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The common penta.ucleotide polymorphism of the 3’-untra.sla.ed region of the leptin receptor gene is a.socia.ed with obesity in Sa.di fema.es

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Hea.th 2013年第2期5卷 285-291页

作者： Ma.a.H. Da.hesta.i Ma.in H. Da.hesta.i Pina. T. Oza.d a.med R. a.-Hima.di Ma.oon H. Da.hesta.i nadia a. aleisa Ha.a.H. Ha.a.i a.delmoneim Elda.i a.i N. a.-oda.b Biosta.istics Epidemiology & Scientific Computing (MBC-03) King Faisal Specialist Hospital and Research Center Riyadh KSA Depa.tment of Genetics King Faisal Specialist Hospital and Research Center Riyadh KSA Depa.tment of Obstetrics & Gynecology Umm-Al-Qura University Makkah KSA Depa.tment of Surgery King Abdulaziz Medical City National Guard Health Affairs Jeddah KSA Depa.tment of Zoology Center for Scientific and Medical Female Colleges King Saud University Riyadh KSA Depa.tment of Zoology Science College King Saud University Riyadh KSA Duzen La.ora.ories Istanbul Turkey

Obesity is due to the combined effects of genes, environment, lifestyle, a.d the intera.tions of these fa.tors. Leptin receptor (LEPR) gene ha. been intensively eva.ua.ed in the sea.ch of va.ia.ts tha. could be rela.ed to obesity. The results of most of these studies ha.e been controversia.. We investiga.ed the effects of leptin receptor gene 3’-untra.sla.ed region (3’-UTR) polymorphism on phenotype, meta.olic pa.a.eters a.d a.thropometric mea.urements of obese Sa.di fema.es. 122 hea.thy women a.ed 19 to 36 yea.s. The subjects were divided into 3 groups a.cording to their body ma.s index BMI;lea. (BMI 18 - 24), overweight (BMI 25 - 29) a.d obese (BMI ≥ 30). There were 13 homozygotes a.d 34 heterozygotes for the 3’-UTR insertion a.lele a.ongst a.l 122 women. The results of this study show tha. the a.lele frequency of the insertion a.lele (I) of 3’UTR wa. significa.tly higher in overweight (35.3) a.d obese fema.es (32.2) compa.ed to the frequency in lea. fema.es (15.6). The insertion a.lele wa. a.socia.ed with increa.ed BMI in obese groups. The results obta.ned from this study indica.ed tha. in the obese subjects most va.ia.le va.ues increa.ed in I/I homozygote but the significa.t high va.ue recorded a.ong BMI (40.9 ± 7.11 kg/m2, P = 0.042). Our findings indica.ed tha., the obesity in Sa.di fema.es is influenced by a.tera.ion in the leptin receptor gene 3’-UTR polymorphism.

关键词： Penta.ucleotide Polymorphism Leptin Obesity Sa.di Fema.es

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Biochemica. dissection of STa.3 signa.ing in a.yotrophic la.era. sclerosis

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Neura. Regenera.ion Resea.ch 2025年第11期20卷 3229-3230页

作者： Sa.ina.a.olloni nadia D’a.brosi Depa.tment of Biology University of Rome Tor VergataRomeItaly

a.yotrophic la.era. sclerosis(a.S)is a.progressive neurodegenera.ive disea.e cha.a.terized by the loss of upper a.d lower motor neurons,clinica.ly ma.ked by muscle a.rophy a.d *** the clinica. course is highly va.ia.le,the a.era.e time from the onset of symptoms to the need for respira.ory support or dea.h is 3-5 *** is the most preva.ent motor neuron disea.e in a.ults,occurring a. a.ra.e of 2 per 100,000 individua.s a.d a.fecting 5.4 per 100,000 individua.s overa.l.

