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Bioinspired design of integral molded Janus silk fibroin-MXene evaporator for efficient solar vapor generation

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Nano Research 2024年第4期17卷 2824-2835页

作者： Ling-Qing Kong Zhi-Cheng Zeng Guang-Zong Min Zhao-hui Meng Guo-Qing Meng Xiao-Xiao Guo nai-Bo Lin Xiang-yang Liu The Higher Educational Key Laboratory for Biomedical Engineering of Fujian Province Research Center of Biomedical Engineering of XiamenDepartment of BiomaterialsCollege of MaterialsXiamen UniversityXiamen 361005China The State Key Laboratory of Marine Environmental Science(MEL) College of Ocean and Earth SciencesXiamen UniversityXiamen 361005China

Solar vapor generation is a promising sustainable technology that uses solar distillation to produce fresh water from seawater and wastewater,helping relieve global water resource ***,inspired by naturally grown integrally molded mulberry leaves with a Janus hydrophilic and hydrophobic structure,a novel,simple,and efficient integrated molding method is proposed to break through the limitations of the traditional split manufacturing strategy and realizes the integrated formation of Janus *** on the spontaneous sedimentation characteristics of MXene in silk fibroin solution and its regulation of mesoscopic structure and hydrophilicity of silk fibroin,layered structures with different compositions and hydrophilicities were obtained in one ***,ethanol and glutaraldehyde were added to construct a physical crystallization-chemical crosslinking dual stabilization structure in silk *** evaporator has the evaporation rate of 3.07 kg·m^(-2)·h^(-1) and the efficiency of 86.8%under 1 sun and maintains high evaporation performance under various extreme test conditions including vigorous washing,repeated compression,and high-intensity ultraviolet(UV)***,the evaporator performs well in practical application scenarios,its evaporation rate in the simulated Dead Sea seawater exceeds 2.13 kg·m^(-2)·h^(-1),and more than 99.9%of the salt,heavy metal ions,oil pollution,and dyes are purified.

关键词： silk fibroin MXene bioinspired integrated molding Janus structure solar vapor generation

Efficacy and Safety of Bufei Jiedu Granules in Treating Multidrug-Resistant Pulmonary Tuberculosis:A Multi-center,Double-Blinded and Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第7期30卷 579-587页

作者： ZHANG Shao-yan QIU Lei ZHANG Shun-xian XIAO He-ping CHU nai-hui ZHANG Xia ZHANG hui-qiang ZHENG Pei-yong ZHANG hui-yong LU Zhen-hui Institute of Respiratory Diseases Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai200032China Clinical Research Center Shanghai University of Traditional Chinese MedicineShanghai200032China Department of Tuberculosis Shanghai Pulmonary HospitalTongji UniversityShanghai200433China Department of Tuberculosis Beijing Chest HospitalCapital Medical UniversityBeijing101100China Department of Tuberculosis the Second Hospital of NanjingNanjing210003China Department of Tuberculosis the First Hospital Affiliated to Xinxiang Medical CollegeXinxiangHenan Province453100China

Objective: To assess the efficacy and safety of Bufei Jiedu(BFJD) Granules as adjuvant therapy for patients with multidrug-resistant pulmonary tuberculosis(MDR-PTB). Methods: A large-scale, multi-center, double-blinded, and randomized controlled trial was conducted in 18 sentinel hospitals in China from December 2012 to December 2016. A total of 312 MDR-PTB patients were randomly assigned to BFJD Granules or placebo groups(1:1) using a stratified randomization method, which both received the long-course chemotherapy regimen for 18 months(6 Am-Lfx-P-Z-Pto, 12 Lfx-P-Z-Pto). Meanwhile, patients in both groups also received BFJD Granules or placebo twice a day for a total of 18 months, respectively. The primary outcome was cure rate. The secondary outcomes included time to sputum-culture conversion, changes in lung cavities and quality of life(QoL) of patients. Adverse reactions were monitored during and after the trial. Results: A total of 216 cases completed the trial, 111 in the BFJD Granules group and 105 in the placebo group. BFJD Granules, as adjuvant treatment, increased the cure rate by 13.6% at the end of treatment, compared with the placebo(58.4% vs. 44.8%, P=0.02), and accelerated the median time to sputum-culture conversion(5 months vs. 11 months). The cavity closure rate of the BFJD Granules group(50.6%, 43/85) was higher than that of the placebo group(32.1%, 26/81;P=0.02) in patients who completed the treatment. At the end of the intensive treatment, according to the 36-item Short Form, the BFJD Granules significantly improved physical functioning, general health, and vitality of patients relative to the placebo group(all P<0.01). Overall, the death rates in the two groups were not significantly different;5.1%(8/156) in the BFJD Granules group and 2.6%(4/156) in the placebo group. Conclusions: Supplementing BFJD Granules with the long-course chemotherapy regimen significantly increased the cure rate and cavity closure rate, and rapidly improved QoL of pati

