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Effects of tissue-cultured mountain ginseng （Panax ginseng CA Meyer） extract on male patients with erectile dysfunction

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Asian Journal of Andrology 2009年第3期11卷 356-361页

作者： Tae-Hwan Kim Seung Hyun Jeon Eun-Joo Hahn Kee-Yoeup Paek Jong Kwan Park nae young youn Hyung-Lae Lee Department of Urology School of Medicine Kyung Hee University Seoul 134-727 Korea Research Center for the Development of Advanced Horticultural Technology Chungbuk National University Cheongju 361-711 Korea Department of Urology Chonbuk National University Medical School Jeonju 561-712 Korea Infertility Clinic Sanbornjeil Women＇s Hospital Kunpo 435-042 Korea

Korean ginseng and mountain ginseng （Panax ginseng CA Meyer） are important traditional herbal plants whose ginsenosides are generally accepted as serving to improve sexual functions, such as penile erection. We investigated the effects of tissue-cultured mountain ginseng extract （TMGE） on male patients with erectile dysfunction （ED）. A double-blind, placebo-controlled study was conducted with 143 patients experiencing ED. Over the course of 8 weeks, one group took 1 000 mg of TMGE twice a day, and the other group took 1 000 mg of placebo twice a day. The effects of the TMGE and the placebo were analyzed using the Korean version of the International Index of Erectile Function （IIEF） questionnaire. A total of 86 patients completed 8 weeks of treatment. The scores on the five domains of the IIEF after medication were significantly higher than the baseline scores in the group treated with TMGE （P 〈 0.05）, whereas no significant improvement was observed in the placebo group （P 〉 0.05）. Erectile function and overall satisfaction scores after medication were significantly higher in the TMGE group than in the placebo group （P 〈 0.05）. Erectile function of patients in the TMGE-treated group significantly improved, suggesting that TMGE could be utilized for improving erectile function in male patients.

关键词： erectile dysfunction Panax ginseng tissue-cultured mountain ginseng extract

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A New Encryption Mechanism Supporting the Update of Encrypted Data for Secure and Efficient Collaboration in the Cloud Environment

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 813-834页

作者： Chanhyeong Cho Byeori Kim Haehyun Cho Taek-young youn Department of Cyber Security Dankook UniversityYongin16890Republic of Korea Department of Software Soongsil UniversitySeoul07027Republic of Korea

With the rise of remote collaboration,the demand for advanced storage and collaboration tools has rapidly ***,traditional collaboration tools primarily rely on access control,leaving data stored on cloud servers vulnerable due to insufficient *** paper introduces a novel mechanism that encrypts data in‘bundle’units,designed to meet the dual requirements of efficiency and security for frequently updated collaborative *** bundle includes updated information,allowing only the updated portions to be reencrypted when changes *** encryption method proposed in this paper addresses the inefficiencies of traditional encryption modes,such as Cipher Block Chaining(CBC)and Counter(CTR),which require decrypting and re-encrypting the entire dataset whenever updates *** proposed method leverages update-specific information embedded within data bundles and metadata that maps the relationship between these bundles and the plaintext *** utilizing this information,the method accurately identifies the modified portions and applies algorithms to selectively re-encrypt only those *** approach significantly enhances the efficiency of data updates while maintaining high performance,particularly in large-scale data *** validate this approach,we conducted experiments measuring execution time as both the size of the modified data and the total dataset size *** show that the proposed method significantly outperforms CBC and CTR modes in execution speed,with greater performance gains as data size ***,our security evaluation confirms that this method provides robust protection against both passive and active attacks.

