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The Application of an Improved Wavelet Threshold Function in De-noising of Heart Sound Signal

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The Application of an Improved Wavelet Threshold Function in...

Performance analysis and design of self-air-cooling reciprocating compressor’s cooling system

第32届中国控制与决策会议

作者： Zhang nannan College of Control Science and Engineering China University of Petroleum

ISBN: (数字)9781728158556

ISBN: (纸本)9781728158563

Heart sound can reflect the pathological characteristics of cardiovascular system.De-noising of heart sound is the basis of accurate identifying information.Wavelet transform is often used to de-noise heart sound signals.In this paper,by analyzing the advantages and disadvantages of traditional wavelet threshold and two improved threshold functions,a new two parameter adjustable wavelet threshold function is proposed.This function has a transition region which is more consistent with the continuous characteristics of the signal,and improves the signal integrity after de-noising.The experimental results show that the improved new function is better than the traditional wavelet threshold de-noising method in SNR and RMSE of heart sound signal,which has a certain practical value.

关键词： Heart sound signal de-noising Wavelet transform Threshold function

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Science China(Technological Sciences) 2020年第12期63卷 2631-2639页

作者： LIU YongGuang GAO XiaoHui CHENG nannan School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100191China

The cooling system,as an important part of high-pressure compressor,has always been a key technical bottleneck for its miniaturization. A new type self-air-cooling system is first proposed for the reciprocating compressor through ingenious structural design without any auxiliary equipment. The transient model of cooling system is established,which regards the cooling passage as a chamber with compressibility and heat exchange considering the linear and local flow resistance. The design principle is achieved by studying the working process and key parameters characteristics,which provides the theoretical foundation for the structural design. The experimental results show that the self-air-cooling system can quickly lower the temperature of the cylinder compared with natural cooling,which has considerable theoretical significance and practical value for the miniature high pressure compressor.

关键词： self-air-cooling reciprocating compressor design performance analysis

Sustainable development of electroencephalography materials and technology

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SusMat 2024年第2期4卷 125-144页

作者： Ling Xiong nannan Li Yi Luo Lei Chen Institutes for Breast Health Medicine West China HospitalSichuan UniversityChengduChina Micro/Nano Fabrication Laboratory Microsystem and Terahertz Research CenterChina Academy of Engineering PhysicsChengduChina Institute of Electronic Engineering China Academy of Engineering PhysicsMianyangChina Department of Neurology Joint Research Institution of Altitude HealthWest China HospitalSichuan UniversityChengduChina

Electroencephalogram(EEG)is one of the most important bioelectrical signals related to brain activity and plays a crucial role in clinical medicine.Driven by continuously expanding applications,the development of EEG materials and technology has attracted considerable attention.However,systematic analysis of the sustainable development of EEG materials and technology is still lacking.This review discusses the sustainable development of EEG materials and technology.First,the developing course of EEG is introduced to reveal its significance,particularly in clinical medicine.Then,the sustainability of the EEG materials and technology is discussed from two main aspects:integrated systems and EEG electrodes.For integrated systems,sustainability has been focused on the developing trend toward mobile EEG systems and big-data monitoring/analyzing of EEG signals.Sustainability is related to miniaturized,wireless,portable,and wearable systems that are integrated with big-data modeling techniques.For EEG electrodes and materials,sustainability has been comprehensively analyzed from three perspectives:performance of different material/structural categories,sustainablematerials for EEGelectrodes,and sustainable manufacturing technologies.In addition,sustainable applications of EEG have been presented.Finally,the sustainable development of EEG materials and technology in recent decades is summarized,revealing future possible research directions as well as urgent challenges.

关键词： clinical medicine electroencephalography technology limitations and future directions materials and electrodes sustainable development

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我国高铁快运潜在市场规模预测

综合运输 2022年第3期44卷 95-100页

作者：施路申皓贺南南李国旗西南交通大学交通运输与物流学院成都610031 中铁二院工程集团有限责任公司成都610031

对我国高铁快运的潜在市场规模预测,有利于优化高铁快运服务质量,支撑高铁快运服务产品开发。以快递量作为潜在转移对象,建立向量自回归模型进行快递量预测;考虑运输安全性、便捷性、经济型、可靠性和时效性等影响因素,构建logit分担率... 详细信息

对我国高铁快运的潜在市场规模预测,有利于优化高铁快运服务质量,支撑高铁快运服务产品开发。以快递量作为潜在转移对象,建立向量自回归模型进行快递量预测;考虑运输安全性、便捷性、经济型、可靠性和时效性等影响因素,构建logit分担率模型进行分担率预测,得到了高铁快运市场可分担率及2020-2025年的潜在市场规模。结果表明,高铁快运市场潜在规模远大于实际市场情况,通过提高寄件服务便捷性,缩减前置等待时间,优化两端作业时间,将有利于提高高铁快运市场占有率。

