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Scopolin isolated from Erycibe obtusifolia Benth stems suppresses adjuvant-induced rat arthritis by inhibiting inflammation and angiogenesis

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沈阳药科大学学报 2008年第S1期25卷 107-108页

作者： PAN Rong1,DAI Yue1,GAO Xing-hua1,XIA Yu-feng2(1.Department of Pharmacology of Chinese Materia Medica,China Pharmaceutical University,nanjing 210038,China 2.Department of Chinese Materia Medica Analysis,China Pharmaceutical University,nanjing 210038,China)

Objective To study the effects and mechanisms of scopolin isolated from the stems of Erycibe obtusifolia Benth in arthritis-associated inflammation and *** Adjuvant-induced arthritic rat,an animal model for human RA was used in this study for examining the potential remedial effect of *** swelling in both inoculated and non-inoculated paws,body weights and articular index(AI)scores were detected to evaluate the severity of the *** assessment of tissue sections from rat ankles was also ***,the blood vessel density in the synovial tissues was quantitatively *** addition,expressions of VEGF,FGF-2,TNF-α,IL-1β and IL-6 in rat synovial tissues were determined by immunohistochemistry assay in an attempt to explain the mechanisms of scopolin for suppressing *** Scopolin dose-dependently inhibited both inoculated and non-inoculated paw swelling in rat *** mean AI scores of scopolin treated groups were also dose-dependently lower than that of model *** addition,compared with the weights of model group,the mean body weights of rats treated with scopolin(50,100 mg·kg-1)were higher from day 13 to 22,perhaps indicative of healthier *** histologic architecture of the joint was highly abnormal in the model group rats,while high dose of scopolin treated rats preserved a nearly normal histologic architecture of the ***,the new blood vessels were reduced dose-dependently in the synovial tissue of rat AIA treated with ***,scopolin reduced the overexpression of IL-6,VEGF and FGF-2 in rat synovial *** Scopolin is capable of reducing clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis,and this compound may be a potent therapeutic agent for angiogenesis related diseases and can serve as structural base for screening for more potent synthetic analogs.

关键词： scopolin rheumatoid arthritis angiogenesis inflammation VEGF FGF-2 TNF-α IL-1β

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A preliminary study on interaction of Hg and Se in Sedum alfredii Hance

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Acta Geochimica 2006年第S1期 127-128页

作者： Xuebin YIN, Chunxia YAO, De BI, Yongming LUO, Jing SONG Soil and Environment Bioremediation Research Center, nanjing Institute of Soil Science, Chinese Academy of Sciences, nanjing 210008, China

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GaAs MESFET的背栅效应研究

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固体电子学研究与进展 1989年第2期9卷 164-171页

作者：赵大德南京电子器件研究所

本文着重研究了分立GaAc耗尽型MESFET背栅效应的光敏性和尺寸效应。本文还采用一种实验方法——器件在光照下,观察栅压的调制作用,解释了背栅效应机理。不同栅压下,背栅效应的大小不同,零栅压下的背栅效应比负栅偏压下的背栅效应更小。... 详细信息

本文着重研究了分立GaAc耗尽型MESFET背栅效应的光敏性和尺寸效应。本文还采用一种实验方法——器件在光照下,观察栅压的调制作用,解释了背栅效应机理。不同栅压下,背栅效应的大小不同,零栅压下的背栅效应比负栅偏压下的背栅效应更小。发现衬底峰值电流与背栅效应有密切关系。

关键词： GaAs MESFET 背栅效应

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Variation of cellular biochemical compositions of the marine microalgae Pavlova viridis （Prymnesiophyceae） under laboratory and outdoor culture conditions

Variation of cellular biochemical compositions of the marine...

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中国海洋湖沼学会第九次全国会员代表大会暨学术研讨会

作者： Changwei Hu Mei Li Jianlong Li Qin Zhu Zhili Liu(1.Department of Biological Science and Technology,School of Life Science,nanjing University,nanjing 210093,China 2.National Key Laboratory of Pollution Control and Resource Reuse of China,School of the Environment,nanjing University,nanjing 210093,China)

＜正＞The marine microalgae Pavlova viridis （Prymnesiophyceae） is widely used in marine aquaculture industries to feed bivalves and proposed as an alternative source of *** investigate variation of its biochemical c... 详细信息

关键词： Eicosapentaenoic acid (EPA) Outdoor cultivation Pavlova viridis

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Robust Actuator Fault Estimation for Satellite Control System via Fuzzy Proportional Multiple-integral Observer Method

Robust Actuator Fault Estimation for Satellite Control Syste...

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第二十九届中国控制会议

作者： FU Yanping 1,CHENG Yuehua 1,2,JIANG Bin 1 1.College of Automation Engineering,nanjing University of Aeronautics and Astronautics,nanjing 210016,P.R.China2.Academy of Frontier Science,nanjing University of Aeronautics and Astronautics,nanjing 210016,P.R.China

In this paper,a novel actuator fault estimation scheme based on T-S fuzzy proportional multiple-integral（PMI） observer is developed for satellite attitude control system（ACS）.The nonlinear dynamics of ACS is represented by T-S fuzzy *** the actuator fault and its derivative are introduced as an augmented *** proportional multiple-integral observer is designed to estimate both the system state and the actuator fault simultaneously and *** method is proved to be suitable for soft fault *** issue is considered with respect to input disturbance in the satellite *** effectiveness of our proposed fault diagnosis is demonstrated through numerical simulations.

