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Please join us for the 4th New Horizons in Cancer Research Conference

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Cancer Biology & Medicine 2017年第2期 105-105页

作者： nancy e.davidson Chi Van Dang Kornelia Polyak Hongyang Wang Fred Hutchinson Cancer Center Abramson Cancer Center of University of Pennsylvania Philadelphia Dana Farber Cancer Institute BostonMAUSA

On behalf of the American Association for Cancer Research(AACR),we have the great pleasure to invite you to attend the 4th AACR New Horizons in Cancer Research Conference:Research Propelling Cancer Prevention and Cures,which will be held from November 6-9,2017,in Shanghai,*** year,we are honored that Fudan University will be a partner for the *** outstanding

关键词： AACR MD Ph Please join us for the 4th New Horizons in Cancer Research Conference

Low-loss and polarization insensitive 32×4 optical switch for ROADM applications

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Light(Science & Applications) 2024年第5期13卷 875-884页

作者： Xiaotian Zhu Xiang Wang Yanlu Huang Liyan Wu Chunfei Zhao Mingzhu Xiao Luyi Wang Roy davidson Yanni Ou Brent e.Little Sai T.Chu Department of Physics City University of Hong KongTat Chee AvenueHong KongChina. QXP Technologies Inc. NO.15th Shanglinyuan 1st RoadXi’anShaanxi 710119China. State Key Laboratory of Information of Photonics and Optical Communications School of Electronic EngineeringBeijing University of Posts and TelecommunicationsBeijing 100876China

Integrated switches play a crucial role in the development of reconfigurable optical add-drop multiplexers(ROADMs)that have greater flexibility and compactness,ultimately leading to robust single-chip *** decades of research on switches with various structures and platforms,achieving a balance between dense integration,low insertion loss(IL),and polarization-dependent loss(PDL)remains a significant *** this paper,we propose and demonstrate a 32×4 optical switch using high-index doped silica glass(HDSG)for ROADM *** switch is designed to route any of the 32 inputs to the express ports or drop any channels from 32 inputs to the target 4 drop ports or add any of the 4 ports to any of the 32 express *** switch comprises 188 MachZehnder Interferometer(MZI)type switch elements,88 optical vias for the 44 optical bridges,and 618 waveguidewaveguide crossings with three-dimensional(3D)*** 1550 nm,the fiber-to-fiber loss for each express channel is below 2 dB,and across the C and L bands,below 3 *** each input channel to all 4 drop/add channels at 1550 nm,the loss is less than 3.5 dB and less than 5 dB across the C and L *** PDLs for all express and input channels to the 4 drop/add channels are below 0.3 dB over the C band,and the crosstalk is under−50 dB for both the C and L bands.

关键词： polarization ROADM optical

enhanced electric Power Adaptability Using Hybrid Pumped-Hydro Technology with Wind and Photovoltaic Integration

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energy engineering 2023年第9期120卷 1939-1961页

作者： Uwem O.Ikitde Abayomi A.Adebiyi Innocent e.davidson Ayodeji S.Akinyemi Department of electrical Power engineering Durban University of TechnologyDurban4001South Africa Department of electrical Electronics and Computer EngineeringCape Peninsula University of TechnologyBellville7535South Africa

The integration of solar and wind energy into the electrical grid has received global research attention due to their unpredictable *** wind energy varies across all timescales of utility activity,renewable energy generation should be supplemented and enhanced,from real-time,minute-to-minute variations to annual alterations influencing *** energy generation does not only fluctuate but is also challenging to accurately forecast the timeframes of significance to electricity decision makers;day-ahead and long-term making plans of framework sufficiency such as meeting the network peak load annually.A utility that integrates wind and solar energy into its electricity mix would understand how to adapt to uncertainty and variability in operations while sustaining grid *** to hydropower’s adaptability,a system using hydropower as one of its generating resources could be precisely adapted to absorb the variability of wind and solar *** objective of this research study is to create a hybrid system comprising hydro-wind and solar(Hybrid-HWS)integration for power balancing in an isolated electrical network in Klipkop village,Pretoria region,South *** desirability of designing and building goaf storage tank in regard to capability,the fullness of line throughoutwater pumping,dispensing,storage tank spillage,and pressure difference throughout liquid flow within the storage tanks were preliminary assessed using geotechnical and weather forecasting data from a distinctive area of Klipkop town in Pretoria,South *** facility hours premised on daylight accessibility are scheduled to balance maximum load at early and late ***,in the scenario of electrical power,time shift requiring storage for extended periods of time,such as in terms of hours,Hybrid-HWS has been found to have a crucial *** results of simulations showed a coordinated process design for Hybrid-HWS energy Storage(eS)to determine ev

