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A noval iron-capturing nanocomposites against biofilms for disrupting bacterial nutritional balance

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Science China Chemistry 2024年第6期67卷 1760-1761页

作者： Jinying lin Qihang Ding yao Sun Department of Oral Implantology Jilin Provincial Key Laboratory of Tooth Development and Bone RemodelingSchool of StomatologyJilin UniversityChangchun130021China Department of Chemistry Korea UniversitySeoul02841Korea National Key Laboratory of Green Pesticide International Joint Research Center for Intelligent Biosensor Technology and HealthCollege of ChemistryCentral China Normal UniversityWuhan430079China

Currently,the escalating crisis of bacterial infections and antibiotic resistance poses a significant global public health challenge[1-3].This situation has driven the search for novel antimicrobial ***,a crucial micr... 详细信息

关键词： metabolism resistance balance

Piezotronic neuromorphic devices:principle,manufacture,and applications

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International Journal of Extreme Manufacturing 2024年第3期6卷 363-385页

作者： Xiangde lin Zhenyu Feng yao Xiong Wenwen Sun Wanchen yao Yichen Wei Zhong lin Wang Qijun Sun Department of Research Shanghai University of Medicine and Health Sciences Affiliated Zhoupu HospitalShanghai 201318People’s Republic of China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400People’s Republic of China Center on Nanoenergy Research School of Chemistry and Chemical EngineeringGuangxi UniversityNanning 530004People’s Republic of China Shandong Zhongke Naneng Energy Technology Co. LtdDongying 257061People’s Republic of China Georgia Institute of Technology AtlantaGA 30332-0245United States of America

With the arrival of the era of artificial intelligence(AI)and big data,the explosive growth of data has raised higher demands on computer hardware and *** techniques inspired by biological nervous systems are expected to be one of the approaches to breaking the von Neumann *** neuromorphic devices modulate electrical transport characteristics by piezopotential and directly associate external mechanical motion with electrical output signals in an active manner,with the capability to sense/store/process information of external *** this review,we have presented the piezotronic neuromorphic devices(which are classified into strain-gated piezotronic transistors and piezoelectric nanogenerator-gated field effect transistors based on device structure)and discussed their operating mechanisms and related manufacture ***,we summarized the research progress of piezotronic neuromorphic devices in recent years and provided a detailed discussion on multifunctional applications,including bionic sensing,information storage,logic computing,and electrical/optical artificial ***,in the context of future development,challenges,and perspectives,we have discussed how to modulate novel neuromorphic devices with piezotronic effects more *** is believed that the piezotronic neuromorphic devices have great potential for the next generation of interactive sensation/memory/computation to facilitate the development of the Internet of Things,AI,biomedical engineering,etc.

关键词： piezotronics neuromorphic devices strain-gated transistors piezoelectric nanogenerators synaptic transistors

Electron-microscopical visualization on the interfacial and crystallographic structures of lithium metal anode

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Chinese Chemical Letters 2024年第6期35卷 26-37页

作者： Jiale Zheng Mei Chen Huadong Yuan Jianmin Luo yao Wang Jianwei nai Xinyong Tao Yujing Liu College of Materials Science and Engineering Zhejiang University of TechnologyHangzhou 310014China College of Mechanical and Energy Engineering Zhejiang University of Science and TechnologyHangzhou 310014China

Lithium(Li)metal anodes(LMAs)have garnered significant attention as a potential solution for developing high-energy density batteries,given their theoretical specific capacity and redox ***,safety concerns and internal cycling stability issues originated from uncontrollable Li dendrite growth have impeded the practical application of *** the interface between Li metal and electrolyte is a crucial process that offers valuable insights into the characteristics and regularity of primary circular *** illustrate the intrinsic characteristic of Li metal batteries(LMBs)in spatial and temporal,it is imperative to employ electron microscopes to characterize the structural components distribution of Li with atomic *** paper summarizes the progress in the characterization and analysis of the interfaces in LMBs with electron microscopes based on the principles of electron-matter ***,future trends and the potential of electron microscopes are also discussed to advance our understanding of LMBs.

关键词： Li metal anode Electron microscopy Visualization High-resolution Battery

Simulation and reconstruction of particle trajectories in the CEPC drift chamber

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Nuclear Science and Techniques 2024年第8期35卷 9-22页

作者： Meng‑yao Liu Wei‑Dong Li Xing‑Tao Huang yao Zhang Tao lin Ye Yuan Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China Institute of High Energy Physics Beijing 100049China University of Chinese Academy of Sciences Beijing 100049China

The circular electron-positron collider(CEPC)is designed to precisely measure the properties of the Higgs boson,study electroweak interactions at the Z-boson peak,and search for new physics beyond the Standard *** a component of the 4th conceptual CEPC detector,the drift chamber facilitates the measurement of charged *** study implemented a Geant4-based simulation and track reconstruction for the drift *** the simulation,detector construction and response were implemented and added to the CEPC simulation *** development of track reconstruction involves track finding using the combinatorial Kalman filter method and track fitting using the tool of *** the simulated data,the tracking performance was *** results showed that both the reconstruction resolution and tracking efficiency satisfied the requirements of the CEPC experiment.

