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Temperature and Sound Survey on Steep Tea Farm Area and Salt Pan Site

Journal of Geological Resource and Engineering 2018年第1期6卷 37-44页

作者： naomi ando River Basin Control Bureau Technology Office Kotanabe 610-0311 Japan

Wazuka town in Kyoto prefecture has the largest farmland for Uji green tea on the steep hillsides. In 1953, this area suffered from flood disaster due to the heavy rainfall along with the valley wind. In this area, diluvia, Osaka strata and granite are outcropped along the Wazuka fault, and many old landslides in small scale could be identified. The River Basin Control Bureau has an experimental site locating on Ishidera area in Wazuka, where there was a house that was built about 150 years ago, and the habitants migrated after the 1953 flood. This area was developed for lots and housing during the economic bubble years around 1990, but was abandoned due to the occurrence of a small landslide and the inclination of concrete wall. To understand the distribution of ground water streams, 1 m-depth-ground temperature survey method and sound survey method were used. Using these methods, ground water streams were detected at the Kizu river bank gate site, at salt pan site gate trail, and on Ishidera landslide observatory. Based on the survey results, the construction sites of the wells for the drainage, steel-sheet piles for the river bank and watergate trails for the salt field area were suggested.

关键词： Ground water streams 1 m-depth-ground temperature sound survey tea farmland small landslide salt field watergatetrails.

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Clinical characteristics of gastrointestinal immune-related adverse events of immune checkpoint inhibitors and their association with survival

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World Journal of Gastroenterology 2021年第41期27卷 7190-7206页

作者： Kentaro Yamada Tsunaki Sawada Masanao Nakamura Takeshi Yamamura Keiko Maeda Eri Ishikawa Tadashi Iida Yasuyuki Mizutani naomi Kakushima Takuya Ishikawa Kazuhiro Furukawa Eizaburo Ohno Takashi Honda Hiroki Kawashima Masatoshi Ishigami Satoshi Furune Tetsunari Hase Kenji Yokota Osamu Maeda Naozumi Hashimoto Masashi Akiyama Yuichi ando Mitsuhiro Fujishiro Department of Gastroenterology and Hepatology Nagoya University Graduate School of MedicineNagoya City 4668560AichiJapan Department of Endoscopy Nagoya University HospitalNagoya City 4668560AichiJapan Department of Clinical Oncology and Chemotherapy Nagoya University HospitalNagoya City 4668560AichiJapan Department of Respiratory Medicine Nagoya University Graduate School of MedicineNagoya City 4668560AichiJapan Department of Dermatology Nagoya University Graduate School of MedicineNagoya City 4668560AichiJapan Department of Gastroenterology and Hepatology Graduate School of MedicineThe University of TokyoTokyo 1138655Japan

BACKGROUND Despite the popularity of immune checkpoint inhibitors(ICIs)in the treatment of advanced cancer,patients often develop gastrointestinal(GI)and non-GI immune-related adverse events(irAEs).The clinical characteristics and survival outcomes of GI-irAEs have not been fully elucidated in previous *** necessitates the evaluation of the impact of GI-irAEs on patients receiving ICI *** To evaluate the clinical characteristics of GI-irAEs and their impact on survival in patients treated with *** In this single-center,retrospective,observational study,we reviewed the records of 661 patients who received ICIs for various cancers at Nagoya University Hospital from September 2014 to August *** analyzed the clinical characteristics of patients who received ICI *** also evaluated the correlation between GI-irAE development and prognosis in non-small cell lung cancer(LC)and malignant melanoma(MM).Kaplan-Meier analysis was used to compare the median overall survival(OS).Multivariate Cox proportional hazards models were used to identify prognostic factors.A P value<0.05 was considered statistically *** GI-irAEs occurred in 34 of 605 patients(5.6%)treated with an anti-programmed cell death-1/programmed death-ligand 1(anti-PD-1/PD-L1)antibody alone and in nine of 56 patients(16.1%)treated with an anti-cytotoxic T-lymphocyte antigen 4(CTLA-4)antibody alone or a combination of anti-PD-1 and anti-CTLA-4 *** cumulative incidence and median daily diarrhea frequency were significantly higher in patients receiving anti-CTLA-4 antibodies(P<0.05).In 130 patients with MM,OS was significantly prolonged in the group that continued ICI treatment despite the development of GI-irAEs compared to the group that did not experience GI-irAEs(P=0.035).In contrast,in 209 patients with non-small cell LC,there was no significant difference in OS between the *** multivariate analyses showed that a performance status of 2-3(ha