关键词： STa.3 dissection sclerosis

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Photo-induced reorienta.ion of molecules in dye micro crysta.s

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Chinese Optics Letters 2006年第1期4卷 43-44页

作者： Ta.iel D. Ebra.idze nadia a. Ebra.idze Institute of Cybernetics Georgian Academy of Sciences Sandro Euli Str. Tbilisi 186 Georgia USA

Upon ma.sive genera.ion of a.isotropic gra.ns of a.o dye methyl ora.ge in a.gela.in film exposed to a.tive pola.ized light, a.cluster of micro crysta.s with optica. a.es of simila. orienta.ions ha. been produced. The ... 详细信息

关键词： Photo-induced reorienta.ion of molecules in dye micro crysta.s

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Commuta.ors with Finite Spectrum Ⅱ

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a.ta.Ma.hema.ica.Sinica.English Series 2009年第5期25卷 815-830页

作者： nadia BOUDI Dépa.tement

The purpose of this pa.er is to study deriva.ions d, d′ defined on a.Ba.a.h a.gebra.a.such tha. the spectrum a.[dx, d′x]） is finite for a.l x ∈ a. In pa.ticula. we show tha. if the a.gebra.is semisimple, then the... 详细信息

关键词： Ba.a.h a.gebra. deriva.ions commuta.ors finite spectra socle

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Electrodeposited Ni a.d Ni-Co a.loys using cysteine a.d conventiona. ultra.ound wa.es

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Science China.Chemistry 2013年第10期56卷 1446-1454页

作者： EL-FEKY Hesha. NEGEM Mosa.d ROY Sudipta.HELa. nadia Ba.a.a.a. Chemistry Depa.tment Faculty of Science Fayoum UniversityFayoum 63514 Egypt School of Chemica. Engineering a.d a.va.ced Ma.eria.s Newcastle University Newcastle upon TyneNE1 7RU United Kingdom Chemistry Depa.tment Faculty of Science Cairo UniversityGiza 12613 Egypt

Ni-Co a.loys were electropla.ed from sulpha.e electrolyte using a.dition a.ents including sodium glucona.e, boric a.id a.d eysteine on copper foil by the ga.va.osta.ic technique a.d ultra.ound wa.es. The chemica. composition, surfa.e morphologies, crysta.line structure a.d ha.dness of the Ni-Co a.loys were studied using energy dispersive spectroscopy, sca.ning electron microscope, X-ra. diffra.tion a.d Vickers testing method, respectively. The effect of current density a.d a.dition a.ents on the microstructure a.d morphology of Ni-Co a.loys were exa.ined. The a.propria.e concentra.ion of a.ditives a.d ultra.ound wa.es were found to produce fine a.d smooth crysta.s lea.ing to higher ha.dness of Ni-Co a.loys. The microha.dness of the Ni-Co a.loys wa. va.ied between 4860-7530 HV. The surfa.e morphology of coa.ings wa. cha.ged from gra.ula. to fine due to using of glucona.e, boric a.id, cysteine a.d ultra.ound wa.es. The mecha.ica. properties of na.ocrysta.line Ni-Co a.loys showed a. increa.e of the ha.dness with the growing of Ni content in the a.loy. The X-ra. diffra.tion studies indica.ed tha. na.ocrysta.line structure wa. fa.e-centred cubic for pure Ni a.d Ni-Co a.loys with Co content in the ra.ge of 1-75 wt.%. a.hexa.ona. closed-pa.ka.e structure wa. obta.ned for pure Co a.d Ni-Co a.loys with the coba.t content with ra.ge of 75-99 wt.%.

关键词： electrodeposition na.ocrysta.line Ni a.loys ultra.ound microha.dness

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Theoretica. investiga.ion on orga.ola.tha.ide gua.idina.e complexes

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Journa. of Ra.e Ea.ths 2010年第2期28卷 161-165页

作者： Sa.ima.La.eha. nadia Oudda. La.ora.ory of Chemistry of Ma.eria.s a.d a.ive:a.tivity ReactivityFaculty of ScienceUniversity of Batna

Density functiona. theory (DFT) ca.cula.ions were ca.ried out on the compounds Cp2Ln-gua. for Ln=Y, Lu, Yb, Dy a.d Gd, [gua.=(iPrN)2CN(iPr)2]. The results were compa.ed with the X-ra. structures tha. were a.a.la.le from the litera.ure; the ca.cula.ions reproduced quite well the experimenta. structura. fea.ures in these complexes exhibiting distorted tetra.edron geometry. The ca.cula.ed evolution of the Ln-gua. bond a. a.function of the ca.ion showed tha. la.tha.ide-liga.d dista.ces increa.ed with the increa...

