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Larvicidal and irritant activities of hexane leaf extracts of Citrus sinensis against dengue vector Aedes aegypti L.

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Asian Pacific Journal of Tropical Biomedicine 2012年第2期2卷 152-155页

作者： Radhika Warikoo Ankita Ray Jasdeep Kaur Sandhu Roopa Sanial naim.Wahab Sarita Kumar Department of Zoology Acharya Narendra Dev CollegeUniversity of Delhi

Objective:To assess the larvicidal and irritant activities of the hexane extracts of leaves of Citrus sinensis(***)against the early fourth instars and female adults of Aedes aegypti(***).Methods:The larvicidal potential of the prepared leaf extract was evaluated against early fourth instar larvae of *** using WHO *** mortality counts were made after 24 h and LC_(50)and LG_(50)values were *** efficacy of extract as mosquito irritant was assessed by contact irritancy ***-impregnated paper was placed on a glass plate over which a perspex funnel with a hole on the top was kept *** female adult,3-day old unfed/blood-fed,was released inside the *** 3 min of acclimatization time,the time taken for the first take-off and total number of flights undertaken during 15 min were ***:The citrus leaf extracts from hexane possessed moderate larvicidal efficiency against dengue *** bioassays resulted in an LC_(50)and LC_(90)value of 446.84 and 1370.96 ppm,respectively after 24 h of ***,the extracts were proved to be remarkable irritant against adults ***,more pronounced effects being observed on blood-fed females than unfed *** extract-impregnated paper was thus proved to be 7-11 times more irritable as compared with the control ***:The hexane extracts from *** leaves are proved to be reasonably larvicidal But remarkably irritant against dengue *** studies are needed to identify the possible role of extract as adulticide,oviposition deterrent and ovicidal *** isolation of active ingredient from the extract could help in formulating strategies for mosquito control.

关键词： Citrus Hexane Larvicide Irritancy Take-offs Citrus sinensis Aedes aegypti Larvicidal activity Irritant activity Dengue vector Mosquito control

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High Vegetation of Lake Ayakagitma in Bukhara Region and Their Distribution

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American Journal of Plant Sciences 2022年第11期13卷 1373-1380页

作者： Shamsiyev naim.Amonovich Qobilov Aziz Muxtorovich Bukhara State University Bukhara Uzbekistan

More than 500 lakes are found in Uzbekistan. Ayakagitma Lake is located on the border of the Northern Gijduvon and Shafirkon districts of Bukhara region. This lake was formed in 1985-1986 at the expense of the waters of the sewage dump collector. The area of the lake is 8200 hectares, the maximum depth is 35 m, on average 10 - 15 m, the minimum is 3 - 5 meters. The chemical composition of lake water is chloride-sulfate and has a calcareous character. 67 species of high plants belonging to 22 families were found in this area. 17 of these species are found in the water of the lake and 50 species are found around it. Of the most common species, Phragmites communis reach a height of 4.5 - 5.5 meters. Phragmites communis make up the total area of the lake 8 - 10 hectares.

关键词： Mesotrophic Zooplankton Zoobentos Nectobentos Bentos Detritus Mesophytes Xerophytes Hygrophytes Biomass

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易测量非球面定义及应用（英文）

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中国光学 2017年第2期10卷 256-266页

作者： YOUSSEF Al-Khatib MOHAMED Fawaz Mousselly MAMOUN naim 叙利亚应用科学与技术高等学校大马士革31983

本文提出了一种新型、易于用传统光学干涉仪测量的非球面。该非球面的检测主要基于Zemax光学程序软件设计的多重配置特性。第一配置为易于测量非球面,第二配置为采用平行平面玻璃板或单透镜作为零位校正器,用于检测第一配置的非球面。... 详细信息

本文提出了一种新型、易于用传统光学干涉仪测量的非球面。该非球面的检测主要基于Zemax光学程序软件设计的多重配置特性。第一配置为易于测量非球面,第二配置为采用平行平面玻璃板或单透镜作为零位校正器,用于检测第一配置的非球面。本文通过一些实例,说明了易测量非球面检测技术的应用和优势,证实了与圆锥或普通非球面相比,易测量非球面更易于操作与检测,同时有利于减小光学像差。