关键词： Pumped hydro storage(PHS) hybrid hydro-wind-solar technique abandoned coal mine power balancing

Associations of accelerometry-measured and self-reported physical activity and sedentary behavior with skeletal muscle energetics:The Study of Muscle,Mobility and Aging(SOMMA)

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Journal of Sport and Health Science 2024年第5期13卷 621-630页

作者： Yujia(Susanna)Qiao Terri L.Blackwell Peggy M.Cawthon Paul M.Coen Steven R.Cummings Giovanna Distefano Samaneh Farsijani Daniel e.Forman Bret H.Goodpaster Stephen B.Kritchevsky Theresa Mau Frederico G.S.Toledo Anne B.Newman nancy W.Glynn Department of epidemiology School of Public HealthUniversity of PittsburghPittsburghPA 15261USA San Francisco Coordinating Center California Pacific Medical Center Research InstituteSan FranciscoCA 94143USA Department of epidemiology and Biostatistics University of CaliforniaSan FranciscoCA 94143USA Translational Research Institute AdventHealthOrlandoFL 32804USA Department of Medicine(Geriatrics and Cardiology) University of Pittsburghand GeriatricsResearchEducationand Clinical Center(GRECC)VA Pittsburgh Healthcare SystemPittsburghPA 15261USA Department of Internal Medicine Section on Gerontology and Geriatric MedicineWake Forest School of MedicineWinston-SalemNC 27109USA Division of endocrinology and Metabolism Department of MedicineUniversity of PittsburghPittsburghPA 15261USA

Background:Skeletal muscle energetics decline with age,and physical activity(PA)has been shown to offset these declines in older ***,many studies reporting these effects were based on self-reported PA or structured exercise ***,we examined the associations of accelerometry-measured and self-reported PA and sedentary behavior(SB)with skeletal muscle energetics and explored the extent to which PA and sedentary behavior would attenuate the associations of age with muscle ***:As part of the Study of Muscle,Mobility and Aging,enrolled older adults(n=879),810(age=76.4±5.0 years old,mean±SD;58%women)had maximal muscle oxidative capacity measured ex vivo via high-resolution re spirometry of permeabilized myofibers(maximal oxidative phosphorylation(maxOXPHOS))and in vivo by ^(31)phosphorus magnetic resonance spectroscopy(maximal adenosine triphosphate(ATP_(max))).Accelerometry-measured sedentary behavior,light activity,and moderate-to-vigorous PA(MVPA)were assessed using a wrist-worn ActiGraph GT9X over 7 ***-reported sedentary behavior,MVPA,and all PA were assessed with the Community Healthy Activities Model Program for Seniors(CHAMPS)*** regression models with progressive covariate adjustments evaluated the associations of sedentary behavior and PA with muscle energetics,as well as the attenuation of the age/muscle energetics association by MVP A and sedentary *** a sensitivity analysis,we also examined activPAL-measured daily step count and time spent in sedentary behavior and their associations with muscle ***:every 30 min/day more of ActiGraph-measured MVPA was associated with 0.65 pmol/(s×mg)higher maxOXPHOS and 0.012 mM/s higher ATP_(max)after adjusting for age,site/technician,and sex(ped with maxOXPHOS or ATP_(max).Meanwhile,every 30 min/day spent in ActiGraph-measured sedentary behavior was associated with 0.39 pmol/s×mg lower maxOXPHOS and0.

