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Performance test of a Neutron Detector Using side-Lighting Optical Fiber

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Performance Test of a Neutron Detector Using Side-Lighting O...

mi R-122 negatively correlates with liver fibrosis as detected by histology and Fibroscan

作者： H.tanaka Y.sakurai J.Hori t.Misawa t.Yagi Y.Kawabata M.suzuki s,Masunaga A.Maruhashi K.Ono Research Reactor Institute Kyoto University

INtRODUCtION:to detect two-dimensional distribution of thermal neutrons is necessary for treatment of Boron Neutron Capture therapy(BNCt).In general, two-dimensional array wavelength shifter fiber coupled with scintillator has been used as neutron imaging detector. However,at the neutron field of BNCt,thermal neutron flux is very high up to 10(n/cm/s) compared with other neutron fields such as neutron scattering experiments etc..the deterioration of the signal caused by radiation damage in wavelength shifting fiber will be serious problem to obtain precise information of thermal

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World Journal of Gastroenterology 2015年第25期21卷 7814-7823页

作者： tünde Halász Gábor Horváth Gabriella Pár Klára Werling András Kiss Zsuzsa schaff Gábor Lendvai second Department of Pathology Semmelweis University Department of Pathology Military Hospital Hepatology Center of Buda 1111 BudapestHungary First Department of Medicine University of Pécs second Department of Internal Medicine Semmelweis University MtA-sE tumor Progression Research Group Semmelweis University

AIM: to investigate whether expression of selected mi RNAs obtained from fibrotic liver biopsies correlate with fibrosis ***: Altogether, 52 patients were enrolled in the study representing various etiologic backgrounds of fibrosis: 24 cases with chronic hepatitis infections.t.pes B, C), 19 with autoimmune liver diseases(autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, overlapping syndrome cases), and 9 of mixed etiology(alcoholic and nonalcoholic steatosis, cryptogenic cases). severity of fibrosis was determined by both histologic staging using the MEtAVIR scoring system and noninvasive transient elastography. Following RNAisolation, expression levels of mi R-21, mi R-122, mi R-214, mi R-221, mi R-222, and mi R-224 were determined using taq Man Micro RNA Assays applying mi R-140 as.t.e reference. selection of mi RNAs was based on their characteristic up- or downregulation observed in hepatocellular carcinoma. Relative expression of mi RNAs was correlated with fibrosis stage and liver stiffness(Ls) value measured by transient elastography, as well as with serum alanine aminotransferase(ALt) ***: the expression of individual mi RNAs showed deregulated patterns in stages F1-F4 as compared with stage F0, but only the reduced level of mi R-122 in stage F4 was statistically significant(P ssion in relation to fibrosis, levels of mi R-122 and mi R-221 showed negative correlations with fibrosis stage, and mi R-122 was found to correlate negatively and mi R-224 pos.t.vely with Ls values(all P t levels displayed a pos.t.ve correlation with mi R-21(P tive correlations were observed in the fibrosis samples of mixed etiology between mi R-122 and fibrosis stage and Ls values(P the samples of chronic viral hepatitis, between mi R-221 and fibrosis stage(P s mi R-21 showed pos.t.ve correlation with ALt values in the samples of autoimmune live

关键词： Expression Fibroscan Liver fibrosis MEtAVIR microRNA miR-122

Application of Reactive Ion Etching to the Fabrication of Microstructure on Mo/si Multilayer

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Chinese Physics Letters 1999年第9期16卷 665-666页

作者： LE Zi-chun L.Dreeskornfeld s.Rahn R.segler U.Kleineberg U.Heinzmann Institute of Atomic and Molecular Physics Jilin UniversityChangchun 130012 Fakultät für Physik Universität BielefeldUniversitatsstraβe 25D-33615 BielefeldGermany

Mo/si muitilayer mirrors(30 periods,doublelayer thickness 7nm)with the AZ-PF514 resist pattern whose smallest lines and spaces structure was 0.5pm were etched by reactive ion etching(RIE)in a fluorinated *** etch rate,selectivity and etch profile were investigated as a function of the gas mixture,pressure,and plasma rf *** groove depth and the etch proHle were investigated by an atomic force microscope before RIE,after RIE and after resist removal.