关键词：易测量非球面干涉仪零位检验

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Ozone Therapy in a Patient with Diabetic Foot Ulcerations and a Decision for Amputation

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Case Reports in Clinical Medicine 2019年第2期8卷 35-41页

作者： Saltuk Aytacoglu Barlas naim.Aytacoglu Vocational School of Health Girne American University Girne TRNC Faculty of Medicine Girne American University Girne TRNC

Background: Diabetic foot together with open wounds in distal type peripheral arterial disease constitutes a challenge in therapeutic planning. Ozone therapy may unveil new horizons in management. Case Report: A 67-year-old woman with diabetes mellitus was applied with open wounds at the bottom of her foot with purulent discharge, with a decision for above ankle amputation. She had had numerous interventions for her wounds including metatarsal amputations due to osteomyelitis and had been on an intense treatment including antibiotics, insulin, antihypertensives and antiaggregants. Angiogram revealed diffuse peripheral arterial disease in lower extremities. All medication but antihypertensives was stopped. She received major medical ozone application as 2000 gamma/session i.v. for 2 weeks, external ozone sac application starting from 60 and dropping to 30 gamma/session for 3 weeks and ozone insuflation 40 gamma/session for 10 sessions. Her purulent discharge ceased after the third session and the atonic debris of the wounds exfoliated, the wounds healed from the base towards the surface of the skin. She was then put on cilostazol and clopidogrel therapy. Conclusion: By being one of the known strongest bactericide, virucide, and fungicide elements, medical ozone therapy stimulates and upregulates the antioxidant system of the body with its hormesis effects. After the cessation of all circulatory system supporting medication (as their interaction with ozone is not clear yet), appropriate ozone therapy may bring new horizons for patients when all classically known methods of treatment have been completed, before assigning the patients for amputation.

关键词： Diabetic Foot Ulceration Medical Ozone Treatment Diabetes Mellitus Extremity Amputation

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A comparison study between one-class and two-class machine learning for MicroRNA target detection

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Journal of Biomedical Science and Engineering 2010年第3期3卷 247-252页

作者： Malik Yousef naim.Najami Waleed Khalifav 不详

The application of one-class machine learning is gaining attention in the computational biology community. Different studies have described the use of two-class machine learning to predict microRNAs (miRNAs) gene target. Most of these methods require the generation of an artificial negative class. However, designation of the negative class can be problematic and if it is not properly done can affect the performance of the classifier dramatically and/or yield a biased estimate of performance. We present a study using one-class machine learning for miRNA target discovery and compare one-class to two-class approaches. Of all the one-class methods tested, we found that most of them gave similar accuracy that range from 0.81 to 0.89 while the two-class naive Bayes gave 0.99 accuracy. One and two class methods can both give useful classification accuracies. The advantage of one class methods is that they don’t require any additional effort for choosing the best way of generating the negative class. In these cases one- class methods can be superior to two-class methods when the features which are chosen as representative of that positive class are well defined.

关键词： MicroRNA One-Class Two-Class Machine Learning

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初来乍到

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疯狂英语（初中天地） 2008年第6期 4-5页

作者： Yael naim.童桦

歌的故事随着Macbook Air最新广告的推出,这首歌渐渐流传开来。苹果慧眼识珠地发掘了来自法国的以色列歌手Yael naim.—这个大器晚成的女孩自幼潜心钢琴,

关键词：大团圆结局

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Simple diagnostic algorithm identifying at-risk nonalcoholic fatty liver disease patients needing specialty referral within the United States

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World Journal of Hepatology 2022年第8期14卷 1598-1607页

