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A Retrospective Comparative Study between Levosimendan and Adrenaline as a Pharmacological Protocol for the Management of Coronary Artery Bypass Grafting Patients with Low Ejection Fraction: A Friend or Foe

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World Journal of Cardiovascular Surgery 2018年第11期8卷 219-231页

作者： mohammed nabil Abd Al Jawad mohammed S. Shorbagy Department of Cardiothoracic Surgery Ain Shams University Cairo Egypt Department of Anesthesiology Ain Shams University Cairo Egypt

Background: Left ventricular ejection fraction is an independent determinant of the outcome of coronary artery bypass surgery. Low preoperative ejection fraction requires special care in terms of pharmacological and mechanical inotropic support. Adrenaline is the most widely used inotropic drug, while levosimendan is a relatively new inotropic drug in the field of cardiac surgery. In this study, we aimed to evaluate the relative efficacy of levosimendan in low ejection fraction patients undergoing coronary artery bypass grafting (CABG). Methods: A retrospective comparative study was performed with 63 patients who underwent isolated on-pump elective CABG with a preoperative ejection fraction below 40%. Patients were allocated to the adrenaline group (n = 35) and levosimendan group (n = 28). Patients were further stratified according to ejection fraction above 30% and below or equal to 30%. The primary outcome was cardiac-related mortality, while other parameters were considered secondary endpoints. Results: EuroSCORE of the adrenaline group was 3.34 ± 1.26 and for the levosimendan group 3.15 ± 1.42 (p value 0.576). Nine patients of the adrenaline group had new postoperative atrial fibrillation compared to seven patients in the levosimendan group (p value 0.948). Two patients of the adrenaline group had postoperative ventricular arrhythmia compared to only one patient in the other group (p value 0.691). The adrenaline group had higher doses of inotropic support compared to the levosimendan group 210.84 ± 23.74 and 157.4 ± 22.69 ng/kg/min respectively (p value Conclusions: The levosimendan-based protocol failed to improve overall mortality in low ejection fraction patients undergoing CABG. However, this protocol significantly reduced the dose of inotropic and vasoconstrictor support needed, ventilation hours and duration of ICU stay.

关键词： Levosimendan Epinephrine Low Ejection Fraction Coronary Adrenaline

HPCC+：数据中心网络中公平-延迟折中的传输控制协议

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HPCC+：数据中心网络中公平-延迟折中的传输控制协议

作者： mohammed nabil Hazza Ali（纳毕）北京邮电大学

学位级别：硕士

数据中心网络（DCNs）中拥塞控制机制的研究主要集中在如何实现DCNs的三个主要目标:高带宽、低延迟和稳定性。高精度拥塞控制（HPCC）同时实现了这些目标。但是其公平性欠佳。本论文主要研究如何改进HPCC,从而提升其公平性。本研究提出... 详细信息

数据中心网络（DCNs）中拥塞控制机制的研究主要集中在如何实现DCNs的三个主要目标:高带宽、低延迟和稳定性。高精度拥塞控制（HPCC）同时实现了这些目标。但是其公平性欠佳。本论文主要研究如何改进HPCC,从而提升其公平性。本研究提出对HPCC进行有效的调整,对HPCC-WAI（window additive increase）中最重要的参数之一进行了广泛的研究,该参数负责控制并发流数量和收敛速度与公平性之间的权衡。其中的重点是通过更改生成此参数值的公式来找到此参数的最佳值。在WAI值的生成过程中,主要依赖于流的个数,每次流的个数发生变化时,都会生成一个新的WAI值,这一过程影响到公平性。所提出的WAI最优值的关键思想不是完全依赖于流的数量,而是不管流的数量或其数据的大小如何,为WAI找到一个恒定的值,以实现公平性和零队列长度的快速收敛。在仿真中,该方法在通过最佳公平性提高HPCC性能的过程中的实验结果非常令人满意。经过大量观察和评估过程,选择250MB作为WAI的最佳值,这证明该值为HPCC提供了公平性,高链路利用率和零队列长度的最佳值。

