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Multiple cone pathways are involved in photic regulation of retinal dopaminergic amacrine cells

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Multiple cone pathways are involved in photic regulation of ...

煤与瓦斯突出强度的IGA-LSSVM预测模型

中国神经科学学会第十二届全国学术会议

作者： Sheng-nan qiao Xiong-Li YANG Dao-Qi ZHANG Yong-Mei ZHONG Institutes of Brain Science State Key Laboratory of Medical Neurobiology and Collaborative Innovation Center for Brain Science Fudan University Eye Research Institute Oakland University

Objective Dopaminergic amacrine cells（DACs） are stimulated by photoreceptors to release dopamine, which plays a critical role in retinal light adaptation. Previous studies reported that DACs are activated by rods, cones, and the intrinsically photosensitive retinal ganglion cells（ip RGCs） upon illumination. However, it is still not clear how each class of photosensitive cells generates light responses in DACs. Here we genetically dissected out the cone function in mice to specifically examine the conemediated responses of DACs and their neural pathways. Methods We utilized a transgenic mouse model lacking rod and melanopsin function in which retinal DACs were labeled with red fluorescence protein. Light responses of DACs were recorded using whole-cell voltage clamp technique. Results Cones generate three classes of light responses in DACs: an initial ON response, a delayed ON（d-ON） response and an OFF response. The initial ON response is an excitatory postsynaptic current mediated by ON bipolar cells directly or indirectly via melanopsin-expressing ip RGCs. The d-ON response is an inhibitory postsynaptic current likely mediated by glycinergic amacrine cells exclusively driven by AMPA receptor-expressing OFF bipolar cells（presumably type 1）. The OFF response is also an inhibitory postsynaptic current but mediated by GABAergic/glycinergic amacrine cells and these amacrine cells are likely driven by kainate receptor-expressing OFF bipolar cells（presumably type 2/3 a）. Dye injections indicated that DACs had similar morphological profiles with or without ON/OFF inhibition. Conclusions Cones utilize specific and complex parallel excitatory and inhibitory circuits to modulate DAC activity and efficiently regulate dopamine release and the light-adaptive state of the retina.

关键词： amacrine cell dopamine retinal circuitry networks

来源： cnki会议评论

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辽宁工程技术大学学报（自然科学版） 2015年第7期34卷 791-796页

作者：王志宏乔楠辽宁工程技术大学工商管理学院辽宁葫芦岛125105

针对煤矿开采中煤与瓦斯突出强度的预测问题,利用免疫遗传算法和最小二乘支持向量机相结合的方法,选取最大主应力、瓦斯压力、瓦斯含量、顶板岩性、距断裂距离、煤层厚度、开采垂直深度、绝对瓦斯涌出量、相对瓦斯涌出量等9个主要影响因... 详细信息

针对煤矿开采中煤与瓦斯突出强度的预测问题,利用免疫遗传算法和最小二乘支持向量机相结合的方法,选取最大主应力、瓦斯压力、瓦斯含量、顶板岩性、距断裂距离、煤层厚度、开采垂直深度、绝对瓦斯涌出量、相对瓦斯涌出量等9个主要影响因素.对相关程度较高的因素进行因子分析,提取公共因子作为IGA-LSSVM模型的输入,建立基于因子分析和IGA-LSSVM的煤与瓦斯突出强度的预测模型.利用实测的14组数据作为学习样本,训练预测模型.另外5组数据作为测试样本,使用所得模型进行预测.研究结果表明:经过免疫遗传算法优化最小二乘支持向量机的参数后,所得模型可有效预测煤与瓦斯突出的强度,检验结果的误判率为0.

关键词：煤矿灾害突出强度因子分析免疫遗传算法最小二乘支持向量机

Multi-dimensional Bi@C electrocatalyst for Cr3+/Cr2+ redox reaction boosting high-performance iron-chromium flow batteries

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Science China Chemistry 2025年

作者： Min Wu Mingjun nan Shumin Liu Caihe Zhong Lin qiao Huamin Zhang Xiangkun Ma Department of Materials Science and Engineering Dalian Maritime University Division of Energy Storage Dalian National Laboratory for Clean Energy Dalian Institute of Chemical Physics Chinese Academy of Sciences