关键词： Satellite Attitude Dynamics T-S Fuzzy Model Actuator Fault Estimation Fuzzy Proportional Multiple-integral Observer Robustness

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Preparation and Characterization of Nanoencapsulated Tetradecane as Phase Change Material for Cool Thermal Energy Storage

Preparation and Characterization of Nanoencapsulated Tetrade...

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2008国际低温与制冷大会

作者： Yang F Zhang M Wu S M Fang G Y Department of Physics nanjing University nanjing 210093 P.R.China

＜正＞Nanoencapsulated phase change material（PCM） is prepared by using in-situ polymerization *** is used as core material,which melts and solidifies at 5.7℃with a specific latent heat of 217kJ/*** and formaldehyde are used for the shell *** dodecyl sulfate（SDS） is used as the emulsifier and Resorcin is used as the system modifier. Characterization of the morphology of the nanocapsules is carried out by a scanning electronic microscopy（SEM） and the thermal properties is investigated by a differential scanning calorimeter （DSC）.The SEM analysis indicates that the nanocapsules have an average size of 100nm and are well coated,uera-formaldehyde polymer particles adhered firmly around the surface of the *** analysis indicates that the mass content of tetradecane is up to 81%,which resulted in a latent heat of 176kJ/kg of the *** phase change temperature of the capsules is 5.4℃,a little lower than pure *** nanocapsules have good water endurance and can form stable phase change suspension with *** phase change point of the nanoencapsulated tetradecane is within the evaporating temperature range of the air-conditioning system,it’s potential to be used in the cool thermal energy storage air conditioning systems.

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A Dual Optimization Model of Fixture Design for the Thin-walled Workpiece

A Dual Optimization Model of Fixture Design for the Thin-wal...

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2007 10th IEEE International Conferences on Computer Aided Design and Computer Graphics(CAD/Graphics 2007)

作者： Weifang Chen,Hua Chen,Lijun Ni and Jianbin Xue nanjing University of Aeronautics and Astronautics,No.29,Yudao Street,nanjing 210016 China

The deformation must be controlled during machining,especially for the thin-walled *** layout and clamping force are the major two aspects that influence the degree and distribution of machining *** this paper,a dual optimization model of fixture layout and dynamic clamping force has been established for machining the thin-walled ***,an optimal fixture layout is generated by considering the deformation degree and ***,dynamic clamping force are optimized based on the optimal fixture *** finite element method is used to analyze the workpiece deformation.A genetic algorithm is developed to solve the optimization ***,an example is used to illustrate that a satisfactory result has been obtained,which is far superior to the experiential *** optimization method can reduce the machining deformation effectively and improve the distribution condition.

关键词： A Dual Optimization Model of Fixture Design for the Thin-walled Workpiece Model

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CHARACTERISTICS OF THE REGIONAL TOURISM TRANSPORT NETWORK——taking the tourism region along the Yangtze River as an example

CHARACTERISTICS OF THE REGIONAL TOURISM TRANSPORT NETWORK—...

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第一届交通运输工程国际学术会议

作者： J. Zhong and J. Zhang Department of Land Resources and Tourism Sciences, nanjing University, nanjing 210093, P. R. China

The aim of this paper is to explore characteristics of overland transport network of tourism cities along the Yangtze River. General characteristics and accessibility of tourism transport network are both investigated. The result shows that a good structure of transport network does not always ensure high accessibility. In order to learn the transport network comprehensively, we propose general characteristics and accessibility should be researched at the same time. Finally, we put forward some specific suggestions for development of tourism transport network in this tourism region.

关键词： tourism region transport network accessibility

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一种基于关系数据库的友好查询语言GBD

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数据采集与处理 1994年第1期9卷 34-43页

作者：李正坤董逸生南京市经济信息中心东南大学计算机系

数据库管理的主要功能之一是查询处理，查询功能的完备性和操作界面的友好性是数据库应用的基本要求。ＧＢＤ查询语言即是以这一基本要求为目标，以ＦＯＸ数据库的应用为背景，并借鉴ＳＱＬ语言的查询功能特点进行研制的。ＧＢＤ语言以... 详细信息

数据库管理的主要功能之一是查询处理，查询功能的完备性和操作界面的友好性是数据库应用的基本要求。ＧＢＤ查询语言即是以这一基本要求为目标，以ＦＯＸ数据库的应用为背景，并借鉴ＳＱＬ语言的查询功能特点进行研制的。ＧＢＤ语言以可交互式函数方式定义关系集合运算，以表格形式将查询语言的结构与查询交互界面相统一，以数学运算的递归原理实现语言对查询问题的处理过程。ＧＢＤ语言的设计独立于具体的数据库管理系统，可在多种关系数据库上实现。

关键词：管理系统关系型数据库 GBD语言

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ERROR ANALYSIS IN DIFFERENTIAL QUADRATURE METHOD

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Transactions of nanjing University of Aeronautics and Astronautics 1994年第2期11卷 194-200页

作者： He Beiqing(College of Science,NUAA 29 Yudao Street,nanjing 210016,P.R.China)Wang Xinwei(Department of Aircraft Engineering ,NUAA 29 Yudao Street,nanjing 210016,P.R.China)

Error estimation for the differential quadrature (DQ)with various sets of grid spacing is presented. A general formula is given to compute the weighting coefficients directly. It is found that the maximum error of the Do method with roots of Chebyshev polynomials including two end POints (-1 and + 1 ) is the smallest among the several sets of grid spacing investigated herein.

关键词： error estimate weight grid spacers differential quadrature harmonic differential quadrature

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