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Ultrastructural changes in porcine liver sinusoidal endothelial cells of machine perfused liver donated after cardiac death

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World Journal of Gastroenterology 2022年第19期28卷 2100-2111页

作者： Hiroki Bochimoto Yo Ishihara Nur Khatijah Mohd Zin Hiroyoshi Iwata Daisuke Kondoh Hiromichi Obara naoto matsuno Department of Cell Physiology The Jikei University School of MedicineMinato-ku 105-8461TokyoJapan Department of Transplantation Technology and Therapeutic Development Asahikawa Medical UniversityAsahikawa 078-8510HokkaidoJapan Department of Surgery Asahikawa Medical UniversityAsahikawa 078-8510HokkaidoJapan Laboratory of Veterinary Anatomy Obihiro University of Agriculture and Veterinary MedicineObihiro 080-8555HokkaidoJapan Department of Mechanical Engineering Tokyo Metropolitan UniversityHachioji 192-0397TokyoJapan

BACKGROUND The machine perfusion(MP)preservation including hypothermic MP(HMP)and midthermic MP(MMP)has been considered as a promising strategy to preserve the functions of liver donated after cardiac *** importance of understanding liver sinusoidal endothelial cells(LSEC)damage in regulating liver injury during MP has been ***,the ultrastructural changes in the LSEC and sinusoids around them after MP are *** To investigate the ultrastructural changes in the LSEC and sinusoids around them after *** Porcine liver grafts undergo a warm ischemia time of 60 minutes perfused for 4 h with modified University of Wisconsin gluconate *** A grafts were preserved with HMP at 8℃ constantly for 4 *** B grafts were preserved with a rewarming solution at 22℃ by MMP for 4 *** the ultrastructural changes in the LSEC and sinusoids in Group A and B were comparatively analyzed by using osmium-maceration scanning electron microscopy with complementary transmission electron microscopy *** An analysis of the LSEC after warm ischemia revealed that mitochondria with condensed-shaped cristae,abnormal vesicles,reduction of ribosomes and the endoplasmic reticulum(ER)surround the mitochondria *** MP subsequent after warm ischemia alleviate the abnormal vesicles and reduction of ribosomes in LSEC,which indicated the reduction of the ER ***,MMP could restore the tubular mitochondrial cristae,while after HMP the condensed and narrow mitochondrial cristae *** addition,the volume of the sinusoidal space in the liver grafts after MMP were restored,which indicated a lower risk of pressure injury than *** MMP alleviates the ER damage of LSEC by warm ischemia,additionally restore the metabolism of LSEC via the normalization of mitochondria and prevent the share stress damage of liver grafts.

关键词： Liver Sinusoidal endothelial cells Warm ischemia Machine perfusion preservation Transplantation Ultrastructure

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持续血液滤过及内毒素吸附治疗外科感染性多器官衰竭(英文)

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河南医科大学学报 2001年第3期36卷 312-314页

作者： naoto matsuno ToshiakiI keda Takeshi Nagao The Fifth Department of Surgery Hachioji Medical Center of Tokyo Medical University1163Tate-machiHachioji-cityTokyo1930998Japan Division of Critical Care Medicine Hachioji Medical Center of Tokyo Medical University1163TatemachiHachiojicityTokyo1930

目的 :探索持续血液滤过及内毒素直接吸附治疗外科感染性多器官衰竭的有效性。方法 :为 1例外科感染性多器官衰竭患者进行血液持续滤过 ,并利用多粘菌素B结合纤维 (PMX)进行内毒素吸附。PMX治疗每 2 /d ,共 8d。结果 :用上述方法治疗后 ... 详细信息

目的 :探索持续血液滤过及内毒素直接吸附治疗外科感染性多器官衰竭的有效性。方法 :为 1例外科感染性多器官衰竭患者进行血液持续滤过 ,并利用多粘菌素B结合纤维 (PMX)进行内毒素吸附。PMX治疗每 2 /d ,共 8d。结果 :用上述方法治疗后 ,内毒素和IL 6水平下降 ,病情好转并停用血管活性药物。结论 :持续血液滤过并用PMX吸附内毒素是治疗外科感染性多器官衰竭的有效方法。

