检索结果-南通市图书馆

An abundant valuable resource for salt-tolerance allele hunting in rice

在线全文

学校读者我要写书评

暂无评论

Plant Communications 2024年第4期5卷 127-128页

作者： nai-qian dong Hong-Xuan Lin National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China University of the Chinese Academy of Sciences Beijing 100049China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China

Soil salinity is a major abiotic stressor that limits plant growth and crop productivity ***,soil salinity is predictably increasing owing to global climate change,over-fertilization,and various farm irrigation ***,there are more than 833 million hectares of salt-affected soils around the globe(8.7% of the planet),accounting for approximately 20%–50% of irrigated soils and posing a significant threat to food production and security for over 1.5 billion people worldwide as a result of salt-induced land degradation(FAO,2021;https://***/global-soil-partnership/resources/highlights/detail/en/c/1445579/).

关键词： soil salinity abundant

Tillering and small grain 1 dominates the tryptophan aminotransferase family required for local auxin biosynthesis in rice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2020年第5期62卷 581-600页

作者： Tao Guo Ke Chen nai-qian dong Wang-Wei Ye Jun-Xiang Shan Hong-Xuan Lin National Key Laboratory of Plant Molecular Genetics CAS Centre for Excellence in Molecular Plant Sciences and Collaborative Innovation Center of Genetics&DevelopmentShanghai Institute of Plant Physiology&EcologyShanghai Institute for Biological SciencesChinese Academy of SciencesShanghai 200032China University of the Chinese Academy of Sciences Beijing 100049China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China

Auxin is a crucial phytohormone,controlling multiple aspects of plant growth and responses to the changing ***,the role of local auxin biosynthesis in specific developmental programs remains unknown in *** study characterized the rice tillering and small grain 1(tsg1)mutant,which has more tillers but a smaller panicle and grain size resulting from a reduction in endogenous ***1 encodes a tryptophan aminotransferase that is allelic to the FISH BONE(FIB)*** tsg1 mutant showed hypersensitivity to indole-3-acetic acid and the competitive inhibitor of aminotransferase,***1 knockout resulted in an increased tiller number but reduction in grain number and size,and decrease in ***,deletion of the TSG1 homologs OsTAR1,Os TARL1,and OsTARL2 caused no obvious changes,although the phenotype of the TSG1/Os TAR1 double mutant was intensified and infertile,suggesting gene redundancy in the rice tryptophan aminotransferase ***,TSG1 and Os TAR1,but not Os TARL1 and OsTARL2,displayed marked aminotransferase ***,subcellular localization was identified as the endoplasmic reticulum,while phylogenetic analysis revealed functional divergence of TSG1 and OsTAR1 from OsTARL1 and *** findings suggest that TSG1 dominates the tryptophan aminotransferase family,playing a prominent role in local auxin biosynthesis in rice.

关键词： grain local auxin

A QTL GN1.1, encoding FT-L1, regulates grain number and yield by modulating polar auxin transport in rice

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2024年第10期66卷 2158-2174页

作者： Huai-Yu Zhao Jun-Xiang Shan Wang-Wei Ye nai-qian dong Yi Kan Yi-Bing Yang Hong-Xiao Yu Zi-Qi Lu Shuang-Qin Guo Jie-Jie Lei Ben Liao Hong-Xuan Lin National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China University of the Chinese Academy of Sciences Beijing 100049China Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510642China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China

Rice grain number is a crucial agronomic trait impacting yield. In this study, we characterized a quantitative trait locus(QTL), GRAIN NUMBER 1.1(GN1.1), which encodes a Flowering Locus T-like1(FT-L1) protein and acts as a negative regulator of grain number in rice. The elite allele GN1.1^(B),derived from the Oryza indica variety, BF3-104,exhibits a 14.6% increase in grain yield compared with the O. japonica variety, Nipponbare, based on plot yield tests. We demonstrated that GN1.1 interacted with and enhanced the stability of ADP-ribosylation factor(Arf)-GTPase-activating protein(Gap), OsZAC. Loss of function of OsZAC results in increased grain number. Based on our data, we propose that GN1.1^(B)facilitates the elevation of auxin content in young rice panicles by affecting polar auxin transport(PAT) through interaction with OsZAC. Our study unveils the pivotal role of the GN1.1 locus in rice panicle development and presents a novel, promising allele for enhancing rice grain yield through genetic improvement.

