检索结果-南通市图书馆

Foaming supramolecular surfactants for gas mobility control in naturally fractured carbonate reservoirs at high temperature,salinity,and hardness

引用

Petroleum Science 2022年第6期19卷 3134-3148页

作者： Enrique Soto-Castruita raúl Hern andez-Altamirano Eduardo Buenrostro-González Erick-Emanuel Luna-Rojero Sung Jae ko-Kim Violeta-Yasmín Mena-Cervantes Mirna Pons-Jiménez Jorge-Francisco ramírez-Pérez David-Aaσn Nieto-Alvarez Ricardo Cerón-Camacho Jos e-Ernesto Parra raúl Oviedo-Roa Jos e-Manuel Martínez-Magadán Rodolfo Cisneros-Dévora Luis-S.Zamudio-Rivera Instituto Mexicano del Petr oleo Eje Central Lazaro Cardenas Norte 152Col.San Bartolo AtepehuacanCiudad de Mexico07730Mexico CONACy T-Instituto Mexicano del Petroleo Eje Central Lazaro Cardenas Norte 152Col.San Bartolo AtepehuacanCiudad de Mexico07730Mexico Centro Mexicano para la Produccion mas Limpia Instituto Politecnico NacionalAvenida Acueducto s/nCol.La Laguna TicomanCiudad de Mexico07340Mexico Centro de Tecnologías para Exploracion y Produccion Camino de Terracería 800Col.San Jose NovilleroBoca delRíoVeracruz94286Mexico

Oil production and mainte nance are essential issues in naturally fractured reservoirs because they are the largest and most productive on ***,they present early water and gas channeling but could be remediated by using foaming agents to control these phenomena through blocking channeling *** Mexico these reservoirs have pressure up to 5,500 psi,high temperature up to 200℃,salinity up to400,000 ppm,and hardness up to 250,000 ppm;due to these thermodynamic conditions,there has been no available technology to form stable enough *** this work,a foaming supramolecular surfactant with the capability to chelate Ca^(2+)ions is *** a result,surfactant monomers are bridged by captured Ca^(2+)cations leading to the formation of high-molecular-weight oligomers,which significantly increment the viscosity of the solution improving the foam stability,and since at this manner the Ca2+cations are no longer available to precipitate as components of solid salts,the foaming supramolecular surfactant also performs as *** observations are explained through quantum theoretical *** foam is stable,effectively blocking the gas channels,whereas in presence of oil the foam is broken leading the oil to pass into the *** characteristic rheological properties of the foam allow its injection into the formation at a range of flow rates,foam qualities,and shear stress to achieve the flooding and the blocking of a variety of fractured carbonate formations,and the change of the wettability of the matrix,which is a desirable behavior in a huff and puff process,as reported in a previous publication about a successful pilot test of this foam.

关键词： Calcium chelation Foaming composition Supramolecular surfactant Molecular design Gas mobility control Flow assurance Improved oil recovery Conformance control

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ameliorative effects of human adipose tissue-derived mesenchymal stem cells on myelin basic protein-induced experimental autoimmune encephalomyelitis in Lewis rats

引用

Neural Regeneration Research 2011年第16期6卷 1205-1210页

作者： Myung-Soon ko Hyeong-geun Park Young-Min Yun Jeong Chan ra Taekyun Shin Kyoung-Kap Lee College of Veterinary Medicine Jeju National University Stem Cell Research Center RNL BIO Co.Ltd.

Mesenchymal stem cells have been previously shown to exert an immunomodulatory function. The present study sought to investigate the effects of multipotential human adipose tissue-derived mesenchymal stem cells （hAdMSCs） on disease progression and cytokine expression in Lewis rats with experimental autoimmune encephalomyelitis （EAE） induced by myelin basic protein. The duration of EAE paralysis in the group treated on day 7 posfimmunization with 5 × 10^6 hAdMSCs was significantly reduced compared with the vehicle-treated controls and the 1 x 106 hAdMSC- treated group. The duration of EAE paralysis in the groups treated with 5 × 10^6 hAdMSCs on both day 1 and day 7 postimmunization was significantly reduced compared with the vehicle-treated controls and the groups treated with 5 × 10^6 hAdMSCs on both day 7 and day 10 postimmunization. The mRNA expression of interleukin-10 and indoleamine 2, 3-dioxygenase was significantly decreased in the hAdMSC-treated group compared with the vehicle-treated group. These findings suggest that the ameliorative effects of hAdMSCs on EAE symptoms operate in a dose- and time-dependent manner and can be mediated in part by the ample production of anti-inflammatory cytokines.

