检索结果-南通市图书馆

Gut microbiota induced abnormal amino acids and their correlation with diabetic retinopathy

International Journal of Ophthalmology(English edition) 2024年第5期17卷 883-895页

作者： Sheng-Qun Jiang Su-na Ye Yin-Hua Huang Yi-Wen Ou ke-Yang Chen Jian-Su Chen Shi-Bo Tang Aier Eye Hospital Jinan UniversityGuangzhou 510000Guangdong ProvinceChina Aier Eye Institute and Changsha Aier Hospital Changsha 410000Hunan ProvinceChina The First Affiliated Hospital of Bengbu Medical University Bengbu 233000Anhui ProvinceChina School of Public Health Anhui Medical UniversityHefei 230000Anhui ProvinceChina

AIM:To explore the correlation of gut microbiota and the metabolites with the progression of diabetic retinopathy(dR)and provide a novel strategy to elucidate the pathological mechanism of ***:The fecal samples from 32 type 2 diabetes patients with proliferative retinopathy(PdR),23 with nonproliferative retinopathy(NPdR),27 without retinopathy(dM),and 29 from the sex-,age-and BMI-matched healthy controls(29 HC)were analyzed by 16S rdna gene *** fecal samples from PdR,dM,and HC groups were assayed by untargeted *** metabolites were measured using liquid chromatographymass spectrometry(LC-MS)*** between gut microbiota and fecal metabolites were ***:A cluster of 2 microbiome and 12 metabolites accompanied with the severity of dR,and the close correlation of the disease progression with PdR-related microbiome and metabolites were *** be specific,the structure of gut microbiota differed in four *** and richness of gut microbiota were significantly lower in PdR and NPdR groups,than those in dM and HC groups.A cluster of microbiome enriched in PdR group,including Pseudomonas,Ruminococcaceae-UCG-002,Ruminococcaceae-UCG-005,Christensenellaceae-R-7,was *** analysis showed that the glucose and nicotinate degradations were significantly higher in PdR group than those in HC ***,serine,ornithine,and arachidonic acid were significantly enriched in PdR group,while proline was enriched in HC *** analysis illustrated that arginine biosynthesis,lysine degradation,histidine catabolism,central carbon catabolism in cancer,d-arginine and d-ornithine catabolism were elevated in PdR *** analysis revealed that Ruminococcaceae-UCG-002 and Christensenellaceae-R-7 were positively associated with L-arginine,ornithine levels in fecal ***:This study elaborates the different microbiota structure in the gut from four *** relative abundance of

关键词： proliferative retinopathy gut microbiota Ruminococcaceae amino acid metabolism arginine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

GLOBAL UNIQUE SOLUTIONS FOR THE INCOMPRESSIBLE MHd EQUATIONS WITH VARIABLE dENSITY ANd ELECTRICAL CONdUCTIVITY

引用

Acta Mathematica Scientia 2024年第5期44卷 1747-1765页

作者： Xueli ke School of Mathematics and Computational Science Xiangtan UniversityXiangtan411105China School of Mathematics and Information Science Henan Polytechnic UniversityJiaozuo454000China

We study the global unique solutions to the 2-d inhomogeneous incompressible MHd equations,with the initial data(u0,B0)being located in the critical Besov space■and the initial densityρ0 being close to a positive *** using weighted global estimates,maximal regularity estimates in the Lorentz space for the Stokes system,and the Lagrangian approach,we show that the 2-d MHd equations have a unique global solution.

关键词： inhomogeneous MHd equations electrical conductivity global unique solutions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Review on Security defense Technology Research in Edge Computing Environment

引用

Chinese Journal of Electronics 2024年第1期33卷 1-18页

作者： ke SHANG Weizhen HE Shuai ZHANG national digital Switching System Engineering and Technological R&d Center

Edge computing, which achieves quick data processing by sinking data computing and storage to the network edge, has grown rapidly along with the Internet of things. The new network architecture of edge computing brings new security challenges. Based on this, this paper investigates the edge computing security literature published in recent years and summarizes and analyzes research work on edge computing security from different attack surfaces. We start with the definition and architecture of edge computing. From the attack surface between device and edge server, as well as on edge servers, the research describes the security threats and defense methods of edge computing. In addition, the cause of the attack and the pros and cons of defense methods is introduced. The challenges and future research directions of edge computing are given.