关键词： Aging exercise Mitochondria

DOWNSTReAM DeVeLOPMeNT DURING THe eXTRATROPICAL TRANSITION OF TROPICAL CYCLONeS:OBSeRVATIONAL eVIDeNCe AND INFLUeNCe ON STORM STRUCTURe

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Tropical Cyclone Research and Review 2012年第4期1卷 430-447页

作者： LILI LIU NOeL e.davidson HONGYAN ZHU CHARLIe C.F.LOK Centre for Australian Weather and Climate Research A partnership between CSIRO and the Bureau of MeteorologyMelbourneAustralia Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100029China Graduate University of Chinese Academy of SciencesBeijing 100049China

Observational evidence is presented that during extratropical Transition(eT) of Tropical Cyclones(TCs),Downstream Development(DD) is frequently *** show that DD results in rapid changes to the environment.A critical flow change is the development of a low-level trough,sandwiched between two developing *** trough appears to merge with the storm,seemingly holding it upright and allowing it to withstand the damaging effects of wind *** this way the storm can eventually reach the favourable equatorward entrance region of the upper *** evaluate the mechanism,two sets of simulations have been run:one using high-resolution,full physics integrations and another using coarse-resolution with dry physics and the TC removed from the initial *** show that the dry dynamics can establish the large scale environment to enable the transition to *** process can produce:(a) the deep,vertically-aligned,low-level pressure trough that merges with the storm,and(b) a partial inhibition through subsidence to embedded convection,allowing the boundary layer to moisten via(i) sustained surface fluxes,and(ii) enhanced horizontal moisture flux convergence from the environmental flow *** produces potential for more intense convective activity and vortex resiliency even in relatively strong,deep vertical wind shear.

关键词： Observational evidence extratropical Transition Tropical Cyclones

Bio-economic Strategy to Combat Non-Point Pollution in China

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Pedosphere 2005年第2期15卷 156-163页

作者： B. davidson R.e.WHITe Institute of Land and Food Resources Institute of Land and Food Resources The University of MelbourneParkville Victoria 3010 (Australia)The University of MelbourneParkville Victoria 3010 (Australia)

While non-point pollution from agriculture has become an increasingly serious problem in China, some progress has been made in studying the causal biophysical processes. However, few studies have assessed the economic consequences of non-point pollution in China or the policy options that could be employed to combat it. In this work a sustainable strategy to control non-point pollution from crop production, which involved taxing excessive inputs of irrigation water and fertilizer, was proposed. The approach taken to assess these measures combined biophysical and economic models,having a trade-off between economic returns and an improved environment. A proven and practical spatially referenced water and nutrient management model was used to determine the quantities of excessive irrigation water and fertilizer for specific soil and land use. Also, a set of indicators were proposed for evaluating the effects of agricultural economic output and agricultural practices on the environment.

关键词： crop production integrated biophysical-economic model non-point pollution policy instrument sustainable strategy

OBJeCTIVe eSTIMATION OF THe RADIUS OF THe OUTeRMOST CLOSeD ISOBAR IN TROPICAL CYCLONeS

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Tropical Cyclone Research and Review 2014年第1期3卷 1-21页

作者： HARRY C.WeBeR CHARLIe C.F.LOK NOeL e.davidson YI XIAO Fachhochschule des Bundes für offentliche Verwaltung Fachbereich WetterdienstFürstenfeldbruckGermany Centre for Australian Weather and Climate Research A partnership between the Australian Bureau of Meteorology and CSIROMelbourneAustralia

Increased understanding of the importance of TC structure in dynamical,climatological and prediction studies makes determination of TC size important. A new algorithm for the objective estimation of the radius of outermost closed isobar(roci) has been developed. The new method uses storm position and global analyses of mean sea level pressure to compute a mean(axisymmetric) roci. This radius can be used,together with the central pressure,for the construction of a synthetic vortex that is initialized in a numerical prediction model. The method also has important applications in dynamical and climatological studies of TC intensity,size and structure. The algorithm is robust and capable of estimating roci,even in the case of a weak system that may not have a closed isobar in the global analysis. The values produced by the new method are shown to be more consistent than the corresponding operational estimates which are subjective and produced under strong time constraints. Statistical comparison between subjective and objective estimates gives a mean absolute difference of 110 km,which given the difficulty in making a subjective estimate,is satisfactory. In addition,even though limitations exist with the estimates of vortex parameters like the radius to gales(r34),comparison with estimates from an extended best track data set provides independent evaluation of the scheme. Mean absolute difference for r34 for around 3200 cases is near 80 km,even though the best track estimates are subjective and the objective r34 is estimated only from storm central pressure and the objective roci. This validation suggests that the algorithm can be used to obtain useful size estimates of TCs.

