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Curcuma wenyujin y. H. Chen et C. Ling n-Butyl Alcohol Extract Inhibits AGS Cell Helicobacter pyloriCagA+VacA+ Promoted Invasiveness by Down-Regulating Caudal Type Homeobox Transcription Factor and Claudin-2 Expression

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Chinese Journal of Integrative Medicine 2020年第2期26卷 122-129页

作者： JIN Hai-feng DAI Jin-feng MENG Li-na LU Bin Department of Gastrointerology the First Affiliated Hospital of Zhejiang Chinese Medical University

Objective:To investigate the effects and possible mechanisms of action of Curcuma wenyujin *** et *** n-Butyl alcohol extract(CWnaE)on repression of human gastric cancer(GC)AGS cell invasion induced by co-culturing with Helicobacter pylori(HP).Methods:AGS cells were cultured with HP of positive or negative cytotoxin-associated gene A(Cag A)and vacuolating cytotoxin gene A(Vac A)expression(Cag A+/-or Vac A+/-)and divided into 5 *** A was cultured without HP as a control,Group B with HPCagA+VacA+,Group C with HPCagA-VacA-,Group D with HPCagA+VacA+and CWnaE,and Group E with HPCag A-Vac Aand ***-tetrazolium bromide(MTT)and tumor invasion assays,examinations of morphology and ultramicroscopic structures,quantitative real-time polymerase chain reaction and Western blots were performed to measure the effects and uncover the mechanisms behind these effects of HPCagA+VacA+and CWnaE on the epithelial-mesenchymal transition(EMT)of AGS ***:The 10%inhibitory concentration of CWnaE against AGS cells after a 48 h incubation was 19.73±1.30μg/m *** AGS cells were elongated after co-culturing with HPCagA+VacA+than after culturing with HPCagA-VacA-.In tumor invasion assays,HPCagA+VacA+significantly enhanced the invasiveness of AGS cells compared to the other experimental groups(all P valuey *** with CWnaE normalized tight junctions and reduced the number of pseudopodia of AGS cells co-cultured with HPCagA+VacA+.HPCagA+VacA+up-regulated zincfinger ebox binding homeobox 1(ZEB1)in AGS cells after co-culturing for 24 *** of caudal type homeobox transcription factor(CDX-2)and claudin-2 was significantly increased by HPCagA+VacA+(Py HPCagA-VacA-.Conclusions:HPCagA+VacA+promoted the invasiveness of AGS cells through up-regulation of ZEB1 transcription and claudin-2 and CDX-2 *** inhibited these effects of HPCagA+VacA+on AGS cells by down-regulating ZE

关键词： Helicobacter pylori gastric cancer AGS zinefinger ebox binding homeobox 1 caudal type homeobox transcription factor claudin・2 Chinese medicine

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虚拟现实技术对脑卒中上肢功能影响的弥散张量成像研究

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中国康复理论与实践 2024年第1期30卷 61-67页

作者：林娜高菡璐卢惠苹陈燕清郑军凡陈述荣福州市第二总医院福建福州市350007

目的采用弥散张量成像观察虚拟现实技术对脑卒中患者上肢功能的效果。方法2021年9月至2023年3月,选取福州市第二总医院收治的脑卒中患者80例,随机分为对照组(n=40)和试验组(n=40)。两组均行常规康复,试验组增加虚拟现实技术康复,共4周... 详细信息

目的采用弥散张量成像观察虚拟现实技术对脑卒中患者上肢功能的效果。方法2021年9月至2023年3月,选取福州市第二总医院收治的脑卒中患者80例,随机分为对照组(n=40)和试验组(n=40)。两组均行常规康复,试验组增加虚拟现实技术康复,共4周。治疗前、治疗4周和随访4周时,采用Fugl-Meyer评定量表上肢部分(FMA-UE)和上肢动作研究量表(ARAT)进行评定。治疗前、治疗4周时,行弥散张量成像(DTI)扫描,测量病灶侧大脑脚和内囊后肢平均各向异性分数(FA)和相对各向异性(RA)。结果两组各脱落2例。治疗4周和随访4周时,两组FMA-UE和ARAT评分均显著升高(F>2.790,P2.297,P21.013,P2.006,P0.362,P<0.05),试验组内囊后肢ΔFA与ARAT治疗前后差值呈正相关(r=0.459,P<0.01)。结论虚拟现实技术可促进脑卒中患者上肢功能改善,可能与内囊后肢传导恢复有关。

关键词：脑卒中上肢虚拟现实技术弥散张量成像

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Two positive effects with one arrow:Modulating crystal and interfacial decoration towards high-potential cathode material

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Journal of Energy Chemistry 2024年第5期92卷 216-223页

