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Case Reports in Clinical Medicine 2022年第3期11卷 90-93页

作者： Siham Bouchal Naoual Oubelkacem nabila Lahmadi Rhizlane Berradi Faouzi Belahsen Department of Neurology Hassan II University Teaching Hospital Fez Morocco Laboratory of Epidemiology Clinical Research and Health Community Faculty of Medicine and Pharmacy Sidi Mohammed Ben Abdallah University Fez Morocco Department of Hematology Hassan II University Teaching Hospital Fez Morocco

Progressive multifocal leukoencephalopathy is the most common serious complication related to natalizumab. However, serious haematological complications are very uncommon during treatment with natalizumab. Here we reported the case of an 18-year-old man with a 4-year history of relapsing-re- mitting multiple sclerosis. He was treated firstly by Teriflunomide for 1 year, but he presented relapses and his MRI shows new contrast-enhancing lesions. Therefore, we decided to switch from Teriflunomide to Natalizumab. The patient presented with profound anaemia after the 16th infusions treatment with Natalizumab. The patient’s hemoglobin was 3.2 g/dL with a lower blood reticulocyte value. After red cell transfusions and cessation of Natalizumab, anaemia resolved. Natalizumab was changed by an anti-CD20 monoclonal antibody. The patient had a stable course of multiple sclerosis at 13 months after initiation of Rituximab. We should alert clinicians to be aware of the possibility of anaemia during treatment by Natalizumab.

关键词： Anaemia Erythroblasts Haematological Monitoring Multiple Sclerosis Natalizumab

A Modified Fixed Point Method for the Perona Malik Equation

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Journal of Mathematics and System Science 2017年第7期7卷 175-185页

作者： M.R.Amattouch H. Belhadj, N. nabila University of A bdelmalek Essaadi Faculty of sciences and techniques department of mathematics BP.416 Tangier

In this work we present a new method to solve the Perona Malik equation for the image denoising. The method is based on a modified fixed point algorithm which is fast and stable. We discretize the equation using a finite volume method by integrating the equation using a fuzzy measure on the control volume. To make our algorithm move faster in time, we have used an optimized domain decomposition which generalize the wave relaxation method. Several test of noised images illustrate this approach and show the efficiency of the proposed new method.

关键词： Perona Malik equation Fixed point method Fuzzy measure Choquet integral.

Effect of the Variety of Fig Tree on Some Biological Parameters of Ceratitis capitata Wied, 1824 （Diptera： Trypetidae） in Some Orchards in the Kabylie

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Journal of Life Sciences 2012年第3期6卷 312-319页

作者： Sadoudi-Ali Ahmed Djamila nabila Rezoug Ferroudja Saiki Noreddine Soltani M. Mammeri University Tizi-Ouzou 15000 Algeria Dadji Mokhtar University Annaba 23000 Algeria

The Mediterranean fruit fly, Ceratitis capitata Wied. （1824） is one of the most important pest that can infest orchards if its spread is not controlled. Among the preventive measures recommended in the fight against this pest, we are interested in looking for varieties that are less favorable to the development of this pest among different varieties of fig trees in our region. The biological parameters of the fruit fly which were followed in this study are duration of pupation, rate of emergence, sex ratio and longevity of males and females. The results show that these parameters vary depending on the variety of fruit.

关键词： Ceratitis capitata varieties of figs pupae pupation emergence sex ratio longevity.

The Impact of Lean Six Sigma Practices on Physiotherapy Services Quality at UNRWA Healthcare Centers, Gaza Strip, Palestine

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Journal of Biosciences and Medicines 2019年第12期7卷 79-94页

作者： nabila Mohamed Abu Sharikh Majed Mohamed El Farra Samer Abuzerr Khalil Madi Health Department Physiotherapy Division UNRWA Gaza Palestine Department of Business Administration Faculty of Economics and Administrative Sciences Islamic University Gaza Palestine Department of Social and Preventive Medicine School of Public Health University of Montreal Montréal Canada Quality Improvement and Infection Control Unit Ministry of Health Gaza Palestine Business Administration Al-Azhar University Gaza Palestine

Integrating Lean and Six Sigma found a powerful business tool for the strategy improvement process and saving time is produced. The main aim of this study is to identify the impact of Lean Six Sigma (LSS) practices on physiotherapy service quality at healthcare centers of the United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA), using a descriptive-analytical approach. Data were collected using a questionnaire distributed among 49 physiotherapists working at UNRWA healthcare centers as a census sampling method between July 2016 and August 2017, following the stratified random sampling method. The Statistical Package for Social Science (SPSS) was used to analyze the collected data. The results revealed that there was a statistically significant relationship between Lean Six Sigma (LSS) dimensions and the quality of healthcare services provided in physiotherapy units at the UNRWA healthcare centers. Moreover, the application of Lean Six Sigma dimensions was adopted at 81% of UNRWA healthcare centers. Moreover, the percentage of patients’ satisfaction regarding the quality of healthcare services provided in physiotherapy units was 89%. The study emphasized the effectiveness of Lean Six Sigma dimensions application on the quality healthcare services provided in physiotherapy units at the UNRWA healthcare centers. Furthermore, employee training and reward according to a needs assessment to implement Lean Six Sigma successfully is highly recommended.

