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World Journal of Gastroenterology 2005年第15期11卷 2357-2359页

作者： Elod Papp Zsuzsanna Keszthelyi nagy karoly kalmar Lajos Papp Csaba Weninger Tamas Tornoczky Endre Kalman Kalman Toth Tamas Habon 1st Department of Medicine Department of Surgery Heart Institute Department of Radiology Department of Pathology

Intracardiac manifestation of hepatocellular carcinoma (HCC) is a rare condition and an uncommon finding even at autopsy. Pulmonary tumor embolism as a presenting feature of HCC has been published only twice previously. In our case report, a 63-year-old man presented with high fever and six episodes of recurrent pneumonias during the last half year. Echocardiography was performed, a solid mass was found in the right atrium. Transesophageal echocardiography proved a tumor mass in the inferior vena cava (IVC) extending into the right atrium, abdominal ultrasound revealed tumor mass in the IVC and a solid tumor in the liver. Combined liver and heart surgery was attempted in order to remove the tumor mass from both the liver and the right atrium. Acute cor pulmonale occurred during tumor removal from the right atrium and the patient expired. In addition to local factors the possibility of embolization should arise in the background of recurrent pneumonia. Occult carcinoma must be included in possible causes of recurrent pulmonary embolism. Searching for primary malignancy should include HCC as frequent cause of hypercoagulability. In case of HCC, echocardiography is suggested because of the possibility of expansion in IVC or right atrium and tumor-embolization.

关键词： Hepatocellular carcinoma Intracardiac penetration Pulmonary embolization

WEAK TYPE INEQUALITY FOR THE MAXIMAL OPERATOR OF WALSH-KACZMARZ-MARCINKIEWICZ MEANS

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Acta Mathematica Scientia 2016年第2期36卷 359-370页

作者： Ushangi GOGINAVA karoly nagy Department of Mechanics and Mathematics Tbilisi State University Chavchavadze str. 1 Tbilisi 0128 Georgia Institute of Mathematics and Computer Sciences College of Nyiregyhdza SSstSi str. 31/B 4400 Nyiregyhdza Hungary

The main aim of this article is to prove that the maximal operator σ^k＊ of the Marcinkiewicz-Fejer means of the two-dimensional Fourier series with respect to Walsh- Kaczmarz system is bounded from the Hardy space H... 详细信息

关键词： Walsh-Kaczmarz system Marcinkiewicz-Fej^r means Maximal operator a.e.convergence weak type inequality

HIV among people who inject drugs in Hungary

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Infectious Diseases of Poverty 2017年第1期6卷 1289-1293页

作者： Andras Ortutay VAnna Gyarmathy Zsuzsa Marjanek karoly nagy Jozsef Racz Istvan Barcs Anaesthesiology and Intensive Care Unit Javorszky Idon HospitalVácHungary Johns Hopkins Bloomberg School of Public Health BaltimoreMDUSA Faculty of General Medicine Institute of Medical MicrobiologySemmelweis UniversityBudapestHungary Institute of Psychology Eotvos Lorand UniversityBudapestHungary Faculty of Health Sciences Department of AddictologySemmelweis UniversityBudapestHungary Faculty of Health Sciences Department of EpidemiologySemmelweis UniversityBudapestHungary

Background:Before 2014(the year of closure of the two largest needle exchange programs in Hungary,which halved the number of available syringes in the country despite increased injecting risk practices)no HIV was reportedly acquired in Hungary among people who inject drugs(PWIDs)who were not also men who had sex with other men(MSM).In 2014,one and in 2015 two non-MSM PWIDs were newly diagnosed with HIV who supposedly became infected in Hungary,and both incident HIV cases in 2015 were diagnosed in the AIDS *** addition,two new(albeit supposedly imported)non-MSM PWID cases were also registered in the first three quarters of 2016,one of which subsequently was diagnosed with and then died of *** the same time,the prevalence of HCV doubled among PWIDs(from 24%to 49%in Hungary and from 34%to 61%in Budapest).Case presentation:The case that we discuss in this paper is a male PWID,who was diagnosed with HIV and AIDS in May of 2015 and then died of AIDS the next *** HIV infection status was detected with delay,and then appeared in the official statistics as an incident PWID HIV case and an incident PWID AIDS case,but not as an incident PWID AIDS *** contact tracing followed,even though it would have been relatively easy considering the *** our knowledge,no HIV post-exposure protocol exists in hospitals,in case of HIV exposure due to an eventual needle-stick ***:Our paper draws attention to recently published HIV and AIDS surveillance data,and shows the failure of the *** sounding the alarm based on three newly detected PWID HIV cases in the past 2 years may be premature,there are definitely serious problems in the HIV detection and tracing system among PWIDs in Hungary.