关键词： tropical cyclone size estimation

Synthesis of a copper(Ⅱ) oxide–montmorillonite composite for lead removal

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International Journal of Minerals,Metallurgy and Materials 2019年第7期26卷 803-810页

作者： davidson e. egirani Nanfe R. Poyi Napoleon Wessey Faculty of Science Niger Delta University Wilberforce Island Nigeria Nigerian Institute of Mining and Geosciences Jos Nigeria

The synthesis of a copper(II) oxide–montmorillonite composite and its application in the removal of lead(II) ions in solution were investigated. The Acros Organics (ACOR) montmorillonite was activated using potassium hydroxide solution. The activated ACOR montmorillonite was titrated with copper(II) nitrate solution to produce the copper(II) oxide–montmorillonite composite. Adsorption experiments were conducted using batch-mode techniques under reducing conditions at ambient temperature. The reaction mechanism indicated a higher proton coefficient, greater intraparticle diffusion, and higher mass transfer rates compared with those achieved with bare montmorillonite. The intraparticle diffusion constant derived from the slope was 2.93^-3 (mg·g^–1·min^–0.5), and the intercept C was 9.86,≠ 0. In the presence of a CuO coating, the adsorption efficiency was 85.55% at pH 4 and 89.62% at pH 7. Therefore, the copper(II) oxide-montmorillonite composite, as a novel adsorbent with a very high adsorption capacity, exhibited substantially enhanced adsorption of Pb^2+ ions compared with bare montmorillonite.

关键词： activation adsorption kinetics aging coatings copper oxide montmorillonite

Analysis of an ensemble of High-Resolution WRF Simulations for the Rapid Intensification of Super Typhoon Rammasun(2014)

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Advances in Atmospheric Sciences 2020年第2期37卷 187-210页

作者： Xun LI Noel edavidson Yihong DUAN Kevin JTORY Zhian SUN Qinbo CAI Key Laboratory of South China Sea Meteorological Disaster Prevention and Mitigation of Hainan Province China Meteorological AdministrationHaikouHainan 570203China Hainan Meteorological Services China Meteorological AdministrationHaikouHainan 570203China Research and Development Branch Bureau of MeteorologyMelbourne 3001Australia State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China

Diagnostics are presented from an ensemble of high-resolution forecasts that differed markedly in their predictions of the rapid intensification(RI)of Typhoon *** show that the basic difference stems from subtle differences in initializations of(a)500-850-h Pa environmental winds,and(b)midlevel moisture and *** then describe how these differences impact on the evolving convective organization,storm structure,and the timing of *** expected,ascent,diabatic heating and the secondary circulation near the inner-core are much stronger in the member that best forecasts the *** evolution of vortex cloudiness from this member is similar to the actual imagery,with the development of an inner cloud band wrapping inwards to form the *** present evidence that this structure,and hence the enhanced diabatic heating,is related to the tilt and associated dynamics of the developing inner-core in *** the most accurate ensemble member:(a)inhibition of ascent and a reduction in convection over the up-shear sector allow moistening of the boundary-layer air,which is transported to the down-shear sector to feed a developing convective asymmetry;(b)with minimal ventilation,undiluted clouds and moisture from the down-shear left quadrant are then wrapped inwards to the up-shear left quadrant to form the eyewall cloud;and(c)this process seems related to a critical down-shear tilt of the vortex from midlevels,and the vertical phase-locking of the circulation over up-shear *** the member that forecasts a much-delayed RI,these processes are inhibited by stronger vertical wind shear,initially resulting in poor vertical coherence of the circulation,lesser moisture and larger *** analysis suggests that ensemble prediction is needed to account for the sensitivity of forecasts to a relatively narrow range of environmental wind shear,moisture and vortex inner-structure.

关键词： typhoons rapid intensification ensemble simulation spin-up processes ventilation vertical wind shear