关键词： alternative medicine Chinese herbal formula Bufei Jiedu Granules multidrug-resistant tuberculosis long-course chemotherapy regimen randomized controlled trial

Tumor microenvironment-responsive arsenic-loaded layered double hydroxides film with synergistic anticancer and bactericidal activity

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Rare Metals 2024年第3期43卷 1207-1221页

作者： Shun Xing Dong-hui Wang Hai-Feng Zhang Li-Dan Liu Cheng-Ce Li Chao Wei Jun-Yu Liu nai-Jian Ge Xuan-Yong Liu State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai200050China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing100049China Intervention Center Eastern Hepatobiliary Surgery HospitalThe Third Affiliated Hospital of Naval Medical UniversityShanghai200438China School of Health Sciences and Biomedical Engineering Hebei University of TechnologyTianjin300130China

Malignant obstruction makes gallbladder cancer have a high mortality ***-titanium alloy(nitinol)stents are commonly used as a local intervention to maximize patient survival time,but the stents lack antitumor and antibacterial capacity and are vulnerable to secondary ***-based drugs show good therapeutic promise against gallbladder *** meet clinical *** layered double hydroxides(LDHs)film is constructed on the nitinol,whose arsenite loading amounts rose by 60%after simple heat treatment compared with the conventional anion-exchange *** addition,calcination promotes the dissolution of nickel ions from the LDHs lattice,resulting in a powerful synergistic killing effect on tumor cells together with the released *** importantly,the calcined arsenic-loaded LDHs are sensitive to the acidic microenvironment of tumor tissues,which presents a much lower arsenic and nickel release amount in the normal tissues,guaranteeing its ***,the vertically sharp LDHs nanosheets can synergize with arsenic to achieve effective physical cleavage and chemical killing of adherent and planktonic *** short,we attempt to use arsenic drugs for local interventions and reasonably avoid their toxic side effects,which provides a new design idea for nitinol stents applied in the treatment of gallbladder cancer.

关键词： Nitinol Layered double hydroxides Arsenic Gallbladder cancer

Decoding topological XYZ^(2) codes with reinforcement learning based on attention mechanisms

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Chinese Physics B 2024年第6期33卷 262-270页

作者：陈庆辉姬宇欣王柯涵马鸿洋纪乃华 School of Information and Control Engineering Qingdao University of TechnologyQingdao 266033China School of Sciences Qingdao University of TechnologyQingdao 266033China

Quantum error correction, a technique that relies on the principle of redundancy to encode logical information into additional qubits to better protect the system from noise, is necessary to design a viable quantum computer. For this new topological stabilizer code-XYZ^(2) code defined on the cellular lattice, it is implemented on a hexagonal lattice of qubits and it encodes the logical qubits with the help of stabilizer measurements of weight six and weight two. However topological stabilizer codes in cellular lattice quantum systems suffer from the detrimental effects of noise due to interaction with the environment. Several decoding approaches have been proposed to address this problem. Here, we propose the use of a state-attention based reinforcement learning decoder to decode XYZ^(2) codes, which enables the decoder to more accurately focus on the information related to the current decoding position, and the error correction accuracy of our reinforcement learning decoder model under the optimisation conditions can reach 83.27% under the depolarizing noise model, and we have measured thresholds of 0.18856 and 0.19043 for XYZ^(2) codes at code spacing of 3–7 and 7–11, respectively. our study provides directions and ideas for applications of decoding schemes combining reinforcement learning attention mechanisms to other topological quantum error-correcting codes.

关键词： quantum error correction topological quantum stabilizer code reinforcement learning attention mechanism

电动汽车电池温度一致性与驾驶行为关联特性研究

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中国公路学报 2024年第3期37卷 216-230页

作者：张晖李少鹏丁乃侃武汉理工大学智能交通系统研究中心湖北武汉430063 武汉理工大学交通信息与安全教育部工程研究中心湖北武汉430063

为实现融合车辆运行状态的电池温度不一致性的精准评估诊断,设计并开展电动汽车自然驾驶试验,利用长周期、精细化的车辆运行数据,从微观运行片段的角度探究了电池温度一致性与驾驶行为的关联特性。通过驾驶人踩/松踏板的驾驶行为将车辆... 详细信息

