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亚麻纤维热解动力学的“model free”法和Coats-Redfern模型拟合法研究

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化工学报 2010年第9期61卷 2480-2487页

作者：许桂英 Watkinson A.Paul Ellis naoko 孙国刚中国石油大学(北京)重质油国家重点实验室北京102249 英属哥伦比亚大学生物与化工学院

亚麻纤维是一种潜在的气化原料,本文对亚麻纤维的热解行为进行了热重分析研究。10mg粒径为0.60~0.85mm的亚麻纤维颗粒在高纯氮气的保护下分别以10、20、30、***-1的升温速率线性升温到550℃。使用＂model free＂方法和Coats-Redfern模... 详细信息

亚麻纤维是一种潜在的气化原料,本文对亚麻纤维的热解行为进行了热重分析研究。10mg粒径为0.60~0.85mm的亚麻纤维颗粒在高纯氮气的保护下分别以10、20、30、***-1的升温速率线性升温到550℃。使用＂model free＂方法和Coats-Redfern模型拟合方法分析亚麻纤维的热解过程,并估算出热解反应的表观活化能。本文中＂model free＂方法包括Friedman、Flynn-wall-Ozawa、Vyazovkin and Wight三种等转化率方法及Kissinger法。三种等转化率方法均得到活化能随着转化率的升高而升高的规律。四种＂model free＂方法显示亚麻纤维的活化能主要在155~175kJ·mol-1之间,使用模型拟合方法所获得亚麻纤维热解反应的活化能值在175kJ·mol-1左右,使用模型拟合方法和＂model free＂方法所得的活化能值接近。这些活化能值可以为亚麻纤维高效的热化学利用提供基础数据。

关键词：等转化率法活化能 model free Coats-Redfern

Urban-Rural Comparison of HBV and HCV Infection Prevalence in Eastern China

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Biomedical and Environmental Sciences 2000年第4期13卷 243-253页

作者： QU JIANG-BIN ZHANG ZUO-WEN SHINICHIRO SHIMBO TAKAO WATANABE HARUO NAKATSUKA naoko MATSUDA-INOGUCHI KAE HIGASHIKAWA MASAYUKI IKEDA Department of Hygiene Faculty of Public HealthShandong Medical UniversityJinan 250012Shandong ProvinceChina Department of Food and Nutrition Kyoto Women’s UniversityKyoto 605-8501Japan Miyagi University of Education Senda 980-0845Japan Miyagi University Taiwa-cho 981-3298Japan Kyoto Industrial Health Association Kyoto 604-8472Japan

The present study was initiated to make an urban rural comparison of the prevalence of cases positive to hepatitis B and C virus (HBV and HCV, respectively) infection markers in densely populated eastern half of China. For this purpose, 10 survey sites were selected, i.e., six sites in urban areas (the city group; Beijing, Shanghai and four provincial capitals) and four sites in rural areas (the village group ; one village each in Jilin and Shandong Provinces, and two villages in Shaanxi Province). About 50 adult women per site volunteered to participate, from whom 494 valid blood samples were collected. Positivities to HBsAg (HBsAg +), anti HBs (anti HBs +) and anti HBc (anti HBc +) were examined by RIA methods, and that to anti HCV (anti HCV +) by either EIA or RIA. Those positive to any one of the three HBV infection markers were taken as HBV infection positive (HBV +). The prevalence of HBsAg +, HBV + and anti HBc + was 8%, 70% and 2.7% in the city group, and 8%, 65% and 2.0% in the village group, and no significant difference was found between the two groups. The overall prevalence was 8% for HBsAg +, 68% for HBV +, and 2.4% for anti HCV +. The results were discussed in reference to some 20 papers each on HBV + and anti HCV + prevalence in China published since 1991. The reviewing of these papers confirmed that the prevalence of HBV was high (i.e., in excess of 50%), whereas the prevalence of anti HCV was low (well below 5%), and that no substantial difference was found between the rural and urban populations.

