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中俄边境地区外贸企业资本分布的影响因素及尺度效应

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经济地理 2024年第2期44卷 102-111页

作者：李雨欣张平宇杨奇峰初楠臣中国科学院东北地理与农业生态研究所吉林长春130102 中国科学院大学资源与环境学院北京100049 哈尔滨师范大学地理科学学院黑龙江哈尔滨150025

文章以中国东北的中俄边境地区为案例区域,基于县域单元从微观视角刻画了外贸企业资本分布的时空演变特征,并构建空间计量模型、MGWR模型重点探讨了不同因素对外贸企业资本分布的作用程度及尺度效应。结果表明:①2011—2021年中俄边境... 详细信息

文章以中国东北的中俄边境地区为案例区域,基于县域单元从微观视角刻画了外贸企业资本分布的时空演变特征,并构建空间计量模型、MGWR模型重点探讨了不同因素对外贸企业资本分布的作用程度及尺度效应。结果表明:①2011—2021年中俄边境地区外贸企业的资本规模呈现先快速增长后缓慢下降的变化趋势。其中批发零售企业和制造企业的资本规模始终最高,但在俄远东地区市场环境的冲击下,二者增长率自2015年开始逐渐下滑。②外贸企业的资本规模在2011—2021年呈现整体集聚、局部扩散的演变格局,并表现出多核心的结构形态。其中批发零售企业的路径依赖特征显著,呈现极化发展的沿边分布模式;制造企业则不断向内陆地区扩张,形成“沿边—腹地”产业协同态势。③从“全球—地方”视角来看,边境地区对国际地缘形势、国内开放政策和地区发展禀赋高度敏感。其中与外贸企业活力直接相关的微观变量作用尺度更小,与企业所处经济环境相关的宏观变量作用尺度更大。④不同类型企业资本布局具有独特的区位、政策和环境偏好。其中批发零售企业具有较强的市场敏感性和资本活跃性,因此企业资本根植于地区开放程度、市场潜力以及融资能力;制造企业的资本分布受产业集聚和制度性力量的驱动,工业基础、第二产业及交通条件的影响十分显著。

关键词：外贸企业资本分布尺度效应 MGWR模型中俄边境

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中国东北与俄罗斯远东地区产业合作发展研究

经济研究导刊 2024年第3期 20-24页

作者：王成初楠臣北京市规划和自然资源委员会延庆分局北京102100 哈尔滨师范大学地理科学学院哈尔滨150025

中俄双边是最亲密的友好伙伴,中国东北地区与俄罗斯远东地区的产业发展合作由来已久。在“一带一路”和“中蒙俄经济走廊”倡议下,在俄乌战争的背景下,研究中国东北和俄罗斯远东地区的产业发展具有重要意义。从农业、工业、服务业的视... 详细信息

中俄双边是最亲密的友好伙伴,中国东北地区与俄罗斯远东地区的产业发展合作由来已久。在“一带一路”和“中蒙俄经济走廊”倡议下,在俄乌战争的背景下,研究中国东北和俄罗斯远东地区的产业发展具有重要意义。从农业、工业、服务业的视角出发,分析中国东北地区与俄罗斯远东地区农业、工业、服务业发展合作的现状、问题、对策,以期为未来中俄双边产业合作与可持续发展提供借鉴与启示,助推中国东北地区经济的再次振兴与腾飞。

关键词：产业合作发展中国东北地区俄罗斯远东地区

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Transnational Economic Connection Analysis Based on Railway Class Accessibility Between China and Russia

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Chinese Geographical Science 2019年第5期29卷 872-886页

作者： CHU nanchen ZHANG Pingyu LI He Northeast Institute of Geography and Agroecology Chinese Academy SciencesChangchun130102China College of Resources and Environment University of Chinese Academy of SciencesBeijing100049China