关键词： auxin GN1.1 grain number OsZAC QTL mapping

A TT1–SCE1 module integrates ubiquitination and SUMOylation to regulate heat tolerance in rice

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2024年第12期17卷 1899-1918页

作者： Hong-Xiao Yu Ying-Jie Cao Yi-Bing Yang Jun-Xiang Shan Wang-Wei Ye nai-qian dong Yi Kan Huai-Yu Zhao Zi-Qi Lu Shuang-Qin Guo Jie-Jie Lei Ben Liao Hong-Xuan Lin National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China University of the Chinese Academy of Sciences Beijing 100049China Joint Center for Single Cell Biology School of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510642China These authors contributed equally to this article

Heat stress poses a significant threat to grain *** anα2 subunit of the 26S proteasome,TT1 has been shown to act as a critical regulator of rice heat ***,the heat tolerance mechanisms mediated by TT1 remain *** this study,we unveiled that small ubiquitin-like modifier(SUMO)-conjugating enzyme 1(SCE1),which interacts with TT1 and acts as a downstream component of TT1,is engaged in TT1-mediated 26S proteasome *** showed that SCE1 functions as a negative regulator of heat tolerance in rice,which is associated with its ubiquitination ***,we observed that small heat-shock proteins(sHSPs)such as Hsp24.1 and Hsp40 can undergo SUMOylation mediated by SCE1,leading to increased accumulation of sHSPs in the absence of *** protein levels of SCE1 significantly enhanced grain yield under high-temperature stress by improving seed-setting rate and rice grain filling *** together,these results uncover the critical role of SCE1 in the TT1-mediated heat tolerance pathway by regulating the abundance of sHSPs and SUMOylation,and ultimately modulating rice heat *** findings underscore the great potential of the TT1–SCE1 module in improving the heat tolerance of crops.

关键词： rice heat tolerance ubiquitination SUMOylation heat-shock protein

Translational Regulation of Plant Response to High Temperature by a Dual-Function tRNAHls Guanylyltransferase in Rice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2019年第8期12卷 1123-1142页

作者： Ke Chen Tao Guo Xin-Min Li Yi-Min Zhang Yi-Bing Yang Wang-Wei Ye nai-qian dong Chuan-Lin Shi Yi Kan You-Huang Xiang Hai Zhang Ya-Chao Li Ji-Ping Gao Xuehui Huang qiang Zhao Bin Han Jun-Xiang Shan Hong-Xuan Lin National Key Laboratory of Plant Molecular Genetics CAS Centre for Excellence in Molecular Plant Sciences and Collaborative Innovation Center of Genetics & DevelopmentShanghai Institute of Plant Physiology & EcologyShanghai Institute for Biological SciencesChinese Academic of SciencesShanghai 200032China University of the Chinese Academy of Sciences Beijing 100049China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China National Center for Gene Research CAS Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 200233China College of Life and Environmental Sciences Shanghai Normal UniversityShanghai 200234China

As sessile organisms,plants have evolved numerous strategies to acclimate to changes in environmental ***,the molecular basis of this acclimation remains largely *** this study we identified a tRNAHis guanylyltransferase,AET1,which contributes to the modification of pre-tRNAH,s and is required for normal growth under high-temperature conditions in ***,AET1 possibly interacts with both RACK1A and elF3h in the endoplasmic ***,AET1 can directly bind to OsARF mRNAs including the uORFs of OsARF19 and OsARF23,indicating that AET1 is associated with translation ***,polysome profiling assays suggest that the translational status remains unaffected in the aet1 mutant,but that the translational efficiency of OsARF19 and OsARF23 is reduced;moreover,OsARF23 protein levels are obviously decreased in the aet1 mutant under high temperature,implying that AET1 regulates auxin signaling in response to high *** provide new insights into the molecular mechanisms whereby AET1 regulates the environmental temperature response in rice by playing a dual role in tRNA modification and translational control.