关键词：多粘菌素B结合纤维内毒素血液滤过多器官衰竭外科感染

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Algorithm Selection Method Based on Coupling Strength for Partitioned Analysis of Structure-Piezoelectric-Circuit Coupling

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1237-1258页

作者： Daisuke Ishihara naoto Takayama Department of Intelligent and Control Systems Kyushu Institute of TechnologyIizuka820-8502Japan

In this study, we propose an algorithm selection method based on coupling strength for the partitioned analysis ofstructure-piezoelectric-circuit coupling, which includes two types of coupling or inverse and direct piezoelectriccoupling and direct piezoelectric and circuit coupling. In the proposed method, implicit and explicit formulationsare used for strong and weak coupling, respectively. Three feasible partitioned algorithms are generated, namely(1) a strongly coupled algorithm that uses a fully implicit formulation for both types of coupling, (2) a weaklycoupled algorithm that uses a fully explicit formulation for both types of coupling, and (3) a partially stronglycoupled and partially weakly coupled algorithm that uses an implicit formulation and an explicit formulation forthe two types of coupling, *** examples using a piezoelectric energy harvester,which is a typicalstructure-piezoelectric-circuit coupling problem, demonstrate that the proposed method selects the most costeffectivealgorithm.

关键词： Multiphysics coupling strength partitioned algorithm structure-piezoelectric-circuit coupling strongly coupled algorithm weakly coupled algorithm

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Hybrid Strategy of Partitioned and Monolithic Methods for Solving Strongly Coupled Analysis of Inverse and Direct Piezoelectric and Circuit Coupling

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1371-1386页

作者： Daisuke Ishihara Syunnosuke Nozaki Tomoya Niho naoto Takayama Department of Intelligent and Control Systems Kyushu Institute of TechnologyFukuokaJapan

The inverse and direct piezoelectric and circuit coupling are widely observed in advanced electro-mechanical systems such as piezoelectric energy *** strongly coupled analysis methods based on direct numerical modeling for this phenomenon can be classified into partitioned or monolithic *** formulation has its advantages and disadvantages,and the choice depends on the characteristics of each coupled *** study proposes a new option:a coupled analysis strategy that combines the best features of the existing formulations,namely,the hybrid partitioned-monolithic *** analysis of inverse piezoelectricity and the monolithic analysis of direct piezoelectric and circuit interaction are strongly coupled using a partitioned iterative hierarchical *** a typical benchmark problem of a piezoelectric energy harvester,this research compares the results from the proposed method to those from the conventional strongly coupled partitioned iterative method,discussing the accuracy,stability,and computational *** proposed hybrid concept is effective for coupled multi-physics problems,including various coupling conditions.

关键词： Structure-piezoelectric-circuit interaction energy harvesting partitioned method monolithic method hybrid method

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Natural Convection Melting in a Rectangular Heat Storage Tank of Carbon Nanotube Dispersed Latent Heat Storage Material

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Journal of Thermal Science 2024年第3期33卷 847-855页

作者： Shin-ichi MORITA Tomoya SAITO Kazunori TAKAI Yasutaka HAYAMIZU naoto HARUKI Division of Mechanical and Electrical Engineering Kitami Institute of Technology165 Koen-choKitami-shiHokkaido090-8507Japan National Institute of Technology Yonago College4448 Hikona-cyoYonago-shiTottori683-8502Japan Okayama Prefectural University 111 KubokiSoja-shiOkayama719-1197Japan

