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Mechanism of Ag and Al on improving the glass forming ability of CuZr-based alloys

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International Journal of Minerals,Metallurgy and Materials 2011年第4期18卷 424-429页

作者： Xiao-dong Ni Zheng Wang xiang Sun Jiang Shen nan-xian chen School of Applied Science University of Science and Technology Beijing Beijing 100083 China Department of Physics Tsinghua University Beijing 100084 China

By a mean field theoretical computation,the equilibrium distributions of additional Ag and Al in the crystalline phase of CuZr-based alloys were determined to occupy the two sublattices of the B2 structure *** the molecular dynamics technique,the effects of Ag and Al on the enthalpy difference（ΔH） between the supercooled melt and the crystalline phase were *** improved glass forming ability of Cu45Zr45Al10 and Cu45Zr45Ag10 can be attributed to their remarkably smaller ΔH than that of *** calculated diffusion coefficients are more sensitive to the atomic weight of the component atoms than to their interaction *** the component atom with the largest mass,the additional Ag increases the viscosity of the supercooled melt significantly and the experimentally stronger glass formation ability of Cu45Zr45Ag10 than Cu45Zr45Al10 can be well understood.

关键词： metallic glass ternary systems computer simulation glass forming ability atomistic simulation site occupancy

Track correlation algorithm based on CNN-LSTM for swarm targets

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Journal of Systems Engineering and Electronics 2024年第2期35卷 417-429页

作者： chen Jinyang WANG Xuhua chen xian Research Institute for National Defense Engineering Academy of Military SciencesLuoyang 471023China Information Engineering University Zhengzhou 450001China School of Computer Science and Technology Xidian UniversityXi’an 710071China

The rapid development of unmanned aerial vehicle(UAV) swarm, a new type of aerial threat target, has brought great pressure to the air defense early warning system. At present, most of the track correlation algorithms only use part of the target location, speed, and other information for *** this paper, the artificial neural network method is used to establish the corresponding intelligent track correlation model and method according to the characteristics of swarm ***, a route correlation method based on convolutional neural networks (CNN) and long short-term memory (LSTM)Neural network is designed. In this model, the CNN is used to extract the formation characteristics of UAV swarm and the spatial position characteristics of single UAV track in the formation,while the LSTM is used to extract the time characteristics of UAV swarm. Experimental results show that compared with the traditional algorithms, the algorithm based on CNN-LSTM neural network can make full use of multiple feature information of the target, and has better robustness and accuracy for swarm targets.

关键词： track correlation correlation accuracy rate swarm target convolutional neural network(CNN) long short-term memory(LSTM)neural network

A Scalable Pillar Layered Metal-Organic Framework for Natural Gas Purification

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Chemical Research in Chinese Universities 2024年第4期40卷 675-681页

作者： LU nan LAN Lan GAO Qiang LI Na BU xian-He School of Materials Science and Engineering Nankai UniversityTianjin300350P.R.China State Key Laboratory of Elemento-Organic Chemistry College of ChemistryNankai UniversityTianjin300071P.R.China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang212003P.R.China

One-step harvest of high-purity methane(CH_(4))from ternary propane/ethane/methane(C_(3)H_(8)/C_(2)H_(6)/CH_(4))mixtures remains a desirable yet challenging goal for natural gas ***,adsorbents either suffer from high capacity and selectivity,or are caught in a dilemma of scalable ***,we demonstrate a scalable pillar layered metal-organic framework Ni-MOF for highly efficient one-step CH_(4)***-MOF exhibits high C_(2)H_(6)and C_(3)H_(8)uptakes of 83.3 and 86.1 cm^(3)/g at 298 K and 100 kPa and remarkable C_(2)H_(6)/CH_(4)(50/50,volume ratio,21.5)and C_(3)H_(8)/CH_(4)(50/50,volume ratio,212.0)***,high C_(2)H_(6)(42.2 cm^(3)/g at 10 kPa)and C_(3)H_(8)(64.7 cm^(3)/g at 5 kPa)capacities in the low-pressure region at 298 K were realized on Ni-MOF,suggesting the strong affinities of Ni-MOF towards C_(2)H_(6)and C_(3)H_(8).Furthermore,the dynamic breakthrough experiments revealed that purifying CH_(4)from natural gas in one-step can be achieved in Ni-MOF with high-purity(>99.8%)and productivity(346.0 cm^(3)/g).Most significantly,the production of Ni-MOF can be scalably synthesized at room temperature,rendering it promising potential for industrial *** combined advantages of exceptional separation performance,scalability,and cycle stability of Ni-MOF pave the way for one-step CH_(4)purification from natural gas.

