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Removal of endocrine disrupting chemicals from water through urethane functionalization of microfiltration membranes via electron beam irradiation

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Frontiers of Environmental Science & Engineering 2024年第4期18卷 61-74页

作者： Zahra Niavarani Daniel Breite Muhammad Yasir Vladimir Sedlarik Andrea Prager nadja Schönherr Bernd Abel Roger Gläser Agnes Schulze Leibniz Institute of Surface Engineering eV.(IOM) Permoserstrasse 1504318 LeipzigGermany Centre of Polymer Systems University InstituteTomas Bata University in ZlinTrida Tomase Bati 567876001 ZlinCzech Republic Institute of Chemical Technology Leipzig UniversityLinnestrasse 304103 LeipzigGermany

Polyethersulphone(PES)membranes modified with urethane functional groups were prepared through an interfacial reaction using electron beam *** removal of eight endocrine disrupting chemicals(EDCs)was studied using both pristine and functionalized PES *** prepared membranes underwent characterization using several techniques,including attenuated total reflectance-Fourier transform infrared(ATR-FTIR)spectroscopy,scanning electron microscopy,contact angle analysis,and measurements of pure water ***,dynamic adsorption experiments were conducted to evaluate the adsorption mechanism of the prepared membrane toward the eight *** urethane functionalized membranes were hydrophilic(52°contact angle)and maintained a high permeate flux(26000 L/h m^(2) bar)throughout the filtration *** adsorption results demonstrated that the introduction of urethane functional groups on the membranes significantly enhanced the removal efficiency of 17β-estradiol,estriol,bisphenol A,estrone,ethinylestradiol,and *** adsorption loading of 17β-estradiol on the functionalized PES membrane was 6.7±0.7 mg/m^(2),exhibiting a 5-fold increase compared to the unmodified PES *** membranes were successfully regenerated and reused for three adsorption cycles without experiencing any loss of adsorption capacity.

关键词： Surface functionalization Electron beam irradiation Microfiltration Endocrine disrupting chemicals

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豪华酒店深入中国市场

国际商业技术 2011年第3期 75-75页

作者： nadja brandt[美]

在中国的一线大城市，豪华酒店的市场已接近饱和，因此，越来越多的豪华连锁酒店集团将目光投向了一些较为偏远的地区。2010年11月，西藏自治区的首府拉萨，迎来了首家国际豪华酒店——拉萨瑞吉度假酒店（***）。

关键词：中国市场豪华酒店 2010年西藏自治区酒店集团度假酒店大城市拉萨

Enhanced diagnostic workup increases pathological findings in patients with acute ischaemic stroke:results of the prospective HEBRAS study

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Stroke & Vascular Neurology 2024年第2期9卷 145-152,I0414-I0425页

作者： Simon Hellwig Thomas Krause Jan F Scheitz Juliane Herm Ulrike Grittner nadja Jauert Jochen B Fiebach Mario Kasner Wolfram Doehner Matthias Endres Rolf Wachter Thomas Elgeti Christian H Nolte Karl Georg Haeusler Department of Neurology with Experimental Neurology Charité-Universitätsmedizin Berlincorporate member of Freie Universität Berlin and Humboldt-Universität zu BerlinBerlinGermany Center for Stroke Research Berlin BerlinGermany Berlin Institute of Health at Charité–Universitätsmedizin Berlin BIH Biomedical Innovation AcademyBerlinGermany Department of Neurology Jüdisches Krankenhaus BerlinBerlinGermany German Center for Cardiovascular Diseases(DZHK) Partner Site BerlinBerlinGermany Institute of Biometry and Clinical Epidemiology Charité-Universitätsmedizin BerlinBerlinGermany BIH Center for Regenerative Therapies(BCRT) Berlin Institute of Health at Charité–Universitätsmedizin BerlinBerlinGermany Department of Cardiology Charité-Universitätsmedizin BerlinBerlinGermany Department of Cardiology Campus Benjamin FranklinCharité-Universitätsmedizin BerlinBerlinGermany German Center for Neurodegenerative Diseases(DZNE) Partner Site BerlinBerlinGermany Department of Cardiology University Hospital LeipzigLeipzigGermany Department of Radiology Charité-Universitätsmedizin BerlinBerlinGermany Department of Neurology University Hospital WürzburgWürzburgGermany