关键词： Lean Six Sigma Quality Service UNRWA Healthcare Center Physiotherapy

Rituximab for the Treatment of Multiple Sclerosis: A Retrospective Observational Cohort in Morocco

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Case Reports in Clinical Medicine 2022年第10期11卷 448-456页

作者： Siham Bouchal nabila Lahmadi Sara Zejli Naima Chtaou Youssef Hafidi Faouzi Belahsen Department of Neurology Hassan II University Teaching Hospital Fez Morocco Laboratory of Epidemiology Clinical Research and Health Community Faculty of Medicine and Pharmacy Sidi Mohammed Ben Abdellah University Fez Morocco Department of Pharmacology Hassan II University Teaching Hospital Fez Morocco

Background: RITUXIMAB (RTX) is a chimeric anti-CD20 monoclonal antibody that has initially demonstrated efficacy in patients with B-cell lymphoma. Then, over time, it has demonstrated its efficacy in systemic inflammatory diseases and recently in neurological diseases such as multiple sclerosis (MS). Here we describe our experience with rituximab from one MS center from MOROCCO. Objectives: To investigate the safety and efficacy of Rituximab in MS in a Moroccan population. Methods: A retrospective uncontrolled observational single-center study from January 2017 to July 2020, was including all off-label Rituximab-treated patients with MS with at least 6 months of follow-up. Outcome data were collected and evaluated relapse rate, EDSS score, and adverse events (AEs) from the medical charts. Adverse events grade according to the Common Terminology Criteria for Adverse Events. Results: A total of 63 MS patients were treated with RTX, 47 patients were included, while 12 cases had just initiated treatment and 4 cases were lost to follow-up. The mean age of the patients was 39 ± 12 years with a female predominance (F/M: 1.6). All forms of MS were included, 83% of whom had relapsing-remitting MS. The duration of disease progression was 8 ± 5 years. Median EDSS before RTX initiation was 5.5 (0 - 7). 51% of patients were treated with RTX as second-line therapy after failure of other disease-modifying therapies, whereas 34% received it as first-line therapy. The annualized relapse rates decreased from 0.8 to 0.2 after RTX treatment. The Median EDSS remained unchanged at 71%. Radiological stability was noted in 83.7%, while 13.5% had a single new T2 lesion. Infusion-related AEs occurred during 27.6% of infusions and most were mild. Simple infection grades ≤ 2 were noted in 19%. Abortion occurred in only one patient. Conclusion: Our study confirms the usability of rituximab treatment for MS in the MOROCCO healthcare environment.

关键词： B-Lymphocyte CD20 Multiple Sclerosis Rituximab Moroccan Population

Squamous Cell Carcinoma of the Middle Ear: Case Report and Literature Review

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Journal of Cancer Therapy 2024年第9期15卷 303-310页

作者： Mariam Harrak Khouloud Ziani Madiha Chelakhi Othmane Saqri nabila Sellal Mohamed El Hfid Department of Radiotherapy University Hospital Mohamed VI of Tangier Tangier Morocco

Malignant tumors originating from the middle ear are rare. The literature identifies chronic inflammation and Human Papillomavirus (HPV) infection as the most common risk factors. A CT scan to assess bony invasion and an MRI to evaluate soft tissue involvement, depth of invasion, and perineural invasion, followed by a biopsy, are indispensable for diagnosis and treatment. There is no standard treatment for squamous cell carcinoma of the middle ear, however, most reported cases are treated with surgical resection followed by postoperative radiotherapy. Given the challenges of achieving complete surgical excision, radiotherapy plays a crucial role in controlling middle ear cancers, as demonstrated in our case. We present a case of squamous cell carcinoma of the middle ear in a 63-year-old female with a history of chronic suppurative otitis media. The patient underwent a right subtotal petrosectomy without lymph node dissection followed by concurrent chemoradiotherapy. At the one-year follow visit, no recurrence or metastasis was detected.

关键词： Chronic Suppurative Otitis The Middle Ear Squamous Cell Carcinoma Surgery Radiotherapy

Fabrication and Characterization on Physico-Mechanical and Structural Properties of Sawdust Reinforced Acrylonitrile Butadiene Styrene (ABS) Composites

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Materials Sciences and Applications 2020年第9期11卷 644-658页

作者： Budrun Neher nabila Tasnim Nova Rakib Hossain M. A. Gafur Farid Ahmed Department of Physics Jahangirnagar University Dhaka Bangladesh Department of Physics Bangabandhu Sheikh Mujibur Rahman Science & Technology University Gopalganj Bangladesh PP and PDC Bangladesh Council of Scientific and Industrial Research Dhaka Bangladesh