关键词： Cloud collaboration mode of operation data update efficiency

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Usefulness of the acromioclavicular joint cross-sectional area as a diagnostic image parameter of acromioclavicular osteoarthritis

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World Journal of Clinical Cases 2022年第7期10卷 2087-2094页

作者： young Joo Jee youn Moon Jung youn Han Yun-Sic Bang Keum nae Kang young Su Lim young-SoonChoi young-Uk Kim Department of Anesthesiology and Pain Medicine CHA Ilsan Medical CenterSchool of MedicineCHA UniversityIlsanGyeonggi-do 10414South Korea Department of Anesthesiology and Pain Medicine Seoul National University Hospital College of MedicineSeoul 03080South Korea Department of Anesthesiology and Pain Medicine CHA Bundang Medical CenterSchool of MedicineSeongnamGyeonggi-do 13496South Korea Department of Anesthesiology and Pain Medicine National Police HospitalSeoul 05715South Korea Department of Anesthesiology and Pain Medicine Catholic Kwandong UniversityCollege of MedicineInternational St.Mary’s HospitalIncheon 22711South Korea

BACKGROUND Acromioclavicular joint(ACJ)space narrowing has been considered to be an important diagnostic image parameter of ACJ osteoarthritis(ACJO).However,the morphology of the ACJ space is irregular because of osteophyte formation,subchondral irregularity,capsular distention,sclerosis,and ***,we created the ACJ cross-sectional area(ACJCSA)as a new diagnostic image parameter to assess the irregular morphologic changes of the *** To hypothesize that the ACJCSA is a new diagnostic image parameter for *** ACJ samples were obtained from 35 patients with ACJO and 30 healthy individuals who underwent shoulder magnetic resonance(S-MR)imaging that revealed no evidence of *** coronal,T2-weighted,fat-suppressed SMR images were acquired at the ACJ level from the two *** measured the ACJCSA and the ACJ space width(ACJSW)at the ACJ on the S-MR images using our imaging analysis *** ACJCSA was measured as the cross-sectional area of the *** ACJSW was measured as the narrowest point between the acromion and the *** The average ACJCSA was 39.88±10.60 mm;in the normal group and 18.80±5.13 mm;in the ACJO *** mean ACJSW was 3.51±0.58 mm in the normal group and 2.02±0.48 mm in the ACJO *** individuals had significantly lower ACJCSA and ACJSW than the healthy *** operating characteristic curve analyses demonstrated that the most suitable ACJCSA cutoff score was 26.14 mm^(2),with 91.4%sensitivity and 90.0%*** The optimal ACJSW cutoff score was 2.37 mm,with 88.6%sensitivity and 96.7%*** though both the ACJCSA and ACJSW were significantly associated with ACJO,the ACJCSA was a more sensitive diagnostic image parameter.

关键词： Acromioclavicular joint Osteoarthritis Cross-sectional area Diagnosis

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Bi-directional and concurrent proof of ownership for stronger storage services with de-duplication

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Science China(Information Sciences) 2018年第3期61卷 84-94页

作者： Taek-young youn Ku-young CHANG Electronics and Telecommunications Research Institute

In storage service, data de-duplication is a specialized technique for eliminating duplicate copies of repeating data in storage. Especially, client-side de-duplication has more merits than server-side deduplication since they can improve both the space efficiency and the communication bandwidth. For secure client-side de-duplication, we need a way to prove the ownership of a file to be stored. In the upload step,the server should verify the ownership of a client to give the right of the file without uploading it. On the contrary, the client also want to verify the retrievability for the file since he will delete it from his storage after protocol execution. Existing proof of ownership techniques have been designed for server's need. In this paper, we first point out that we need the second property in client's view point, and give a very simple and practical solution which can support the server and the client to prove that they have the same file. We first describe a generic strategy which can help us to construction a bi-directional and concurrent proof of ownership technique from an ordinary proof of ownership technique, and then give an efficient hash-based scheme with security proof in the random oracle model.

