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对阿根廷感染性心内膜炎流行病学、临床和微生物学特征的全国性调查:EIRA-2研究

世界核心医学期刊文摘（心脏病学分册） 2006年第6期2卷 29-29页

作者： f.rreiros E. nacinovich f. Casabé J.H. 黎一兵 EIRA- 2 Investigators Area de Investigacion Y Consejo de Cardiologia Clinica Y Terapeutica Dr. Tiburcio Padilla Sociedad Argentina de Cardiologa Ciudad Autonoma de Buenos Aires Argentina Dr.

Background: This study aimed to determine the epidemiologic, clinical, microbiologic characteristics, and inhospital outcome of.inf.ctive endocarditis(IE) in Argentina and compare the results with those of.the 1992 IE national survey. Methods: A prospective, multicenter study was conducted in 82 hospitals representing 16 of.24 provinces of.Argentina. Patients with diagnosis of.IE according to the Duke criteria were surveyed during an 18- month period. Results: f.om 470 surveyed episodes of.IE, 390 cases were classif.ed as def.nite and 80 as possible IE. The mean age of.the def.nite IE cases was 58.5± 17.3 years; male sex, 70.0% ; and male- f.male ratio, 2.3 ∶ 1. Pathological evidence of.IE was available in 26.2% . There was no previously known heart disease in 35.1% , and the proportion of.prosthetic valve IE was 15.9% . Causative microorganisms were streptococci, 38.3% (Streptococcus viridans 27.0% , Streptococcus bovis 5.2% , others 6.1% ); enterococci, 10.2% ; staphylococci, 36.7% (Staphylococcus aureus 29.8% , coagulase- negative sta- phylococci 6.9% );HACEK group, 6.1% ; f.ngal, 1.4% ; and polymicrobial, 2.0% . Blood culture results were negative in 10.8% . Surgical treatment was perf.rmed in 26.2% , and the overall inhospital mortality was 24.6% . Patients f.om the 2002 survey were older(58.5± 17.3 vs 51.3± 18.7 years, Pf.equently had underlying heart disease(64.9% vs 55.0% , Pf.rheumatic valve disease was signif.cantly less than in the 1992 survey(5.4% vs 13.0% , Pf.le of.IE has changed in Argentina. Currently, patients with IE are older and have a higher f.equency of.underlying heart disease, degenerative valve disease, and prosthetic valve IE than previously. The incidence of.staphylococcal IE has increased. Inhospital mortality remains hig

关键词：感染性心内膜炎微生物学特征全国性调查流行病学阿根廷凝固酶阴性葡萄球菌临床金黄色葡萄球菌草绿色链球菌院内死亡率

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