为实现融合车辆运行状态的电池温度不一致性的精准评估诊断,设计并开展电动汽车自然驾驶试验,利用长周期、精细化的车辆运行数据,从微观运行片段的角度探究了电池温度一致性与驾驶行为的关联特性。通过驾驶人踩/松踏板的驾驶行为将车辆运行过程划分为A、B、C、D四类微观片段。分别针对4类片段,通过计算最大信息系数(Maximum Information Coefficient, MIC)得到了各驾驶行为参数与探针温度变异系数(Variation Coefficient of Probe Temperature, VCPT)的相关性,利用随机森林模型分析了驾驶行为参数对VCPT的重要性及影响机理,利用数据分组统计计算了驾驶行为参数对VCPT的量化影响效应。研究结果表明:驾驶行为参数与电池温度一致性具有弱相关性,且其对电池温度一致性的影响是非线性且非单调的;总体上车速类参数与电池温度一致性的相关性强于加速度和踏板类参数;对VCPT回归预测最重要的4项驾驶行为参数中,4类片段下均包含最大车速,B、C、D三类片段下均包含最大负向加速度;相比于高车速和高车速波动,高减速度驾驶行为引起的温度不一致性增幅是最显著的,4类片段下VCPT促进效应最显著的驾驶行为参数分别是最大负向加速度、平均负向加速度、最大负向加速度、车速标准差,其参数值85%分位点以上对应的VCPT均值比15%分位点以下的分别大9.44%、20.36%、13.05%、16.37%。研究结果可以支撑基于驾驶场景自适应阈值的电池温度不一致性评估诊断方法的提出,进而提高电动汽车电池安全预警准确率。

关键词：汽车工程电池安全最大信息系数电池温度一致性电动汽车驾驶行为

考虑加载次序影响的沥青非线性疲劳损伤累积研究

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工程力学 2024年第5期41卷 68-76页

作者：房辰泽冷真郭乃胜李辉蒋继望陆国阳王昊鹏大连海事大学交通运输工程学院辽宁大连116026 香港理工大学土木及环境工程学系中国香港九龙999077 诺丁汉大学诺丁汉交通工程中心英国诺丁汉NG72RD

变幅加载下沥青的疲劳损伤累积具有明显的非线性特征,传统的Miner’s线性疲劳损伤累积准则无法表征不同变幅加载次序下沥青的非线性疲劳损伤累积(NLFDA)。该研究旨在建立考虑加载次序影响的NLFDA模型,准确表征加载次序对沥青疲劳损伤累... 详细信息

变幅加载下沥青的疲劳损伤累积具有明显的非线性特征,传统的Miner’s线性疲劳损伤累积准则无法表征不同变幅加载次序下沥青的非线性疲劳损伤累积(NLFDA)。该研究旨在建立考虑加载次序影响的NLFDA模型,准确表征加载次序对沥青疲劳损伤累积的影响。通过开展应力控制的沥青恒幅加载疲劳试验,采用耗散伪应变能(DPSE)表征沥青疲劳损伤,分析恒幅加载下沥青的疲劳损伤累积规律;采用低-高和高-低两种加载次序,开展应力控制的沥青变幅加载疲劳试验,分析变幅加载下沥青的疲劳损伤累积规律;基于损伤等效准则,建立考虑加载次序影响的NLFDA模型,分析加载次序对疲劳损伤累积的影响。结果表明:应力控制模式下的沥青疲劳损伤,呈先缓慢后急剧的非线性增加演化趋势;恒幅加载下沥青疲劳损伤服从Miner’s准则发生线性累积,且累积寿命分数等于1;变幅加载下沥青疲劳损伤不服从Miner’s准则而发生非线性累积。低-高和高-低变幅加载次序下,沥青累积疲劳寿命随一级寿命分数的增大而分别增加和减小,累积寿命分数分别大于1和小于1;建立的NLFDA模型可克服Miner’s准则缺陷,并较为准确地表征加载次序对沥青疲劳损伤累积的影响。

关键词：道路工程沥青材料非线性疲劳损伤累积加载次序耗散伪应变能疲劳寿命

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禽流感的流行现状及中草药治疗

畜牧兽医杂志 2003年第4期22卷 14-15页

作者：肖乃志杨惠萍李树银杨凌职业技术学院陕西杨凌712100 三原县畜牧兽医站

调查了陕西省禽流感的流行情况,总结出近几年该病发生的特点、临床特征,并提出切实可行的综合防治对策。

关键词：禽流感流行现状中草药治疗发生特点临床症状

Zn_(3)(As_(1-x)P_(x))_(2)纳米结构制备及光谱特性研究

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光谱学与光谱分析 2024年第7期44卷 1934-1939页