Under the background of ‘the Belt and Road’ initiative, the economic cooperation has great potential between China and Russia. The railway accessibility has an important influence on the economic connections of cities along the railway line. This paper studied the Sino-Russian transnational economic connection based on the railway class accessibility along Trans-Siberian railway(the transnational China railway branch line). The results are as following. First, the railway accessibility of the Chinese nodes is stronger than that of the Russian nodes, which in general displays a tendency of space attenuation from China to the Sino-Russian border, then to Russia. Spatially, the railway accessibility within the study area shows a ‘High East, Low West’ and ‘High South, Low North’ spatial pattern. The railway accessibility of the nodes, which are located at the beginning and end of the railway line, is weaker than those nodes located in the middle of the line. Second, the railway accessibility and external economic connection intensity summation of the nodes show a positive relationship along the railway line. The economic connection intensity summation of different nodes presents obvious regional differentiation. Finally, as economic connection network has evolved, the small world effect of Sino-Russian railway economic connection network becomes strong.

关键词： railway class accessibility economic connection intensity spatial pattern China Russia

2010—2020年江苏省旅游发展水平测度与时空格局分析

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科技创新与生产力 2024年第5期45卷 15-19,23页

作者：姚宇鸿初楠臣姜奇哈尔滨师范大学地理科学学院黑龙江哈尔滨150025 哈尔滨师范大学财务处黑龙江哈尔滨150025

本文指出在“十四五”旅游业发展规划背景下,研究江苏省旅游发展水平具有重要意义。本文以江苏省为研究对象,构建江苏省旅游发展水平评价指标体系,结合熵值赋权法和变异系数赋权法测算江苏省2010—2020年旅游发展水平,并利用ArcGIS模拟... 详细信息

本文指出在“十四五”旅游业发展规划背景下,研究江苏省旅游发展水平具有重要意义。本文以江苏省为研究对象,构建江苏省旅游发展水平评价指标体系,结合熵值赋权法和变异系数赋权法测算江苏省2010—2020年旅游发展水平,并利用ArcGIS模拟其时空格局。研究表明:2010—2020年江苏省旅游综合、经济、人口、基础设施发展水平时间上呈现波动变化的趋势,其中江苏省旅游综合、经济、人口发展水平表现出“上升—下降—上升—下降”的变化特征,江苏省旅游基础设施发展水平表现出“上升—下降”的变化特征;空间上,江苏省旅游综合、经济、人口、基础设施发展水平均呈现出“南高北低”的分布格局,苏南地区旅游综合、经济、人口、基础设施发展水平均高于苏北地区、苏中地区,南京市、苏州市旅游综合、经济、人口、基础设施发展水平高于其他地级市。

关键词：旅游发展水平时空格局评价指标体系熵值赋权法变异系数赋权法江苏

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Role of adhesion molecules and dendritic cells in rat hepatic/renal ischemia-reperfusion injury and anti-adhesive intervention with anti-P-selectin lectin-EGF domain monoclonal antibody

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World Journal of Gastroenterology 2005年第7期11卷 1005-1010页

作者： TongZhou Gui-ZhiSun Ming-JunZhang Jin-LianChen Dong-QingZhang Qing-ShenHu Yu-YingChen nanchen DepartmentofNephrology RuiJinHospitalShanghaiSecondMedicalUniversityShanghai200025China AnimalLaboratory RuiJinHospitalShanghaiSecondMedicalUniversityShanghai200025China DepartmentofGastroenterology ShanghaiSixthPeople'sHospitalShanghai200233China ShanghaiInstituteofImmunology ShanghaiSecondMedicalUniversityShanghai200025China InstituteofCellularBiology ShanghaiSecondMedicalUniversityShanghai200025China