关键词： Metal-organic framework Adsorption and separation Natural gas purification Scale-up synthesis

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全身炎症反应综合征理论与病毒感染性疾病

中华儿科杂志 2010年第2期48卷 87-89页

作者：陈贤楠首都医科大学附属北京儿童医院ICU 100045

近几十年来，麻疹病毒、腺病毒、SARS、禽流感、肠道病毒71型（EV71）、H1N1等病毒感染性疾病在国内及国际上均发生过较大的流行。当前，我国仍有EV71感染所致手足口病流行，H1N1甲型流感已进入流行高峰期。尽管防治工作取得不少成绩，... 详细信息

近几十年来，麻疹病毒、腺病毒、SARS、禽流感、肠道病毒71型（EV71）、H1N1等病毒感染性疾病在国内及国际上均发生过较大的流行。当前，我国仍有EV71感染所致手足口病流行，H1N1甲型流感已进入流行高峰期。尽管防治工作取得不少成绩，但是，不论从医学理论，还是实践的角度看，仍存在不少问题和困惑。

关键词：病毒感染性疾病全身炎症反应综合征肠道病毒71型 H1N1 麻疹病毒 SARS 手足口病 EV71

Realgar-indigo naturalis formula for the treatment of patients with relapsed and arsenic trioxide-resistant acute promyelocytic leukemia:A case series

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Journal of Integrative Medicine 2024年第5期22卷 614-620页

作者： Yong-guang Fang Shi-lin Huang nan-nan chen Department of Hematology PLA 967th Hospital

Introduction: There is currently no standard treatment for relapsed and arsenic trioxide(ATO)-resistant acute promyelocytic leukemia(APL). Here, we report a case series of realgar-indigo naturalis formula(RIF) for the successful treatment of patients with relapsed and ATO-resistant *** presentation: Two patients in the first relapse and one in the second relapse failed to achieve hematologic complete remission(HCR) when reinduced by ATO; the other five patients progressed to relapse during ATO-based regimens for post-remission therapy. These eight patients received RIF in three doses per day totaling 130 mg/kg(≤ 30 pills) as induction therapy and achieved HCR at a median time of46.5 days. They received 5 years of post-remission therapy, which consisted of combined chemotherapy followed by RIF. During this period, the patients did not experience renal dysfunction or QT interval prolongation. At the last follow-up, three patients survived without relapse, two patients survived with a second or third relapse and third or fourth remission, and the other three patients relapsed for a third or fourth time and died. The 5-year overall survival and event-free survival rates were 75.0%(95% confidence interval [CI]: 31.5–93.1) and 37.5%(95% CI: 5.6–71.7), ***: RIF for induction therapy and RIF combined with chemotherapy for post-remission therapy may represent an effective and safe protocol for the treatment of patients with relapsed and ATO-resistant APL.

关键词： Acute promyelocytic leukemia Realgar-indigo naturalis formula Arsenic Trioxide Resistant Case report

An improved high-fidelity adaptive model for integrated inlet-engine-nozzle based on mechanismdata fusion

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Chinese Journal of Aeronautics 2024年第8期37卷 190-207页

作者： chen WANG Ziyang YU xian DU Ximing SUN School of Control Science and Engineering Dalian University of TechnologyDalian 116024China Key Laboratory of Intelligent Control and Optimization for Industrial Equipment Ministry of EducationDalian University of TechnologyDalian 116024China

Nowadays,there has been an increasing focus on integrated flight propulsion control and the inlet-exhaust design for the aero-propulsion *** component-level models are inadequate due to installed performance deviations and mismatches between the real engine and the model,failing to meet the accuracy requirements of supersonic *** paper establishes a quasi-one-dimensional model for the inlet-exhaust system and conducts experimental ***,a mechanism-data fusion adaptive modeling scheme using an Extreme Learning Machine based on the Salp Swarm Algorithm(SSA-ELM)is *** study reveals the inlet model’s efficacy in reflecting installed performance,flow matching,and mitigating pressure distortion,while the nozzle model accurately predicts flow coefficients and thrust coefficients,and identifies various operational *** model’s output closely aligns with typical experimental *** combining offline optimization and online adaptive correction,the mechanismdata fusion adaptive model substantially reduces output errors during regular flights and varying levels of degradation,and effectively handles gradual degradation within a single flight ***,the mechanism-data fusion adaptive model holistically addresses total pressure errors within the inlet-exhaust system and normal shock location *** approach significantly curbs performance deviations in supersonic *** example,at Ma=2.0,the system error impressively drops from 34.17%to merely 6.54%,while errors for other flight conditions consistently stay below the 2.95%*** findings underscore the clear superiority of the proposed method.

