检索结果-南通市图书馆

A Collaborative Service to the Community: A COVID Vaccine Clinic Provided by a Mid-State University

Open journal of Nursing 2022年第7期12卷 496-504页

作者： Amanda j. Flagg Sherri L. stevens joyce Finch Michelle Finch Barbara Lancaster Tabby Ragland School of Nursing Middle Tennessee State University Murfreesboro TN USA

The opportunity to offer immediate service to a local community in need of an additional COVID Vaccine Clinic was welcomed by the School of Nursing (SON) at Middle Tennessee State University (MTSU). This opportunity not only opened a door by providing a much-needed community service but also afforded students an enriching opportunity to enhance their clinical skills in a venue not always recognized as an available or accessible resource. A COVID Vaccine Clinic was planned in collaboration with the School of Nursing, University Health Services, and the County Health Department to provide COVID vaccines to the Middle Tennessee area. A multidisciplinary committee met weekly to organize the COVID Vaccine Clinic opening this opportunity to the community two days per week. During the initial COVID Vaccine Clinic planning committee meetings, a variety of roles and responsibilities were identified to ensure the clinic would be planned, coordinated, and organized as efficiently as possible. When the clinic opened, weekly meetings continued to identify issues such as supply distribution problems, procedures related to various aspects of care, and debriefings describing the activities of each clinic day to note any areas in need of improvements. The School of Nursing Lobby, located on the MTSU campus, was the designated area chosen for the clinic. Many faculty and students along with numerous campus volunteers worked together enabling thousands of members of the community to receive vaccinations. The interdisciplinary experience was a success and served to bring positive learning outcomes to all members of the faculty and students involved.

关键词： COVID Vaccine Clinic Nursing Education Student Learning

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In vitro expression and analysis of the 826 human G protein-coupled receptors

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Protein & Cell 2016年第5期7卷 325-337页

作者： Xuechen Lv junlin Liu Qiaoyun Shi Qiwen Tan Dong Wu john j. Skinner Angela L. Walker Lixia Zhao Xiangxiang Gu Na Chen Lu Xue Pei Si Lu Zhang Zeshi Wang Vsevolod Katritch Zhijie Liu Raymond C. stevens iHuman Institute ShanghaiTech University Shanghai 201210 China Department of Biological Sciences Bridge Institute University of Southern California Los Angeles CA 90089 USA

G protein-coupled receptors （GPCRs） are involved in all human physiological systems where they are responsible for transducing extracellular signals into cells. GPCRs signal in response to a diverse array of stimuli including light, hormones, and lipids, where these signals affect downstream cascades to impact both health and disease states. Yet, despite their importance as therapeutic tar- gets, detailed molecular structures of only 30 GPCRs have been determined to date. A key challenge to their structure determination is adequate protein expression. Here we report the quantification of protein expression in an insect cell expression system for all 826 human GPCRs using two different fusion constructs. Expression char- acteristics are analyzed in aggregate and among each of the five distinct subfamilies. These data can be used to identify trends related to GPCR expression between dif- ferent fusion constructs and between different GPCR families, and to prioritize lead candidates for future structure determination feasibility.

关键词： G protein-coupled receptors insect,protein expression surface expression analysis fusionconstruct

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Serotonin uptake rates in platelets from angiotensin II-induced hypertensive mice

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Health 2013年第4期5卷 31-39页

作者： Preeti Singh Terry W. Fletcher Yicong Li nancy j. Rusch Fusun Kilic Department of Biochemistry and Molecular Biology College of Medicine The University of Arkansas for Medical Sciences Little Rock USA Department of Pharmacology and Toxicology College of Medicine The University of Arkansas for Medical Sciences Little Rock USA

Angiotensin II (Ang II) is a critical component of the reninangiotensin system that contributes to hypertension. Although platelets in blood from hypertensive subjects have an abnormal biological profile, it is unclear if circulating Ang II influences platelet aggregation or thrombus formation. One of the abnormalities presented to the platelets during hypertension is an elevated plasma concentration of serotonin (5-HT) caused by reduced 5-HT uptake secondary to loss of the 5-HT transporter (SERT) on the platelet plasma membrane. In the current study, we evaluated in vivo platelet function after 7 days of subcutaneous Ang II infusion to establish hypertension in mice and additionally assessed the biology of isolated platelets exposed to Ang II in vitro. The administration of Ang II elevated systolic blood pressure, but markers of platelet activation including P-selectin and PEjon/A staining were not changed. However, the aggregation response to collagen was reduced in isolated platelets from Ang II-infused mice, which also showed reduced 5-HT uptake by SERT. In vitro exposure of isolated platelets to Ang II also resulted in a loss of surface SERT associated with a reduced aggregation response to collagen. These abnormalities were reversed by increasing concentra tions of the Ang II receptor antagonist, valsartan. Interestingly, SERT KO mice failed to fully develop hypertension in response to Ang II infusion and isolated platelets from these animals were insensitive to the anti-aggregatory influence of Ang II. Thus, Ang II blunts the aggregation responses of platelets and the mechanism underlying this action may involve a loss of SERT on the platelet plasma membrane. The latter event depletes intracellular 5-HT in platelets, an event that is associated with reduced aggregation. The widespread use of antihypertensive drugs that target the renin-angiotensin system suggest the potential clinical utility of our findings and emphasize the importance of understanding the i