Background Stroke aetiology remains cryptogenic in a relevant proportion of patients with acute ischaemic stroke(AIS).We assessed whether enhanced diagnostic workup after AIS yields a higher rate of prespecified pathological findings compared with routine diagnostic care *** Hospitalised patients with AIS were prospectively enrolled in the investigator-initiated observational HEart and BRain Interfaces in Acute Ischaemic Stroke(HEBRAS)study at the Charité,Berlin,*** with AIS without known atrial fibrillation(AF)underwent cardiovascular MR imaging(CMR),MR-angiography of the aortic arch and prolonged Holter-ECG monitoring on top of routine diagnostic *** Among 356 patients with AIS(mean age 66 years,37.6%female),enhanced workup yielded a higher rate of prespecified pathological findings compared with routine care(17.7%vs 5.3%;p<0.001).Consequently,fewer patients were classified as cryptogenic after enhanced diagnostic workup(38.5%vs 45.5%,p<0.001).Routine care included echocardiography in 228(64.0%)*** was successfully performed in 292(82.0%)patients and revealed more often a prespecified pathological finding compared with routine echocardiography(16.1%vs 5.3%).Furthermore,study-related ECG monitoring(median duration 162 hours(IQR 98–210))detected AF in 16(4.5%)patients,while routine monitoring(median duration 51 hours(IQR 34–74))detected AF in seven(2.0%)*** Enhanced diagnostic workup revealed a higher rate of prespecified pathological findings in patients with AIS compared with routine diagnostic care and significantly reduced the proportion of patients with cryptogenic *** registration number NCT02142413.

关键词： routine patients prospective

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涵盖所有物流过程的管理软件

现代制造 2024年第3期 46-47页

作者： nadja Müller 不详

当一家中型物流运输企业为某用户项目引入了物流管理软件之后,将会在自身所有的企业管理运营中使用这样的软件工具。这时它不仅能与企业的SAP管理系统相互连接,还可以实现物流批次的管理。

关键词：物流过程管理运营物流运输企业软件工具管理系统管理软件项目引入

Aging impairs the osteocytic regulation of collagen integrity and bone quality

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Bone Research 2024年第1期12卷 78-94页

作者： Charles A.Schurman Serra Kaya Neha Dole nadja M.Maldonado Luna Natalia Castillo Ryan Potter Jacob P.Rose Joanna Bons Christina D.King Jordan B.Burton Birgit Schilling Simon Melov Simon Tang Eric Schaible Tamara Alliston Department of Orthopaedic Surgery University of CaliforniaSan FranciscoCA 94143USA UC Berkeley/UCSF Graduate Program in Bioengineering San FranciscoCA 94143USA Buck Institute for Research on Aging NovatoCA 94945USA Washington University in St Louis Department of OrthopedicsSt.LouisMO 63130USA Advanced Light Source Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA

Poor bone quality is a major factor in skeletal fragility in elderly *** molecular mechanisms that establish and maintain bone quality,independent of bone mass,are unknown but are thought to be primarily determined by *** hypothesize that the age-related decline in bone quality results from the suppression of osteocyte perilacunar/canalicular remodeling(PLR),which maintains bone material *** examined bones from young and aged mice with osteocyte-intrinsic repression of TGFβsignaling(TβRII^(ocy−/−))that suppresses *** control aged bone displayed decreased TGFβsignaling and PLR,but aging did not worsen the existing PLR suppression in male TβRII^(ocy−/−)*** relationship impacted the behavior of collagen material at the nanoscale and tissue scale in macromechanical *** effects of age on bone mass,density,and mineral material behavior were independent of osteocytic TGFβ.We determined that the decline in bone quality with age arises from the loss of osteocyte function and the loss of TGFβ-dependent maintenance of collagen integrity.