A dispersion system fluid can convect even if the dispersoid is a solid ***,heat exchange performance can be improved while maintaining fluidity using a material with high thermal conductivity as the *** study presents the melting performance evaluation results of a latent heat storage material with a carbon nanotube(CNT)dispersion system with high thermal conductivity,which enhances the thermal conductivity of the latent heat storage material and does not limit free *** the thermal conductivity and enhancing the melting convection of the heat storage material result in increased latent heat storage *** this study,the thermal conductivity of the latent heat storage material was successfully increased by dispersing CNTs in the *** 0.1%(in mass)of multi-wall CNT(MWCNT)was dispersed in a paraffin-based latent heat storage material,the shear stress increased by 1.5 times at a shear rate of 500 s^(-1),while taking into account the potential effects of convective ***,a latent heat storage experiment was conducted in a rectangular heat storage tank using the CNT dispersion composition ratio as a parameter.A rectangular vessel with a heated vertical surface was used for the latent heat storage *** melting speed was determined by comparing the amount of latent heat stored in a CNT-dispersed latent heat storage material and a single-phase latent heat storage material *** experimental results show that the time required for the latent heat storage material to completely melt in the heat storage tank was the shortest for the single-phase latent heat storage material ***,the fastest melting progress was observed for the sample with 0.02%(in mass)MWCNT content in the melting rate range of up to approximately 40%in the *** results indicate that this phenomenon is caused by the difference in the melting rates in the upper part of the *** generated data are useful for det

关键词： latent heat storage phase change carbon nano tube free convection heat transfer

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电子非厄米系统中的拓扑自旋图样

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Science Bulletin 2024年第9期69卷 325-333页

作者：张骁骁 naoto Nagaosa RIKEN Center for Emergent Matter Science(CEMS) WakoSaitama 351-0198Japan Department of Applied Physics University of TokyoTokyo 113-8656Japan

Non-Hermitian systems have been discussed mostly in the context of open systems and *** experimental progress is much from optical,cold-atomic,and classical platforms due to the vast tunability and clear identification of ***,their counterpart in solid-state electronic systems in equilibrium remains unmasked although highly desired,where a variety of materials are available,calculations are solidly founded,and accurate spectroscopic techniques can be *** demonstrate that,in the surface state of a topological insulator with spin-dependent relaxation due to magnetic impurities,highly nontrivial topological soliton spin textures appear in momentum *** spin-channel phenomena are delicately related to the type of non-Hermiticity and correctly reveal the most robust non-Hermitian features detectable ***,the distinct topological soliton objects can be deformed to each other,mediated by topological transitions driven by tuning across a critical direction of doped *** results not only open a solid-state avenue to exotic spin patterns via spin-and angle-resolved photoemission spectroscopy,but also inspire non-Hermitian dissipation engineering of spins in solids.

关键词： Non-Hermitian system Topological spin texture Magnetic impurity Surface state ARPES

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电子非厄米系统中的拓扑自旋图样（英文）

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Science Bulletin 2024年第3期 325-333页

作者：张骁骁 naoto Nagaosa RIKEN Center for Emergent Matter Science (CEMS) Department of Applied Physics University of Tokyo

Non-Hermitian systems have been discussed mostly in the context of open systems and *** experimental progress is much from optical, cold-atomic, and classical platforms due to the vast tunability and clear identification of observables. However, their counterpart in solid-state electronic systems in equilibrium remains unmasked although highly desired, where a variety of materials are available, calculations are solidly founded, and accurate spectroscopic techniques can be applied. We demonstrate that, in the surface state of a topological insulator with spin-dependent relaxation due to magnetic impurities, highly nontrivial topological soliton spin textures appear in momentum *** spin-channel phenomena are delicately related to the type of non-Hermiticity and correctly reveal the most robust non-Hermitian features detectable spectroscopically. Moreover, the distinct topological soliton objects can be deformed to each other, mediated by topological transitions driven by tuning across a critical direction of doped magnetism. These results not only open a solid-state avenue to exotic spin patterns via spin-and angle-resolved photoemission spectroscopy, but also inspire non-Hermitian dissipation engineering of spins in solids.

