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Association of Hypomagnesemia in Type 2 Diabetic Patients with and without Peripheral Neuropathy

Journal of Diabetes Mellitus 2018年第2期8卷 27-42页

作者： Anwar Ali jamali Ghulam mustafa jamali Bhojo Mal Tanwani Ameer Ali jamali Yash Tanwani naeem mustafa jamali Department of Medicine Peoples University of Medical and Health Sciences Nawabshah Pakistan Department of Physiology Peoples University of Medical and Health Sciences for Women Nawabshah Department of Paediatrics Medicine Peoples University of Medical and Health Sciences for Women Nawabshah Pakistan Ziauddin Medical University Karachi Pakistan Liaquat University of Medical and Health Sciences Jamshoro Pakistan

Background: Diabetes Mellitus is a wide-ranging metabolic disorder, which constitutes a most important physical condition dilemma in the world. Hypomagnesaemia accelerates the rate of diabetic complications. Objective: To analyze the association of serum magnesium (Mg) in Type 2 Diabetes Mellitus with and without complication of peripheral neuropathy. Design: A cross sectional study. Setting: This research was carried out in medicine department, Peoples Medical College Hospital Nawabshah from May 2016-April 2017. Sample Size: Total 271 patients of both genders with Type 2 DM with and without peripheral neuropathy, each group after fulfilling the selection criteria were included. Material and Methods: After a short-lived consultation, the subjects were categorized for variable analyses like sex, age, Type 2 Diabetes Mellitus with and without peripheral neuropathy, duration of diabetes mellitus and presence of hypomagnesaemia. Clinical examination with monofilament was applied for diagnosis of peripheral neuropathy. Blood samples for magnesium analysis were collected in fasting condition. Results: In 271 diagnosed patients of Type 2 diabetes mellitus, 180 male and 91 were females. Peripheral neuropathy was observed in 136 subjects out of them 94 males and 42 were females. While 135 were without peripheral neuropathy out of them 86 males and 49 were females. Normal magnesium was seen in 119 (43.91%) and low magnesium was present in 152 (56.09%) patients overall. A decreased serum level of magnesium was observed in 56.09% diabetic subjects with peripheral neuropathy and 50% subjects with diabetes without peripheral neuropathy. Conclusion: Frequency of hypomagnesaemia is common in subjects with in Type 2 DM with and without peripheral neuropathy.

关键词： Type 2 Diabetes Mellitus Hypomagnesaemia Peripheral Neuropathy

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