关键词： HEPATITIS-C VIRUS HEPATOCELLULAR-CARCINOMA NUTRIENT INTAKE SOUTHERN CHINA ADULT WOMEN PROVINCE ANTIBODIES MARKERS

Evaluation of Oxidative Stress, Antioxidant Power, and Antioxidant Potential of Breastmilk of Breast-Feeding Mothers

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Health 2017年第8期9卷 1145-1158页

作者： naoko Kuramoto Mariko Kitagawa Department of Reproductive Health Nursing School of Nursing University of Human Environments Obu Japan Department of Reproductive Health Nursing Graduate School of Nursing Nagoya City University Nagoya Japan Department of Reproductive Health Nursing Graduate School of Nursing University of Human Environments Obu Japan

Purpose: The purpose of this study was to evaluate oxidative stress, antioxidant power, and antioxidant potential of breastmilk of breast-feeding mothers from the early postpartum period to the first 3 months postpartum, and to examine the dynamics and the relationships among them. Method: For 47 pu-erperant women who gave vaginal birth without any pregnancy complications, the oxidative stress levels (d-ROMs levels) and antioxidant power (BAP levels) in the maternal plasma as well as antioxidant potential of breastmilk (BAP levels in breastmilk) were measured 3 times, i.e., in the early puerperium (4 or 5 days after giving birth), one month after giving birth, and 3 months after giving birth. Results: The d-ROMs levels in the maternal plasma were significantly high in the early puerperium (p p p p p p < 0.05). Discussion: Regarding the oxidative stress and the antioxidant defense system of breast-feeding mothers, the d-ROMs level was highest and the BAP level was lowest in the early puerperium. The BAP level then showed a clear tendency to recover in the first 3 months after giving birth. Conclusion: When the maternal antioxidant potential remains at a low level after giving birth, careful consideration should be given to the mother’s health and wellbeing because there is a possibility that it might affect the antioxidant potential of breastmilk.

关键词： Oxidative Stress Antioxidant Power Maternal Plasma Breastmilk Postpartum

The relationship between tyrosine kinase inhibitor therapy and overall survival in patients with non-small cell lung cancer carrying EGFR mutations

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Chinese Journal of Cancer 2013年第3期32卷 136-140页

作者： Hidekazu Suzuki Tomonori Hirashima Norio Okamoto Tadahiro Yamadori Motohiro Tamiya naoko Morishita Takayuki Shiroyama Tomoyuki Otsuka Kanako Kitai Ichiro Kawase Department of Thoracic Malignancy Osaka Prefectural Medical Center for Respiratory and Allergic Diseases 3-7-1 Habikino Habikino-shiOsaka 583-8588 Japan.

For patients with epidermal growth factor receptor (EGFR) mutation-positive lung cancer, the relationship between the dose or duration of treatment with tyrosine kinase inhibitor (TKI) and overall survival remains unclear. Here, we analyzed clinical data of 39 patients who were diagnosed with EGFR mutation-positive non-small cell lung cancer and treated with TKI, but subsequently died. Several parameters were measured in this study: overall survival; first, second, and overall TKI therapy durations; first TKI intensity (actual dose/normal dose); and TKI rate (overall TKI therapy duration/overall survival). The response rate to TKI therapy was 50% , and the median survival was 553 days. After TKI therapy failed, 38.5% patients were re-challenged with TKI. We observed a moderate relationship [r = 0.534, 95% confidential interval (CI) = 0.263 to 0.727, P < 0.001] between overall TKI therapy duration and overall survival. However, we found no relationship between overall survival and first TKI intensity (r = 0.073, 95% CI = -0.380 to 0.247, P = 0.657) or TKI rate (r = 0.0345, 95% CI = -0.284 to 0.346, P = 0.835). Nonsmall cell lung cancer patients with mutation-positive tumors remained on TKI therapy for, on average, 33% of the overall survival time. These findings suggest that patients with EGFR mutation-positive tumors should not stick to using TKIs.

关键词：酪氨酸激酶抑制剂非小细胞肺癌治疗剂量肿瘤患者 EGFR 生存期突变表皮生长因子受体

Decrease in Serum Amyloid a Protein Levels Following Three-month Stays in Negatively Charged Particle-dominant Indoor Air Conditions

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Biomedical and Environmental Sciences 2018年第5期31卷 335-342页

作者： Suni Lee Shoko Yamamoto Yasumitsu Nishimura Hidenori Matsuzaki Kei Yoshitome Tamayo Hatayama Miho Ikeda YU Min Nagisa Sada naoko Kumagai-Takei Takemi Otsuki Department of Hygiene Kawasaki Medical School577 MastushimaKurashiki 701-0192Japan Department of Occupational and Environmental Health Science School of Public HealthSchool of Public HealthPeking University Health Science CenterBejing 100191China Department of Occupational Diseases Zhejiang Academy of Medical SciencesHangzhou 310013ZhejiangChina Department of Biophysical Chemistry Graduate School of MedicineDentistry and Pharmaceutical SciencesOkayama University1-1-1 TsushimanakaKita-KuOkayama 700-8530Japan

