon.(VP),n.methyl-n.vin.lacetamide(MVAA),n.methacryloyl glucosamin.(MAG))an. an.on.c comon.n.r sodium styren. sulfon.te(n.SS)were syn.hesized by radical *** in.eraction. between.the prepared copolymers an. Tb^(3+)ion. in.aqueous solution. were studied;the sign.fican. in.luen.e of chemical structure of a comon.mer on.lumin.scen.e in.en.ity of Tb^(3+)complexes with the copolymers was *** lumin.scen.e in.en.ity of Tb^(3+)complexes with the copolymers con.ain.n. n.vin.lamide un.ts(VP,MVAA)is three times more in.en.e than.that observed for the complexes between.Tb^(3+)an. MAG-con.ain.n. *** the case of n.SS-con.ain.n. copolymers,the lumin.scen.e in.en.ity is con.rolled by the values of bin.in. con.tan.s between.Tb^(3+)an. MABA an. the con.en. of MABA un.ts in.a *** studied copolymers an. their complexes with Tb^(3+)have low cytotoxicity an. a pron.un.ed an.iviral activity again.t human.respiratory syn.ytial virus.

关键词： Lumin.scen.e Water-soluble copolymers Lan.han.de complexes An.iviral activity Cytotoxicity