关键词： Mo/si smallest selectivity

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应用人工神经网络预测转杯纱性能

国际纺织导报 2004年第3期32卷 30-34页

作者： D.Das s.M.Is.t.aque t.Mac t.Gries 陈廷印度技术学院亚琛纺织技术学院

应用人工神经网络对不同混纺比转杯纱的性能进行预测。研究中使用的原料为棉、聚酯纤维、粘胶纤维和亚麻。这些纤维以不同混坊比进行随机混合,在Uster MDtA 3设备上加工成条子。然后,在一台转杯纺小样机上将这些条子纺制成388个转杯纱... 详细信息

应用人工神经网络对不同混纺比转杯纱的性能进行预测。研究中使用的原料为棉、聚酯纤维、粘胶纤维和亚麻。这些纤维以不同混坊比进行随机混合,在Uster MDtA 3设备上加工成条子。然后,在一台转杯纺小样机上将这些条子纺制成388个转杯纱纱样。测试了纱线的拉伸性能、条干不匀率、毛羽和捻度。研究中采用基于误差反向传播算法的人工神经网络软件ItANEt-3.7预测纱线性能。通过对不同网络参数进行优化得到了最佳的网络结构,还研究了该网络的性能。

关键词：转杯纱混纺比转杯纺纱线性能小样捻度毛羽条干不匀率聚酯纤维混合

Illustrative Key to the Particle Listings

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Chinese Physics C 2014年第9期38卷 547-556页

作者： K.A.Olive K.Agashe C.Amsler M.Antonelli J.-F.Arguin D.M.Asner H.Baer H.R.Band R.M.Barnett t.Basaglia C.W.Bauer J.J.Beatty V.I.Belousov J.Beringer G.Bernardi s.Bethke H.Bichsel O.Biebe E.Blucher s.Blusk G.Brooijmans O.Buchmueller V.Burkert M.A.Bychkov R.N.Cahn M.Carena A.Ceccucci A.Cerr D.Chakraborty M.-C.Chen R.s.Chivukula K.Copic G.Cowan O.Dahl G.D'Ambrosio t.Damour D.de Florian A.de Gouvea t.DeGrand P.de Jong G.Dissertor B.A.Dobrescu M.Doser M.Drees H.K.Dreiner D.A.Edwards s.Eidelman J.Erler V.V.Ezhela W.Fetscher B.D.Fields B.Foster A.Freitas.t.K.Gaisser H.Gallagher L.Garren H.-J.Gerber G.Gerbier t.Gershon t.Gherghetta s.Golwala M.Goodman C.Grab A.V.Gritsan C.Grojean D.E.Groom M.Grnewald A.Gurtu t.Gutsche H.E.Haber K.Hagiwara C.Hanhart s.Hashimoto Y.Hayato K.G.Hayes M.Heffner B.Heltsley J.J.Hernandez-Rey K.Hikasa A.Hocker J.Holder A.Holtkamp J.Huston J.D.Jackson K.F.Johnson t.Junk M.Kado D.Karlen U.F.Katz s.R.Klein E.Klempt R.V.Kowalewski F.Krauss M.Kreps B.Krusche Yu.V.Kuyanov Y.Kwon O.Lahav J.Laiho P.Langacker A.Liddle Z.Ligeti C.-J.Lin t.M.Liss L.Littenberg K.s.Lugovsky s.B.Lugovsky F.Maltoni t.Mannel A.V.Manohar W.J.Marciano A.D.Martin A.Masoni J.Matthews D.Milstead P.Molaro K.Monig F.Moortgat M.J.Mortonson H.Murayama K.Nakamura M.Narain P.Nason s.Navas M.Neubert P.Nevski Y.Nir L.Pape J.Parsons C.Patrignani J.A.Peacock M.Pennington s.t.Petcov Kavli IPMU A.Piepke A.Pomarol A.Quadt s.Raby J.Rademacker G.Raffel B.N.Ratcliff P.Richardson A.Ringwald s.Roesler s.Rolli A.Romaniouk L.J.Rosenberg J L.Rosner G.Rybka C.t.sachrajda Y.sakai G.P.salam s.sarkar F.sauli O.schneider K.scholberg D.scott V.sharma s.R.sharpe M.silari t.sjostrand P.skands J.G.smith G.F.smoot s.spanier H.spieler C.spiering A.stahl t.stanev s.L.stone t.sumiyoshi M.J.syphers F.takahashi M.tanabashi J.terning L.tiator M.titov N.P.tkachenko N.A.tornqvist D.tovey G.Valencia G.Venanzoni M.G.Vincter P.Vogel A.Vogt s.P.Wakely W.Walkowiak C.W.Walter D.R.Ward G.Weiglein D.H.Weinberg E.J.Weinberg M.White L.R.Wiencke C.G.Wohl L.Wolfenstein J.Womersley C.L. Univers.t. of Minnes.t. School of Physics and Astronomy116 Church St.S.E.MinneapolisMN 55455USA Univers.t. of Maryland Department of PhysicsCollege ParkMD 20742-4111USA Albert Einstein Center for Fundamental Physics Universitat BernCH-3012 BernSwitzerland Lab.Nazionali di Frascati dell'INFN CP 13via E.Fermi40I-00044 Frascati(Roma)Italy Departement de physique Universite de MontrealC.P.6128succ.centre-villeMontreal(Quebec) H3C 3J7Canada Pacific Northwest National Laboratory 902 Battelle BoulevardRichlandWA 99352USA Department of Physics and Astronomy University of OklahomaNormanOK 73019USA Department of Physics University of WisconsinMadisonWI 53706USA Physics Division Lawrence Berkeley National Laboratory1 Cyclotron RoadBerkeleyCA 94720USA CERN European Organization for Nuclear ResearchCH-1211 Geneve 23Switzerland Department of Physics The Ohio State University191 W.Woodruff Ave.ColumbusOH 43210 COMPAs Group Institute for High Energy PhysicsRU- 142284ProtvinoRussia LPNHE IN2P3-CNRS et Universites de Paris 6 et 7F-75252 ParisFrance Max-Planck-Institute of Physics 80805 MunichGermany Department of Physics University of WashingtonSeattleWA 98195USA Ludwig-Maximilians-Univers.t.t Fakultdt für PhysikSchellingstr.4D-80799 MünchenGermany Enrico Fermi Institute and Department of Physics University of ChicagoChicagoIL 60637-1433USA Department of Physics Syracuse UniversitySyracuseNY13244USA Department of Physics Columbia University538 W.120th StreetNew YorkNY10027 USA High Energy Physics Group Blackett LaboratoryImperial CollegePrince Consort RoadLondon SW7 2AZUK Jefferson Lab 12000 Jefferson Ave.Newport NewsVA 23606USA Department of Physics University of VirginiaPO Box 400714CharlottesvilleVA 22904USA Fermi National Accelerator Laboratory P.O.Box 500BataviaIL 60510USA Kavli Institute for Cosmological Physics University of ChicagoChicagoIL 60637-1433USA Department of Physics and Astronomy University of SussexFalmerBrighton BN1 9QHUK Department o

