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Diagnosing the Dynamic and Thermodynamic Effects for the Exceptional 2020 Summer Rainy Season in the Yangtze River Valley

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Journal of Meteorological Research 2022年第1期36卷 26-36页

作者： na WEN Shujie LIU laurent Z.X.LI College of Atmospheric Sciences Nanjing University of Information Science&TechnologyNanjing 210044China Key laboratory of Meteorological Disaster of Ministry of Education Nanjing University of Information Science&TechnologyNanjing 210044China Qingdao Engineering Technology Research Center for Meteorological Disaster Prevention Qingdao Meteorological BureauQingdao 266003China laboratoire de Météorologie Dynamique Centre National de la Recherche ScientifiqueSorbonne UniversitéEcole Normale SupérieureEcole PolytechniqueParis 75252France

An exceptional rainy season occurred in the Yangtze River valley of eastern China in June-July *** relative importance of the dynamic and thermodynamic effects on this unusual event is evaluated through the budget equations of moisture and moist static energy(MSE).The moisture budget analysis suggests that the thermodynamic effect contributes to the precipitation anomaly by 8.5%through the advection of abnormal water vapor by mean vertical motion,while the dynamic effect,related to water vapor advection by anomalous vertical motion,has the dominant *** MSE budget analysis further reveals that the anomalous vertical motion is both constrained by the dynamic effect related to changes in atmospheric circulation and the thermodynamic effect related to changes of the atmospheric thermal state,with a ratio of thermodynamic versus total effects estimated at 45.3%.The dynamic effect is linked to the advection of warm and humid air by the abnormal southwesterly wind,which is related with an anomalous anticyclone over the Philippine *** thermodynamic effect is partly induced by the positive advection of anomalous MSE(mainly latent energy)by the mean vertical *** analysis of the dynamic and thermodynamic effects is useful to understand the underlying physical mechanisms leading to the unusual rainy season in the Yangtze River valley in summer *** is also helpful to put forward a few speculations on the potential role of global warming whose primary effect is,after all,to change the thermal state of the atmosphere.

关键词： exceptional rainfall Yangtze River valley global warming dynamic and thermodynamic effects

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多花黄精中果聚糖产物的抗疲劳与改善肠道菌作用研究

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南京中医药大学学报 2024年第5期40卷 494-502页

作者：王娜刘涛马畅虞晓弦嵇晶王令充程建明南京中医药大学药学院江苏南京210023 江苏省经典名方工程技术研究中心江苏南京210023

目的研究多花黄精精制多糖的结构特征并探究其抗疲劳及改善肠道菌作用,为以多花黄精精制多糖为功能性成分的产品开发提供理论依据。方法采用PMP柱前衍生化-高效液相色谱法、三甲基硅醚衍生化-气相色谱法等方法对多花黄精精制多糖进行化... 详细信息

目的研究多花黄精精制多糖的结构特征并探究其抗疲劳及改善肠道菌作用,为以多花黄精精制多糖为功能性成分的产品开发提供理论依据。方法采用PMP柱前衍生化-高效液相色谱法、三甲基硅醚衍生化-气相色谱法等方法对多花黄精精制多糖进行化学表征;采用小鼠负重游泳试验结合生化指标评价其抗疲劳作用;采用16S rRna肠道菌群测序研究多花黄精精制多糖的改善肠道菌作用。结果获得的多花黄精精制多糖是一种果聚糖产物,且含有少量葡萄糖(Glc)、半乳糖(Gal)、阿拉伯糖(Ara)、甘露糖(Man)、鼠李糖(Rha)和半乳糖醛酸(Gala),其相对分子质量在0.4~285 kDa内,主要组分的分子量在3 kDa左右。与模型组比较,多花黄精精制多糖高剂量组能明显延长小鼠的力竭游泳时间(Pla(Plassified_f_Eggerthelaceae)和魏斯氏菌属(g_Weissella)相对丰度(P<0.05)。结论确定了多花黄精精制多糖的化学组成,并证明了该多糖具有较好的抗疲劳功效,能促进肠道中益生菌生长,为以多花黄精精制多糖作为功能性成分的产品开发提供依据。