关键词： maintain primarily integrity

Modelling of dust emissions induced by flow over stockpiles and through packed beds

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Particuology 2021年第6期19卷 55-63页

作者： Daniel Schulz nadja Schwindt Eberhard Schmidt Harald Kruggel-Emden Technische Universitat Berlin Chair of Mechanical Process Engineering and Solids ProcessingEmst-Reuter-Platz 1D-10587 BerlinGermany University of Wuppertal Institute of Particle TechnologyRainer-Gruenter-StrGeb.FFD-42119 WuppertalGermany

Dust emissions during storage of non-moving bulk materials are studied with a numerical *** model relies on a contact-model-free Discrete Element Method(DEM)to model the bulk particle-fluid interaction and the dust removal coupled with Computational Fluid Dynamics(CFD)to model the gas and the dust phase in a multiphase ***,two storage scenarios are considered:a flown through packed bed and a flown over *** the first,the performed simulations reveal that the dust discharge can be correlated with the passing fluid pressure *** the second,a parameter study of factors influencing the dust emissions is *** parameters discussed are the stockpile size,the gas velocity,the slope angle,the particle diameter and the shape of the stockpile,taking into account conical and truncated conical *** release correlations are obtained for both scenarios,which reflect very well the obtained numerical results.

关键词： Computational Fluid Dynamics(CFD) Discrete Element Method(DEM) Dust release correlations Stockpile emissions Packed bed emissions

Functional food additives/ingredients production by engineered Corynebacterium glutamicum

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Systems Microbiology and Biomanufacturing 2023年第1期3卷 110-121页

作者： Katarina Cankar nadja A.Henke Volker F.Wendisch Wageningen Plant Research Wageningen University&Research6708PB WageningenThe Netherlands Genetics of Prokaryotes Center for BiotechnologyBielefeld UniversityBielefeldGermany

Corynebacterium glutamicum is a microbial production host established in the industry 60 years *** is mainly used for production of feed and food amino *** *** strain development has been cutting edge since its discovery,it has been engineered for production of a plethora of valuable *** review will focus on recent developments of *** strain engineering for biotransformation and fermentation processes towards flavor and fragrance molecules as well as pigments and sweeteners.

关键词： Corynebacterium glutamicum Flavors Fragrances Pigments Sweeteners

Consensus views on competencies and teaching methods for an interprofessional curriculum on complementary and integrative medicine:A Delphi study

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Journal of Integrative Medicine 2021年第3期19卷 282-290页

作者： Angelika Homberg Katja Krug nadja Klafke Katharina Glassen Cornelia Mahler Svetla Loukanova Department of General Practice and Health Services Research University Hospital HeidelbergHeidelberg69120 HeidelbergGermany Department of Nursing Science University Hospital Tübingen72076 TubingenGermany

Objective:A collaborative team is necessary to help patients achieve their healthcare goals using complementary *** present,healthcare professionals do not feel sufficiently qualified to provide this *** study sought to identify competencies and teaching methods for interprofessional training on complementary and integrative medicine at medical ***:Sixty-five German-speaking experts with various professional backgrounds were invited to take part in a three-round Delphi *** the first round,predefined competencies were assessed on a seven-point Likert scale,and participants were invited to propose additional competencies that would be evaluated in the subsequent *** competencies were ranked based on the participant assessments and were assigned to four relevance *** the second and third rounds,suitable teaching methods were identified using free-text fields and multiple-choice *** a final workshop,participants synthesized the outcomes of the previous sessions and derived key competencies that would be a benefit to undergraduate interprofessional training in complementary and integrative medicine at medical ***:The three rounds plus final worksop were attended by 50,40,36 and 11 *** competencies that these experts determined to be highly relevant to teaching complementary and integrative medicine emphasized,in particular,the respectful treatment of patients and the importance of taking a medical *** these highly relevant competencies,three key targets were agreed upon in the final workshop:students are able to 1)classify and assess complementary medical terms and methods;2)work collaboratively and integrate patients into the interprofessional team;3)involve patients and their relatives respectfully and empathetically in all healthcare *** achieve these competency goals,the following teaching methods were highlighted:students discuss therapy options based on authentic patient c

关键词： Undergraduate education Interprofessional education Complementary medicine Delphi study Curriculum Competency