关键词： experimental autoimmune encephalomyelitis human adipose tissue mesenchymal stem cells intedeukin-10 interferon-gamma indoleamine 2, 3-dioxygenase neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effectiveness of menstruation hygiene skills training for adolescents with autism

引用

World Journal of Psychiatry 2023年第11期13卷 958-966页

作者： Meltem Kaydırak Büşra Yılmaz Merve Azak Çiğdem Bilge Department of Women Health and Gynecologic Nursing Istanbul University-CerrahpaşaFlorence Nightingale Faculty of NursingIstanbul 34381Türkiye Department of Pediatric Nursing Istanbul University-CerrahpaşaFlorence Nightingale Faculty of NursingIstanbul 34381Türkiye Department of Obstetrics and Women's Health Nursing Muğla SıtkıKoçman UniversityFaculty of Health SciencesMuğla 48000Türkiye

BACKGROUND Adolescents with autism spectrum disorder(ASD)may encounter many difficulties with their menstrual *** challenges that adolescents with ASD may face include understanding physical changes,coping with symptoms,emotional sensitivity,communication,personal care,and *** To evaluate the effect of menstrual hygiene skills training given to adolescents with ASD on their menstrual hygiene *** The study was conducted with 15 adolescents diagnosed with ASD by the single group pre-test and post-test model in three special education centers in Tü*** were collected with the Adolescent and Parent Information Form and the Adolescent-Specific Menstrual Hygiene Skill Registration *** While the mean age of adolescents was 16.06±0.88 years,the mean age of individuals responsible for adolescent care was 43.66±5.56 *** 60.0%of the adolescents noticed the onset of bleeding before training,this rate was 93.3%after *** Adolescent-Specific Menstrual Hygiene Skill Registration Form showed a statistically significant increase in the application steps after the *** difference between the menstrual hygiene skill scores of adolescents CONCLUSION The menstrual hygiene skills training given to adolescents with ASD was beneficial in increasing their menstrual hygiene *** individuals must take responsibility during menstruation and independently manage their continuous care activities.

关键词： Autism Adolescent Menstruation Hygiene Training

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Retinoic acid enhances lactoferrin-induced IgA responses by increasing betaglycan expression

引用

Cellular & Molecular Immunology 2016年第6期13卷 862-870页

作者： Jeong-Min Lee Young-Saeng Jang Bo-ra Jin Sun-Jin Kim Hyeon-Jin Kim Bo-Eun Kwon Hyun-Jeong ko Sung-il Yoon Geun-Shik Lee Woan-Sub Kim Goo-Young Seo Pyeung-Hyeun Kim Department of Molecular Bioscience School of Biomedical Science Kangwon National University Chuncheon Republic of Korea Laboratory of Microbiology and Immunology College of Pharmacy Kangwon National University Chuncheon Republic of Korea Department of Systems Immunology College of Biomedical Science Kangwon National University Chuncheon 200-701 Republic of Korea College of Veterinary Medicine Kangwon National University Chuncheon Gangwon 200-701 Republic of Korea Department of Animal Life and Environmental Science College of Agriculture and Life Science Hankyong National University Anseong-si 456-749 Republic of Korea

Lactoferrin （LF） and retinoic acid （ra） are enriched in colostrum, milk, and mucosal tissues. We recently showed that LF-induced IgA class switching through binding to betaglycan （transforming growth factor-beta receptor III, TpRIII） and activation of canonical TGF-p signaling. We investigated the combined effect of LF and ra on the overall IgA response. An increase in IgA production by LF was further augmented by ra. This combination effect was also evident in Ig germ-line α （GLa） transcription and GLa promoter activity, indicating that LF in cooperation with ra increased IgA isotype switching. We subsequently found that ra enhanced TβRIII expression and that this increase contributed to LF-stimulated IgA production. In addition to the IgA response, LF and ra in combination also enhanced the expression of the gut-homing molecules C-C chemokine receptor 9 （CCR9） and a4β7 on B cells. Finally, peroral administration of LF and ra enhanced the frequency of CCR9＋ IgA＋ plasma cells in the lamina propria. Taken together, these results suggest that LF in cooperation with ra can contribute to the establishment of gut IgA responses.