关键词：高铁快运潜在市场预测 logit模型向量自回归模型

Bicycle dynamics and its circular solution on a revolution surface

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Acta Mechanica Sinica 2020年第1期36卷 220-233页

作者： Jiaming Xiong nannan Wang Caishan Liu State Key Laboratory for Turbulence and Complex Systems College of EngineeringPeking UniversityBeijing100871China

In this paper,we study the dynamics of an idealized benchmark bicycle moving on a surface of revolution.We employ symbolic manipulations to derive the contact constraint equations from an ordered process,and apply the Lagrangian equations of the first type to establish the nonlinear differential algebraic equations(DAEs),leaving nine coupled differential equations,six contact equations,two holonomic constraint equations and four nonholonomic constraint equations.We then present a complete description of hands-free circular motions,in which the time-dependent variables are eliminated through a rotation transformation.We find that the circular motions,similar to those of the bicycle moving on a horizontal surface,nominally fall into four solution families,characterized by four curves varying with the angular speed of the front wheel.Then,we numerically investigate how the topological profiles of these curves change with the parameter of the revolution surface.Furthermore,we directly linearize the nonlinear DAEs,from which a reduced linearized system is obtained by removing the dependent coordinates and counting the symmetries arising from cyclic coordinates.The stability of the circular motion is then analyzed according to the eigenvalues of the Jacobian matrix of the reduced linearized system around the equilibrium position.We find that a stable circular motion exists only if the curvature of the revolution surface is very small and it is limited in small sections of solution families.Finally,based on the numerical simulation of the original nonlinear DAEs system,we show that the stable circular motion is not asymptotically stable.

关键词： Bicycle dynamics Nonholonomic constraints Stability Nonlinear DAEs Circular motion

The up-regulation of Fas/FasL contributes to the apoptosis of HL-60 cells induced by euphorbiasteroid

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The up-regulation of Fas/FasL contributes to the apoptosis o...

Comprehensive RNA-Seq Analysis of Potential Therapeutic Targets of Gan-Dou-Fu-Mu Decoction for Treatment of Wilson Disease using a Toxic Milk Mouse Model

第九届全国免疫学学术大会

作者： GUO Fei LI Xia ZHANG Chao REN Xia shi Mei-yan LAI nannan JIANG Guo-sheng Institute of Basic Medicine Shandong Academy of Medical Sciences

Aim of the study:To investigate the effect of euphorbiasteroid on inducing the apoptosis of HL-60 cells and demonstrate whether the Fas/FasL signaling pathway was involved in the induction of apoptosis.Materials and m...

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Comprehensive RNA-Seq Analysis of Potential Therapeutic Targ...

Uncovering the miRNA-mediated regulatory network involved in Ma bamboo(Dendrocalamus latiflorus)de novo shoot organogenesis

世界中医药学会联合会老年医学专业委员会2021年学术年...

作者： Taohua Wei Wenjie Hao Lulu Tang Huan Wu shi Huang Yue Yang nannan Qian Jie Liu Wenming Yang Xianchun Duan Department of Neurology The First Affiliated Hospital of Anhui University of Chinese Medicine Graduate School Anhui University of Chinese Medicine Key Laboratory of Xin'An Medicine Ministry of Education Scientific Research & Experiment Center Anhui University of Chinese Medicine Institute for Medical Virology Goethe University Frankfurt am Main Department of Pharmacy The First Affiliated Hospital of Anhui University of Chinese Medicine