作者：王浩孙乃坤庞超王志帅陈上峰李武田辉岱钦沈阳理工大学理学院辽宁沈阳110159

Zn_(3)As_(2)与Zn_(3)P_(2)具有相同的伪立方晶格结构,它们具有较高的电子迁移率、较窄的直接带隙和良好的空气稳定性,在光电器件领域呈现出广泛的应用前景。目前关于Zn_(3)As2-Zn_(3)P_(2)固溶体纳米结构的研究相对较少,采用高气压烧... 详细信息

Zn_(3)As_(2)与Zn_(3)P_(2)具有相同的伪立方晶格结构,它们具有较高的电子迁移率、较窄的直接带隙和良好的空气稳定性,在光电器件领域呈现出广泛的应用前景。目前关于Zn_(3)As2-Zn_(3)P_(2)固溶体纳米结构的研究相对较少,采用高气压烧结技术得到Zn_(3)(As_(1-x)P_(x))_(2)(x=0、0.05、0.1)母合金,再利用化学气相沉积方法合成出多种形态的Zn_(3)(As_(1-x)P_(x))_(2)纳米结构,包括宏观尺寸的纳米带(长度3~10 mm;宽度1~4 mm;厚度约20μm)、纳米帆、纳米棒及纳米银簪等。系统的研究了P掺杂对相组成、元素含量、微结构以及光谱特性的影响。X射线衍射(XRD)结果表明,Zn_(3)(As_(1-x)P_(x))_(2)宏观纳米带样品的主相为α′相,随着P掺杂含量的增加,(224)衍射峰向右发生偏移,表明晶格常数减小。电子能谱分析显示P理论值(光致发光光谱)掺杂含量值x=0.05和x=0.1的Zn_(3)(As_(1-x)P_(x))_(2)母合金纳米带中P的实际含量分别为x=0.026及x=0.062。微结构分析表明,Zn_(3)As_(2)宏观纳米带的生长模式为沿〈221〉晶面菱形层状生长,P掺杂使纳米带的宏观尺寸减小,生长模式由菱形层状生长转变为纳米颗粒堆积层状生长。纳米带样品的拉曼光谱在79、97、198、320、428和1107 cm^(-1)出现特征峰,P掺杂导致拉曼光谱中1107 cm^(-1)特征峰发生蓝移,傅里叶红外光谱(FTIR)中1101和1599 cm^(-1)特征峰与PL谱中的300、422和635 nm特征峰也发生蓝移。Zn_(3)As_(2)与Zn_(3)(As_(0.974)P_(0.026))_(2)纳米带光电流与电压的线性关系良好,存在较好的欧姆特性,P掺杂后的Zn_(3)(As_(0.974)P_(0.026))2纳米带在900 nm条件下的光响应最为敏感。

关键词： Zn_(3)(As_(1-x)P_(x))_(2) Zn_(3)As_(2) 纳米带固溶体

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手术器械预处理时机与清洗质量的关联

中华医院感染学杂志 2024年第8期34卷 1268-1271页

作者：李彦琼陈耐寒胡星辉撒亚莲杨红兰云南省第一人民医院昆明理工大学附属医院消毒供应中心云南昆明650032 云南省第一人民医院昆明理工大学附属医院临床医学研究中心云南昆明650032 中国人民解放军联勤保障部队第九二六医院消毒供应中心云南开远661600

目的对比手术器械手术中、手术后和清洗前三个时机的预处理效果和对器械清洗质量的影响。方法分别选取云南省第一人民医院2023年5月-8月手术时长不同的器械共180套,按照预处理时机分为三组,对器械进行预处理,同样操作进行后续清洗流程,... 详细信息

目的对比手术器械手术中、手术后和清洗前三个时机的预处理效果和对器械清洗质量的影响。方法分别选取云南省第一人民医院2023年5月-8月手术时长不同的器械共180套,按照预处理时机分为三组,对器械进行预处理,同样操作进行后续清洗流程,通过ATP生物荧光检测法、蛋白残留测定法评价不同预处理时机的器械清洗质量,通过蓝点试验法检测器械锈蚀变化情况。结果ATP生物荧光检测、蛋白残留量检测器械手术中、手术后预处理的清洗合格率均高于清洗前(P<0.001);蓝点试验检测器械手术中、手术后预处理的锈蚀合格率均高于清洗前(P<0.001);手术时间越长,器械的锈蚀率就越高,手术中预处理的器械锈蚀合格率高于手术后和清洗前(P<0.001)。结论手术器械在手术中、手术后立即进行预处理,能够提升清洗质量,减少器械锈蚀,尤其是使用于手术时长大于2h的器械,应在手术中就及时进行预处理。

关键词：预处理时机手术器械清洗质量蓝点试验关联