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Open label,interventional,single arm multicentric clinical study to analyze the potency of VELNEZ nasal pack,post-nasal surgery

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第3期10卷 180-186页

作者： Shama Bellad nagula parusharam Vineeta Dhyani Pankaj Bablani Siddharth Pandey Department of ENT Jawaharlal Nehru Medical CollegeBelagaviKarnatakaIndia Department of ENT Mahatma Gandhi Memorial HospitalWarangalTelanganaIndia Department of Pharmacy Practice KLE UniversityBelagaviKarnatakaIndia Datt Mediproducts Pvt.Ltd. New DelhiIndia

Background:Nasal packs are central to nasal ***,these packs function by controlling bleeding,modulating pain and reducing adhesions ***,the major setback of the currently used conventional nasal packs is the unbearable pain the patient undergoes upon removal of these *** overcome this shortcoming a variety of biodegradable packs have *** study was aimed at evaluating the safety,efficacy and tolerability of VELNEZ nasal ***,a patented Datt Mediproducts *** pack,is one of its kind biodegradable composite that fragments within a few days of ***:Eighty patients were included in an open label,interventional,single arm clinical study using clinical endpoints to investigate the safety and efficacy of nasal pack *** patients were questioned using a visual analog scale from discharge day to 28th postoperative day(9 follow-up visits)at regular *** standardized questionnaires for hemorrhage control,relief from postoperative pain,moderate obstruction,and pain were ***:A total of 76 patients were enrolled in the study and 74 patients completed the *** nasal pack played a significant role in controlling hemorrhage and reducing postoperative *** average hemorrhage control time was 7.49±3.90 min with only 34.24%of population complaining of pain on the sixth day of surgery(follow-up 4).Forteen days postsurgery only 10.95%of subject population complained of postoperative *** biodegradable composite has an average fragmentation time of 4.7 days in the nasal *** addition,this study did not observe any postoperative adverse events or serious adverse ***:VELNEZ,a fragmentable nasal pack,is comfortable,safe,and effective against postsurgery bleeding and pain.

关键词： clinical trial registry fragmentable functional endoscopic sinus surgery visual analog scale

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Primary Tuberculosis of Tonsil in a Diabetic Patient—A Case Report

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International Journal of Otolaryngology and Head & Neck Surgery 2015年第3期4卷 190-195页

作者： nagula parusharam Kamreddy Ashok Reddy Lokesh Rao Magar Jadi Lingaiah Department of E.N.T. Kakatiya Medical College MGM Hospital Warangal India Department of Pathology Kakatiya Medical College MGM Hospital Warangal India Department of ENT & HNS Chalmeda Anand Rao Institute of Medical Sciences Karimnagar India

Though Tuberculosis is one of the most common causes of ill health and death worldwide, people with diabetes have 2 - 3 times higher risk of tuberculosis when compared with people without diabetes. Though tuberculosis can affect any part of the body, oral and oropharyngeal tuberculosis is rare, but reported. And it’s association with diabetes mellitus because of the decreased host mechanism, is still rare, but reported. A 50-year-old female diabetic who was on insulin therapy came to OPD of MGM hospital, Kakatiya Medical College, Warangal with complaints of severe pain in throat for the last 6 months. On examination, right tonsil was enlarged with granular surface. Left tonsil and rest of the oropharynx were normal. Examination of chest was normal and there was no evidence of pulmonary tuberculosis. Punch biopsy revealed tuberculosis of tonsil. Isolated cases of primary tuberculosis of tonsil without evidence of pulmonary tuberculosis are rare. Presence of diabetes mellitus makes patients 2 - 3 times more vulnerable for tubercular infection.

关键词： Tonsil Primary Tuberculosis Diabetes Mellitus

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