关键词： CEPC Drift chamber Detector simulation Track reconstruction

Unified Classification and Rejection:A One-versus-all Framework

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Machine Intelligence Research 2024年第5期21卷 870-887页

作者： Zhen Cheng Xu-yao Zhang Cheng-lin Liu State Key Laboratory of Multimodal Artificial Intelligence Systems Institute of AutomationChinese Academy of SciencesBeijing100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing100049China

Classifying patterns of known classes and rejecting ambiguous and novel(also called as out-of-distribution(OOD))inputs are involved in open world pattern *** neural network models usually excel in closed-set classification while perform poorly in rejecting OOD *** tackle this problem,numerous methods have been designed to perform open set recognition(OSR)or OOD rejection/detection *** methods mostly take post-training score transformation or hybrid models to ensure low scores on OOD inputs while separating known *** this paper,we attempt to build a unified framework for building open set classifiers for both classification and OOD *** formulate the open set recognition of K-known-class as a(K+1)-class classification problem with model trained on known-class samples *** decomposing the K-class problem into K one-versus-all(OVA)binary classification tasks and binding some parameters,we show that combining the scores of OVA classifiers can give(K+1)-class posterior probabilities,which enables classification and OOD rejection in a unified *** maintain the closed-set classification accuracy of the OVA trained classifier,we propose a hybrid training strategy combining OVA loss and multi-class cross-entropy *** implement the OVA framework and hybrid training strategy on the recently proposed convolutional prototype network and prototype classifier on vision transformer(ViT)*** on popular OSR and OOD detection datasets demonstrate that the proposed framework,using a single multi-class classifier,yields competitive performance in closed-set classification,OOD detection,and misclassification *** code is available at https://***/zhen-cheng121/CPN_OVA_unified.

关键词： Open set recognition out-of-distribution detection misclassification detection convolutional prototype network oneversus-all Dempster-Shafer theory of evidence

Cell division cyclin 25C knockdown inhibits hepatocellular carcinoma development by inducing endoplasmic reticulum stress

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World Journal of Gastroenterology 2024年第19期30卷 2564-2574页

作者： Yan-Fei Li Fang-Yuan Zheng Xin-Yu Miao Hai-Long Liu yao-yao Zhang nai-Xia Chao Fa-Rong Mo School of Basic Medical Sciences Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Key Laboratory of Biological Molecular Medicine Research(Guangxi Medical University) Education Department of Guangxi Zhuang Autonomous RegionNanning 530021Guangxi Zhuang Autonomous RegionChina Key Laboratory of Human Development and Disease Research(Guangxi Medical University) Education Department of Guangxi Zhuang Autonomous RegionNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Cell division cyclin 25C(CDC25C)is a protein that plays a critical role in the cell cycle,specifically in the transition from the G2 phase to the M *** research has shown that CDC25C could be a potential therapeutic target for cancers,particularly for hepatocellular carcinoma(HCC).However,the specific regulatory mechanisms underlying the role of CDC25C in HCC tumorigenesis and development remain incompletely *** To explore the impact of CDC25C on cell proliferation and apoptosis,as well as its regulatory mechanisms in HCC *** Hepa1-6 and B16 cells were transduced with a lentiviral vector containing shRNA interference sequences(LV-CDC25C shRNA)to knock down ***,a xenograft mouse model was established by subcutaneously injecting transduced Hepa1-6 cells into C57BL/6 mice to assess the effects of CDC25C knockdown on HCC development in *** proliferation and migration were evaluated using a Cell Counting Kit-8 cell proliferation assays and wound healing assays,*** expression of endoplasmic reticulum(ER)stress-related molecules(glucose-regulated protein 78,X-box binding protein-1,and C/EBP homologous protein)was measured in both cells and subcutaneous xenografts using quantitative real-time PCR(qRT-PCR)and western ***,apoptosis was investigated using flow cytometry,qRT-PCR,and western *** CDC25C was stably suppressed in Hepa1-6 and B16 cells through LV-CDC25C shRNA transduction.A xenograft model with CDC25C knockdown was successfully established and that downregulation of CDC25C expression significantly inhibited HCC growth in ***25C knockdown not only inhibited cell proliferation and migration but also significantly increased the ER stress response,ultimately promoting ER stress-induced apoptosis in HCC *** The regulatory mechanism of CDC25C in HCC development may involve the activation of ER stress and the ER stress-induced apoptosis signali