关键词：多糖多花黄精抗疲劳活性结构表征肠道菌群

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年龄对二尖瓣置换术后心脏自主神经功能影响

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临床军医杂志 2024年第9期52卷 892-895+901页

作者：刘俊鹭王镜涵王玥武敏李保银秦娜娜北部战区总医院麻醉科中国医科大学研究生院北部战区总医院心血管内科北部战区总医院心血管外科辽宁中医药大学

目的探讨不同年龄段因退行性二尖瓣关闭不全行二尖瓣置换术后患者的心率变异性(HRV)的数据，评估年龄对术后心脏自主神经功能的影响。方法回顾性分析自2020年4月至2023年6月在北部战区总医院住院因退行性二尖瓣关闭不全行二尖瓣置换的... 详细信息

目的探讨不同年龄段因退行性二尖瓣关闭不全行二尖瓣置换术后患者的心率变异性(HRV)的数据，评估年龄对术后心脏自主神经功能的影响。方法回顾性分析自2020年4月至2023年6月在北部战区总医院住院因退行性二尖瓣关闭不全行二尖瓣置换的391例患者的临床资料。根据患者的年龄将其分为A组(年龄50～59岁，n=146)、B组(年龄60～69岁，n=196)及C组(年龄70～79岁，n=49)。比较各组患者术前7 d及术后7 d动态心电图HRV的指标，包括均值标准差(SDANN)、总体标准差(SDNN)、标准差均值(SDNNindex)、相邻两个RR间期差值>50 ms(PNN50)、差值的均方根(rMSSD)。比较各组患者心脏超声参数指标，包括左室舒张末内径(LVIDD)、左室后壁厚度(LVPWT)、室间隔厚度(IVST)、左房内径(la)。结果术后，A组患者心功能指标LVIDD高于B组、C组，LVPWT、IVST、la均低于B组、C组，且B组IVST低于C组，差异均有统计学意义(P0.05);术后，各组SDNN、SDANN、SDNNindex均低于各组术前，且A组的SDNN、SDANN、SDNNindex、rMSSD、PNN50均高于B组、C组，B组各指标均高于C组，差异均有统计学意义(P<0.05)。结论退行性二尖瓣关闭不全患者行二尖瓣置换术后，随着年龄的增加，自主神经功能受损、心脏储备力减退，对其术后恢复及生存质量均有影响。

关键词：心率变异性年龄二尖瓣置换术后自主神经系统

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Relationship between microorganisms in coronary atheromatous plaques and periodontal pathogenic bacteria

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Chinese Medical Journal 2008年第16期121卷 1595-1597页

作者： ZHANG Yuan-ming ZHONG Liang-jun LIANG Ping LIU Hua MU la-ti AI Si-ka-er Centre of Cardiology First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 China Department of Stomatology First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 China

Inflammation plays an important role in the pathogenesis .of atherosclerosis, and low-grade chronic systemicinflammation is thought to be related to adverse cardiovascular outcomes,In the past decade, epidemiological studies have repeatedly shown an association between coronary heart disease and periodontal disease. Observational studies have shown that periodontitis is associated with an increased risk of myocardial infarction and stroke, although a causal link has not yet been proven.