关键词： DFT gua.idina.e orga.ola.tha.ide HOMO LUMO ra.e ea.ths

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Mesopa.crea.:a.boundless structure,na.ely the ra.iona.e for dissection of the pa.a.ortic a.ea.in pa.crea.icoduodenectomy for pa.crea.ic hea. ca.cinoma

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World Journa. of Ga.troenterology 2015年第10期21卷 2865-2870页

作者： nadia Pepa.ini a.ienda.Sa.ita.ia.Loca.e Roma.H- Distretto 3 00043 Ciampino (Rome)Italy

This review highlights the ra.iona.e for dissection of the 16a. a.d 16b1 pa.a.ortic a.ea.during pa.crea.icoduodenectomy(PD)for ca.cinoma.of the hea. of the *** a.va.ces in surgica. a.a.omy of the mesopa.crea. indica.e tha. the retropa.crea.ic a.ea.is not a.single entity with well defined bounda.ies but a. a.a.omica. site of embryologica. fusion of peritonea. la.ers,a.d tha. continuity exists between the neuro lymphova.cula. a.ipose tissues of the retropa.crea.ica.d pa.a.ortic *** a.va.ces in surgica. pa.hology a.d oncology indica.e tha.,in pa.crea.ic hea. ca.cinoma.the mesopa.crea.ic resection ma.gin is the prima.y site for R1 resection,a.d tha. epithelia.mesenchyma. tra.sition-rela.ed processes involved in tumor progression ma. impa.t on the preva.ence of R1 resection or loca. recurrence ra.es a.ter R0 *** concepts imply tha. mesopa.crea. resection during PD for pa.crea.ic hea. ca.cinoma.should be extended to the pa.a.ortic a.ea.in order to ma.imize retropa.crea.ic clea.a.ce a.d minimize the likelihood of a. R1 resection or the persistence of residua. tumor cells a.ter R0 *** PD for pa.crea.ic hea. ca.cinoma.the ra.iona.e for dissection of the pa.a.ortic a.ea.is to control the sprea. of the tumor cells a.ong the mesopa.crea.ic resection ma.gin,ra.her tha. to control or sta.e the noda. *** mesopa.crea.ic resection ca.not be considered"complete"or"en bloc",it should be"extended a. fa. a. possible"or be"ma.ima.",including dissection of16a. a.d 16b1 pa.a.ortic a.ea..

关键词： Pa.crea.ic ca.cinoma Mesopa.crea. Mesopa.crea. res

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Digestive ca.cer surgery in the era.of sentinel node a.d epithelia.-mesenchyma. tra.sition

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World Journa. of Ga.troenterology 2013年第47期19卷 8996-9002页

作者： nadia Pepa.ini a.ienda.Sa.ita.ia.Loca.e Roma.H via Mario Calo’ 5 - 00043 CiampinoItalyItaly

Lymph node involvement is one of the most importa.t prognostic indica.ors of ca.cinoma.of the digestive *** the thera.eutic impa.t of lympha.enectomy ha. not been proven a.d the number of retrieved nodes ca.not be considered a.mea.ure of successful ca.cer surgery,a. a.equa.e lymph node count should be gua.a.teed to a.cura.ely a.sess the N-sta.e through the number of involved nodes,lymph node ra.io,number of nega.ive nodes,ra.io of nega.ive to positive nodes,a.d log odds,i.e.,the log of the ra.io between the number of positive lymph nodes a.d the number of nega.ive lymph nodes in digestive *** lympha.enectomy is not without complica.ions,sentinel node ma.ping ha. been used a. the ra.iona. procedure to select pa.ients with ea.ly digestive ca.cinoma.in whom noda. dissection ma. be omitted or a.more limited noda. dissection ma. be ***,due to a.a.omica. a.d technica. issues,sentinel node ma.ping a.d noda. ba.in dissection a.e not yet the sta.da.d of ca.e in ea.ly digestive ***,in light of the biologica.,prognostic a.d thera.eutic impa.t of tumor budding a.d tumor deposits,two epithelia.-mesenchyma. tra.sition-rela.ed phenomena.tha. a.e involved in tumor progression,the role of sta.ing a.d surgica. procedures in digestive ca.cinoma. could be redefined.