关键词： cloud storage secure de-duplication data out-source proof of ownership bi-directional and concurrent proof

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Development of a Powder Extruder System for Dual-pore Tissue-engineering Scaffold Fabrication

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Journal of Bionic Engineering 2019年第4期16卷 686-695页

作者： nae-Un Kang Myoung Wha Hong young Yul Kim young-Sam Cho Seung-Jae Lee Department of Mechanical Design Engineering College of EngineeringWonkwang University460 Iksandae-roIks an Jeonbuk570-749Republic of Korea Department of Orthopedics Daejeon StMary's HospitalCatholic University of Korea64Daeheung-i Jung-guDaejeon301-723Republic of Korea

In this study,we developed a powder extruder system that can extrude and deposit powder mixtures to overcome the reported limitations of conventional dualpore scaffold manufacturing *** evaluate the extrusion and deposition capability of the powder extruder system,3D tissue-engineering scaffolds with dual-pore characteristics were fabricated with a PCL/PEO/NaCl(polycaprolactone/polyethylene oxide/sodium chloride)powder *** addition,to evaluate the fabricated scaffolds,their compressive modulus,morphology,and in-vitro cell activity were ***,it was confirmed that the proposed powder extruder system can fabricate dual-pore scaffolds with well-interconnected pores as well as arbitrary 3D shapes shown by the fabrication of a 3D femur-shape scaffold similar to the femur *** results of the cell proliferation and Cell Counting Kit-8(CCK-8)assays,DNA content analysis and viability assays confirm that the dual-pore scaffold fabricated by the powder extruder system improves cell attachment,proliferation,and viability.

关键词： dual-pore scaffold powder extruder system polycaprolactone 3D tissue-engineering scaffold

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Mode of Operation for Modification, Insertion, and Deletion of Encrypted Data

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Computers, Materials & Continua 2022年第10期73卷 151-164页

作者： Taek-young youn Nam-Su Jho Dankook University YonginGyeonggi16890Korea Electronics and Telecommunications Research Institute Daejeon34129Korea

Due to the development of 5G communication,many aspects of information technology(IT)services are *** the development of communication technologies such as 5G,it has become possible to provide IT services that were difficult to provide in the *** of the services made possible through this change is cloud-based *** order to support secure collaboration over cloud,encryption technology to securely manage dynamic data is ***,since the existing encryption technology is not suitable for encryption of dynamic data,a new technology that can provide encryption for dynamic data is required for secure cloudbased *** this paper,we propose a new encryption technology to support secure collaboration for dynamic data in the ***,we propose an encryption operation mode which can support data updates such as modification,addition,and deletion of encrypted data in an encrypted *** support the dynamic update of encrypted data,we invent a new mode of operation technique named linked-block cipher(LBC).Basic idea of our work is to use an updatable random value so-called link to link two encrypted *** to the use of updatable random link values,we can modify,insert,and delete an encrypted data without decrypt it.

关键词： Data encryption cloud-based collaboration dynamic data update

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Signcryption with fast online signing and short signcryptext for secure and private mobile communication

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Science China(Information Sciences) 2012年第11期55卷 2530-2541页

作者： youn Taek-young HONG Dowon Electronics and Telecommunications Research Institute(ETRI) Department of Applied Mathematics Kongju National University

Signcryption scheme is one of the useful tools for secure communication where authenticity and confidentiality are simultaneously ***,mobile devices are more and more widely used for communication,and thus it is desirable to design a scheme suitable to mobile *** this paper,we propose a signcryption scheme which is efficient enough to be implemented on mobile *** our scheme,we need only one multiplication in an online phase,and thus a signcryptor can generate a signcryptext very efficiently in the online ***,the size of signcryptext is very short compared with exsiting schemes,and thus our scheme is very efficient in terms of communication *** security of our signcryption scheme is proven in the random oracle model.