作者： Xuexiu Gu Xuan-Wen Gao Dongrun yang Qinfen Gu ySong Hong Chen Tianzhen Ren Wen-Bin Luo Institute for Energy Electrochemistry and Urban Mines Metallurgy School of MetallurgyNortheastern UniversityShenyang 110819LiaoningChina Australian Synchrotron(ANSTO) 800 Blackburn RdClaytonVictoria 3168Australia School of Science and Engineering University of DundeeNethergateDundee DD14HNScotlandUK

As the primary suppliers of cyclable sodium ions,O3-type layer-structured manganese-based oxides are recognized as highly competitive cathode candidates for sodium-ion *** advance the development of high-energy sodium-ion batteries,it is crucial to explore cathode materials operating at high voltages while maintaining a stable cycling *** orbital and electronic structure of the octahedral center metal element plays a crucial role in maintaining the octahedra structural integrity and improving na^(+)ion diffusion by introducing heterogeneous chemical *** by the abundant configuration of extra nuclear electrons and large ion radius,we employed trace amounts of tungsten in this *** obtained cathode material can promote the reversibility of oxygen redox reactions in the high-voltage region and inhibit the loss of lattice ***,the formation of a na_(2)WO_(4) coating on the material surface can improve the interfacial stability and interface ions *** demonstrates an initial Coulombic efficiency(ICE)of 94.6%along with 168.5 mA h g^(-1 )discharge capacity within the voltage range of 1.9-4.35 *** findings contribute to the advancement of high-energy sodium-ion batteries by providing insights into the benefits of tungsten doping and na_(2)WO_(4) coating on cathode materials.

关键词： Sodium ion battery Layer-structured manganese-based oxides Cathodematerial Surface modification Elements doping

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Recent advances in the application of sulfinic acids for the construction of sulfur-containing compounds

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Chinese Chemical Letters 2022年第1期33卷 97-114页

作者： yufen Lv Huanhuan Cui na Meng Huilan yue Wei Wei School of Chemistry and Chemical Engineering Qufu Normal UniversityQufu 273165China Qinghai Provincial Key Laboratory of Tibetan Medicine Research and CAS Key Laboratory of Tibetan Medicine Research Northwest Institute of Plateau BiologyXining 810008China School of Chemistry and Chemical Engineering Shihezi UniversityShihezi 832000China

Sulfur-containing organic compounds display wide applications in the field of materials science,synthetic chemistry,and pharmaceutical ***,numerous synthetic strategies have been developed for the synthesis of sulfur-containing compounds in synthetic *** recent years,the utilization of sulfinic acids as versatile synthons has emerged as attractive and powerful approach to access various organosulfur compounds through sulfonylation,sulfinylation or sulfenylation *** this review,we summarized the recent progress in the construction of various sulfur-containing compounds from sulfininc *** examples of substrates and the related reaction mechanisms are described *** review intends to provide readers a comprehensive understanding on the synthesis of sulfur-containing molecules from sulfinic acids and provide help for future synthetic research.

关键词： Sulfur-containing compounds Sulfinic acids Sulfonylation Sulfinylation Sulfenylation

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Terrain-influenced wind flow of the Qitai radio telescope site

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Journal of Mountain Science 2023年第11期20卷 3173-3185页

作者： HE Fei-long XU Qian WANG na XUE Fei WANG Hui Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Key Laboratory of Radio Astronomy Chinese Academy of SciencesUrumqi 830011China Xinjiang Key Laboratory of Radio Astrophysics Urumqi 830011China University of Chinese Academy of Sciences Beijing 100049China

The wind environment of a site is one of the important factors affecting the observation performance of large aperture and high-performance radio *** the relationship between the effects of different terrains on wind flow is important to optimize the wind environment of the *** terrain of the Qitai radio telescope(QTT)site located in east Tianshan Mountains at an elevation of about 1800 m was used to study the wind flow in the adjacent zone of antenna based on numerical *** area from 600m south to 600m north of the antenna is defined as the antenna adjacent zone,and three groups of boundaries with different terrains are set up upstream and downstream,*** the zone where the antenna is located is a slope terrain,in order to verify the influence of terrain on the wind flow and to clarify the relationship between the influence of boundary terrain on the wind flow,a control group of horizontal terrain is *** simulation results show that the wind flow is mainly influenced by the *** highest elevation of the upstream and downstream boundary terrains affects the basic wind *** upstream boundary terrain has a greater impact on wind flow than the downstream boundary *** addition,the wind speed profile index obtained by numerical simulation is smaller than the actual index for the wind from ***,the wind speed at the upper level(about 100 m)obtained by inversion based on the measured wind speed at the bottom(about 10 m)is also smaller than the actual wind speed.