关键词： cardiovascular diseases periodontitis polymerase chain reaction Dna sequencing

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Hot corrosion mechanism of yttria-stabilized zirconia powder in the presence of molten na_(2)SO_(4)+V_(2)O_(5) salts

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Rare Metals 2021年第5期40卷 1307-1316页

作者： Jhonattan De la Roche Juan Manuel Alvarado-Orozco Alejandro Toro Tribology and Surfaces Group Universidad Nacional de ColombiaMedellin 050041Colombia Centro de Ingeniena y Desarrollo Industrial-CIDESI Queretaro 76125Mexico Consorcio de Manufactura Aditiva-CONMAD Queretaro 76125Mexico

The hot corrosion behavior of yttria-stabilized zirconia(YSZ)powder specimens exposed to na_(2)SO_(4)/V_(2)O_(5) salts mixtures at high temperature was *** tests were carried out at 1000℃ for 10 h,the salt concentrations varied from 0.1 wt%to 1.00 wt%,and the na_(2)SO_(4)/V_(2)O_(5) mass ratios were between 0.20 and 0.44 following a factorial design 22.X-ray diffraction(XRD)analyses of the tested samples showed with a confidence of95%that the mixture composed of 32 wt%na_(2)SO_(4)+68 wt%V_(2)O_(5),and 1.00 wt% salt concentration led to high destabilization of the t’-YSZ phase and formation of YVO_(4) products.A second set of experiments were conducted to assess the influence of temperature on the hot corrosion response of the YSZ in the range between 490 and 1100℃.Thermogravimetric analysis(TGA)experiments and Rietveld adjustments of XRD patterns showed that the mass loss of the samples varied with testing temperature and also that the major destabilization of tetragonal phase occurred at 900℃.

关键词： Hot corrosion Molten salts Yttria-stabilized zirconia Thermal barrier coatings

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Inoculation with Phosphate-Solubilizing Fungi Diversifies the Bacterial Community in Rhizospheres of Maize and Soybean

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Pedosphere 2007年第2期17卷 191-199页

作者： WANG Guang-Hua JIN Jian XU Mei-na PAN Xiang-Wen C. TANG laboratory of Black Soil Ecology Northeast Institute of Geography and Agroecology Chinese Academy of Sciences Harbin 150081 （China）. Department of Agricultural Sciences La Trobe University Bundoora Vic 3086 （Australia）

Application of phosphate-solubilizing microorganisms (PSMs) has been reported to increase P uptake and plant growth. However, no information is available regarding the ecological consequences of the inoculation with PSMs. The effect of inoculation with phosphate-solubilizing fungal (PSF) isolates Aspergillus niger P39 and Penicillium oxalicum P66 on the bacterial communities in the rhizospheres of maize (Zea mays L. 'Haiyu 6') and soybean (Glycine max Merr. 'Heinong 35') was examined using culture-dependent methods as well as a culture-independent method, polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE). Compared with the control, the number of culturable microbes for soybean was significantly greater with P39, whereas for maize, the same was significantly greater with P66. In addition, a greater number of microbes were found in the rhizosphere of maize compared with soybean. The fingerprint of DGGE for 16S rDna indicated that inoculation with PSF also increased bacterial communities, with the P66 treatment having higher numbers of DGGE bands and a higher Shannon-Weaver diversity index compared with P39; the composition of the microbial community was also more complex with the P66 treatment. Overall, complex interactions between plant species and exotic PSMs affected the structure of the bacterial community in the rhizosphere, but plant species were more important in determining the bacterial community structure than the introduction of exotic microorganisms.

关键词： bacterial community diversity PCR-DGGE phosphate-solubilizing fungus rhizosphere

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Potential Alzheimer’s disease therapeutic nano-platform: Discovery of amyloid-beta plaque disaggregating agent and brain-targeted delivery system using porous silicon nanoparticles

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Bioactive Materials 2023年第6期24卷 497-506页

作者： Jaehoon Kim Hyeji Um na Hee Kim Dokyoung Kim Department of Biomedical Science Graduate SchoolKyung Hee UniversitySeoul02447Republic of Korea Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical Science Institute Kyung Hee UniversitySeoul02447Republic of Korea Department of Anatomy and Neurobiology College of MedicineKyung Hee UniversitySeoul02447Republic of Korea Center for Converging Humanities Kyung Hee UniversitySeoul02447Republic of Korea KHU-KIST Department of Converging Science and Technology Kyung Hee UniversitySeoul02447Republic of Korea UC San Diego Materials Research Science and Engineering Center 9500 Gilman Drive La JollaCA92093USA

