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Provenance and Paleoclimate of the Triassic to Middle Jurassic Adigrat Sandstone,Blue Nile Basin,Central Ethiopia

Acta Geologica Sinica(English Edition) 2024年第4期98卷 1007-1020页

作者： Bekele BARSISA Ayalew DEREJE Kidanemariam GIlAMICHAEl Atnafu BAlEMWAl Raphaël PIK Department of Earth Sciences Wollega UniversityNekemteEthiopia Department of Earth Sciences Addis Ababa UniversityAddis AbabaEthiopia Departments of Anthropology Geography and GeologyEast Los Angeles CollegeLos AngelesCaliforniaUSA CRPG(UMR 7358 CNRS&Universitéde lorraine) 15 rue ND des pauvres BP2054501 Vandoeuvre-Lès-Nancy CedexFrance

Mineralogical and geochemical studies have been undertaken on the Triassic to lower Jurassic Adigrat Sandstone of the Blue Nile Basin of central Ethiopia to infer its source rock type,paleoweathering,and paleoclimatic *** Adigrat Sandstone occurs at the basal section of the Mesozoic sedimentary formation and unconformably overlays the Neoproterozoic–Paleozoic crystalline rocks,or locally,the Karroo sediments in the northern Blue Nile Basin.A mineralogical study reveals that quartz(Q),feldspars(F),and lithic fragments(l)are the framework grains of the *** the QFl diagram,the plot of the modal composition of the sandstone mainly falls within the feldspathic arenite and quartzose arenite *** geochemical data of the lower section of the sandstone mainly falls within the arkose and subarkose fields,whereas the upper section data falls within the quartzose and sublithic arenite *** and geochemical weathering indices indicate that the provenances of the Adigrat Sandstone were exposed to pronounced weathering intensity,where the lower part of the sandstone was controlled by arid to semi-arid conditions,whereas the upper section was linked to humid to semi-humid(tropical to subtropical)climatic *** and geochemical data also indicate that mafic to intermediate basement rocks were the primary source rocks of the *** the sediment was assumed to have been reworked by multi-cyclic sedimentary *** discriminant function diagram,the REE pattern,la/Th ***/Yb,and the Th–Hf–Co plot are consistent.A comparison of provenance studies for the Adigrat Sandstone in the Blue Nile Basin and the Mekele outlier of northern Ethiopia indicates that the sediment of the former is highly sorted,experienced higher weathering intensity,and compositionally derived from mafic to intermediate crystalline *** the other hand,the sediment of the latter is essentially a weathering product of felsic rocks.

关键词： mineralogical geochemical paleoweathering humid provenance Adigrat Sandstone

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Utility of the low-accelerating-dose regimen in 182 liver recipients with recurrent hepatitis C virus

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World Journal of Gastroenterology 2015年第20期21卷 6236-6245页

作者： Kieron Bl lim Hamid R Sima M Isabel Fiel Viktoriya Khaitova John T Doucette Maria Chernyiak Jawad Ahmad nancy Bach Charissa Chang Priya Grewal leona Kim-Schluger lawrence liu Joseph Odin Ponni Perumalswami Sander S Florman Thomas D Schiano Division of liver Diseases Icahn School of Medicine at Mount Sinai Division of Gastroenterology and Hepatology National University Center for Organ TransplantationNational University Hospital lillian and Henry M Stratton-Hans Popper Department of Pathology Icahn School of Medicine at Mount Sinai Recanati-Miller Transplantation Institute Icahn School of Medicine at Mount Sinai Department of Preventive Medicine Icahn School of Medicine at Mount Sinai

AIM: To describe our experience using a low-acceleratingdose regimen(lADR) with pegylated interferon alpha-2a and ribavirin in treatment of hepatitis C virus(HCV) recurrence. METHODS: From 2003, a protocolized lADR strategy was employed to treat liver transplant(lT) recipients with recurrent HCV at our institution. Medical records of 182 adult patients with recurrent HCV treated with lADR between 1/2003 and 1/2011 were reviewed. Histopathology from all post-lT liver biopsies were reviewed in a blinded fashion. Paired recipient and donor Il28 B status were assessed. A novel technique was employed to ascertain recipient and donor Il28B(rs12979860) Gt data using DNA extracted from archival FFPE tissue from explanted native livers and donor gallbladders respectively. The primary endpoint was SVR; secondary endpoints examined include(1) patient and graft survival;(2) effect of anti-viral therapy on liver histology(fibrosis and inflammation);(3) incidence of on-treatment development of ACR, CDR, or PCH;(4) association of recipient and donor Il28 B genotype with SVR; and(5) incidence of antiviral therapy-associated adverse events(anemia, leukopenia, thrombocytopenia, depression) and hepatic ***: The overall SVR rate was 38%(29% Gt1, 67% Gt2, 86% Gt3 and 58% Gt4). HCV Gt(P lovirus mismatch(P = 0.001), baseline serum bilirubin(P = 0.002), and baseline viral load(P = 0.04) were independent predictors for SVR. SVR rates were significantly higher in the recipient-CC/donor-non CC pairs(P = 0.007). Neither baseline fibrosis nor change in fibrosis stage after anti-viral therapy were associated with SVR. Fibrosis progressed in 72% of patients despite SVR. Median graft survival was 91 mo. Five-year patient survival was superior in patients who achieved SVR(97% vs 82%, P = 0.001). Pre-treatment AlP ≥ 150 U/l(P = 0.01), total bilirubin ≥ 1.5 mg/d l(P = 0.001) and creatinine ≥ 2 mg/d l(P = 0.001) were independently associated