关键词： Radio telescope site Terrain Wind flow characteristic Numerical simulation

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Decomposition of labile and recalcitrant coniferous litter fractions affected by temperature during the growing season

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Journal of Forestry Research 2020年第4期31卷 1115-1121页

作者： Veronika Jílková Kristyna Dufková Tomás Cajthaml Na Sádkách 7CeskéBudějovice 37005Czech Republic Faculty of Science Masaryk UniversityKotlárská267/2Brno 61137Czech Republic Institute for Environmental Studies Charles University in PragueBenátská2Prague 12801Czech Republic Institute of Microbiology Czech Academy of SciencesVídeňská1083Prague 14220Czech Republic

Temperate coniferous forest soils are considered important sinks of soil organic carbon(C).Fresh C inputs may,however,affect soil microbial activity,leading to increased organic matter decomposition and carbon dioxide *** consists of labile and recalcitrant fractions which are thought to be utilized by distinct microbial communities and at different rates during the growing *** this study,we incubated the whole litter(LC+RC),the labile(LC)and the recalcitrant(RC)fractions with the coniferous soil at two temperatures representing spring/autumn(10℃)and summer(20℃)for one *** respiration and microbial community composition were regularly determined using phospholipid fatty acids as *** LC fraction greatly increased soil respiration at the beginning of the incubation period but this effect was rather *** effect of the RC fraction persisted longer and,together with the LC+RC fraction,respiration increased during the whole incubation *** of the RC fraction was more strongly affected by higher temperatures than decomposition of the more labile fractions(LC and LC+RC).However,when we consider the relative increase in soil respiration compared to the dH2 O treatment,respiration increased more at a lower temperature,suggesting that available C is more important for microbial metabolism at lower *** C was added only once in our study,no changes in microbial community composition were detected,possibly because the microbial community is adapted to relatively low amounts of additional C such as the amounts naturally found in litter.

关键词： Temperate forest Picea abies Soil respiration Hot water-extractable carbon PLFA (phospholipid fatty acids)

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盘锦水稻田碳通量变化特征研究

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中国稻米 2024年第1期30卷 84-92,97页

作者：邹旭东李荣平曹士民蔡福米娜王笑影盘锦市气象局辽宁盘锦124010 中国气象局沈阳大气环境研究所沈阳110166

为了揭示我国北方水稻田生态系统的碳通量动态特征及其对气象因子的响应,利用盘锦市水稻田生态系统观测站2018—2020年净碳交换量(NEE)观测数据,分析盘锦市水稻田NEE年变化、日变化特征,以及植被总初级生产力(GPP)日变化和季节变化;对比... 详细信息

为了揭示我国北方水稻田生态系统的碳通量动态特征及其对气象因子的响应,利用盘锦市水稻田生态系统观测站2018—2020年净碳交换量(NEE)观测数据,分析盘锦市水稻田NEE年变化、日变化特征,以及植被总初级生产力(GPP)日变化和季节变化;对比NEE与风向、净辐射关系,最后按季节对比地温对植被呼吸(Reco)的影响,计算生态系统呼吸温度敏感性(Q_(10))。结果表明,NEE的年总量都为负值,其中2018年NEE总量最大,为-574.09 g C/(m^(2)·y);NEE的年变化与风速呈正相关,与日照呈负相关;NEE的日变化为“U”型,GPP的日变化为倒“U”型,中午达到峰值,日变化值在夏季最大;NEE高值对应的风向是W、WSW、SW和NE、ENE;NEE低值对应的风向是SSE、S和NNW、NW;NEE绝对值随净辐射的增加而增大,有时出现NEE峰值滞后于净辐射的情况。GPP年值呈下降趋势,Reco年际变化较小。夏季Reco比其他季节高2.0~6.0倍。2019夏季呼吸强度随地温增值达到0.85 g C/(m^(2)·d)。计算2019年夏季Q_(10)值达到4.84。2018年夏季平均气温较高、温度日较差较小、风速较大共同促成了NEE2018年高值。而2020年6—7月降水量偏少造成2020年NEE值偏低。Reco与土壤温度存在明显的指数关系。Q_(10)值在夏季最高,是其他季节的1.9~2.6倍。

关键词：水稻田碳通量变化特征气象因子盘锦市

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蒙药材蜀葵花质量标准研究

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北方药学 2024年第2期21卷 1-3,11页

作者：岳海塔娜高寒郭宝凤内蒙古自治区药品检验研究院内蒙古呼和浩特010020 内蒙古自治区中蒙药标准研究重点实验室内蒙古呼和浩特010020

目的:建立蒙药材蜀葵花的定性定量评价方法。方法:采用显微法、薄层色谱法建立蜀葵花的定性鉴别方法,2020年版《中国药典》方法测定水分、总灰分、酸不溶性灰分、浸出物、含量测定,采用高效液相色谱法建立蜀葵花中山柰素的定量分析方法... 详细信息