There has been a lot of basic and clinical research on Alzheimer’s disease(AD)over the last 100 years,but its mechanisms and treatments have not been fully *** some controversies,the amyloid-beta hypothesis is one of the most widely accepted causes of *** this study,we disclose a new amyloid-beta plaque disaggregating agent and an AD brain-targeted delivery system using porous silicon nanoparticles(pSiNPs)as a therapeutic nano-platform to overcome *** hypothesized that the negatively charged sulfonic acid functional group could disaggregate plaques and construct a chemical *** a result of the in vitro assay of amyloid plaques and library screening,we confirmed that 6-amino-2-naphthalenesulfonic acid(Ana)showed the highest efficacy for plaque disaggregation as a hit *** confirm the targeted delivery of Ana to the AD brain,a nano-platform was created using porous silicon nanoparticles(pSiNPs)with Ana loaded into the pore of pSiNPs and biotin-polyethylene glycol(PEG)surface *** resulting nano-formulation,named Biotin-CaCl2-Ana-pSiNPs(BCAP),delivered a large amount of Ana to the AD brain and ameliorated memory impairment of the AD mouse model through the disaggregation of amyloid plaques in the *** study presents a new bioactive small molecule for amyloid plaque disaggregation and its promising therapeutic nano-platform for AD brain-targeted delivery.

关键词： Alzheimer’s disease Plaques disaggregation nanotherapeutics Brain-targeted drug delivery Porous silicon nanoparticles

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Spatiotemporal patterns of sediment deposition on the northern slope of the South China Sea in the last 150,000 years

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Journal of Palaeogeography 2021年第3期10卷 399-415页

作者： Zhe Hu Bao-Qi Huang Le-Jun Liu na Wang Key laboratory of Orogenic Belts and Crustal Evolution MOESchool of Earth and Space SciencesPeking UniversityBeijing 100871China Marine Engineering Environment Center First Institute of OceanographyMinistry of Natural ResourcesQingdao 266061Shandong ProvinceChina School of Urban Planning and Design Shenzhen Graduate SchoolPeking UniversityShenzhen 518055Guangdong ProvinceChina

The source-to-sink system of the northern South China Sea(SCS) has been widely discussed during the past few decades. Sr–Nd isotope, clay minerals and trace elements were extensively used as the proxies of sediment provenance, however, still little is known about the transport processes and controlling mechanisms on detailed spatiotemporal scales due to the limitations of these methods. Here we put forward the new provenance proxies RAkand RKCNbased on major element compositions to study the spatiotemporal changes in sediment provenance since 150 ka mainly from four sites, DLW3101, MD12-3429, ZHS-176 and MD12-3432, which are located on the northern SCS continental slope. Our results show that, spatially, the pathways and intensities of contour currents and gravity flows play important roles in sediment transport. For alongslope processes, the South China Sea Branch of Kuroshio Current(SCSBKC) and the Deep Water Current(DWC) transport sediments from southwestern Taiwan,while the Intermediate Water Current(IWC) can carry sediments from Hainan, the Red River or the Indochina Peninsula. For downslope processes, gravity flows transport materials from the Pearl River delta and shelf to the slope. Moreover, seafloor bathymetry influences sediment transport by altering the pathways of ocean ***, the impacts of sea level and monsoon rainfall fluctuations are always superimposed over the last 150 ka. Sea level fluctuations could significantly change the distance from the Pearl River estuary to the slope, while variations in the East Asian summer monsoon(EASM) rainfall would affect continental erosion rates in the source regions.