关键词： Colitis Cytotoxic T-lymphocyte antigen 4 Diarrhea Drug-related side effects and adverse reactions Immune checkpoint inhibitors Prognosis

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TOKYO 寻找设计新灵感

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明日风尚 2008年第7期 11-11页

作者： naomi Saeki Tadao ando Architect Associates’ Tokyu Corporation Kosuke Tamura

近年,东京不单潮流时服受欢迎,前卫家佩亦人气急孔"潮"店开了一间又一间,其中,荷兰名店Droog Design刚于六月在东京惠比寿登陆。Droog Design是以荷兰名设计师Gijs Bakker及设计评论家Renny Ramakers为主打的荷兰设计名牌,1993年开业以... 详细信息

近年,东京不单潮流时服受欢迎,前卫家佩亦人气急孔"潮"店开了一间又一间,其中,荷兰名店Droog Design刚于六月在东京惠比寿登陆。Droog Design是以荷兰名设计师Gijs Bakker及设计评论家Renny Ramakers为主打的荷兰设计名牌,1993年开业以来,其崭新及前卫的设计,于欧洲大受欢迎。

关键词： TOKYO 大都会博物馆

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TOKYO 环保太空船车站

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明日风尚 2008年第7期 11-11页

作者： naomi Saeki Tadao ando Architect Associates’ Tokyu Corporation Kosuke Tamura

连结琦玉县和光市的地下铁——东京地铁副都心线刚于6月14日开通,这条地铁线的话题之作是涉谷站(现在正建得如火如荼之中,这次展出是其中一部分,要观全貌,须等至二○一二年)。涉谷站的建造概念是"太空船",由日本炙手可热的顶级建筑师安... 详细信息

连结琦玉县和光市的地下铁——东京地铁副都心线刚于6月14日开通,这条地铁线的话题之作是涉谷站(现在正建得如火如荼之中,这次展出是其中一部分,要观全貌,须等至二○一二年)。涉谷站的建造概念是"太空船",由日本炙手可热的顶级建筑师安藤忠雄设计。地铁的车站,当然无法可以从外围观看,车站由一个整体直径约八十米、阔二十四米的椭圆形包着,沉降在地底。太空船的中央部分,有一个二十二米的巨大通风气孔,将月台和位于三楼的出闸大堂连结起来。

关键词： TOKYO 安藤忠雄地铁线副都等至舱底令人

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TOKYO 超级黄金地段菜园

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明日风尚 2008年第7期 11-11页

作者： naomi Saeki Tadao ando Architect Associates’ Tokyu Corporation Kosuke Tamura

东京寸金尺土,名店林立。但近日,竟然有贱价菜园出租。超平价菜园每块约八至十平方米,年租一万至一万二百日元,共有三幅,皆在繁华的涉谷车站附近。这是涉谷的自洽团体,利用废地开垦出来的,名为"区民菜园"。而且造福邻里,只租给区民。招... 详细信息

东京寸金尺土,名店林立。但近日,竟然有贱价菜园出租。超平价菜园每块约八至十平方米,年租一万至一万二百日元,共有三幅,皆在繁华的涉谷车站附近。这是涉谷的自洽团体,利用废地开垦出来的,名为"区民菜园"。而且造福邻里,只租给区民。招租消息一出干多名区民蜂拥而至,八十三块菜地要抽签公平租出。"我计划今年种枝豆和粟米。"六十岁的幸运租户三代齐出动,结果租得平地。

关键词： TOKYO 至一八至自洽寸金屈指一算

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