Background: Gan-Dou-Fu-Mu decoction(GDFMD) improves liver fibrosis in experimental and clinical studies including those on toxic mouse model of Wilson Disease(Model). However, the mechanisms underlying the effect of GDFMD have not been characterized. Herein, we deciphered the potential therapeutic targets of GDFMD using transcriptome analysis. Methods: We constructed a tx-j Wilson disease(WD) mouse model, and assessed the effect of GDFMD on the liver of model mice by hematoxylin and eosin, Masson, and immunohistochemical staining. Subsequently, we identified differentially expressed genes(DEGs) that were upregulated in the Model(Model vs. control) and those that were downregulated upon GDFMD treatment(compared to the Model) using RNA-sequencing(RNA-Seq). Biological functions and signaling pathways in which the DEGs were involved were determined by gene ontology(GO) and Kyoto encyclopedia of genes and genomes(KEGG) pathway analyses. A protein–protein interaction(PPI) network was constructed using the STRING database, and the modules were identified using MCODE plugin with the Cytoscape software. Several genes identified in the RNA-Seq analysis were validated by real-time quantitative PCR. Results: Total of 2124 DEGs were screened through the Model vs. control and Model vs. GDFMD comparisons, and dozens of GO and KEGG pathway terms modulated by GDFMD were identified. Dozens of pathways involved in metabolism(including metabolic processes for organic acids, carboxylic acids, monocarboxylic acids, lipids, fatty acids, cellular lipids, steroids, alcohols, eicosanoids, long-chain fatty acids), immune and inflammatory response(such as complement and coagulation cascades, cytokine–cytokine receptor interaction, inflammatory mediator regulation of TRP channels, antigen processing and presentation, T-cell receptor signaling pathway), liver fibrosis(such as ECM-receptor interactions), and cell death(PI3K-Akt signaling pathway, apoptosis, TGF-beta signaling pathway, etc.) were identified as potential targets of GDFMD in the

关键词： Wilson Disease（WD） Toxic milk mice（TX Mice） Gan-Dou-Fu-Mu decoction（GDFMD） RNA-sequencing Traditional Chinese medicine（TCM）

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Horticulture Research 2023年第12期10卷 1-13页

作者： nannan Wang Wenjia Wang Yang Cheng Changyang Cai Qiang Zhu Basic Forestry and Proteomics Center(BFPC) College of ForestryHaiXia Institute for Science and TechnologyFujian Agriculture and Forestry UniversityFuzhou 350002China

Bamboo is an important non-timber forest product and is well-known for its reluctance to regenerate.Recently we have established a de novo shoot organogenesis(DNSO)protocol in Ma bamboo(Dendrocalamus latiflorus)and revealed the transcriptomic dynamics during Ma bamboo regeneration,which suggested the potential roles of Ma bamboo microRNAs(DlamiRNAs)in this process.However,how DlamiRNAs regulate bamboo DNSO is poorly understood.Here we performed integrated analysis with sRNAome,degradome,and transcriptome sequencing by using samples covering the four stages of the bamboo DNSO process.A total of 727 DlamiRNAs showed differential expression during the bamboo DNSO process,and the core DlamiRNA-DlamRNA-mediated regulatory networks for bamboo DNSO were constructed.Based on the results,DlamiR156 was selected for further functional characterization of its potential roles in bamboo DNSO.Transgenic bamboos with increased DlamiR156 levels exhibited an enhancement in their regeneration efficiency.Conversely,when DlamiR156 levels were downregulated,the regeneration efficiencies of transgenic bamboos decreased.Our findings show that the DlamiRNA-mediated regulatory pathways are significant in the process of bamboo regeneration and will contribute to our understanding of the molecular mechanisms governing plant organogenesis in a more comprehensive manner.

关键词： bamboo Bamboo covering

基于光谱特征的水温对溶解态有机质与铜结合特性影响

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环境科学学报 2024年第3期44卷 199-205页

作者：胡斌张楠楠施玥程伟河海大学浅水湖泊综合治理与资源开发教育部重点实验室南京210024 江苏环保产业技术研究院股份公司南京210019 江苏省苏力环境科技有限责任公司南京210019

利用同步荧光光谱和傅里叶红外光谱结合二维相关光谱分析,探究了不同水温下溶解态有机质(DOM)与Cu^(2+)的结合特性.结果表明,水温对DOM的芳香性和分子量没有影响,对荧光强度有微弱的淬灭作用,这是由于水温变化对酰胺和酚类官能团的影响... 详细信息

利用同步荧光光谱和傅里叶红外光谱结合二维相关光谱分析,探究了不同水温下溶解态有机质(DOM)与Cu^(2+)的结合特性.结果表明,水温对DOM的芳香性和分子量没有影响,对荧光强度有微弱的淬灭作用,这是由于水温变化对酰胺和酚类官能团的影响导致的.此外,水温的改变能够显著地影响DOM与Cu^(2+)的结合强度、结合点位及其结合顺序.同步荧光光谱结果表明,不同水温下DOM与Cu^(2+)结合能力由大到小的顺序为25℃→35℃→15℃.傅里叶红外光谱结果进一步表明,随着水温的升高,多糖/醇类C—O官能团与Cu^(2+)的结合能力明显降低,而酚类C—O和羧基C=O的作用明显增强.因此,更应关注冬季水体中重金属的生物有效性和生态风险.研究结果可为DOM与重金属的生物地球化学循环过程提供基础数据和理论支撑.

关键词：荧光光谱有机质傅里叶红外光谱二维相关光谱分析水温