The sawdust reinforced Acrylonitrile Butadiene Styrene (ABS) composites were prepared by using hot press molding machine for five different wt% (0%, 5%, 10%, 15% and 20%) at 180°C temperature and 50 KN load. Sawdust was collected from local saw mill of Savar, Dhaka, Bangladesh and ABS polymer was collected from local market of Dhaka, Bangladesh. In this study, different properties of composites like physical (bulk density and water absorption), mechanical (tensile properties and hardness) and structural (Fourier Transform Infrared Spectroscopy) properties were studied. The bulk density of composites was not altered consistently and it gave greater value for 5% and 20% composites. The water absorption enhanced for all composites with the accumulation of fiber content and soaking time. The reduction of tensile strength and Leeb’s rebound hardness of the composites were observed with the increase of the fiber content in all compositions. Maximum (%) of elongation was found for 5% composite, and then it gradually decreased;however, elastic modulus increased with the increased of fiber content in composites. Fourier Transform Infrared (FTIR) spectroscopy study was done for structural characterization. It was found that there was a new bond (C≡C) stretching formed for 20% composite;moreover, C-H rocking for 0% composite was broken for all other composites after the addition of sawdust in ABS polymer matrix.

关键词： Sawdust-ABS Composite Hot Press Molding Machine Tensile Strength Leeb’s Rebound Hardness FTIR Spectroscopy

Antimicrobial effect of Malaysian vegetables against enteric bacteria

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Asian Pacific Journal of Tropical Biomedicine 2016年第3期6卷 211-215页

作者： Hassanain Al-Talib Norliana Dalila Mohamad Ali Mohamed Harreez Suhaimi Siti Shafika nabila Rosli Nurul Huda Othman Nur Ain Sakinah Mansor Amira Kartini Sulaiman Shah Nurul Syuhada Ariffin Alyaa Al-Khateeb Laboratory Medical Science Cluster Faculty of Medicine Universiti Teknologi MARA (UiTM) Faculty of Medicine Universiti Teknologi MARA (UiTM)

Objective: To investigate the antibacterial activities of green vegetables(pennywort,mint, garlic, parsley and celery) against four common enteric bacteria [Salmonella enterica(ATCC 25957)(S. enterica), Shigella flexneri(ATCC 12022)(S. flexneri),Escherichia coli(ATCC 43889)(E. coli) and Enterobacter cloacae(ATCC 13047)(E. cloacae)] as an alternative medicine for controlling food borne diarrhea disease and the synergistic effect of green vegetables against those ***: Five common vegetables(pennywort, mint, garlic, parsley and celery) were purchased and extracted. The antimicrobial activities of these extracts were tested against four common enteric bacteria(S. enterica, S. flexneri, E. coli and E. cloacae). Ten different concentrations of the extracts(from 640 to 1.25 mg/m L) were prepared and used for the study. The minimal inhibitory concentration(MIC) was determined by the broth dilution method. The antimicrobial activities were assessed by using both well diffusion and disc diffusion ***: Garlic extract showed excellent inhibitory effects on all enteric bacteria. Other plants(parsley, celery, mint and pennywort) were not effective against enteric *** MIC of garlic against S. flexneri and E. cloacae was 40 mg/m L. The MIC of S. enterica and E. coli were 20 and 10 mg/m L, respectively. The performance of the well diffusion method was better than that of the disc diffusion method with clear and sharp inhibition zones of tested bacteria against plant ***: Garlic had excellent antimicrobial effects against enteric bacteria and was recommended to be given to patients with gastroenteritis. The other vegetables(pennywort, mint, parsley and celery) showed no inhibitory effects on enteric bacteria but still can be used for its richness in vitamins and fibers. The performance of the well diffusion method was better than that of the disc diffusion method in detecting the antibacterial effects of green vegetables.

关键词： Antibacterial activities Green vegetables Enteric bacteria Inhibitory effects

A Statistical Approach to Analyze the Factors Affecting Family Planning in Bangladesh

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Open Journal of Statistics 2019年第1期9卷 74-84页

作者： Ataul Mustufa Anik Shabab Noor Islam Shahber Hassan Susmoy Saha Nayema Taskin nabila Department of Statistics Shahjalal University of Science & Technology Sylhet Bangladesh

Family planning is one of the essential tools for reducing maternal and neonatal mortality rate. Several potential factors influence the usage of contraception, and the purpose of the paper is to identify the relevant ones among them. Using the data of BDHS 2014, cross tabulation and the multinomial logistic regression model is used to analyze the association of different factors. The 2014 BDHS gathered data from more than 17,000 families and more than 17,800 married women. There are many factors that can be associated with the application of family planning but among them. Heard about family planning on Newspaper/magazine, Time spending on Television, heard about family planning from media such as Television, Radio, etc., Household has: Radio appeared as the significant determinants of family planning. In this research, it is found that 94.9% did not use family planning where else only 5.1% used family planning. Among those who used family planning methods 32.6% used pills, 16.1% used injections, 7.2% used condoms, 3.2% used female sterilization, 0.6% used male sterilization, etc. Arranging various campaigns and use of mass media is fundamental to raise awareness about family planning.

关键词： Family Planning Practice Factors Contraceptive Prevalence Rate Bangladesh