AIM: To investigate the role of P-selectin, intercellular adhesion molecule-1 (ICAM-1) and dendritic cells (DCs)in liver/kidney of rats with hepatic/renal ischemiareperfusion injury and the preventive effect of anti-Pselectin lectin-EGF domain monoclonal antibody (anti-PsLEGFmAb) on the ***: Rat models of hepatic and renal ischemiareperfusion were established. The rats were then divided into two groups, one group treated with anti-PsL-EGFmAb(n = 20) and control treated with saline (n = 20). Both groups were subdivided into four groups according to reperfusion time (1, 3, 6 and 24 h). The sham-operated group (n = 5) served as a control group. DCs were observed by the microscopic image method, while P-selectin and ICAM-1 were analyzed by ***: P-selectin increased significantly in hepatic sinusoidal endothelial cells and renal tubular epithelial cells 1 h after ischemia-reperfusion, and the expression of ICAM-1 was up-regulated in hepatic sinusoid and renal vessels after 6 h. CD1a+CD80+DCs gradually increased in hepatic sinusoidal endothelium and renal tubules and interstitium 1 h after ischemia-reperfusion, and there was the most number of DCs in 24-h group. The localization of DCs was associated with rat hepatic/renal *** changes became less significant in rats treated with ***: DCs play an important role in immune pathogenesis of hepatic/renal ischemia-reperfusion ***-PsL-EGFmAb may regulate and inhibit local DC immigration and accumulation in liver/kidney.

关键词： Adhesion molecules Dendritic cells Hepatic/ renal ischemia-reperfusion injury Anti-P-selectin lectinEGF domain monoclonal antibody

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江苏省交通与经济发展耦合协调性分析

科技创新与生产力 2024年第4期45卷 67-70页

作者：赵子欣姜奇王浩然初楠臣哈尔滨师范大学地理科学学院黑龙江哈尔滨150025 哈尔滨师范大学财务处黑龙江哈尔滨150025

本文运用熵权法和变异系数赋权法,构建江苏省交通与经济发展水平体系,运用耦合协调模型对2013—2020年江苏省交通与经济的相互影响程度进行测度。研究表明:2013—2020年江苏省交通与经济耦合度整体偏高,处于磨合阶段与高水平耦合阶段,... 详细信息

本文运用熵权法和变异系数赋权法,构建江苏省交通与经济发展水平体系,运用耦合协调模型对2013—2020年江苏省交通与经济的相互影响程度进行测度。研究表明:2013—2020年江苏省交通与经济耦合度整体偏高,处于磨合阶段与高水平耦合阶段,城市交通与经济发展处于高水平平衡状态。江苏省交通与经济协调发展度呈现提升的趋势,苏南地区交通与经济的协调发展度明显高于苏北和苏中地区,进而呈现“南高北低”的格局特征。

关键词：交通发展经济发展耦合协调度江苏

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Prokaryotic expression and renaturation of engineering chimeric Fab antibody against human hepatoma

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World Journal of Gastroenterology 2004年第14期10卷 2029-2033页

作者： Jin-LiangXing Xiang-MinYang Xi-YingYao FeiSong Zhi-nanchen CellEngineeringResearchCenter FacultyofPreclinicalMedicineFourthMilitaryMedicalUniversityXi'an710032ShaanxiProvinceChina CellEngineeringResearchCenter FacultyofPreclinicalMedicineFourthMilitaryMedicalUniversityXi'an710032ShaanxiProvinceChina

AIM: To express chimeric Fd (cFd) and chimeric light chain (cL) in *** respectively and refold them into chimeric Fab (cFab) ***: cFd and cL genes were respectively inserted into the prokaryotic expression vector pET32a to construct recombinant vectors pET32a/cFd and pET32a/cL. Then,the competent *** cells were transformed by the recombinant vectors and induced by IPTG. Moreover, a large quantity of cFd and cL expression products were prepared and mixed with equal molar to refold into cFab by gradient dialysis. The refolded products were identified and analyzed by sodium SDS-PAGE, Western blotting,ELISA and ***: High efficient prokaryotic expressions of both cFd and cL in the form of non-fusion protein were obtained with the expression levels of 28.3% and 32.3% of total bacteria proteins, respectively. Their relative molecular masses were all 24 ku or so, and both of them mainly existed in the form of inclusion bodies. In addition, cFd and cL were successfully refolded into cFab by gradient dialysis, with about 59.45% of recovery when the starting total protein concentration was 100 μg/mL. The renatured cFab could specifically bind to related antigen with high ***: The cFab antibody against human hepatoma was highly and efficiently expressed and refolded, which laid a solid foundation for studying its application in the treatment of hepatoma.