关键词： Cloud computing Systems architecture Computer architecture Network architecture data processing Security Servers

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Love wave propagation in one-dimensional piezoelectric quasicrystal multilayered nanoplates with surface effects

引用

Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 619-632页

作者： Xin FENG Liaoliang ke Yang GAO College of Science China Agricultural UniversityBeijing 100083China School of Mechanical Engineering Tianjin UniversityTianjin 300350China

The exact solutions for the propagation of Love waves in one-dimensional(1d)hexagonal piezoelectric quasicrystal(PQC)nanoplates with surface effects are *** electro-elastic model is developed to investigate the anti-plane strain problem of Love wave *** introducing three shape functions,the wave equations and electric balance equations are decoupled into three uncorrelated *** the boundary conditions of the top surface on the covering layer,the interlayer interface,and the matrix,a dispersive equation with the influence of multi-physical field coupling is provided.A surface PQC model is developed to investigate the surface effects on the propagation behaviors of Love waves in quasicrystal(QC)multilayered structures with nanoscale thicknesses.A novel dispersion relation for the PQC structure is derived in an explicit closed form according to the non-classical mechanical and electric boundary *** examples are given to reveal the effects of the boundary conditions,stacking sequence,characteristic scale,and phason fluctuation characteristics on the dispersion curves of Love waves propagating in PQC nanoplates with surface effects.

关键词： piezoelectric quasicrystal(PQC)material multilayered plate dispersion characteristic surface effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Partial Collapsing degeneration of Floer Trajectories and Adiabatic Gluing

引用

Acta Mathematica Sinica,English Series 2024年第1期40卷 161-249页

作者： Yong-Geun OH ke ZHU Center for Geometry and Physics Institute for Basic Science(IBS)79 Jigok-ro 127beon-gilNam-guPohang-siGyeongsangbuk-doKorea 37673&POSTECHGyeongsangbuk doKorea department of Mathematics and Statistics Minnesota State UniversityMankatoMN 56001USA

In the present paper,we study partial collapsing degeneration of Hamiltonian-perturbed Floer trajectories for an adiabatic ε-family and its reversal adiabatic gluing,as the prototype of the partial collapsing degeneration of 2-dimensional(perturbed)J-holomorphic maps to 1-dimensional gradient *** consider the case when the Floer equations are S^(1)-invariant on parts of their domains whose adiabatic limit has positive length as ε→0,which we call thimble-flow-thimble *** main gluing theorem we prove also applies to the case with Lagrangian boundaries such as in the problem of recovering holomorphic disks out of pearly *** particular,our gluing theorem gives rise to a new direct proof of the chain isomorphism property between the Morse-Bott version of Lagrangian intersection Floer complex of L by Fukaya-Oh-Ohta-Ono and the pearly complex of L Lalonde and *** also provides another proof of the present authors’earlier proof of the isomorphism property of the PSS map without involving the target rescaling and the scale-dependent gluing.

关键词： Floer trajectory equation partial collapsing degeneration thimble-flow-thimble moduli space adiabatic gluing exponential decay estimates three-interval method

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Advances in ground heat exchangers for space heating and cooling:Review and perspectives

引用

Energy and Built Environment 2024年第2期5卷 255-269页

作者： Ping Cui Weibo Yang Wenke Zhang ke Zhu Jeffrey d.Spitler Mingzhi Yu School of Thermal Engineering Shandong Jianzhu UniversityJinanShandong 250101China College of Electrical Energy and Power EngineeringYangzhou UniversityYangzhouJiangsu 225127China department of Mechanical Engineering Oklahoma State UniversityStillwaterOKUSA