关键词：数据中心网络拥塞控制机制 HPCC 窗口加性增加公平性低延迟高利用率

Postoperative Complication in Overweight Patients Undergoing Coronary Artery Bypass Graft Surgery

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World Journal of Cardiovascular Surgery 2019年第6期9卷 53-62页

作者： mohammed Abd Elzaher Abd El Motaleb Tamer Hikal mohammed nabil Abd Al Jawad Hani Metwaly Mohsen Fadala Department of Cardio-Thoracic Surgery National Heart Institute Cairo Egypt Department of Cardio-Thoracic Surgery Ain Shams University Cairo Egypt

Background: Obesity has a great impact on overall mortality and morbidity in cardiac surgery. The magnitude of obesity is defined by means of body mass index (BMI). At this study we aim to correlate between grade of BMI and postoperative complications in patients undergoing coronary revascularization. Methods: A prospective observational study was conducted in Ain Shams University hospitals and the National Heart Institute of Egypt. 98 patients with multi-vessel CAD and candidate for CABG were included in the study and divided into two groups Group I: 53 patients with BMI over 30. Group II: 45 patients with a BMI under 30. The primary endpoint was wound infection and mediastinitis. Secondary endpoints included mortality, prolonged ICU and hospital stay, stroke, renal and hepatic impairment. Results: As regard primary ending point, eight patients of Group I had their wounds infected which is significantly higher than the other group (p-value 0.034). The total ward stay in days was significantly higher in Group I (p-value 0.027). Conclusion: BMI more than 30 is associated with increased rates of wound complications either superficial or deep wound infections. Robust measures should be taken to prevent such grave complications.

关键词： Obesity Coronary Artery Bypass Outcomes

Evaluation of Reticulocyte Hemoglobin Content and Serum Neutrophil Gelatinase-Associated Lipocalin as Predictive Biomarkers of Anemia in Children on Hemodialysis

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Open Journal of Nephrology 2021年第4期11卷 523-537页

作者： Heba Ahmed Donia Manal Abdel El-Salam Gehad nabil mohammed Doaa Aly Abd Elfattah Pediatrics Department Faculty of Medicine (for Girls) Al-Azhar University Cairo Egypt Clinical Pathology Department Faculty of Medicine (for Girls) Al-Azhar University Cairo Egypt

Background: Diagnosis of iron deficiency anemia with currently available tests is rendered difficult in hemodialysis patients. The aim: To investigate the role of reticulocyte Hemoglobin Content (CHr) in the diagnosis of iron deficiency anemia in hemodialysis children in comparison to the used traditional markers and assess the impressiveness and the utility of Neutrophil Gelatinase Associated Lipocalin (NGAL) as a novel biomarker of iron status in those patients. Methods: This study investigated CHr in addition to NGAL serum level in the same line with traditional markers for anemia, including: CBC, serum iron, ferritin, total iron-binding capacity (TIBC), and transferrin saturation (TSAT%). Results: It is more significant that CHr content in hemodialysis children is lower than their controls as they are (27.06 ± 2.90) pg and (32.86 ± 3.59) pg, respectively, p = 0.01. There is no significant difference regarding NGAL between the study groups. Significant negative correlation between CHr with ferritin, urea, creatinine, and positively correlated with iron and RBCS. CHr showed a sensitivity of 90% and specificity of 86.67% to detect iron-deficiency anemia with a cut-off value of 27 pg. Conclusion: CHr is superior to ferritin and TSAT % for the early diagnosis of iron deficiency anemia in hemodialysis children;our results do not support NGAL as a marker of anemia in hemodialysis patients.