关键词： gut homing molecule IgA lactoferrin retinoic acid TGF-β receptor

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

斯洛伐克西喀尔巴阡山脉内侧Veporicum地区的地球动力学演化序列与菱镁矿和滑石矿床成因(英文)

引用

岩石学报 2004年第4期20卷 837-854页

作者： Zoltán NMETH Walter PROCHASKA Martin raDVANEC Martin koV■IK Ján MADAraS Peter koD■ra L'ubomír Hra■ko Geological Survey of Slovak Republic Jesenskeho 8 SK-040 01 Kosice Slovak RepublicDepartment of Geological Sciences University of Leoben A-8700 Leoben AustriaGeological Survey of Slovak Republic Marku ovsk cesta 1 SK-052 01 Spisska Nova Ves Slovak RepublicGeological Survey of Slovak Republic Mlynsk dolina 1 SK-817 04 Bratislava Slovak RepublicGeological Survey of Slovak Republic Mlynsk dolina 1 SK-817 04 Bratislava Slovak RepublicGeological Survey of Slovak Republic Mlynsk dolina 1 SK-817 04 Bratislava Slovak RepublicGeological Survey of Slovak Republic Mlynsk dolina 1 SK-817 04 Bratislava Slovak Republic

本文总结并报导了斯洛伐克西喀尔巴阡山脉内侧的石炭纪岩石中产出的菱镁矿和滑石成因的最新资料.这些矿床赋存于Veporicum构造超单元中和该超单元与Gemericum的接触带中.北部Sinec成矿带是主要的菱镁矿和滑石矿化区,产出的主要矿床有kok... 详细信息

本文总结并报导了斯洛伐克西喀尔巴阡山脉内侧的石炭纪岩石中产出的菱镁矿和滑石成因的最新资料.这些矿床赋存于Veporicum构造超单元中和该超单元与Gemericum的接触带中.北部Sinec成矿带是主要的菱镁矿和滑石矿化区,产出的主要矿床有kokava,Sinec,Samo,Hnsta-Mutnik等矿床.而南部的Ochtina成矿带只产有菱镁矿床,主要矿床包括在Dubrava地体上的Dubrava,Mikov?JedL'vec;Luben韐,Ochtina,kosice-Bankov,Banisko,Medvedia等矿床.菱镁矿形成于变质M1期石炭系中方解石被白云石和菱镁矿连续交代过程(北矿带成矿温度为280～400℃,南矿带成矿温度为370～420℃;radvanec＆Prochska,2001;kodera＆radvanec,2002).Permoscythian蒸发卤水提供了Mg.成矿事件和华力西期碰撞后运动有关.拉伸构造和高热流值促使成矿热液系统的产生.滑石矿化则形成于稍晚的不同期变质事件(M2),成矿流体来源也与菱镁矿化不同.构造的、微构造的、变质的以及地质年代学的数据将滑石成矿作用和阿尔卑斯上白垩系的构造地热事件AD2联系在一起.AD2事件是阿尔卑斯碰撞(AD1)地壳加厚和变质核杂岩体起源的结果,体现在地壳不整合面上的区域拉伸,及开放系统中大规模热液流动.这一过程在更靠近Veporic热穹的北带区域(Sinec剪切带)很显著,而向着Veporic热穹的周围部分(南Ochtina带),M2变质过程和块滑石化则逐渐减弱.Sinec剪切带是北Sinec带中突出的AD2-AD3结构,白云石/菱镁矿透镜体(在M1期交代造成的)和相伴随的岩石夹杂在AD1中更坚硬的基底岩石之中.本研究证明了AD2中块滑石化的普遍性,滑石和白云石2形成于拉伸显微构造中(变质过程M2;温度为490～540℃,压力为240～330MPa).在Sinec带中AD3阶段的对偶剪切作用形成了该带中的滑石矿.它是AD2事件从去顶到区域扭压剪切的动力学转变过程的逐步延续.北Sinec带使AD3变形处于由坚硬岩石包围的软岩石的狭窄的剪切带中,而在南Ochtina带中AD3变形产生在由里面漂浮着坚硬碳酸盐块的软的岩石柱中.在Ochtina带中,在AD2和AD3阶段由于M2期较低的P-T条件和变形梯度导致了该区有经济价值的滑石矿化不发育.总之,现有的研究结果能用作阿尔卑斯型地体中菱镁矿和滑石找矿的基本标志.