关键词： People who inject drugs HIV/AIDS Surveillance

What Is the Personal Experience of IBD Patients about Their Anti-TNF-Alpha Therapy?

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Health 2017年第7期9卷 1007-1018页

作者： Agnes Milassin Mariann Rutka Agnes Anna Csontos Pal Miheller karoly Palatka Monika Szucs Zoltan Szepes Anita Balint Renata Bor Anna Fabian Klaudia Farkas Ferenc nagy Tamas Molnar First Department of Medicine University of SzegedSzegedHungary 2^(nd) Department of Medicine Semmelweis UniversityBudapestHungary 2^(nd) Department of Internal Medicine University of DebrecenDebrecenHungary Department of Medical Physics and Informatics University of SzegedSzegedHungary

AIM: To evaluate and compare the patients opinion on the two types of anti- TNF-α therapies in a Hungarian cohort of IBD patients. METHODS: This was a prospective, multicentre, questionnaire-based observational study carried out in three Hungarian tertiary centres. From April to September 2014, an anonymous questionnaire was distributed to patients diagnosed with ulcerative colitis (UC) or Crohn’s disease (CD), who have received infliximab (IFX) and/or adalimumab (ADA). The survey focused on the preferences of the two anti-TNF-α therapies on the basis of the efficacy, the administration routes and the side effects. RESULTS: 292 IBD patients, 216 CD, 75 UC and 1 indeterminate colitis patient completed the questionnaire. The mean duration of biological therapy was 1.7 (1 - 7) years. IFX treated patients noticed improvement of symptoms at 4 - 5 weeks while ADA treated patients noticed at 5 - 6 weeks. There was no difference between the patients’ satisfaction regarding the types of anti-TNF-α therapy if they received both. However, subcutaneous administration was preferred by ADA-treated patients previously receiving IFX (p = 0.007) compared to intravenous route and they did not intend to change the mode of therapy (p = 0.040). 90% of the patients, receiving only IFX or ADA were satisfied with their present therapy. The majority of patients (186/292, 63.7%) would not switch therapy. 63 of 291, 22% of the patients reported to have some concern with biological therapy—the majority (32/63, 50.8%) due to fear from side effects. CONCLUSION: Generally, patients preferred and would not change the present anti-TNF-α therapy, however, subcutaneous administration was preferred among those patients who had have experience with both.

关键词： Patient’s Satisfaction Personal Experience Questionnaire Anti-TNF-Alpha Therapy Patient’s Preference

Large Scale Experiments on the Investigation of the Effect of High Concentrations of Aflatoxin B1 on the Fermentation of Different Wines

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Journal of Agricultural Chemistry and Environment 2014年第2期3卷 41-47页

作者： Cs. Csutorás K. Rácz G. Z. nagy O. Hudák L. Rácz Eger Crown Winehouse Ltd. Kerecsend Hungary Institute of Food Science Egerfood Regional Knowledge Center Eszterhazy Karoly University Eger Hungary

The change of aflatoxin B1 (AFB1) content during must fermentation processes in different white, rosé and red musts was investigated, using selected yeast strains of Saccharomyces cerevisiae as starter cultures. Levels of AFB1 in must and lees were determined by high-performance liquid chromatography (HPLC) combined with diode array detection (DAD). Reductions of the AFB1 content between 77% - 97% were recorded after 90 days must fermentations in the model systems, while the relative adsorption level of AFB1 in lees was around ~0.63 in case of white wines, ~0.41 in case of rosé wines and ~0.23 in case of red wines. The results show that even extremely high AFB1 levels do not affect the fermentation process and the life-circle of yeast strains. The concentration of AFB1 in wine can be controlled by using appropriate yeast strains during the alcoholic fermentation.