关键词： rice translation regulation tRNA modification auxin signaling environmental temperature

Anα/βhydrolase family member negatively regulates salt tolerance but promotes flowering through three distinct functions in rice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2022年第12期15卷 1908-1930页

作者： You-Huang Xiang Jia-Jun Yu Ben Liao Jun-Xiang Shan Wang-Wei Ye nai-qian dong Tao Guo Yi Kan Hai Zhang Yi-Bing Yang Ya-Chao Li Huai-Yu Zhao Hong-Xiao Yu Zi-Qi Lu Hong-Xuan Lin National Key Laboratory of Plant Molecular Genetics CAS Centre for Excellence in Molecular Plant Sciences and Collaborative Innovation Center of Genetics&DevelopmentShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510642China University of the Chinese Academy of Sciences Beijing 100049China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China

Ongoing soil salinization drastically threatens crop growth,development,and yield *** is therefore crucial that we improve salt tolerance in rice by exploiting natural genetic ***,many salt-responsive genes confer undesirable phenotypes and therefore cannot be effectively applied to practical agricultural *** this study,we identified a quantitative trait locus for salt tolerance from the African rice species Oryza glaberrima and named it as Salt Tolerance and Heading Date 1(STH1).We found that STH1 regulates fatty acid metabolic homeostasis,probably by catalyzing the hydrolytic degradation of fatty acids,which contributes to salt ***,we demonstrated that STH1 forms a protein complex with D3 and a vital regulatory factor in salt tolerance,OsHAL3,to regulate the protein abundance of OsHAL3 via the 26S proteasome ***,we revealed that STH1 also serves as a co-activator with the floral integrator gene Heading date 1 to balance the expression of the florigen gene Heading date 3a under different circumstances,thus coordinating the regulation of salt tolerance and heading ***,the allele of STH1 associated with enhanced salt tolerance and high yield is found in some African rice accessions but barely in Asian *** of the STH1HP46 allele from African rice into modern rice cultivars is a desirable approach for boosting grain yield under salt ***,our discoveries not only provide conceptual advances on the mechanisms of salt tolerance and synergetic regulation between salt tolerance and flowering time but also offer potential strategies to overcome the challenges resulted from increasingly serious soil salinization that many crops are facing.

关键词： rice salt tolerance flowering time grain yield fatty acid

Discovery of a new family member of arsenic–vanadium polyoxometalates with high catalytic performance for one-pot coupling of CO2, epoxides and amines

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tungsten 2025年第1期7卷 80-87页

作者： Fang-qian Wang Yin Zhang Wei-Wei Wang Mei-qian Fu Hong-Bing Mo Wei-dong Yu Chao Liu Jun Yan College of Chemistry and Chemical Engineering Central South University Junior Education Department Changsha Normal University School of Science Hunan University of Technology and Business

Arsenic-vanadium polyoxometalates（POMs） represent a family of tremendous potential catalysts owing to their peculiar physical and chemical *** in CO2conversion,using POMs to catalyze the conversion of CO2and epoxide into chemical intermediates is the research ***,A new family number of arsenic-vanadium POMs,[N（CH3）4]4[As8V12O38（H2O）]·2H2O({As8V12O38}),was reported and characterized by single-crystal X-ray diffraction,fourier transform infrared spectroscopy,X-ray photoelectron spectroscopy,*** from other allotropicity,{As8V12O38}shows a different structure pattern with an I-43d *** obtained {As8V12O38} was employed as a catalyst for the *** initial catalytic reaction confirmed that {As8V12O38} can catalyze the formation of epoxy carbonate by using 1.01 kPa CO2and epoxide at 70℃.Furtherly,when added amine in the catalytic system,oxazolidinone could be obtained by high yields,which provides an efficient way to convert CO2into profitable ***,a possible catalytic reaction mechanism was proposed by using different characterization analyses.{As8V12O38} first catalyzes the epoxide and CO2to form an epoxy carbonate and then catalyzes epoxy carbonate and benzylamine into oxazolidinone.