关键词： Serotonin Angiotensin Platelet Hypertension

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A Longitudinal Study of Knowledge, Attitudes and Self-Efficacy in Pregnant Asthmatics

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Open journal of Nursing 2013年第8期3卷 524-531页

作者： nancy j. MacMullen Sharon Telleen Mahmoud Ismail Linda F. Samson Phyllis jones Governors State University University Park USA Maternal-Fetal Medicine University of Chicago Chicago USA University of Illinois at Chicago Chicago USA

The objectives of this study of pregnant women with asthma are 1) to describe their knowledge and attitudes of asthma in pregnancy and their self-efficacy in carrying out their self-management plan during pregnancy, 2) to determine if their knowledge, attitudes, and self-efficacy changed as their pregnancy progressed, and 3) to ascertain the relationship between knowledge, attitudes, and self-esteem and age, education, trimester of pregnancy, weeks of pregnancy, the number of times pregnant and live births. Sixty-eight pregnant women who had an asthma diagnosis were given knowledge, attitudes and self-efficacy questionnaires initially during the point of first contact (first or second) trimester (Time I) and subsequently during the latter part of their pregnancy (third trimester) (Time II). A demographic data form was also administered at Times I and II. Data were collected in an urban academic medical clinic and analyzed using SPSS 17. Data analysis utilized frequencies, paired samples t tests, and linear regression. There were no significant differences between Time I and Time II in attitudes and self-efficacy. Significant differences were limited to the knowledge questionnaire (t = 4.370, p = 0.05). There was a significant relationship between education and knowledge. Pregnant women with asthma had gaps in their knowledge of asthma in pregnancy, although their knowledge increased as their pregnancy progressed from Time I to Time II. Also, the more education the women had, the better they understood asthma. Education for pregnant women with asthma is tailored to their needs and modified as necessary. Nurses are prepared to address this challenge.

关键词： Asthma Pregnancy Complications Knowledge Attitudes Self-Efficacy

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孩子，让我携你走向成功

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丛书名： Free Spirit超完美成长计划丛书

2004年

作者：（美）j. L. Roehlkepartain （美）nancy Leffert等郭立颖译

本书提供了1000多个实用而又创造性的办法，来建立所有这40项有益于0～11岁儿童的成长财富。“成长财富”按类别分为八部分，即支持、授权、约束与期望、建设性地利用时间、致力于学习等。

ISBN: (纸本)7543316730

关键词：文化、科学、教育、体育教育家庭教育

来源：汇雅图书（南通市图书馆... 评论

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SimMarket research student playbook / nancy j. Nentl, Craig Miller.

SimMarket research student playbook / Nancy J. Nentl, Craig ...

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2003年

作者： nancy j. Nentl Craig Miller.

来源：畅想之星图书光盘版（南... 评论

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Research integration for health sciences libraries

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中华医学图书情报杂志 2018年第1期27卷 15-21页

作者： nancy j.Allee Taubman Health Sciences Library University of Michigan

This article is a case study of an innovative academic health sciences library initiative that describes the planning and events in the inaugural year of a new library research program. In response to emerging trends in health sciences libraries to increase research skills of librarians in order to foster expanded research integration within the health sciences disciplines,the University of Michigan Taubman Health Sciences Library established an EXPERT Research Initiative. This new program is part of the strategic planning for the future of the library and is focused on three primary goals： expanding the library＇s research portfolio,building librarians＇ research skills and competencies,and increasing the library＇s research visibility. The article highlights five library projects that illustrate the different kinds of research collaborations librarians are engaged in with health sciences faculty,researchers,clinicians,and students.