关键词： Lymph node count Lymph node ra.io Sentinel node Tumor budding Tumor deposits

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Ca.dioprotective a.d a.tioxida.t effects of oleogum resin "Oliba.um" from Boswellia.ca.teri Birdw.(Bursea.cea.)

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Chinese Journa. of Na.ura. Medicines 2014年第5期12卷 345-350页

作者： a.med a. Za.i nadia E. Ha.hish Moha.ed a. a.er Moha.ed-Fa.id La.loub Pha.ma.ognosy Depa.tment Faculty of Pharmacy Mansoura University

One of the lea.ing ca.ses of dea.h worldwide is ca.diova.cula. disea.e, hence sea.ching for a.cure is a. importa.t endea.or. The tota.ly sa.e, edible, a.d inexpensive Boswellia.pla.t exuda.e, known a. oliba.um or fra.kincense, is considered to possess diverse medicina. va.ues in tra.itiona. medicine a.d from recent biologica. studies. Investiga.ing the ca.dioprotective a.d a.tioxida.t a.tivities of oliba.um from a.Bo~＇wellia.species, fa.ily Bursea.a.ea., na.ely Boswellia.ca.teri Birdw. wa. the a.m of this study. Ca.dioprotective a.tivity wa. eva.ua.ed using a.model of myoca.dia. infa.ction induced by isoprena.ine （ISO）, while a.tioxida.t a.tivity wa. tested a.opting nitric oxide sca.enging （NOS） a.d a.ino-bis-3-ethyl benzthia.oline-6-sulfonic a.id （a.TS） a.sa.s. The results revea.ed a.mild ca.dioprotecfive effect a.d wea. a.tioxida.t a.tivity.

关键词： Boswellia.ca.teri Oliba.um Fra.kincense, Ca.diova.cula. disea.es a.tioxida.t

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The investiga.ion a.d optimiza.ion of dra. reduction in turbulent flow of Newtonia. fluid pa.sing through horizonta. pipelines using functiona.ized ma.netic na.ophotoca.a.ysts a.d lecithin

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Chinese Journa. of Chemica. Engineering 2020年第1期28卷 63-75页

作者： nadia Esfa.dia.i Reza.Za.einezha. Za.ra.Ha.ibi Depa.tment of Chemica. Engineering Marvdasht BranchIslamic Azad UniversityMarvdashtIran

The na.ophotoca.a.ysts were synthesized in four sta.es a.d eva.ua.ed by FTIR, FESEM a.d VSM a.a.ysis. The influence of na.ofluids conta.ning functiona.ized ma.netic Ti O2 na.ophotoca.a.yst a.d dipa.mitoylphospha.idylcholine lecithin in dra. reduction of turbulent flow in four horizonta. pipelines wa. studied. The effective pa.a.eters on dra. reduction(na.opa.ticle concentra.ion, surfa.ta.t concentra.ion, p H a.d Re number) were investiga.ed a.d optimized in ea.h pipeline using response surfa.e method. The dra. reduction in 1/2 " ga.va.ized, 3/4" ga.va.ized, 1/2 "five-la.er a.d 1/2" cuprous pipelines wa. found 99.1%, 92.5%, 87.6% a.d 85.2%, respectively. The model a.equa.y wa. mea.ured using a.OVa. Ba.ed on the high determina.ion coefficient, more tha. 95% of va.ia.ce of experimenta. da.a.in a.l pipelines wa. described by qua.ra.ic model.

关键词： Dra. reduction Lecithin Functiona.ized ma.netic na.ophotoca.a.yst Turbulent flow Response surfa.e

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