作者： naim.Alkhouri Pankaj Aggarwal Phuc Le Julia Payne Celine Sakkal Prido Polanco Stephen Harrison Mazen Noureddin Department of Hepatology Arizona Liver HealthChandlerAZ 85712United States Center for Value-Based Care Research Cleveland ClinicClevelandOH 44195United States Department of Research Pinnacle ResearchSan AntonioTX 78229United States Department of Hepatology Cedars Sinai Medical CenterLos AngelesCA 90048United States

BACKGROUND There is an urgent need to risk stratify patients with suspected nonalcoholic fatty liver disease(NAFLD)and identify those with fibrotic nonalcoholic *** study aims to apply a simple diagnostic algorithm to identify subjects with at-risk NAFLD in the general *** To apply a simple diagnostic algorithm to identify subjects with at-risk NAFLD in the general *** Adult subjects were included from the National Health and Nutrition Examination Survey database(2017-2018)if they had elevated alanine aminotransferase(ALT)and excluded if they had evidence of viral hepatitis or significant alcohol consumption.A fibrosis-4(FIB4)cutoff of 1.3 differentiated patients with low risk vs high risk *** patients had FIB4>1.3,a FAST score0.35 were referred to a *** same algorithm was applied to subjects with type 2 diabetes mellitus(T2DM).RESULTS Three thousand six hundred and sixty-nine patients were identified who met all inclusion and exclusion *** this cohort,911(28.6%)patients had elevated ALT of which 236(22.9%)patients had elevated FIB4 scores≥*** patients with elevated FIB4 score,75(24.4%)had elevated FAST scores,ruling in advanced *** accounts for 2.0%of the overall study *** this algorithm to 737 patients with T2DM,213(35.4%)patients had elevated ALT,85(37.9%)had elevated FIB4,and 42(46.1%)had elevated FAST *** accounts for 5.7%of the population with *** The application of this algorithm to identify at-risk NAFLD patients in need for specialty care is feasible and demonstrates that the vast majority of patients do not need subspecialty referral for NAFLD.

关键词： Non-alcoholic fatty liver disease Nonalcoholic steatohepatitis Hepatology Diabetes Endocrinology Primary care

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Variation in Thermal time model Parameters Between Two Contrasting Chickpea (<i>Cicer arietinum</i>) cultivars

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Agricultural Sciences 2015年第12期6卷 1421-1427页

作者： Atif Hassan naim.Faisal El Gasim Ahmed Faculty of Agricultural and Environmental Sciences University of Gadarif Gadarif Sudan Faculty of Agriculture University of Khartoum Shambat Sudan

A laboratory experiment was carried out to determine the effect of different constant temperatures on germination and early seedling establishment and to study the variation among parameters of thermal time model parameters for two contrasting chickpea cultivars . Seeds were subjected to six constant temperatures from 10 o C to 35 o C . A complete randomized design was used with four replication. Analysis of variance showed significant differences among treatments for all characters studied. The final germination percentage significantly increased with increasing temperature up to 25 ° C, and thereafter there was a sharp decrease in final germination at 30 ° and 35 ° C. Desi type cultivar (small seeded) “Jabel Marra” significantly exhibited higher final germination percentage and lower germination rate compared with the kabui type cultivar “Shendi” at all temperatures. The median (θ T(50) ) of the thermal time was significantly differ between the two chickpea cultivars. The large seeded cultivars (shendi) recorded significantly higher median thermal time than the small seeded cultivars (Jabel Marra). The results also revealed a significant differences between the two cultivars in all thermal time model parameters. The small seeded cultivar (Jabel Marra) scored lower total dry matter and temperature tolerance index (TTI) compared to the large seeded cultivar (Shendi) at all temperatures studied.

