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EXPLORATION OF TCM MASTERS KNOWLEDGE MINING

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Journal of Systems Science & Complexity 2008年第1期21卷 34-45页

作者： Xijin TANG nan ZHANG zheng WANG Institute of Systems Science Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100080 China.

Traditional Chinese medicine （TCM） has a rich knowledge about human health and disease by its special way evolved along a very long history. As modern medicine is achieving much progress, arguments and disputes toward TCM never end. To avoid losing precious knowledge of living TCM masters, endeavors have been engaged to systematic collection of those knowledge of TCM masters, such as their growth experiences, effective practical cases toward diseases and typical therapeutic principles and methods. Knowledge mining methods have been expected to explore some useful or hidden patterns to unveil some mysteries of the TCM system. In the paper, some computerized methods are applied toward those collected materials about some living TCM masters in China mainland to show a different way of exposing essential ideas of those TCM masters by correspondence visualization which aims to help people understand TCM holistic views toward disease and body, and facilitate tacit knowledge transfer and sense-making of the essence of TCM. The work is one kind of qualitative meta-synthesis of TCM masters＇ knowledge.

关键词： Idea map knowledge mining qualitative meta-synthesis traditional Chinese medicine.

Metal-free multicomponent polymerization toward cationic polyamidines

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Chinese Chemical Letters 2022年第5期33卷 2643-2647页

作者： Meng Du Ming Li Wangze Song nan zheng State Key Laboratory of Fine Chemicals School of Chemical EngineeringDalian University of TechnologyDalian 116024China

Cationic polymers,also known as polycations,are considered to be the most potential non-viral gene carriers due to their unique advantages such as the ability to bind the negative charge of nucleic acid *** polymerization(MCP)is a one-step,tandem strategy to construct complex structures based on multicomponent ***,we developed a metal-free MCP method based on three monomers of p-dinitrovinylbenzene(p-DNVB),1,1-dimethylethyl N,N-dibromocarbamate(BocNBr_(2)),and bis-secondary-amines with a ratio of 1:2:1,to access a library of Boc-substituted polyamidines with well-defined structures and suitable molecular weights(M w ranging from 4400Da to 11,000Da)in high yields(up to 85%)under mild *** the removal of Boc groups,a series of water-soluble polymers with cationic property were prepared and their gene binding capability was further evaluated.

关键词： XMulticomponent polymerization Metal-free Cationic polymer Polyamidine Water-soluble

Quantum software framework： a tentative study

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Frontiers of Computer Science 2013年第3期7卷 341-349页

作者： nan WU Haixing HU Fangmin SONG Huimin zheng Xiangdong LI State Key Laboratory for Novel Software Technology Nanjing University Nanjing 210093 China Department of Computer Science and Technology Nanjing University Nanjing 210093 China Department of Computer Science The Graduate School The City University of New York New York 10016 USA

In this paper we conduct a tentative study on the requirements and the structure for a quantum computer at the software level. From the software point of view, we describe the methodology used to minimize the decoherence. We con- struct the quantum instruction set for the higher-level computation. We also study the criteria for designing the quantum programming languages.

关键词： quantum software quantum computation quantum programming language

Vibration characteristics of multi-parametric excitations and multi-frequency external excitations of rolling mill under entry thickness fuctuation of strip

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Journal of Iron and Steel Research International 2020年第5期27卷 517-527页

作者： Teng Xu Dong-xiao Hou zheng-nan Sun Da-wu Guo School of Control Engineering Northeastern University at QinhuangdaoQinhuangdao 066004HebeiChina

A dynamic rolling force model with multi-parametric excitations and multi-frequency external excitations caused by entry thickness fuctuation of strip was *** on the dynamic rolling force,a nonlinear vertical vibration model with multi-parametric excitations and multi-frequency external excitations was *** method of multiple scales was used to solve the amplitude-frequency characteristic equation of primary resonance of the nonlinear vibration system of a rolling *** transition set and the topology structure of systematic global bifurcation were obtained by using the singularity ***,primary resonance characteristics of the system under entry thickness fuctuation of strip were analyzed by using actual parameters of the rolling *** global bifurcation curves with the change of amplitude and frequency of entry thickness fuctuation of strip were obtained by using numerical simulation,and many dynamic behaviors were found such as single-cycle motion,multi-cycle motion and chaotic motion,which can provide a theoretical reference for further restraining the vibration of a rolling mill.

关键词： Entry thickness fluctuation Dynamic rolling force Nonlinear vertical vibration Primary resonance Bifurcation

Scaffold-based tissue engineering strategies for soft-hard interface regeneration

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Regenerative Biomaterials 2023年第1期10卷 107-125页

作者： Yibo Li Mo Zhou Wenzhuo zheng Jianying Yang nan Jiang State Key Laboratory of Oral Diseases National Clinical Research Center for Oral DiseaseWest China Hospital of StomatologySichuan UniversityChengduChina Department of Outpatient nursing West China Second University Hospital&Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University)Ministry of EducationSichuan UniversityChengduChina

Repairing injured tendon or ligament attachments to bones(enthesis)remains costly and *** superb surgical management,the disorganized enthesis newly formed after surgery accounts for high recurrence rates after *** engineering offers efficient alternatives to promote healing and regeneration of the specialized enthesis ***-transmitting functions thus can be restored with appropriate biomaterials and engineering ***,recent studies have focused more on microstructure especially the arrangement of fibers since Rossetti successfully demonstrated the variability of fiber underspecific external *** this review,we provide an important update on the current strategies for scaffold-based tissue engineering of enthesis when natural structure and properties are equally *** firstly described compositions,structures and features of natural enthesis with their special mechanical properties *** for growth,development and healing of enthesis widely used in popular strategies are systematically *** discuss the fabrication of engineering scaffolds from the aspects of biomaterials,techniques and design strategies and comprehensively evaluate the advantages and disadvantages of each *** last,this review pinpoints the remaining challenges and research directions to make breakthroughs in further studies.