Name of particle. ＂Old＂ name used before 1986 renaming scheme also given if different. see the section ＂Naming scheme for Hadrons＂ for details.

关键词： HBC Illustrative Key to the Particle Listings

tuning the Morphology of Pharmaceutical Compounds via Model Based solvent selection

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Chinese Journal of Chemical Engineering 2008年第3期16卷 465-473页

作者： ArunPrakash t. Karunanithi Charles Acquah LukeE. K. Achenie National Risk Management Research Laboratory U.S. Environmental Protection Agency Cincinnati Ohio USA Department of Chemical Materials ＆ Biomolecular Engineering University of Connecticut Storrs Connecticut USA Department of Chemical Engineering Virginia Polytectmic Institute and State University Blacksburg Virginia USA

In this paper we present a strategy for tuning the crystal morphology of pharmaceutical compounds by the appropriate choice of solvent via an optimization model. A three-stage approach involving a pre-design stage, a product design stage and a post-design experimental verification stage is presented. the pre-design stage addresses.t.e tormulation of the property constraint tor crystal morphology. this involves crystallization experiments aria development of property models and constraints for morphology. In the design stage various property requirements for the solvent along with crystal morphology are considered and the product design problem is formulated as a mixed integer nonlinear programming *** design stage provides an optimal solvent/list of candidate solvents. similar to the pre-design stage, in the post design experimental verification stage, the morphology of the crystals （precipitated from the designed solvent） is verified through crystallization experiments followed by product characterization via scanni＇ng electron microscopy, powder X-ray diffraction imaging and Fourier transform spectra analysis.

关键词： morphology solvent selection nonlinear programming crystallization product design

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高性能发动机活塞销衬套材料的研制

汽车与新动力 2000年第4期 22-26页

作者： Kira t Yokota H Kamiya s 顾如龙

近年来,柴油机要求更高的性能和更长的寿命。由于气缸爆发压力高,活塞销衬套的工作负荷和温度变得更高。因此要求活塞销衬套具有高承载能力、耐磨性和耐腐蚀性。为了改善铜衬套材料的耐腐蚀性,研究了铜合金中添加元素的效果。研究发现,... 详细信息