Objective The changes in serum adipokines and cytokines related to oxidative stress were examined during 3 months ‘Off to On’ and ‘On to Off’ periods using negatively charged particle-dominant indoor air conditions（NCPDIAC）.Methods Seven volunteers participated in the study,which included ‘OFF to 3 months ON’ periods（ON trials） for a total of 16 times,and ‘ON to 3 months OFF’（OFF trials） periods for a total of 13 *** With the exception of one case,serum amyloid A（SAA） levels decreased significantly during the ON *** Considering that SAA is an acute phase reactive protein such as C reactive protein（CRP）,this observed decrease might indicate the prevention of cardiovascular and atherosclerotic changes,since an increase in high-sensitive CRP is associated with the subsequent detection of these events.

关键词： Negatively charged particle Indoor air Serum amyloid A Biomarker Cardiovascular disease

Physical activity levels in American and Japanese men from the ERA-JUMP Study and associations with metabolic syndrome

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Journal of Sport and Health Science 2020年第2期9卷 170-178页

作者： naoko Sagawa Bonny Rockette-Wagner Koichiro Azuma Hirotsugu Ueshima Takashi Hisamatsu Tomoko Takamiya Aiman El-Saed Katsuyuki Miura Andrea Kriska Akira Sekikawa Department of Epidemiology Graduate School of Public HealthUniversity of PittsburghPittsburghPA 15261USA Institute for Integrated Sports Medicine School of MedicineKeio UniversityTokyo 160-8582Japan Department of Public Health Shiga University of Medical ScienceShiga 520-2192Japan Department of Environmental Medicine and Public Health Faculty of MedicineShimane UniversityShimane 693-0021Japan

Background:Metabolic syndrome(MetS) is a global health *** activity(PA) is a known modifiable risk factor for MetS and individual MetS ***,the role of PA could differ between sub-populations due to differences in the variability of PA and other MetS risk *** examine these differences,multi-country studies with standardized outcome measurement methods across cohorts are ***:Cross-sectional PA levels(total and domain specific) in healthy middle-aged(44-56 years) men in the Risk Factor Assessment among Japanese and *** in the Post-World War Ⅱ Birth Cohort(ERA-JUMP) Study(n=730;American:n=417;Japanese:n=313;from population-representative samples in Pittsburgh,Pennsylvania,USA,and Kusatsu,Shiga,Japan) were *** relationships between PA levels and MetS(overall and specific components) in/across the American and Japanese sub-cohorts(adjusting for age,smoking,and alcohol consumption)were also assessed using the same instruments(pedometer and validated questionnaire) to measure PA in both ***:A total of 510 individuals provided complete data on PA(American:n=265;Japanese:n=245).The American cohort had significantly lower mean±SD steps/day(7878±3399 steps/day) *** Japanese cohort(9055±3797 steps/day)(p <0.001) but had significantly higher self-reported moderate-vigorous leisure PA(American:15.9(7.4-30.3) metabolic task equivalent hours per week(MET-b/week) ***:4.0(0-11.3) METh/week,p <0.0001).In both sub-cohorts,each 1000 steps/day increase was associated with lower odds of having MetS(American:OR=0.90,95%CI:0.83-0.98;Japanese:OR=0.87,95%CI:0.79-0.95) and the individual MetS component of high waist circumference(American:OR=0.86,95%CI:0.79-0.94;Japanese:OR=0.87,95%CI:0.80-0.95).In the American cohort only,higher self-reported leisure PA(Met-b/week) was associated with lower odds of MetS and high waist circumference(OR=0.98,95%CI:0.97-0.99 for MetS and waist circumference,respectively).Conclusion:

关键词： Epidemiology Metabolic syndrome Pedometer Physical activity Questionnaire

Usefulness of Breast MRI for Safe Omission of Axillary Lymph Nodes Dissection in Sentinel Node-Positive Breast Cancer Patients

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Journal of Cancer Therapy 2017年第11期8卷 1049-1057页

作者： Hiromi Fuchikami naoko Takeda Kazuhiko Sato Department of Breast Oncology Tokyo-West Tokushukai Hospital Tokyo Japan