关键词： Arsenic CO2 conversion Oxazolidinone Polyoxometalates Vanadium

AZD1775 synergizes with SLC7A11 inhibition to promote ferroptosis

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Life Sciences 2025年第1期68卷 204-218页

作者： Chen Xiong Hong Ling Yingdan Huang Hanzhi dong Bangxiang Xie qian Hao Xiang Zhou Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences Fudan University Department of Oncology Shanghai Medical CollegeFudan University Department of Breast Surgery Fudan University Shanghai Cancer CenterFudan University Department of Oncology First Affiliated Hospital of Nanchang University Beijing Institute of Hepatology Beijing Youan HospitalCapital Medical University Beijing Engineering Research Center for Precision Medicine and Transformation of Hepatitis and Liver Cancer Key Laboratory of Breast Cancer in Shanghai Fudan University Shanghai Cancer CenterFudan University Shanghai Key Laboratory of Medical Epigenetics International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology)Institutes of Biomedical SciencesFudan University

Tumor suppressor p53-mediated cell cycle arrest and DNA damage repair may exert cytoprotective effects against cancer therapies, including WEE1 inhibition. Considering that p53 activation can also lead to multiple types of cell death, the role of this tumor suppressor in WEE1 inhibitor-based therapies remains disputed. In this study, we reported that nucleolar stress-mediated p53 activation enhanced the WEE1 inhibitor AZD1775-induced ferroptosis to suppress lung cancer growth. Our findings showed that AZD1775 promoted ferroptosis by blocking cystine uptake, an action similar to that of Erastin. Meanwhile, inhibition of WEE1 by the WEE1 inhibitors or si RNAs induced compensatory upregulation of SLC7A11, which conferred resistance to ferroptosis. Mechanistically, AZD1775 prevented the enrichment of H3K9me3, a histone marker of transcriptional repression, on the SLC7A11 promoter by repressing the expression of the histone methyltransferase SETDB1, thereby enhancing NRF2-mediated SLC7A11 transcription. This finding was also validated using the H3K9me3 inhibitor BRD4770. Remarkably, we found that the nucleolar stress-inducing agent Actinomycin D(Act. D) inhibited SLC7A11 expression by activating p53, thus augmenting AZD1775-induced ferroptosis. Moreover, the combination of AZD1775 and Act. D synergistically suppressed wild-type p53-harboring lung cancer cell growth both in vitro and in vivo. Altogether, our study demonstrates that AZD1775 promotes ferroptosis by targeting cystine uptake but also mediates the adaptive activation of SLC7A11 through the WEE1-SETDB1 cascade and NRF2-induced transcription, and inhibition of SLC7A11 by Act. D boosts the anti-tumor efficacy of AZD1775 by enhancing ferroptosis in cancers with wild-type p53.

关键词： p53 NRF2 SLC7A11 WEE1 AZD1775 ferroptosis nucleolar stress

Overview of in-situ oxygen production technologies for lunar resources

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 233-255页

作者： Youpeng Xu Sheng Pang Liangwei Cong Guoyu qian dong Wang Laishi Li Yusheng Wu Zhi Wang College of Materials Science and Engineering Shenyang University of TechnologyShenyang 110870China CAS Key Laboratory of Green Process and Engineering National Engineering Research Center for Green Recycling of Strategic Metal ResourcesInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China Innovation Academy for Green Manufacture Chinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049China

The rich resources and unique environment of the Moon make it an ideal location for human expansion and the utilization of extraterrestrial ***,crucial for supporting human life on the Moon,can be extracted from lunar regolith,which is highly rich in oxygen and contains polymetallic *** oxygen and metal extraction can be achieved using existing metallurgical ***,the ample reserves of water ice on the Moon offer another means for oxygen *** paper offers a detailed overview of the leading technologies for achieving oxygen production on the Moon,drawing from an analysis of lunar resources and environmental *** delves into the principles,processes,advantages,and drawbacks of water-ice electrolysis,two-step oxygen production from lunar regolith,and one-step oxygen production from lunar *** two-step methods involve hydrogen reduction,carbothermal reduction,and hydrometallurgy,while the one-step methods encompass fluorination/chlorination,high-temperature decomposition,molten salt electrolysis,and molten regolith electrolysis(MOE).Following a thorough comparison of raw materials,equipment,technology,and economic viability,MOE is identified as the most promising approach for future in-situ oxygen production on the *** the corrosion characteristics of molten lunar regolith at high temperatures,along with the Moon's low-gravity environment,the development of inexpensive and stable inert anodes and electrolysis devices that can easily collect oxygen is critical for promoting MOE technology on the *** review significantly contributes to our understanding of in-situ oxygen production technologies on the Moon and supports upcoming lunar exploration initiatives.

关键词： lunar resources in-situ oxygen production space metallurgy molten lunar regolith electrolysis