关键词： Children Hemodialysis Reticulocyte Hemoglobin Content Neutrophil Gelatinase-Associated Lipocalin

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基于雷达观测的目标跟踪与评估系统

基于雷达观测的目标跟踪与评估系统

作者：那比尔（MAHIEDDINE mohammed nabil）哈尔滨工业大学

学位级别：硕士

多目标跟踪是指在传感器获取的带有噪声的测量基础上,建立被监测的多个目标的轨迹的过程。多目标跟踪对于军队以及民用监视具有重要的实际意义。多目标跟踪的战略目标是从获得的数据中追踪目标,这涉及到众多特别复杂的因素,例如跟踪目... 详细信息

多目标跟踪是指在传感器获取的带有噪声的测量基础上,建立被监测的多个目标的轨迹的过程。多目标跟踪对于军队以及民用监视具有重要的实际意义。多目标跟踪的战略目标是从获得的数据中追踪目标,这涉及到众多特别复杂的因素,例如跟踪目标的数量可变,传感器噪声,错误的警报以及数据关联的不确定性等。针对这些问题,本文选用概率假设密度滤波器作为核心方法,研究实现了以该滤波器为基础的多种状态估计算法。势概率假设密度滤波器也被认为是解决方案之一,但它比PHD滤波器在计算上更为复杂。同样地,我们也在本文中实现了针对该滤波器的状态估计。在概率假设密度滤波的实现方面,本文采用了粒子滤波实现的SMC-PHD滤波器,因为它能够与非线性和非高斯动力学联系在一起。之后,本文主要对四种状态估计方法进行了研究和对比。在多目标轨迹评估方面,本文使用OSPA以获得最佳轨迹集合距离,以评估两个轨迹集合的相似程度。最后,本文将上述算法研究集成于基于雷达传感器的目标跟踪演示系统中,以提供可视化的多目标跟踪结果和算法性能的多角度评估。

关键词：多目标跟踪 PHD滤波器 CPHD滤波器 OSPA 评估雷达

Wheat Genetic Transformation as Efficient Tools to Fight against Fungal Diseases

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Journal of Agricultural Science and Technology(A) 2015年第3期5卷 153-161页

作者： Danielle Christelle Tinak Ekom mohammed nabil Benchekroun Sripada Mahabal Udupa Driss Iraqi Moulay Mustapha Ennaji Laboratory of Virology Microbiology and Quality/Ecotoxicology and Biodiversity Faculty of Sciences and Techniques University Hassan II Mohammedia-Casablanca P.O. Box 146 Quartier Yasmina Mohammedia 20650 Morocco ICARDA-INRA Cooperative Research Project International Center for Agricultural Research in the Dry Area (1CARDA) B.P. 6299 Rabat Morocco Biotechnology Research Unit Institut National de la Recherche Agronomique (INRA) B.P. 415 Avenue de la Victoire Rabat Morocco

Wheat ranks first among cereal crops cultivated in the world. In its production, diseases like powdery mildew, fusarium head blight and rusts caused by fungal pathogens represent a major problem. They produce different symptoms that cause severe crop damage by infecting the spikes, leaves, roots, stems and grains. They are causing losses both by reducing the quantity of the harvested crop and the quality of the product. Quality problems of the harvested product can be due to shrivelled seed, which are frequently found as a consequence of the infection by leaf pathogens, such as mildews, rusts and Septoria. Fusarium head blight is the major culprit for mycotoxin contamination from the harvested grain, causing economic losses and in the worst casing human and animal health problems. In severe epidemics, all these fungal diseases can significantly reduce yield. Resistance to fungi is beneficial not only from a commercial point of view （yield）, but also because of the reduced levels of mycotoxins. The integration of transgenic approaches offers a potential chemical-free and environment-friendly solution for controlling fungal pathogens. This is an essential asset for wheat world food security.

关键词： Crop damages food security transgenic approaches wheat fungal diseases.

Stability of Three-Dimensional Interfacial Waves Under Subharmonic Disturbances

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China Ocean Engineering 2023年第4期37卷 558-567页

作者： nabil ALLALOU mohammed DEBIANE Christian KHARIF Facultéde Physique Universitédes Sciences et de la Technologie Houari Boumediene(USTHB)Algiers 16123Algeria Technopole de Chateau-Gombert Institut de Recherche sur les Phénomènes Hors Equilibre(IRPHE)Marseille 13384France

This study examines the stability regimes of three-dimensional interfacial gravity *** numerical results of the linear stability analysis extend the three-dimensional surface waves results of Ioualalen and Kharif(1994)to three-dimensional interfacial *** approach of the collocation type has been developed for this *** equations of motion are reduced to an eigenvalue problem where the perturbations are spectrally decomposed into normal *** results obtained showed that the density ratio plays a stabilizing *** addition,the dominant instability is of three-dimensional structure,and it belongs to class I for all values of density ratio.