关键词： enthesis tissue engineering interface mechanical properties biomaterials

A multiaxial elastic potential with error-minimizing approximation to rubberlike elasticity

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Acta Mechanica Sinica 2015年第5期31卷 637-646页

作者： Zhi-Xiang Gu Lu Yuan zheng-nan Yin Heng Xiao State Key Laboratory of Advanced Special Steels Shanghai University Shanghai Institute of Applied Mathematics and Mechanics Shanghai University

This study is concerned with a new,explicit approach by means of which forms of the large strain elastic potential for multiaxial rubberlike elasticity may be obtained based on data for a single deformation *** a departure from usual studies,here for the first time errors may be estimated and rendered minimal for all possible deformation modes and,furthermore,failure behavior may be *** examples presented are in accurate agreement with Treloar＇s well-known data.

关键词： Rubberlike elasticity Large deformations Elastic potential Explicit approach Minimized errors

Gene delivery into isolated Arabidopsis thaliana protoplasts and intact leaves using cationic, a-helical polypeptide

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Frontiers of Chemical Science and Engineering 2017年第4期11卷 521-528页

作者： zheng, nan Song, Ziyuan Liu, Yang Cheng, Jianjun Yin, Lichen Univ Illinois Dept Mat Sci & Engn Urbana IL 61801 USA Dalian Univ Technol Sch Chem Engn Dept Polymer Sci & Engn State Key Lab Fine Chem Dalian 116024 Peoples R China Soochow Univ Inst Funct Nano & Soft Mat FUNSOM Jiangsu Key Lab Carbon Based Funct Mat & Devices Collaborat Innovat Ctr Suzhou Nano Sci & Technol Suzhou 215123 Peoples R China

The application of gene delivery materials has been mainly focused on mammalian cells while rarely extended to plant engineering. Cationic polymers and lipids have been widely utilized to efficiently deliver DNA and siRNA into mammalian cells. However, their applica- tion in plant cells is limited due to the different membrane structures and the presence of plant cell walls. In this study, we developed the cationic, a-helical polypeptide that can effectively deliver DNA into both isolated Arabidopsis thaliana protoplasts and intact leaves. The PPABLG was able to condense DNA to form nanocomplexes, and they exhibited significantly improved transfection efficiencies compared with commercial transfection reagent Lipofec- tamine 2000 and classical cell penetrating peptides such as poly（L-lysine）, HIV-TAT, arginine9, and poly（L-arginine）. This study therefore widens the utilities of helical polypeptide as a unique category of gene delivery materials, and may find their promising applications toward plant gene delivery.

关键词： a-helical polypeptide plant gene delivery,protoplast intact leaves transfection

Tunable liquid crystal grating based holographic 3D display system with wide viewing angle and large size

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Light(Science & Applications) 2022年第7期11卷 1575-1584页

作者： Yi-Long Li nan-nan Li Di Wang Fan Chu Sin-Doo Lee Yi-Wei zheng Qiong-Hua Wang School of Instrumentation and Optoelectronic Engineering Beihang UniversityBeijingChina Display Technology Research Center Seoul National UniversityGwanak-guSeoulRepublic of Korea

As one of the most ideal display approaches,holographic 3-dimensional(3D)display has always been a research hotspot since the holographic images reproduced in such system are very similar to what humans see the actual ***,current holographic 3D displays suffer from critical bottlenecks of narrow viewing angle and small ***,we propose a tunable liquid crystal grating-based holographic 3D display system with wide viewing angle and large *** tunable liquid crystal grating,providing an adjustable period and the secondary diffraction of the reconstructed image,enables to simultaneously implement two different hologram generation methods in achieving wide viewing angle and enlarged size,*** using the secondary diffraction mechanism of the tunable liquid crystal grating,the proposed system breaks through the limitations of narrow viewing angle and small size of holographic 3D *** proposed system shows a viewing angle of 57.4°,which is nearly 7 times of the conventional case with a single spatial light modulator,and the size of the reconstructed image is enlarged by about *** proposed system will have wide applications in medical diagnosis,advertising,education and entertainment and other fields.

关键词： holographic system angle

Luminescence: a new perspective for investigating perovskite precursors

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Science China Materials 2025年第01期 312-313页

作者： Haofeng zheng Shaocong Hou School of Electrical Engineering and Automation Wuhan University Wuhan University Shenzhen Research Institute

In the past two decades, perovskite materials have made significant progress in optoelectronic semiconductors, emerging as formidable candidates for the next generation of commercial solar cells, light-emitting diodes (LEDs), and *** the fundamental solution chemistry and photophysics in solution-processed perovskite devices is crucial for comprehending to achieve highly efficient optoelectronic devices.

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