关键词： Cell division cyclin 25C Hepatocellular carcinoma Endoplasmic reticulum stress Proliferation Apoptosis

Research on intelligent search-and-secure technology in accelerator hazardous areas based on machine vision

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Nuclear Science and Techniques 2024年第4期35卷 96-107页

作者： Ying-lin Ma yao Wang Hong-Mei Shi Hui-Jie Zhang School of Traffic and Transportation Beijing Jiaotong UniversityBeijing 100044China School of Mechanical Electronic and Control EngineeringBeijing Jiaotong UniversityBeijing 100044China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

Prompt radiation emitted during accelerator operation poses a significant health risk,necessitating a thorough search and securing of hazardous areas prior to ***,manual sweep methods are ***,the limitations of manual sweeps have become increasingly evident with the implementation of large-scale *** leveraging advancements in machine vision technology,the automatic identification of stranded personnel in controlled areas through camera imagery presents a viable solution for efficient search and *** the criticality of personal safety for stranded individuals,search and security processes must be sufficiently *** ensure comprehensive coverage,180°camera groups were strategically positioned on both sides of the accelerator tunnel to eliminate blind spots within the monitoring *** YOLOV8 network model was modified to enable the detection of small targets,such as hands and feet,as well as larger targets formed by individuals near the ***,the system incorporates a pedestrian recognition model that detects human body parts,and an information fusion strategy is used to integrate the detected head,hands,and feet with the identified pedestrians as a cohesive *** strategy enhanced the capability of the model to identify pedestrians obstructed by equipment,resulting in a notable improvement in the recall ***,recall rates of 0.915 and 0.82were obtained for Datasets 1 and 2,*** there was a slight decrease in accuracy,it aligned with the intended purpose of the search-and-secure software *** tests conducted within an accelerator tunnel demonstrated the effectiveness of this approach in achieving reliable recognition outcomes.

关键词： Search and secure Machine vision Camera Human body parts recognition Particle accelerator Hazardous area

Provably secure attribute-based authenticated encryption with keyword search from ideal lattices

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Science China(Information Sciences) 2024年第1期67卷 308-309页

作者： Lisha yao lin HOU Jian WENG Feixiang ZHAO College of Cyber Security Jinan University

A public-key authenticated encryption with keyword search(PAEKS)[1, 2] system overcomes the problem of an inside adversary forging searchable ciphertexts and guessing the keyword information from the given token. This system allows the sender to encrypt and authenticate a ***, traditional PAEKS schemes require the sender to specify the intended receiver in advance, losing much flexibility.

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Sexual Dimorphism and Female Reproductive Characteristics in the Hainan Water Skink(Tropidophorus hainanus)from Hainan,South China

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Asian Herpetological Research 2024年第1期15卷 49-58页

作者： Yu DU Xiaming ZHU Chixian lin Yuntao yao Xiang JI Hainan Key Laboratory for Herpetological Research College of Fisheries and Life SciencesHainan Tropical Ocean UniversitySanya 572022HainanChina Zhejiang Provincial Key Laboratory for Water Environment and Marine Biological Resources Protection College of Life and Environmental SciencesWenzhou UniversityWenzhou 325035ZhejiangChina Institute for Eco-environmental Research of Sanyang Wetland Wenzhou UniversityWenzhou 325014ZhejiangChina

We studied sexual dimorphism in body size and shape and female reproductive characteristics in the Hainan Water Skink(Tropidophorus hainanus)from Hainan,South *** our sample the largest female and male were 61.1 and 55.2 mm snout-vent length(SVL),*** mean SVL was larger in adult females(52.0 mm)than in adult males(48.3 mm).Juveniles were sexually dimorphic in head length but not in other examined morphological *** males were longer in head length and shorter in abdomen length and fore-limb length than adult females of the same *** shifts in sexual dimorphism in body shape were evident,as revealed by the fact that morphological differences between the sexes were more pronounced in adults than in *** produced a single litter of 3–6 offspring per season from early August to early *** size,litter mass and offspring(neonate)mass were positively related to female *** mass was independent of relative *** the above findings we draw three main ***,females are the larger sex in ***,and sexual dimorphism in body shape is more pronounced in adults than in ***,larger female *** produce more and larger offspring and thus heavier litters than smaller ***,the offspring size-number trade-off does is not evident in ***.

关键词： fecundity morphology offspring size-number trade-off reproduction scincidae sexual dimorphism