目的:建立蒙药材蜀葵花的定性定量评价方法。方法:采用显微法、薄层色谱法建立蜀葵花的定性鉴别方法,2020年版《中国药典》方法测定水分、总灰分、酸不溶性灰分、浸出物、含量测定,采用高效液相色谱法建立蜀葵花中山柰素的定量分析方法。结果:建立的薄层色谱法斑点清晰,重复性好,可用于对7批蜀葵花药材的定性鉴别。测得7批样品水分、总灰分、酸不溶性灰分、浸出物含量。蜀葵花中山柰素含量测定的标准曲线为y=0.0471X-0.0288,线性范围为10.81ng~135.13 ng,相关系数为0.9999,精密度RSD=0.87%,加样回收率为102.03%,RSD=1.82%。7批蜀葵花中山柰素含量为0.12%~0.49%。结论:建立的显微法、薄层色谱法可用于对蜀葵花药材的定性鉴别,高效液相色谱法简便、可行,可用于蜀葵花中山柰素的含量测定。

关键词：蜀葵花山柰素显微鉴别法薄层色谱鉴别法高效液相色谱法质量标准

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Evaluation of natural forest regeneration as a part of land restoration in the Khentii massif,Mongolia

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Journal of Forestry Research 2020年第5期31卷 1773-1786页

作者： David Juricka Antonın Kusbach Jana Parılkova Jakub Houska Pavlına Ambrozova Vaclav Pecina Zdena Rosicka Martin Brtnicky Jindrich Kynicky Department of Geology and Pedology Faculty of Forestry and Wood TechnologyMendel UniversityZemedelska 161300 BrnoCzech Republic Department of Forest Botany Dendrology and GeobiocoenologyFaculty of Forestry and Wood TechnologyMendel UniversityZemedelska161300 BrnoCzech Republic Faculty of Civil Engineering Institute of Water StructuresBrno University of TechnologyZizkova 1760200 BrnoCzech Republic Central European Institute of Technology Brno University of TechnologyPurkynova 656/12361200 BrnoCzech Republic

Forest stands in the semi-arid environment of northern Mongolia have an essential role in controlling ongoing desertification in the surrounding *** the last decade,the total forest area has decreased *** aim of this study was to evaluate the potential of natural regeneration as an essential element for ensuring sustainability of these *** on field measurements from 120 plots in six sites,our assessment tool revealed five qualitative categories of forest regeneration,allowing us to assess impacts of both grazing and environmental conditions on the regeneration *** is a crucial factor and adversely affects *** sites with relatively low grazing intensity,low soil moisture levels represent the main reason for reduced *** approach to classification proposed in this study allows for the identification and interpretation of stand conditions where natural regeneration has *** study provides an important foundation to inform decisionmaking related to land protection and restoration *** findings could be used in comparative studies and,importantly,may aid further mapping of Mongolian forests.

关键词： Mongolia natural forest regeneration Seedlings Larix sibirica Land restoration Desertification

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水泥生料成分的近红外光谱分析方法研究

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激光与红外 2024年第4期54卷 599-606页

作者：王译那郭迎庆王一帆肖航赵志张雷南京林业大学江苏南京210037 山东师范大学山东济南250358 山东大学山东济南250061

水泥是一种重要的基础建筑材料,对社会生产有着重大的影响,实现水泥生料成分的快速检测对建筑行业的发展具有重大意义。本文基于近红外光谱分析方法研究了水泥生料中的Al_(2)O_(3)、Fe_(2)O_(3)成分的含量检测,首先通过联合X-y距离划分... 详细信息

水泥是一种重要的基础建筑材料,对社会生产有着重大的影响,实现水泥生料成分的快速检测对建筑行业的发展具有重大意义。本文基于近红外光谱分析方法研究了水泥生料中的Al_(2)O_(3)、Fe_(2)O_(3)成分的含量检测,首先通过联合X-y距离划分法对样品集进行划分,然后对训练集采用不同光谱预处理方法进行处理,最后采用偏最小二乘回归和支持向量回归分别对近红外光谱数据建立预测模型,并对预测结果进行分析比较。研究结果表明,采用S-G平滑预处理和偏最小二乘回归建模的近红外光谱分析方法检测效果较佳,Al_(2)O_(3)检测模型的决定系数R2为0895,预测均方根误差(RMSEP)为0072;Fe_(2)O_(3)检测模型的决定系数R2为0732,RMSEP为0023。研究结果为水泥生料成分的检测提供了有效的分析方法,促进了水泥行业的进一步发展。

关键词：近红外光谱水泥生料成分检测光谱预处理预测模型

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