关键词： short-crested interfacial waves linear stability collocation method Padéapproximant

The Mechanical and Crystallographic Evolution of Stipa tenacissima Leaves During In-Soil Biodegradation

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Journal of Renewable Materials 2018年第3期6卷 336-346页

作者： Zakia Khelifi mohammed Amine Allal nabil Abou-bekr Said Taibi Benoit Duchemin Normandy University ULHCNRSLOMC76600 Le HavreFrance University of Tlemcen Lab-EOLEBP 23013000 TlemcenAlgeria

The in-soil biodegradation of Stipa tenacissima(alfa)leaves was ***-linear mechanical testing was performed at various biodegradation *** strength,loading and unloading Young’s moduli and dissipation energy decreased with the burial time,whereas plasticity ***-emission scanning electron microscopy(FE-SEM)showed that the fracture cracks propagated in the longitudinal direction in the raw material,resulting in a fracture mode consisting of a mixture of middle lamella delamination and fiber *** contrast,the cracks were perpendicular to the stem axis in the biodegraded material,demonstrating an important strength loss of the load-bearing *** strength loss was correlated with rapid cellulose degradation.A novel X-ray diffraction(XRD)model was implemented in order to take into account anisotropic size *** the first time,XRD demonstrated the action of biodegradation on unrefined plant tissues under quasi in-situ *** induced a progressive loss of crystalline cellulose accompanied with anisotropic crystallite thinning.

关键词： Alfa mechanical testing FE-SEM XRD biodegradation

Ameliorative properties of Iranian Trigonella foenum-graecum L. seeds and Punica granatum L. peel extracts in streptozotocin-induced experimental diabetic guinea pigs

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Asian Pacific Journal of Tropical Biomedicine 2017年第3期7卷 234-239页

作者： nabil Abdel Salam Ahmed Hasona mohammed Ahmed Qumani Turki Ahmed Alghassab Muath Abdulrahman Alghassab Abdullah Ali Alghabban Department of Biochemistry College of MedicineHa'il UniversityHa'ilSaudi Arabia Department of Chemistry Faculty of ScienceBeni-Suef UniversityBeni-SuefEgypt Department of Pharmacology College of MedicineHa'il UniversityHa'ilSaudi Arabia

Objective: To assess the ameliorative properties of Iranian Trigonella foenum-graecum L.(T. foenum-graecum) seeds and Punica granatum L.(P. granatum) peel extracts against streptozotocin-induced diabetes in male guinea ***: Sixty guinea pigs were divided into six groups(10 guinea pigs per group).Group 1 consisted of normal animals. Groups 2 and 3 were treated with Iranian T. foenum-graecum seeds and P. granatum peel extract alone, respectively. Group 4 was treated with streptozotocin only; whereas Groups 5 and 6 receiving streptozotocin were treated with Iranian T. foenum-graecum seeds and P. granatum peel extract, *** animals were treated for 30 days, and the body weight, blood and liver biochemical parameters were ***: Guinea pigs exposed to streptozotocin showed an alteration in body weight gain, fasting glucose level, kidney function parameters(blood urea nitrogen and creatinine) as well as decreased serum and hepatic total protein level. In addition, it increased the cholesterol and triglyceride level, while decreasing the hepatic glucose-6 phosphate dehydrogenase activity, glycogen, glutathione content and hepatic catalase activity. Oral treatment with T. foenum-graecum seeds and P. granatum peel extracts revealed significant protective properties with respect to body weight gain and other biochemical parameters ***: The Iranian T. foenum-graecum seeds and P. granatum peel extracts are significantly potent in ameliorating diabetic condition induced by streptozotocin and improving various biochemical parameters in serum and liver of guinea pigs.

关键词： Diabetes Iranian Trigonella foenum-graecum Seeds Punica granatum Peel Streptozotocin