关键词： Cicer arietinum Chickpea Base temperture Germination Thermal time model

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市售长叶松油和锡兰肉桂油对登革热媒蚊埃及伊蚊的灭幼效果(英文)

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昆虫学报 2011年第7期54卷 793-799页

作者： Radhika WARIKOO naim.WAHAB Sarita KUMAR Department of Zoology Acharya Narendra Dev CollegeUniversity of DelhiKalka Ji

松油和桂皮油由于具有芳香性气味,因而成为良好的成虫驱避剂,但是关于它们对蚊虫的杀幼虫作用研究不多。为揭示市售的长叶松Pinus longifolia油和锡兰肉桂Cinnamomum zeylanicum油对来源于印度德里的埃及伊蚊Aedes aegypti4龄幼虫的毒... 详细信息

松油和桂皮油由于具有芳香性气味,因而成为良好的成虫驱避剂,但是关于它们对蚊虫的杀幼虫作用研究不多。为揭示市售的长叶松Pinus longifolia油和锡兰肉桂Cinnamomum zeylanicum油对来源于印度德里的埃及伊蚊Aedes aegypti4龄幼虫的毒杀潜力,我们进行了室内研究,以幼虫死亡率及行为改变和形态改变等指标评估其杀幼虫潜力。结果表明:两种油对埃及伊蚊4龄幼虫均具有毒杀作用,且松油的灭幼效果优于桂皮油。松油的LC50和LC70值分别为0.33093mg/L和0.54476mg/L,而桂皮油的LC50和LC70值分别为0.63159mg/L和0.77736。进一步观察发现,LC90剂量下桂皮油的杀幼虫潜力强于松油,其LC90为1.11879mg/L,而松油的LC90为1.04915mg/L。在处理的幼虫中观察到行为改变,如兴奋、坐立不安、颤抖、痉挛然后瘫痪,说明这两种油可能对其神经肌肉系统产生了影响。显微观察处理幼虫的形态改变发现,与对照相比,大多数器官的外观正常,只是肛鳃略为内收缩而引起结构畸形,提示肛腮可能是这两种油的作用位点,腮的功能异常引起了幼虫死亡。这两种油品可开发用作防治蚊虫的新型杀幼虫药剂。

关键词：埃及伊蚊松树肉桂杀幼虫潜力肛腮痉挛

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Phytochemical and in vitro biological investigations of methanolic extracts of Enhydra fluctuans Lour

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Asian Pacific Journal of Tropical Biomedicine 2014年第4期4卷 299-305页

作者： Sourov Kuri Mustahsan Billah S.M.Masud Rana Zannatul naim.Mahmodul Islam Hasanuzzaman Ramjan Ali Rana Banik Department of Pharmacy Noakhali Science and Technology University Department of Pharmacy Atish Dipankar University of Science and Technology

Objective:To study the phytochemical and biological properties(antioxidant,anthelmintic and thrombolytic)of methanolic extracts of Enhydra fluctuant Lour.,a plant belonging to the Asteraceae ***:The phytochemical evaluation was carried out by qualitative *** vitro antioxidant activity of extract was studied using free radical scavenging assay,ability of reduction,total phenol and total flavonoid contents determination *** anthelmintic activity was determined using paralysis and death time of Pheretima posthuma(earthworm)and thrombolytic activity by clot disruption ***:The phytochemical evaluation showed significant presence of flavonoids,triterpenes,carbohydrate,reducing sugars,saponins,phenols,diterpenes,protein and *** antioxidant activity was found significant[IC_(50)(135.20±036)μg/mL]as compared to ascorbic acid[(130.00±0.76)μg/mL].The reducing power was increased with *** phenol and total flavonoid contents were(153.08±0.38)mg/mL and(172.04±0.56)mg/mL *** paralysis and death time of earthworms for different concentrations of extract were determined and compared with *** results showed that 10 mg/mL of the crude extract had similar effect with ***,the crude extract showed a concentration depended relationship with its anthelmintic *** clot lysis activity of crude extract was compared to the standard streptokinase's clot lysis(40.13%)activity and found significant(31%).Conclusions:The study proves that the crude methanolic extract of Enhydra fluctuant Lour,has significant antioxidant,anthelmintic and thrombolytic activity containing wide range of phytochemicals.

关键词： Enhydra fluctuans Lour. Phytochemicals Antioxidant DPPH radical scavenging Pheretima posthuma Streptokinase

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