关键词： Hepatitis C recurrence liver transplant low accelerating dose regimen Peginterferon α-2a Il28B

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埃塞俄比亚发展花卉业动力强劲

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中国花卉园艺 2006年第15期 50-51页

作者： nancy laws 钟云芳法国l’Estrechure

埃塞俄比亚位于东非高原,具有独特的高原气候条件和丰富的水利资源。目前埃塞俄比亚尚处市场经济发展的起步阶段,外资政策优惠,租赁土地价格低廉,并拥有众多的廉价劳动力。这些都为花卉业的发展提供了难得的条件,产品在国际花卉市场上... 详细信息

埃塞俄比亚位于东非高原,具有独特的高原气候条件和丰富的水利资源。目前埃塞俄比亚尚处市场经济发展的起步阶段,外资政策优惠,租赁土地价格低廉,并拥有众多的廉价劳动力。这些都为花卉业的发展提供了难得的条件,产品在国际花卉市场上极具竞争力。

关键词：埃塞俄比亚花卉业水利资源气候条件经济发展土地价格劳动力竞争力高原外资

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先天性心脏病麻醉协会会议综述

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麻醉与镇痛 2008年第4期4卷 99-100页

作者： nancy l. Glass Robert D. Valley 刘克玄(译) 陈秉学(校) Departments of Pediatrics and Anesthesiology Baylor College of Medicine Houston Texas University of North Carolina School of Medicine Chapel Hill North Carolina 不详

借助2007年儿科麻醉学大会成功举办的契机，先天性心脏病麻醉协会（The Congenital Cardiac Anesthesia Society，CCAS）在亚利桑那州菲尼克斯市成立，并召开了第一次会议。儿科心脏病重症监护协会（PICU）在此之前成功举办了两个关于... 详细信息

借助2007年儿科麻醉学大会成功举办的契机，先天性心脏病麻醉协会（The Congenital Cardiac Anesthesia Society，CCAS）在亚利桑那州菲尼克斯市成立，并召开了第一次会议。儿科心脏病重症监护协会（PICU）在此之前成功举办了两个关于儿科心脏病麻醉的会议，为CCAS的成立奠定了基础。今后，CCAS年会将分别与冬季儿科麻醉协会（Winter Socity for Pediatric Anesthesia）庄羡国儿科学会赞助的儿科麻醉协会和儿科心脏病重症监护协会轮流召开年会。

关键词：先天性心脏病麻醉学协会综述重症监护儿科年会

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Incipient charnockites from southern India:The role of brines

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Geoscience Frontiers 2019年第5期10卷 1789-1801页

作者： Jacques l.R. Touret Robert C. Newton Michel Cuney 121 Rue de la Réunion F-75020ParisFrance Department of Earth Planetary and Space SciencesUCLALos AngelesCAUSA Université de lorraine CNRS-CREGUGeoRessources BP70239F-54506Vandoeuvre-les-Nancy CedexFrance

Southern India and Sri-lanka are the places where “incipient charnockites”,*** local transformation of amphibolite-facies gneisses into orthopyroxene-bearing,igneous looking charnockites,have been discovered in the early *** fact that some incipient charnockites occur along a network of brittle fractures,together with CO2 remnants preserved in mineral inclusions,had called for the role of fluids during charnockite *** present work presents new observations on fluid inclusions and microtextures of incipient charnockites from type localities in southern *** addition to CO2-rich fluid inclusions in quartz and feldspar,all of the occurrences have disrupted remnants of concentrated aqueous alkali chloride ***2 inclusions are more abundant in paragneiss (Kerala) than in orthogneiss (Karnataka/Tamil Nadu).The finding of disrupted brine inclusions in the Kabbal charnockite is a key link between closely associated massive charnockites and Closepet Granite,both of which also share the brine *** of the occurrences studied here have feldspar or feldspar-quartz microvein networks along grain boundaries of recrystallized quartz,feldspar and *** metasomatic veins again indicate the action of alkali-exchanging fluids (i.e.,saline solutions).Feldspar microveins,which have been found in most “massive” charnockites,along with the CO2-rich fluid inclusions,suggest a commonality of incipient charnockite and massive charnockite,both types differing in intensity of interaction with metasomatizing pore fluids.