关键词：菱镁矿和滑石成因地球动力学演化剪切带显微结构流体包裹西喀尔巴阡山脉

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Base4Work共享办公空间

引用

现代装饰 2022年第4期 14-23页

作者： Ján Antal Martin Stára Barbora S.Babocká(Studio Perspektiv) Martin Paško(DF Creative Group) 范嘉苑(编译) BoysPlayNice(摄影) 不详

在斯洛伐克的首都布拉迪斯拉发,只有少数的工业遗迹能适应当下需求,由建筑师Jurkovic设计的著名供热厂就是其中之一。这座功能主义建筑在经过为期三年的改造后,已作为一个现代共享办公空间面向公众开放。该项目由StudioPerspektiv担纲... 详细信息

在斯洛伐克的首都布拉迪斯拉发,只有少数的工业遗迹能适应当下需求,由建筑师Jurkovic设计的著名供热厂就是其中之一。这座功能主义建筑在经过为期三年的改造后,已作为一个现代共享办公空间面向公众开放。该项目由StudioPerspektiv担纲室内设计,DFCreative Group负责内部空间的新结构建造方案,而建筑围护结构的翻新工作则由专门从事历史建筑保护与改造的PAMARCH公司负责监管。

关键词：工业遗迹建筑围护结构室内设计共享办公历史建筑保护供热厂布拉迪斯拉发建造方案

来源：

维普期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

氨己烯酸治疗婴儿痉挛的疗效和安全性观察

引用

儿科药学杂志 2018年第7期24卷 6-9页

作者：南在元赵敏廷 A-ra ko 姜薰澈哈尔滨市儿童医院、哈尔滨医科大学附属第二医院黑龙江哈尔滨150010 韩国延世大学医学院 Severance儿童医院韩国

目的:评价氨己烯酸治疗婴儿痉挛的疗效和安全性。方法:选择2015年4月至2016年9月于韩国Severance儿童医院诊治的46例婴儿痉挛患者给予口服氨己烯酸治疗,起始剂量为50 mg/(kg·d),第2天加至100 mg/(kg·d),如症状控制明显,则继续应用3~6... 详细信息

目的:评价氨己烯酸治疗婴儿痉挛的疗效和安全性。方法:选择2015年4月至2016年9月于韩国Severance儿童医院诊治的46例婴儿痉挛患者给予口服氨己烯酸治疗,起始剂量为50 mg/(kg·d),第2天加至100 mg/(kg·d),如症状控制明显,则继续应用3~6个月,定期复查脑电图;如1周后无效,则加量至150 mg/(kg·d),应用3~6个月,随访时间为3~10个月。结果:氨己烯酸单药治疗总有效率为67.4%(31/46),无发作率为19.6%(9/46),复发率6.5%(3/46),短期不良反应主要为嗜睡、纳差、激惹、多动。结论:氨己烯酸治疗婴儿痉挛症效果显著,复发率低,不良反应通常在早期出现。

关键词：婴儿痉挛氨己烯酸疗效安全性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pharmacological Investigation of “Meridian Tropism” in Three “Shen” Chinese Herbs

引用

Chinese Medicine 2019年第4期10卷 121-135页

作者： Pou-Kuan Leong Hoi-Yan Leung Wing-Man Chan Kam-Ming ko Division of Life Science Hong Kong University of Science & Technology Clear Water Bay Hong Kong SAR China