近年来,柴油机要求更高的性能和更长的寿命。由于气缸爆发压力高,活塞销衬套的工作负荷和温度变得更高。因此要求活塞销衬套具有高承载能力、耐磨性和耐腐蚀性。为了改善铜衬套材料的耐腐蚀性,研究了铜合金中添加元素的效果。研究发现,在铜中加入镍可降低铜合金的硫腐蚀。此外,还得知可以通过传统的烧结方法来生产铜镍合金。尝试在铜基体中加入硬颗粒来提高耐磨性。研究的首要目标是确定硬颗粒对耐磨性和切削加工工艺性的影响。研究发现,在铜基体中加入一种硬颗粒时耐磨性有所提高,但切削加工性却变差。为了解决这个问题,试验同时添加两种硬颗粒,细的AIN和Fe3P颗粒。结果是成功地提高了耐磨性,又不使切削加工性变差。在本研究的基础上成功地开发了活塞销衬套新材料,有效地提高了高性能柴油机活塞销衬套的耐磨性和耐腐蚀性。

关键词：柴油机活塞销轴承材料

Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo

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the Journal of Biomedical Research 2016年第4期30卷 272-284页

作者： Matthew G.K. Benesch Xiaoyun tang Ganesh Venkatraman Raie t. Bekele David N. Brindley signal transduction Research Group Department of Biochemistry University of Alberta T6G 2S2 Canada.

Extracellular lysophosphatidate （LPA） is a potent bioactive lipid that signals.t.rough six G-protein-coupled receptors. this signaling is required for embryogenesis, tissue repair and remodeling processes. LPA is produced from circulating lysophosphatidylcholine by autotaxin （AtX）, and is degraded outside cells by a family of three enzymes called the lipid phosphate phosphatases （LPPs）. In many pathological conditions, particularly in cancers, LPA concentrations are increased due to high AtX expression and low LPP activity. In cancers, LPA signaling drives.t.mor growth, angiogenesis, metastasis, resistance to chemotherapy and decreased efficacy of radiotherapy. Hence, targeting the AtX-LPA-LPP axis is an attractive strategy for introducing novel adjuvant therapeutic options. In this review, we will summarize current progress in targeting the AtX-LPA-LPP axis with inhibitors of autotaxin activity, LPA receptor antagonists, LPA monoclonal antibodies, and increasing low LPP expression. some of these agents are already in clinical trials and have applications beyond cancer, including chronic inflammatory diseases.

关键词： cancer chronic inflammation cytokines monoclonal antibodies wound repair

Critical Approach to Methods of Glacier Reconstruction in High Asia and Discussion of the Probability of a Qinghai-Xizang (tibetan) Inland Ice

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Journal of Mountain science 2007年第2期4卷 91-123页

作者： Matthias Kuhle Geographie/Hochgebirgsgeomorphologie Geographisches Institut der Universitt Goldschmidtstr.5 37077 Gttingen Germany

this overview discusses old and new results as.t. the controversy on the past glacier extension in High Asia, which has been debated for 35 years now. this paper makes an attempt to come closer to a solution. H.v. Wissmann's interpretation (1959) of a small-scale glaciation contrasts with M. Kuhle's reconstruction (1974) of a large-scale glaciation with a 2.4 million km2 extended Qinghai-Xizang (tibetan) inland glaciation and a Himalaya-Karakorum icestream network. Both opinions find support but also contradiction in the International and Chinese literature (Academia sinica). the solution of this question is of supraregional importance because of the subtropical pos.t.on of the concerned areas. In case of large albedo-intensive ice surfaces, a global cooling would be the energetical consequence and, furthermore, a breakdown of the summer monsoon. the current and interglacial heat-low above the very effective heating panel of the Qinghai-Xizang (tibetan) Plateau exceeding 4000 m, which gives rise to this monsoon circulation, would be replaced by the cold-high of an inland ice. In addition, the plate-tectonically created Pleistocene history of the uplift of High Asia — should the occasion arise up to beyond the snowline (ELA) —would attain a paleoclimatically great, perhaps global importance. In case of a heavy superimposed ice load, the question would come up as.t. the glacio-isostatic interruption of this primary uplift. the production of the loesses sedimentated in NE-China and their very probable glacial genesis as well as an eustatic lowering of the sea-level by 5 to 7 m in the maximum case of glaciation are immediately tied up with the question of glaciation we want to discuss. Not the least, the problems of biotopes of the sanctuary-centres of flora and fauna, i.e., interglacial re-s.t.lement, are also dependent on it. On the basis of this Quaternary- geomorphological-glaciological connection, future contributions are requested on the past glaciation, the curre

关键词： Approach methods inland ice glacier reconstruction High Asia Qinghai-Xizang (tibetan)