关键词： Incipient charnockite High-grade crustal metamorphism CO2 Brine metasomatism

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Isolation of Picocyanobacteria (Order Synechococcales) and Occurrence of the Cyanotoxin Anatoxin-A in a Shallow Mesotrophic Pond

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Journal of Water Resource and Protection 2023年第9期15卷 299-314页

作者： nancy J. leland Kimberley Crocker Pearson Marty K. Burke Jeffrey T. Miller Alison Watts James F. Haney Department of Biological Sciences University of New Hampshire Center for Freshwater Biology and Ecotoxicology Durham New Hampshire USA lim-Tex North Andover Massachusetts USA Brewster Natural Resources Advisory Commission Brewster Massachusetts USA Brewster Ponds Coalition Brewster Massachusetts USA Department of Civil and Environmental Engineering University of New Hampshire College of Engineering and Physical Sciences Durham New Hampshire USA

We have verified the use of a serial filtration method to isolate picocyanobacteria for analysis. We used eDNA metabarcoding to confirm the picocyanobacteria as members of the Order Synechococcales, Genus Cyanobium, specifically Cyanobium 6307. Fluorometric analysis using accessory pigments phycocyanin and phycoerythrin described periods of excess biomass, where the net growth rate model confirmed these conditions. The total anatoxin-a concentrations in the picocyanobacterial sample ranged from 0.0074 - 6.41 μg·l-1 representing a 40-fold difference over the entire sampling season. Sampling frequency of every three days appeared to be an important factor in capturing these changes in anatoxin-a concentration. During a period of excess biomass, we were able to establish a linear correlation between cyanobacterial biomass and Anatoxin-a concentrations.

关键词： Picocyanobacteria Anatoxin-a eDNA Phycocyanin Phycoerythrin

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数字学术信息交流的现行模式（下）——Ithaka为ARl所作的一项调查报告

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图书情报工作动态 2009年第1期 1-11页

作者： nancy l．Maron K．Kirby Smith 陈成鑫（编译）王丹丹（编译）鲁超（编译）徐刘靖（编译）

5数字学术资源的种类虽然许多学术资源是由几种类型的正式和非正式内容组合而成，我们发现在所选取的样本中大多数原创的学术资源以一种主要类型为主。为了进行分析，我们逐一把206种资源划归到8种内容类别中。对于资源包含多种内容类... 详细信息

5数字学术资源的种类虽然许多学术资源是由几种类型的正式和非正式内容组合而成，我们发现在所选取的样本中大多数原创的学术资源以一种主要类型为主。为了进行分析，我们逐一把206种资源划归到8种内容类别中。对于资源包含多种内容类型的情况（如包含博客的Eonly期刊），我们根据研究人员列出的使用该内容的网站的元素将其归类，或者根据看上去占主导地位的内容类型将其归类。

关键词：学术信息交流现行模式 ARl 学术资源研究人员非正式种类归类

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Clinical impact of hepatitis B and C virus envelope glycoproteins

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World Journal of Gastroenterology 2013年第5期19卷 654-664页

作者： Hélène Jeulin Aurélie Velay John Murray Evelyne Schvoerer Virology laboratory Centre Hospitalier Universitaire de NancyVandoeuvre-lès-NancyF-54511France EA RHEM 4369 Universitéde LorraineF-54000 NancyFrance School of Mathematics and Statistics University of New South WalesSydneyNSW 2052Australia The Kirby Institute University of New South WalesSydneyNSW 2052Australia

Chronic infection by either hepatitis B virus(HBV)or hepatitis C virus(HCV)share epidemiological characteristics with risks for development of severe complications such as liver cirrhosis and hepatocellular *** and HCV also share a high genetic variability. Among highly variable regions,viral genes encoding surface proteins(hepatitis B surface antigen,E1/E2 HCV glycoproteins)play key roles in the stimulation of the host-related immune response and viral entry into *** segments of HBV envelope proteins(preS1,"a"determinant)are crucial in the entry process into permissive *** entry is a complex multistep process involving multiple cell cofactors (glycosaminoglycans,low density lipoprotein receptor, SR-B1,CD81,claudin-1,occludin,EGFR,EphA2)in the interaction with HCV E1/E2 envelope *** vitro both viruses can be controlled by antibody-me-diated neutralization targeting viral envelope,also essential in preventing HBV infection in vivo as observed through successful vaccination using HBs *** preventive vaccination and/or therapeutic pressure can influence HBV and HCV *** HBV,the patterns of antiviral drug resistance in chronic hepatitis are complex and the original pol/S gene overlap has to be taken into ***-induced HBV mutations in pol could indeed generate S mutants with subsequent modified antigenicity or increased cancer *** of HBV and HCV envelope proteins combining high exposure to selective pressures and crucial functional roles require investigation in the context of diagnostic,vaccination and treatment *** this editorial a synthesis is performed of HBV and HCV envelope properties at the entry step and as antigenic proteins,and the subsequent clinical impact.

