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Green Synthesis of New Tetra Schiff Bases and Bis-Azo Bis-Schiff Bases Derived from 2,6-Diaminopyridine as Promising Photosensitizers

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International Journal of Organic Chemistry 2018年第3期8卷 309-318页

作者： Nihad I. Taha nashwan O. Tapabashi Marwa N. El-Subeyhi Department of Chemistry College of Science University of Kirkuk Kirkuk Iraq

Nine new tetra Schiff bases (M2 - M9) were prepared in moderate yields via the condensation of different aromatic amines and bis-Schiff base (M1) in microwave synthesizer. Also five new azo-Schiff bases (M16 - M20) were prepared by the condensation of (M1) with the azo-salicylaldehyde (M11 - M15) using the same method. The green synthesis by microwave irradiation was chosen as route due to its novelty, cleanliness, efficiency, time and solvent saving properties compared with the conventional methods which lack these advantages;such as time consume and wasting environment polluting organic solvents to achieve the same efficiency in synthesis. The prepared compounds which are believed by us to be competent as photosensitizers in photochemical systems were identified by IR and NMR spectroscopy besides elemental analysis.

关键词： Schiff Base Azo-Schiff Base 2 6-Diaminopyridine Azo-Salicyladehyde Photosensitizer

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Development of Nursing Research in Qatar: 15-Year Status Report

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Open Journal of Nursing 2017年第2期7卷 242-252页

作者： Abdulqadir J. nashwan Dana B. Mansour Abdulkarim Alzayyat Sindhumole K. Nair Amer I. Zawahreh National Center for Cancer Care & Research (NCCCR)-Hamad Medical Corporation (HMC) Doha Qatar University of Calgary Doha Qatar Qatar Cancer Society Doha Qatar College of Nursing University of Florida Gainesville FL USA

Purpose: The aim was to provide an overview of nursing research in Qatar over the previous 15 years. Methods: Several online databases were searched for published articles between 2000 and 2015 related to nursing research in Qatar. Findings: The initial search identified 6540 articles, whose titles, abstracts, and texts were screened for satisfying the eligibility criteria. Only 57 articles met the eligibility criteria. The highest percentage of studies (42%) focused on clinical practice issues. Eighty-seven percent (87%) were published in peer-reviewed journals;84% (N = 48) were conducted between 2011 and 2015 with 16-fold growth rate compared to 2000-2005. The majority of authors were postgraduate qualified nurses, mainly 67% of them with hospital and academic affiliation (88%). The vast majority of identified studies were conducted in hospital settings (63%), and only 14% of the studies used a nursing theory or conceptual framework. Sixty-three percent (63%) of the studies were quantitative, and 25% were funded mostly by hospitals. The majority of the included studies have been done in collaboration with other disciplines (60%), especially with physicians (65%). Conclusion: Nursing research in Qatar has dramatically developed and improved over the last 15 years. However, nurses need to be more motivated to conduct and publish research in collaboration with national, regional, and international research bodies. Implications for Nursing & Health Policy: Building and sustaining nursing research infrastructure considered as a top priority for nursing leaders, academic, and ministry of public health in Qatar. Furthermore, preparing nurses with higher academic degrees is an essential step in advancing research utilization in Qatar and the region.

关键词： Literature Review Nursing Research Nurses Qatar

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Pulmonary Hypertension Induced by Thalidomide (and Derivatives) in Patients with Multiple Myeloma: A Systematic Review

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Journal of Cancer Therapy 2016年第13期7卷 971-978页

作者： Abdulqadir J. nashwan Nader I. Al-Dewik Hisham M. Al Sabah Mohamed A. Yassin Shehab F. Mohamed Nabil H. Omar Dana B. Mansour National Center for Cancer Care & Research (NCCCR)-Hamad Medical Corporation Doha Qatar University of Calgary Doha Qatar Qatar Medical Genetics Center Hamad General Hospital (HGH) Hamad Medical Corporation (HMC) Doha Qatar Interim Translational Research Institute (iTRI) HMC Doha Qatar Medical Oncology/Hematology Department National Center for Cancer Care and Research Hamad Medical Corporation Doha Qatar National Center for Cancer Care & Research (NCCCR)-Hamad Medical Corporation Doha Qatar Qatar Cancer Society Doha Qatar

Thalidomide is widely used in the treatment of multiple myeloma (MM). In recent years, several cases of pulmonary hypertension have been reported following treatment with thalidomide. The aim of this review was to evaluate the published literature on multiple myeloma patients with pulmonary hypertension following thalidomide treatment. A literature search was performed between 2000 and 2016. A total of 7 eligible studies were identified and deemed eligible, including 11 cases—approximately 37% (4 cases) with IgA (k), 27% (3 cases) with IgG (λ) MM, 27% (3 cases) with IgG (k) MM, and one case (9%) with primary plasma cell leukemia (PPCL). The vast majority of cases—82% (9 cases)—are associated with thalidomide, while only 18% (2 cases) are related to thalidomide derivatives (lenalidomide and pomalidomide). In conclusion, pulmonary hypertension induced by thalidomide or derivatives in multiple myeloma (MM) patients is related to a multifactorial etiology including the pathophysiology of the disease, thromboembolic events, preexisted cardiovascular conditions, comorbidities, and combination with other chemo- or bio-therapeutic agents. MM patients should be evaluated for signs and symptoms underlying cardiopulmonary disease before initiating, and during treatment with thalidomide.

关键词： Thalidomide Thalidomide Derivatives Pulmonary Hypertension Multiple Myeloma

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The Burnout among Multinational Nurses in Saudi Arabia

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Open Journal of Nursing（护理学期刊） 2019年第7期

作者： Maram Hani Batayneh Shaukat Ali Abdulqadir J. nashwan

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Design, Microwave Assisted Synthesis of Some Schiff Bases Derivatives of Congo Red and Conventional Preparation of Their Structurally Reversed Analogous Compounds

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International Journal of Organic Chemistry（有机化学国际期刊） 2021年第1期

作者： nashwan O. Tapabashi Nihad I. Taha Marwa El-Subeyhi

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Pulmonary Hypertension Induced by Thalidomide (and Derivatives) in Patients with Multiple Myeloma: A Systematic Review

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Journal of Cancer Therapy（癌症治疗） 2016年第13期

作者： AbdulqadirJ.nashwan NaderI.Al-Dewik HishamM.AlSabah MohamedA.Yassin ShehabF.Mohamed NabilH.Omar DanaB.Mansour

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