关键词： Mycotoxicoses Contamination Decontamination Food Safety HPLC

Notes,outline and divergence times of Basidiomycota

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Fungal Diversity 2019年第6期99卷 105-367页

作者： Mao-Qiang He Rui-Lin Zhao Kevin D.Hyde Dominik Begerow Martin Kemler Andrey Yurkov Eric H.C.McKenzie Olivier Raspe Makoto Kakishima Santiago Sanchez-Ramırez Else C.Vellinga Roy Halling Viktor Papp Ivan V.Zmitrovich Bart Buyck Damien Ertz Nalin N.Wijayawardene Bao-Kai Cui Nathan Schoutteten Xin-Zhan Liu Tai-Hui Li Yi-Jian Yao Xin-Yu Zhu An-Qi Liu Guo-Jie Li Ming-Zhe Zhang Zhi-Lin Ling Bin Cao Vladimir Antonin Teun Boekhout Bianca Denise Barbosa da Silva Eske De Crop Cony Decock Balint Dima Arun Kumar Dutta Jack W.Fell Jozsef Geml Masoomeh Ghobad-Nejhad Admir J.Giachini Tatiana B.Gibertoni Sergio P.Gorjon Danny Haelewaters Shuang-Hui He Brendan P.Hodkinson Egon Horak Tamotsu Hoshino Alfredo Justo Young Woon Lim Nelson Menolli Jr Armin Mesic Jean-Marc Moncalvo Gregory M.Mueller La szlo G.nagy RHenrik Nilsson Machiel Noordeloos Jorinde Nuytinck Takamichi Orihara Cheewangkoon Ratchadawan Mario Rajchenberg Alexandre G.S.Silva-Filho Marcelo Aloisio Sulzbacher Zdenko Tkalcec Ricardo Valenzuela Annemieke Verbeken Alfredo Vizzini Felipe Wartchow Tie-Zheng Wei Michael WeiB Chang-Lin Zhao Paul M.Kirk State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101People’s Republic of China Department of Entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand College of Life Sciences University of Chinese Academy of SciencesHuairou DistrictBeijing 100408People’s Republic of China Ruhr-Universitat Bochum AG GeobotanikND03UniversitatsstraBe 15044801 BochumGermany Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures InhoffenstraBe 7B38124 BrunswickGermany Manaaki Whenua-Landcare Research Private Bag 92170AucklandNew Zealand Research Department Meise Botanic GardenNieuwelaan 381860 MeiseBelgium Service General de l'Enseignement superieur et de la Recherche scientifique Federation Wallonie-BruxellesLavallee 11080 BrusselsBelgium University of Tsukuba TsukubaIbaraki 305-8572Japan Department of Ecology and Evolutionary Biology University of Toronto25 Willcocks St.TorontoON M5S 3B2Canada Berkeley USA Institute of Systematic Botany The New York Botanical GardenBronxNY 10458-5126USA Department of Botany Szent Istvan University1518 BudapestHungary Komarov Botanical Institute Russian Academy of SciencesProfessor Popov st.2Saint PetersburgRussia 197376 Institut pour Systematique Ecologie Biodiversite(ISYEB UMR 7205) Sorbonne universiteMuseum National d’Histoire Naturelle CP 39CNRSDepartement Origines et Evolution12 Rue Buffon75005 ParisFrance Institute of Microbiology Beijing Forestry UniversityBeijing 100083People’s Republic of China Department of Biology Research Group MycologyGhent UniversityK.L.Ledeganckstraat 359000 GhentBelgium State Key Laboratory of Applied Microbiology Southern China Guangdong Provincial Key Laboratory of Microbial Culture Collection and ApplicationGuangdong Institute of MicrobiologyGuangzhou 510070People’s Republic of China Department of Botany Moravian Mu

The Basidiomycota constitutes a major phylum of the kingdom Fungi and is second in species numbers to the *** present work provides an overview of all validly published,currently used basidiomycete genera to date in a single *** outline of all genera of Basidiomycota is provided,which includes 1928 currently used genera names,with 1263 synonyms,which are distributed in 241 families,68 orders,18 classes and four *** provide brief notes for each accepted genus including information on classification,number of accepted species,type species,life mode,habitat,distribution,and sequence ***,three phylogenetic analyses with combined LSU,SSU,5.8s,rpb1,rpb2,and ef1 datasets for the subphyla Agaricomycotina,Pucciniomycotina and Ustilaginomycotina are conducted,*** time estimates are provided to the family level with 632 species from 62 orders,168 families and 605 *** study indicates that the divergence times of the subphyla in Basidiomycota are 406-430 Mya,classes are 211-383 Mya,and orders are 99-323 Mya,which are largely consistent with previous *** this study,all phylogenetically supported families were dated,with the families of Agaricomycotina diverging from 27-178 Mya,Pucciniomycotina from 85-222 Mya,and Ustilaginomycotina from 79-177 *** times as additional criterion in ranking provide additional evidence to resolve taxonomic problems in the Basidiomycota taxonomic system,and also provide a better understanding of their phylogeny and evolution.

关键词： Classification Molecular clock Fungi Systematics Taxonomy