Background: Preoperative identification of patients with extensive lymph node metastasis (LNM) is important for safe omission of axillary lymph node dissection (ALND) in sentinel node (SN)-positive (SN+) breast cancer patients. Methods: We evaluated retrospectively the collected data of 758 breast cancer patients who underwent axillary surgery between 2008 and 2017, excluding those who received neoadjuvant chemotherapy. Results: Of the 758 patients, 607 were not suspicious to have LNM by axillary ultrasound (AUS-), but 38 suspicious cases were found by breast magnetic resonance imaging (MRI). Of 15 patients undergoing axillary fine needle biopsy (AFNA) due to second-look axillary ultrasound (AUS), 9 underwent ALND because of a positive AFNA (AFNA+). Among 81 (10.9%) patients undergoing ALND due to SN+ findings, 6 (7.4%) had extensive LNM (LNM ≥ 4). If MRI was not performed, among the 90 of 673 patients undergoing ALND who had SN+ findings, 12 (13.3%) had LNM ≥ 4. Conclusions: The proportion of cases with LNM ≥ 4 was reduced from 13.3% to 7.4% among patients undergoing SN biopsies combined with breast MRI. ALND might be omitted safely in SN+ cases according to detailed preoperative evaluations using additional breast MRI to ultrasound.

关键词： Breast Cancer Sentinel Node Axillary Lymph Node Dissection Breast MRI

Experimental observations of naturally occurring dust using a high-speed vacuum ultraviolet imaging system in EAST

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Plasma Science and Technology 2023年第5期25卷 1-7页

作者：侯善伟明廷凤石奇奇张文敏龙飞飞李邦邓荣婧庄清刘晓菊张凌提昂曾龙李国强 naoko ASHIKAWA Satoshi OHDACHI 高翔 Anhui University Hefei 230601People’s Republic of China Institute of Plasma Physics Chinese Academy of SciencesHefei 230031People’s Republic of China University of Science and Technology of China Hefei 230026People’s Republic of China Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Optoelectronic EngineeringShenzhen UniversityShenzhen 518060People’s Republic of China Hangzhou Dianzi University Hangzhou 310018People’s Republic of China National Institute for Fusion Sciences Toki 509-5292Japan SOKENDAI Toki 509-5292Japan

In the ELMy H-mode experiment,naturally occurring dust originating at the high-field side is clearly observed using the high-speed vacuum ultraviolet imaging system developed on the Experimental Advanced Superconducting Tokamak(EAST).The main ablation cloud shape is similar to the classical shape observed in pellet fueling ***,during the dust penetration,an erupted secondary cloudlet with a bent‘cigar’shape is observed and moves upwards along the direction perpendicular to the magnetic field line,which is different to the obviation in the pellet fueling *** may be due to the ion diamagnetic drift *** velocities of the secondary cloudlet are estimated to be 50–80 m s^(-1).In addition,a significant degradation of the plasma confinement is observed during the dust penetration.

关键词： H-mode HFS VUVI EAST tokamak dust cloudlet

Causal relationships between physical, mental and social health-related factors among the Japanese elderly: A chronological study

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Health 2012年第3期4卷 133-142页

作者： Motoyuki Yuasa Tanji Hoshi Takashi Hasegawa naoko Nakayama Toshihiko Takahashi Sugako Kurimori naoko Sakurai Graduate School of Medicine Juntendo University Tokyo Japan Graduate School of Nursing Ibaraki Christian University Ibaraki Japan Graduate School of Nursing Keio University Kanagawa Japan Graduate School of Urban System Science Tokyo Metropolitan University Tokyo Japan School of Nursing Tokyo Jikeikai Medical College Tokyo Japan

The World Health Organization defines health as a state of physical, mental and social well being. This study was conducted to explore chronological relationships between physical, mental and social factors. Among urban-dwelling elderly aged 65 years and over, data were collected via a self-report questionnaire in 2001 and 2004. The three health-related latent factors were identified with nine measurement variables by an exploratory factor analysis. A structural equation modeling method was used to analyze underlying relationships among the three factors with a cross-lagged model and a synchronous model. A total of 7,683 individuals aged between 65 and 84 years were analyzed. The three-year prior and current physical health significantly affected social health as well as mental health, and this effect appeared to be stronger in males compared to females. Maintenance of physical health may be crucial to support mental and social health among elderly individuals.

关键词： Physical Health Mental Health Social Health Elderly Japan