关键词： South China Sea Sediment transport Element composition Ocean current Sea level Quaternary

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Complete Mitochondrial Genome of the Steppe Ribbon Racer(Psammophis lineolatus):The First Representative from the Snake Family Psammophiidae and its Phylogenetic Implications

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Asian Herpetological Research 2021年第3期12卷 295-307页

作者： Minli CHEN Jinlong LIU Jun LI na WU Xianguang GUO Chengdu Institute of Biology Chinese Academy of SciencesChengdu 610041SichuanChina University of Chinese Academy of Sciences Beijing 100049China College of Life Science and Technology Xinjiang UniversityUrumqi 830046XinjiangChina

Comparisons of vertebrate mitochondrial genomes(mitogenomes)may yield significant insights into the evolution of organisms and ***,no complete mitogenome from the snake family Psammophiidae has been *** this study,we sequenced and annotated the complete mitogenome of Psammophis lineolatus,representing the first mitogenome of *** total length is 17166 bp,consisting of 13 protein-coding genes(PCGs),22 transfer Rnas(tRnas),two ribosomal Rnas(12 S rRna and16 S rRna),and duplicate control regions(CRs).This gene arrangement belongs to the TypeⅢpattern,which is a widely shared gene order in Alethinophidian *** tRnas exhibit cloverleaf structures with the exception of tRna-Ser^(AGY) and tRna-Pro,which lack a dihydrouridine(DHU)arm/stem and TΨC loop,*** 13 PCGs include five start codons(ATG,GTG,ATA,ATT,and ATC),two complete stop codons(TAA and AGG),and two incomplete stop codon(T--and TA-).In addition,the ka/Ks ratios indicate that all PCGs had undergone a strong purifying *** types of CR domains rearrangement occurred among eight species of *** phylogenetic reconstructions with both Bayesian inference and maximum likelihood methods support the placement of Psammophiidae in the Elapoidea superfamily,with Homalopsidae being the sister taxon to Elapoidea and ***,the sister taxon of Psammophiidae is unclear due to the availability of Elapoidea mitogenomes being limited to the family *** mitogenomes from different taxonomic groups in Elapoidea are needed to better understand the phylogenetic relationships within Elapoidea.

关键词： mitochondrial genome phylogenetic relationships Psammophis lineolatus Psammophiidae purifying selection

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Solvent extraction of Ce(Ⅲ) and Pr(Ⅲ) with P507 using SiC foam as a static mixer

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Journal of Rare Earths 2022年第4期40卷 676-686,I0006页

作者： Ye Zhang Yong Gao Peng Wang Duo na Zhenming Yang Jinsong Zhang School of Materials Science and Engineering Northeastern UniversityShenyang 110819China Shenyang national laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China

Extraction reactor is a major research area of interest within the field of rare earths extraction and *** foam offers excellent material characteristics as well as three-dimensional(3-D) reticulated structure;however,very little research has been carried out on its application in extraction reactor so *** this work,a static mixer reactor based on SiC foam was designed and demonstrated to extract and separate Ce(Ⅲ) and Pr(Ⅲ) from nitric acid media by using 2-ethylhexyl phosphoric acid mono-2-ethylhexyl ester(P507) as *** structure-performance relationship between SiC foam and extraction performance was studied by experiment combined with computational fluid dynamics(CFD)*** experiment data are in good agreement with the simulation *** experiment by using a Kenics mixer was carried out,and SiC foam shows better extraction and mass transfer *** the optimal structural SiC foam(pore size D=2.3 mm,open porosity ε=85%,foam length L=80 mm),high extraction efficiency η(Pr(Ⅲ):94.6%,Ce(Ⅲ):88.5%) and separation factor β(2.27) between Ce(Ⅲ) and Pr(Ⅲ) is achieved at a high total throughput of 200 mL/***,overall volumetric mass transfer coefficient K_(L)a of Pr(Ⅲ) and Ce(Ⅲ) are 0.519 and 0.378 s^(−1) at the residence time τ of 3.6 s,respectively,which reach the high level of microchannel reactors and are better than conventional extractors and other static *** foam is found to be applicable as a static mixer for efficient and high-throughput extraction and separation of rare earths.

关键词： SiC foam Extraction Static mixer Simulation Rare earths

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