关键词：原核表达 Fab抗体肝细胞瘤肿瘤 cL

Establishment and characterization of human hepatocellular carcinoma cell line FHCC-98

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World Journal of Gastroenterology 2004年第10期10卷 1462-1465页

作者： Chao-YangLou Ying-MingFeng Ai-RongQian YuLi HaoTang PengShang Zhi-nanchen DepartmentofOncology TangduHospitalFourthMilitaryMedicalUniversityXi'an710038ShaanxiProvinceChina DepartmentofCellBiology FourthMilitaryMedicalUniversityXi'an710032ShaanxiProvinceChina

AIM: To establish a novel human hepatocellular carcinoma (HCC) cell line FHCC-98 from HCC tissue and to provide a suitable model for studying HCC occurrence, progress and ***: Serially passaged cells were cultured and their morphologies were observed under light and electron microscope. Cytogenetic study was conducted by using flow cytometry and chromosome analysis. Expressions of tumor markers such as α-fetoprotein (AFP), cytokeratin (CK) and hepatoma metastasis-associated factor HAb18G/CD147 on the FHCC-98 cells were detected by immunocytochemistry or Western blotting. Lactic dehydrogenase (LDH) isoenzymes were detected by polyacrylamide gel electrophoresis (PAGE).Xenograft was performed by inoculating FHCC-98 cells into the flanks of nude ***: Morphology of FHCC-98 cells was the same as that of other malignant cells. The expressions of the cells were positive for HAb18G/CD147 and CK, and negative for AFP. Its population doubling time was 21.4 h. The cell DNA was tetraploid and the major chromosomes were triploid by cytogenetics analysis. The tumorigenicity in nude mice was 100%. PAGE showed four bands representing LDH2, LDH3,LDH4 and ***: FHCC-98 is a novel HCC cell line and an ideal cell model for further exploring the mechanism of hepatocellular carcinoma invasion and metastasis.

关键词： FHCC-98细胞肝细胞癌预后肿瘤转移肿瘤生物学

数字贸易规则与中国制度型开放:未来向度和现实进路

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中国特色社会主义研究 2022年第2期 31-41页

作者：刘斌崔楠晨对外经济贸易大学国家对外开放研究院对外经济贸易大学中国WTO研究院

数字贸易规则不仅是国际经贸规则重构的焦点议题,也是中国推进制度型开放的重要抓手。未来全球数字贸易规则将呈现大国主导、区域割据等特征。当前中国的数字贸易治理仍然面临着贸易壁垒较高、制度建设滞后于实践等问题。中国通过对标... 详细信息

数字贸易规则不仅是国际经贸规则重构的焦点议题,也是中国推进制度型开放的重要抓手。未来全球数字贸易规则将呈现大国主导、区域割据等特征。当前中国的数字贸易治理仍然面临着贸易壁垒较高、制度建设滞后于实践等问题。中国通过对标《全面与进步跨太平洋伙伴关系协定》和《数字经济伙伴关系协定》中高标准的数字贸易规则,正主动融入全球数字贸易治理体系。在开放的过程中,中国应正确处理安全与开放、对接性开放与主动性开放、产业开放与数据开放这三对关系。针对接受难度较大的条款,对外要释放明确的政策预期,对内要夯实促进数字贸易发展的制度性安排;针对接受难度较小的条款,主动对接国际高标准数字贸易规则,在先行先试和复制推广中明确开放的范围与程度,形成和输出数字贸易治理的“中式模板”,从而提升中国在国际数字贸易规则制定中的话语权。

关键词：数字贸易规则制度型开放未来向度现实进路