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公共空间公共性的理论研究与分析框架构建

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国际城市规划 2024年第3期39卷 82-90页

作者：蒋敏中岛直人卢峰重庆大学建筑城规学院东京大学工学部都市工学系

当前公共空间建设、管理和运营过程中日益多样的参与主体和灵活的合作模式拓展了公共空间的内涵与边界,这种转变带来一种区别于公私二元对立的新视角。在这样的背景下,将公共性视为一种价值和愿景而非“私”的对立面,从更本质的角度理... 详细信息

当前公共空间建设、管理和运营过程中日益多样的参与主体和灵活的合作模式拓展了公共空间的内涵与边界,这种转变带来一种区别于公私二元对立的新视角。在这样的背景下,将公共性视为一种价值和愿景而非“私”的对立面,从更本质的角度理解公共性的内涵有助于为复杂的利益博弈和权利平衡提供一种价值参照。本文通过研究西方代表性文献,分析了公私二元对立关系的瓦解过程,将公共性的核心价值总结为公开性、异质性和共同性,进而分析了公共空间公共性的价值。在此基础上,受现象学和新行为主义心理学的启发,本文提出将公共空间公共性视为一种主观感知的研究思路,继而融合公共空间的客观特征和使用人群的主观感知构建了一种新的公共空间公共性分析框架,规避了公私的二元对立,实现了评价主体的转变,且有助于反映文脉特征和地域差异,为公共空间公共性的定量研究和机制探索提供新的思路。

关键词：公共空间公共性理论研究公共性感知分析框架

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Loess magnetic properties in the Ili Basin and their correlation with the Chinese Loess Plateau

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Science China Earth Sciences 2010年第3期53卷 419-431页

作者： naoto Ishikawa Graduate School of Human and Environmental Studies Kyoto University

Over the past two decades, magnetoclimatological studies of loess-paleosol sequences in the Chinese Loess Plateau (CLP) have made outstanding achievements, which greatly promote the understanding of East Asian paleomonsoon evolution, inland aridification of Asia, and past global climate changes. Loess magnetic properties of the CLP have been well studied. In contrast, loess magnetic properties from outside the CLP in China have not been fully understood. We have little knowledge about the magnetic properties of loess in the Ili Basin, an intermontane depression of the Tianshan (or Tien Shan) Mountains. Here, we present the results of rock magnetic measurements of the Ili loess including mass magnetic susceptibility (χ) and anhysteretic remanent magnetization (ARM), high/low temperature dependence of susceptibility (TDS) and hysteresis, as well as X-ray diffraction (XRD) for mineral analysis. Based on the comparison with loess-paleosol sequences in the CLP (hereafter referred to as the Chinese loess), we discuss the possible magnetic susceptibility enhancement mechanism of the Ili loess. The results show that 1) the total magnetic mineral concentration of the Ili loess is far lower than that of the Chinese loess, though they have similar magnetic mineral compositions. The ferrimagnetic minerals in the Ili loess are magnetite and maghemite, and the antiferromagnetic mineral is hematite; XRD analysis also identifies the presence of ilmenite. The ratio of maghemite is lower in the Ili loess than in the Chinese loess, but the ratios of magnetite and hematite are higher in the Ili loess than in the Chinese loess. 2) The granularity of magnetic minerals in the Ili loess, dominated by pseudo-single domain (PSD) and multi-domain (MD) grains, is generally much coarser than that of the Chinese loess. Ultrafine pedogenically-produced magnetic grains have a very limited contribution to the susceptibility enhancement. Rather, PSD and MD particles of magnetite and maghemite are th

关键词： loess magnetic property magnetic susceptibility the Ili Basin the Chinese Loess Plateau

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Estimating camera parameters from starry night photographs

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Computational Visual Media 2020年第4期6卷 445-454页

作者： naoto Ishikawa Yoshinori Dobashi Graduate School of Information Science and Technology Hokkaido UniversitySapporoJapan

We propose an efficient, specific method for estimating camera parameters from a single starry night image. Such an image consists of a collection of disks representing stars, so traditional estimation methods for common pictures do not work. Our method uses a database, a star catalog, that stores the positions of stars on the celestial sphere. Our method computes magnitudes(i.e., brightnesses) of stars in the input image and uses them to find the corresponding stars in the star catalog. Camera parameters can then be estimated by a simple geometric calculation. Our method is over ten times faster and more accurate than a previous method.

关键词： astrophotography constellation star identification pattern matching

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