关键词： Hepatitis B Hepatitis C Viral envelope glycoproteins Clinical outcome

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Associations of accelerometry-measured and self-reported physical activity and sedentary behavior with skeletal muscle energetics:The Study of Muscle,Mobility and Aging(SOMMA)

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Journal of Sport and Health Science 2024年第5期13卷 621-630页

作者： Yujia(Susanna)Qiao Terri l.Blackwell Peggy M.Cawthon Paul M.Coen Steven R.Cummings Giovanna Distefano Samaneh Farsijani Daniel E.Forman Bret H.Goodpaster Stephen B.Kritchevsky Theresa Mau Frederico G.S.Toledo Anne B.Newman nancy W.Glynn Department of Epidemiology School of Public HealthUniversity of PittsburghPittsburghPA 15261USA San Francisco Coordinating Center California Pacific Medical Center Research InstituteSan FranciscoCA 94143USA Department of Epidemiology and Biostatistics University of CaliforniaSan FranciscoCA 94143USA Translational Research Institute AdventHealthOrlandoFL 32804USA Department of Medicine(Geriatrics and Cardiology) University of Pittsburghand GeriatricsResearchEducationand Clinical Center(GRECC)VA Pittsburgh Healthcare SystemPittsburghPA 15261USA Department of Internal Medicine Section on Gerontology and Geriatric MedicineWake Forest School of MedicineWinston-SalemNC 27109USA Division of Endocrinology and Metabolism Department of MedicineUniversity of PittsburghPittsburghPA 15261USA

Background:Skeletal muscle energetics decline with age,and physical activity(PA)has been shown to offset these declines in older ***,many studies reporting these effects were based on self-reported PA or structured exercise ***,we examined the associations of accelerometry-measured and self-reported PA and sedentary behavior(SB)with skeletal muscle energetics and explored the extent to which PA and sedentary behavior would attenuate the associations of age with muscle ***:As part of the Study of Muscle,Mobility and Aging,enrolled older adults(n=879),810(age=76.4±5.0 years old,mean±SD;58%women)had maximal muscle oxidative capacity measured ex vivo via high-resolution re spirometry of permeabilized myofibers(maximal oxidative phosphorylation(maxOXPHOS))and in vivo by ^(31)phosphorus magnetic resonance spectroscopy(maximal adenosine triphosphate(ATP_(max))).Accelerometry-measured sedentary behavior,light activity,and moderate-to-vigorous PA(MVPA)were assessed using a wrist-worn ActiGraph GT9X over 7 ***-reported sedentary behavior,MVPA,and all PA were assessed with the Community Healthy Activities Model Program for Seniors(CHAMPS)*** regression models with progressive covariate adjustments evaluated the associations of sedentary behavior and PA with muscle energetics,as well as the attenuation of the age/muscle energetics association by MVP A and sedentary *** a sensitivity analysis,we also examined activPAl-measured daily step count and time spent in sedentary behavior and their associations with muscle ***:Every 30 min/day more of ActiGraph-measured MVPA was associated with 0.65 pmol/(s×mg)higher maxOXPHOS and 0.012 mM/s higher ATP_(max)after adjusting for age,site/technician,and sex(plight activity was not associated with maxOXPHOS or ATP_(max).Meanwhile,every 30 min/day spent in ActiGraph-measured sedentary behavior was associated with 0.39 pmol/s×mg lower maxOXPHOS and0.

关键词： Aging Exercise Mitochondria

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谁想成为科学家？选择科学作为职业 choosing science as a career 1版

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丛书名：科学咖啡馆系列

2006年

作者：南希·罗斯韦尔（nancy Rothwell）乐爱国译

本书所涉及的话题包括博士专业方向或博士后职位的选择，成功的面谈和求职履历的准备，如何处理好与导师的关系，怎样进行成功的演讲，如何发表高质量的论文并成为知名者，还有当今许多科学研究中的重要方面，包括道德规范和学术欺诈，... 详细信息

ISBN: (数字)7542841033

ISBN: (纸本)7542841033

本书所涉及的话题包括博士专业方向或博士后职位的选择，成功的面谈和求职履历的准备，如何处理好与导师的关系，怎样进行成功的演讲，如何发表高质量的论文并成为知名者，还有当今许多科学研究中的重要方面，包括道德规范和学术欺诈，知识产权和技术开发，以及如何向公众传播科学等内容。

关键词：文化、科学、教育、体育科学、科学研究

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