With the increasing demand for energy storage technology, iron-chromium flow batteries（ICFBs） have been widely concerned because of their price advantage. However, the low electrochemical activity of Cr3+/Cr2+redox couples and the side hydrogen evolution reaction limit the industrial application of ICFBs. A multi-dimensional Bi/carbon composite electrocatalyst（Bi@C）for ICFB is designed and prepared to improve the electrochemical activity of Cr3+/Cr2+redox couples. Benefiting by using the Bimetal organic framework（Bi-MOF） with solid matrix as precursors, Bi nanospheres are highly dispersed on the Bi@C electrocatalyst that effectively enhances the electrochemical activity. The special morphology of Bi@C electrocatalyst helps the transfer of electrons and ions, significantly reducing the polarization of battery. Herein, the 3D porous carbon frames accelerate mass transfer, and the 2D carbon nanobelts and carbon layer coating on 0D Bi nanospheres improve the conductivity of Bi nanospheres. Therefore, the ICFB with multi-dimensional Bi@C electrocatalyst exhibits coulombic efficiency of 98.10% and energy efficiency of 79.14% at 140 mA cm-2, which is higher than ICFBs with commercial graphite carbon electrocatalyst and with heat treatment carbon felt. This work provides a simple and economical method to fabricate a high-performance multidimensional Bi@C electrocatalyst for Cr3+/Cr2+redox couples, boosting the development of ICFBs.

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关于对称性的一个定理及其应用

数学的实践与认识 2007年第21期37卷 203-208页

作者：袁南桥四川文理学院数学系四川达州635000

在一个问题中存在某种对称性时,若能充分利用这一性质,常常可以起到化繁为简,变难为易的作用.本文给出一个关于对称性的定理,以及它在定积分中的一些应用.某些经典的定积分定理和一些已知的结论,均可作为其推论.

关键词：对称性定积分定理应用

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光敏可调的多波段电磁诱导透明超材料分析

中国激光 2019年第1期46卷 353-362页

作者：李广森延凤平王伟乔楠北京交通大学光波技术研究所全光网络与现代通信网教育部重点实验室北京100044

设计了一种基于光敏半导体砷化镓的主动式电磁诱导透明超材料。砷化镓的光电特性使该超材料结构中的外围圆环能在各个光照条件下响应不同频率的电磁波;其与中心开口环耦合,分别能够在1.47THz与0.7THz两个频点处产生强烈的电磁诱导透明... 详细信息

设计了一种基于光敏半导体砷化镓的主动式电磁诱导透明超材料。砷化镓的光电特性使该超材料结构中的外围圆环能在各个光照条件下响应不同频率的电磁波;其与中心开口环耦合,分别能够在1.47THz与0.7THz两个频点处产生强烈的电磁诱导透明效应。通过调节光照强度来改变砷化镓的电导率,并拆分表面金属环结构进行对比,分析了该超材料结构的光敏性能与其实现多波段电磁诱导透明效应的物理机理;同时研究了砷化镓宽度、中心开口环开口大小与基底厚度对电磁诱导透明效应的影响。仿真结果表明,该超材料结构能够在不同光照条件下,于太赫兹波段的多个频点处产生高强度的波速迟滞效应,并伴随较高的折射率灵敏度,在太赫兹缓存器件与折射率传感领域有一定的应用价值。

关键词：材料电磁诱导透明多波段可调谐太赫兹迟滞效应折射率传感

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混凝土结构碳化寿命的时变可靠度分析

哈尔滨工业大学学报 2007年第6期39卷 967-971页

作者：田冠飞安雪晖沈乔楠清华大学水沙科学与水利水电工程国家重点实验室

在一般大气环境下,混凝土结构的耐久性问题主要是由于碳化引起的钢筋锈蚀问题.碳化造成混凝土结构从新建到最终失效破坏过程包括:混凝土中钢筋开始发生锈蚀;混凝土保护层开始出现顺筋裂缝;裂缝宽度达到不容许值或混凝土保护层锈胀剥落... 详细信息

在一般大气环境下,混凝土结构的耐久性问题主要是由于碳化引起的钢筋锈蚀问题.碳化造成混凝土结构从新建到最终失效破坏过程包括:混凝土中钢筋开始发生锈蚀;混凝土保护层开始出现顺筋裂缝;裂缝宽度达到不容许值或混凝土保护层锈胀剥落等三个阶段.采用拟Monte-Carlo随机模拟方法,计算了以上述三个状态作为极限我状态所对应的时变失效概率,计算结果令人满意.该方法可以应用于混凝土结构受钢筋腐蚀破坏的耐久性寿命预测中.

关键词： RC结构混凝土碳化钢筋锈蚀极限状态方程拟Monte-Carlo法