关键词： Aero-propulsion system Integrated inlet-enginenozzle Component-level model On-board adaptive model Mechanism-data fusion Extreme learning machine

Tailoring microenvironment for efficient CO_(2)electroreduction through nanoconfinement strategy

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nano Research 2024年第9期17卷 7880-7899页

作者： Lulu chen Minhan Li Jia-nan Zhang Key Laboratory of Advanced Energy Catalytic and Functional Materials Preparation Country College of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001China

The electrocatalytic conversion of CO_(2)to produce fuels and chemicals holds great promise,not only to provide an alternative to fossil feedstocks,but also to use renewable electricity to convert and recycle the greenhouse gas CO_(2)to mitigate climate ***,the selectivity and reaction rates for the conversion of CO_(2)into desirable carbon-based products,especially multicarbon products with high added value,are still insufficient for commercial applications,which is attributed to insufficiently favourable microenvironmental conditions in the vicinity of the *** construction of catalysts/electrodes with confined structures can effectively improve the reaction microenvironment in the vicinity of the electrodes and thus effectively direct the reaction towards the desired *** this review,we firstly introduce the effects of the microenvironment at the electrode-electrolyte interface including local pH,local intermediate concentration,and local cation concentration on CO_(2)reduction reaction(CO_(2)RR)as well as the mechanism of action,and then shed light on the microenvironmental modulation within the confined space,and finally and most importantly,introduce the design strategy of CO_(2)RR catalyst/electrode based on the confinement effect.

关键词： CO_(2)reduction reaction microenvironment confinement effect catalyst design

Spin-orbit interaction induced Casimir-Lifshitz torque between two-dimensional electron gases

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Science China(Physics,Mechanics & Astronomy) 2024年第8期67卷 134-142页

作者： Jia-nan Rong Liang chen Kai Chang State Key Laboratory of Superlattices and Microstructures Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China School of Mathematics and Physics North China Electric Power UniversityBeijing 102206China School of Physics Zhejiang UniversityHangzhou 310027China College of Materials Science and Opto-electronic Technology University of Chinese Academy of SciencesBeijing 100049China

We investigate theoretically the Casimir interaction between two parallel two-dimensional electron gases(2DEGs)with Rashba and Dresselhaus spin-orbit interactions(SOIs),based on the quantum field *** derive an analytical expression for the polarization tensor and obtain the solution to the motion equation of the electromagnetic(EM)*** calculate the CasimirLifshitz torque(CLT)between two parallel 2DEGs with Rashba and Dresselhaus SOIs,which can be tuned by changing the relative strength between two *** anisotropic Casimir energy between 2DEGs caused by the interplay between the SOIs of 2DEGs offers a new origin of CLT and a new type of optoelectronic device.

关键词： Casimir torque two-dimensional electron gas spin-orbit interaction

Genetic regulation of m^(6)A RNA methylation and its contribution in human complex diseases

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Science China(Life Sciences) 2024年第8期67卷 1591-1600页

作者： Kexuan chen Jiuhong nan Xushen Xiong The Second Affiliated Hospital&Liangzhu Laboratory Zhejiang University School of MedicineHangzhou 311121China State Key Laboratory of Transvascular Implantation Devices The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 311121China

N6-methyladenosine(m^(6)A)has been established as the most prevalent chemical modification in message RNA(mRNA),playing an essential role in determining the fate of RNA *** of m^(6)A has been revealed to lead to abnormal physiological conditions and cause various types of human *** studies have delineated the genetic regulatory maps for m^(6)A methylation by mapping the quantitative trait loci of m^(6)A(m^(6)A-QTLs),thereby building up the regulatory circuits linking genetic variants,m^(6)A,and human complex ***,we review the recent discoveries concerning the genetic regulatory maps of m^(6)A,describing the methodological and technical details of m^(6)A-QTL identification,and introducing the key findings of the cis-and trans-acting drivers of m^(6)*** further delve into the tissue-and ethnicity-specificity of m^(6)A-QTL,the association with other molecular phenotypes in light of genetic regulation,the regulators underlying m^(6)A genetics,and importantly,the functional roles of m^(6)A in mediating human complex ***,we discuss potential research avenues that can accelerate the translation of m^(6)A genetics studies toward the development of therapies for human genetic diseases.

关键词： m^(6)A disease genetics m^(6)A-QTL GWAS