关键词： security privacy signcryption short signature

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Development of genome engineering technologies in cattle: from random to specific

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Journal of Animal Science and Biotechnology 2018年第2期9卷 285-293页

作者： Soo-young Yum Ki-young youn Woo-Jae Choi Goo Jang Department of Veterinary Clinical Science College of Veterinary Medicine and the Research Institute of Veterinary Science Seoul National University Farm Animal Clinical Training and Research Center Institute of Green Bio Science Technology Seoul National University Emergence Center for Food-Medicine Personalized Therapy System Advanced Institutes of Convergence Technology Seoul National University College of Veterinary Medicine Seoul National University

The production of transgenic farm animals(e.g., cattle) via genome engineering for the gain or loss of gene functions is an important undertaking. In the initial stages of genome engineering, DNA micro-injection into one-cell stage embryos(zygotes) followed by embryo transfer into a recipient was performed because of the ease of the ***, as this approach resulted in severe mosaicism and has a low efficiency, it is not typically employed in the cattle as priority, unlike in mice. To overcome the above issue with micro-injection in cattle, somatic cell nuclear transfer(SCNT) was introduced and successfully used to produce cloned livestock. The application of SCNT for the production of transgenic livestock represents a significant advancement, but its development speed is relatively slow because of abnormal reprogramming and low gene targeting efficiency. Recent genome editing technologies(e.g.,ZFN, TALEN, and CRISPR-Cas9) have been rapidly adapted for applications in cattle and great results have been achieved in several fields such as disease models and bioreactors. In the future, genome engineering technologies wil accelerate our understanding of genetic traits in bovine and wil be readily adapted for bio-medical applications in cattle.

关键词： Cattle CRISPR-Cas9 Genome engineering technologies Transgenesis Transposon

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Dendrite Spacing Selection during Directional Solidification of Pivalic Acid-Ethanol System

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Journal of Materials Science & Technology 2008年第3期24卷 340-342页

作者： Myung-Jin Suk young-Min Park youn-Che Kim Department of Materials and-Metallurgical Engineering Kangwon National University

Unidirectional solidification of pivalic acid （PVA）-ethanol （Eth） mixture was performed to examine whether an allowable range of primary dendrite spacing definitely exists at a given growth velocity and how the range is history-dependent. PVA-0.59 wt pct Eth was unidirectionally solidified in the range of growth velocity 0.5-64 μm/s at the temperature gradient of 2.3 K/ram. Sequential change in growth velocity was imposed to determine the upper and lower limits for the allowable range of stable spacing. An allowable range of the steady state primary spacing was observed at a given growth velocity, and the extent of the range seems to be dependent on the degree to which step-increase or step-decrease in growth velocity is accomplished. As the degree of sequential change in growth velocity increases, the history-dependence of the selection for the primary dendrite spacing tends to disappear.

关键词： Dendrite spacing History-dependent Spacing selection Pivalic acid-ethanol

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Practical Privacy-Preserving ROI Encryption System for Surveillance Videos Supporting Selective Decryption

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Computer Modeling in Engineering & Sciences 2024年第12期141卷 1911-1931页

作者： Chan Hyeong Cho Hyun Min Song Taek-young youn Department of Cyber Security Dankook UniversityYonginGyeonggi-Do16890Republic of Korea

With the advancement of video recording devices and network infrastructure,we use surveillance cameras to protect our valuable *** paper proposes a novel system for encrypting personal information within recorded surveillance videos to enhance efficiency and *** proposed method leverages Dlib’s CNN-based facial recognition technology to identify Regions of Interest(ROIs)within the video,linking these ROIs to generate unique *** IDs are then combined with a master key to create entity-specific keys,which are used to encrypt the ROIs within the *** system supports selective decryption,effectively protecting personal information using surveillance ***,the system overcomes the limitations of existing ROI recognition technologies by predicting unrecognized frames through *** research validates the proposed technology through experimental evaluations of execution time and post-processing techniques,ensuring comprehensive personal information *** for setting the thresholds used in this process are also *** the proposed method could serve as an effective solution to security vulnerabilities that traditional approaches fail to address.

关键词： Privacy de-identification selective decryption surveillance video

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