关键词： Academic health sciences libraries Collaboration Healthadministration Library research integration Library strategic planning innovation Role of the librariansciences librarians Organizational caseInformationists Librarystudies Organizational

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Evaluation of Size Structure in Freshwater Cyanobacterial Populations: Methods to Quantify Risk Associated with Changes in Biomass and Microcystin Concentrations

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journal of Water Resource and Protection 2019年第6期11卷 810-829页

作者： nancy j. Leland james F. Haney Kristin Conte Karen Malkus-Benjamin Bryan Horsely Lim-Tex North Andover MA USA Department of Zoology University of New Hampshire Durham NH USA Manchester Water Works Manchester NH USA Town of Barnstable Barnstable MA USA Association to Preserve Cape Cod Dennis MA USA

Cyanobacterial populations in surface waters, including drinking water supplies and recreational waters, represent an ever present challenge for resource managers. As communities continuously respond to external and internal processes, dynamic profiles of composition, dominance, growth and toxigenicity emerge. In this study measures of size structure and biomass, quantified using light microscopy and fluorometry, were used to estimate microcystin concentrations through linear regression analysis. Toxigenic profiles using cyanobacterial biomass were developed for lakes dominated by Microcystis spp. and Dolichospermum spp., influenced by both genus-specific pigment concentrations as well as microcystin concentrations. Community composition (Log %MIC) and biomass were used to describe microcystin concentrations in mixed assemblages, where composition was the first input variable. The accessory photopigment phycocyanin was used to describe the linear relationship between the daily growth and net microcystin production rates in the bloom-forming Microcystis spp. samples, suggesting that this size-fractionated sample may provide indications of potential toxigenicity in the whole lake water sample. Future investigations using fluorometric evaluation of cyanobacterial populations could provide additional applications and metrics for use by resource managers to quantify risk association with elevated cyanotoxin concentrations.

关键词： Microcystis Dolichospermum Phycocyanin Microcystins Growth Rates

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Global spatio-temporally harmonised datasets for producing high-resolution gridded population distribution datasets

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Big Earth Data 2019年第2期3卷 108-139页

作者： Christopher T.Lloyd Heather Chamberlain David Kerr Greg Yetman Linda Pistolesi Forrest R.stevens Andrea E.Gaughan jeremiah j.Nieves Graeme Hornby Kytt MacManus Parmanand Sinha Maksym Bondarenko Alessandro Sorichetta Andrew j.Tatem WorldPop School of Geography and Environmental ScienceUniversity of SouthamptonSouthamptonUK Flowminder Foundation StockholmSweden Center for International Earth Science Information Network(CIESIN) Columbia UniversityPalisadesNYUSA Department of Geography and Geosciences University of LouisvilleLouisvilleKYUSA GeoData University of SouthamptonSouthamptonUK

Multi-temporal,globally consistent,high-resolution human population datasets provide consistent and comparable population distributions in support of mapping sub-national heterogeneities in health,wealth,and resource access,and monitoring change in these over *** production of more reliable and spatially detailed population datasets is increasingly necessary due to the importance of improving metrics at sub-national and multitemporal *** is in support of measurement and monitoring of UN Sustainable Development Goals and related *** response to these agendas,a method has been developed to assemble and harmonise a unique,open access,archive of geospatial *** are provided as global,annual time series,where pertinent at the timescale of population analyses and where data is available,for use in the construction of population distribution *** archive includes sub-national census-based population estimates,matched to a geospatial layer denoting administrative unit boundaries,and a number of co-registered gridded geospatial factors that correlate strongly with population presence and ***,we describe these harmonised datasets and their limitations,along with the production ***,we demonstrate applications of the archive by producing multi-temporal gridded population outputs for Africa and using these to derive health and development *** geospatial archive is available at https://***/10.5258/SOTON/WP00650.

关键词： Human population subnational global spatial dataset multi-temporal

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铬铁矿中四面体上亚铁和八面体上三价铁的次近邻效应

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中国科学:化学 1986年第3期 304-310页

作者：李哲,j. G. stevens 中国科学院地质研究所美国北卡路莱纳大学穆斯堡尔效应数据中心北京爱什维尔

本文使用穆斯堡尔谱学研究了四个天然铬铁矿。在所研究的四个铬铁矿中,其中三个铬铁矿的谱被拟合成四面体A位置上三个或四个Fe2+双峰和四面体A和八面体B位置上一个或二个Fe3+双峰。第四个铬铁矿的谱拟合成四面体A位置上一个Fe3+双峰和... 详细信息

本文使用穆斯堡尔谱学研究了四个天然铬铁矿。在所研究的四个铬铁矿中,其中三个铬铁矿的谱被拟合成四面体A位置上三个或四个Fe2+双峰和四面体A和八面体B位置上一个或二个Fe3+双峰。第四个铬铁矿的谱拟合成四面体A位置上一个Fe3+双峰和八面体B位置上二个Fe3+双峰。所得到的四面体A位置上Fe2+离子的同质异能位移为～0.9mm/s,八面体B位置上Fe3+离子的同质异能位移为～0.3mm/s,以及在A位置和B位置上逐渐变化的四极分裂。本文计算出B位置上的二项式分布,并且使用次近邻效应解释了铬铁矿Ⅰ,Ⅱ和Ⅲ中A位置上Fe2+离子和铬铁矿Ⅳ中B位置上Fe3+离子在穆斯堡尔谱中所形成的多重四极双峰。

关键词：铬铁矿尖晶石四面体多面体 Fe 八面体亚铁三价铁

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