“Meridian tropism” refers to the organ-specific biological action(s) produced by a Chinese herb following its oral administration, which is analogous to the concept of “bioavailability” in Western medicine. In this study, we compared the in vitro and ex vivo pharmacological actions of three herbs [namely, Dangshen (DS, Codonopsis radix), ranshen (RS, Ginseng radix) and Xiyangshen (XYS, Panacis Qinquifolii ra-dix)] to validate their meridian tropism. We compared the in vitro and ex vivo pharmacological actions [i.e. the ability to increase splenocyte proliferation and adenosine triphosphate-generation capacity (ATP-GC)] of the ethanolic extracts of DS, RS and XYS to validate their meridian tropism. Results showed that DS, RS and XYS (at 30 - 300 μg/mL) can both stimulate the proliferation of primary mouse splenocytes in vitro and increase adenosine triphosphate-generation capacity (ATP-GC) in cultured Caco 2 colon epithelial cells in vitro. Interestingly, oral administration of DS and RS (but not XYS, at 3 and 6 g/kg/day × 3 consecutive days) was found to stimulate the proliferation of splenocytes ex vivo at 24 h post-treatment in mice. Similarly, DS and RS (but not XYS) increased the ATP-GC of mitochondrial fractions isolated from a small segment of mouse intestine at 48 h post-treatment. This observation is consistent with the meridian tropism of the pharmacological action of “Shen”, i.e., the accessibility of DS and RS (but not XYS) to the “Spleen” meridian. The comparison between the results obtained from in vitro and in vivo/ex vivo bioassays may offer a potential method for assessing meridian tropism in Chinese herbs.

关键词： Codonopsis radix Ginseng radix Panacis Qinquifolii radix ATP-Generation Capacity Splenocyte Proliferation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

关于Jesmanowicz的猜测

引用

四川大学学报(自然科学版) 1958年第2期 81-90页

作者：柯召

***①曾提出猜测(H)对于正整数a,b,c,x,y,z,如果有a~2+b~2=c~2和a~x+b~y=c~z,那末x=y=z=2.对于下整数a=2n+1, b=2n(n+1), c=2n(n+1)+1, (1)Sierpinski②和Jesmanowicz①已经证明猜测(H)在n=1,2,3,4,5时都能成立,

关键词：正整数解大学学报四川原根定理 Jesmanowicz

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Efficacy of endoscopic ultrasonography-guided fine needle aspiration for pancreatic neuroendocrine tumor grading

引用

World Journal of Gastroenterology 2015年第26期21卷 8118-8124页

作者： Mitsuru Sugimoto Tadayuki Takagi Takuto Hikichi Rei Suzuki ko Watanabe Jun Nakamura Hitomi Kikuchi Naoki konno Yuichi Waragai Hiroyuki Asama Mika Takasumi Hiroshi Watanabe Katsutoshi Obara Hiromasa Ohira Department of Gastroenterology and Rheumatology Fukushima Medical UniversitySchool of Medicine Department of Endoscopy Fukushima Medical University Hospital

AIM: To evaluate the efficacy of endoscopic ultrasonography-guided fine needle aspiration(EUS-FNA) for grading pancreatic neuroendocrine tumors(PNETs).METHODS: A total of 22 patients were diagnosed with PNET by EUS-FNA between October 2001 and December 2013 at Fukushima Medical University *** these cases,we targeted 10 PNET patients who were evaluated according to the World Health Organization(WHO) 2010 *** was performed in eight patients,and chemotherapy was performed in two patients due to multiple liver *** obtained by EUS-FNA were first stained with hematoxylin and eosin and then stained with chromogranin,synaptophysin,CD56,and *** specimens were graded by the Ki-67 index according to the WHO 2010 *** obtained by surgery were graded by the Ki-67 indexand mitotic count(WHO 2010 classification).For the eight specimens obtained by EUS-FNA,the Ki-67 index results were compared with those obtained by *** the two cases treated with chemotherapy,the effects and prognoses were ***: The sampling rate for histological diagnosis by EUS-FNA was 100%.No adverse effects were *** concordance rate between specimens obtained by EUS-FNA and surgery was 87.5%(7/8).Fo r t h e t w o c a s e s t re a t e d w i t h c h e m o t h e ra p y,case 1 received somatostatin analog therapy and transcatheter arterial infusion(TAI) targeting multiple liver *** treatment consisted of *** chemotherapy,the primary tumor remained unconfirmed,although the multiple liver metastases diminished *** 2 was classified as neuroendocrine carcinoma(NEC) according to the Ki-67 index of a specimen obtained by EUS-FNA; therefore,cisplatin and irinotecan therapy was ***,severe adverse effects,including renal failure and diarrhea,were observed,and the therapy regimen was changed to cisplatin and *** targeting multiple liver metastases was perfor

关键词： Pancreatic neuroendocrine tumor Endoscopicultrasonography-guided fine needle aspiration Ki-67index World Health Organization classification 2010 Chemotherapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：