As a renewable energy source,geothermal energy has been widely used to provide space heating and cooling for *** thermal performance of ground heat exchanger(GHE)is significant for the operating efficiency of the ground source heat pump(GSHP)*** paper presents a comprehensive review of developments and advances of three kinds of GHE,including vertical borehole GHE(VBGHE),Pile GHE(PGHE),and deep borehole GHE(dBGHE)which are currently popular in larger GSHP ***,analytical models proposed to ana-lyze heat transfer process of VBGHE with different geological conditions are summarized,such as homogenous or heterogeneous ground,with or without groundwater *** and short-time step models and measures to improve GHE thermal performance are also ***,a summary of research advances in PGHE is provided,which includes the heat transfer models of PGHE,the effects of geometric structure,oper-ation modes,pile spacing,use of phase change material(PCM),thermal properties of PCM,thermo-mechanical behavior and/or thermal performance of *** effects of groundwater flow direction and velocity on PGHE are also summarized in ***,models of three kinds of dBGHEs,i.e.,deep coaxial GHE(dCGHE),deep U-bend GHE(dUGHE)and super-long gravity heat pipe(SLGHP),are *** physical bases of the dif-ferent analytical models are elaborated and also their advantages and disadvantages are *** in numerical modelling and improving numerical model calculation speed of dCBHE,dCBHE array,and dUBHE are *** review provides a meaningful reference for the further study of GHEs.

关键词： Vertical borehole ground heat exchanger Pile ground heat exchanger deep borehole ground heat exchanger Modelling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quantized bound states around a vortex in anisotropic superconductors

引用

Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 146-155页

作者： ke Xiang da Wang Qiang-Hua Wang national Laboratory of Solid State Microstructures&School of Physics Nanjing UniversityNanjing 210093China Collaborative Innovation Center of Advanced Microstructures Nanjing 210093China

The bound states around a vortex in anisotropic superconductors is a longstanding yet important *** this work,we develop a variational theory on the basis of the Andreev approximation to obtain the energy levels and wave functions of the low-energy quantized bound states in superconductors with anisotropic pairing on arbitrary Fermi *** the case of circular Fermi surface,the effective Schr¨odinger equation yielding the bound state energies gets back to the theory proposed by Volovik and Kopnin many years *** generalization here enables us to prove the equidistant energy spectrum inside a vortex in a broader class of *** importantly,we are now able to obtain the wave functions of these bound states by projecting the quasiclassical wave function on the eigenmodes of the effective Schr¨odinger equation,going beyond the quasiclassical Eilenberger results,which,as we find,are sensitive to the scattering *** the case of isotropic Fermi surface,the spatial profile of the low-energy local density of states is dominated near the vortex center and elongates along the gap antinode directions,in addition to the ubiquitous Friedel oscillation arising from the quantum inteference neglected in the Eilenberger ***,as a consequence of the pairing anisotropy,the quantized wave functions develop a peculiar distribution of winding number,which reduces stepwise towards the vortex *** work provides a flexible way to study the vortex bound states in the future.

关键词： vortex bound state anisotropic superconductor Andreev approximation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Neuropeptide Y receptor Y8b(npy8br)regulates feeding and digestion in Japanese medaka(Oryzias latipes)larvae:evidence from gene knockout

引用

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第7期25卷 605-616页

作者： Xiaodan JIA ke LU Xufang LIANG College of Fisheries Chinese Perch Research CenterHuazhong Agricultural UniversityWuhan 430070China Engineering Research Center of Green development for Conventional Aquatic Biological Industry in the Yangtze River Economic Belt Ministry of EducationWuhan 430070China

Neuropeptide Y receptor Y8(NPY8R)is a fish-specific receptor with two subtypes,NPY8AR and *** in expression levels during physiological processes or in vivo regulation after ventricular injection suggest that NPY8BR plays an important role in feeding regulation;this has been found in only a few fish,at *** order to better understand the physiological function of npy8br,especially in digestion,we used clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)technology to generate npy8br-/-japanese medaka(Oryzias latipes).We found that the deletion of npy8br in medaka larvae affected their feeding and digestion ability,ultimately affecting their ***,npy8br deficiency in medaka larvae resulted in decreased feed intake and decreased expression levels of orexigenic genes(npy and agrp).npy8br-/-medaka larvae fed for 10 d(10th day of feeding)still had incompletely digested brine shrimp(Artemia nauplii)in the digestive tract 8 h after feeding,the messenger Rna(mRna)expression levels of digestion-related genes(amy,lpl,ctra,and ctrb)were significantly decreased,and the activity of amylase,trypsin,and lipase also significantly *** deletion of npy8br in medaka larvae inhibited the growth and significantly decreased the expression of growth-related genes(gh and igf1).Hematoxylin and eosin(H&E)sections of intestinal tissue showed that npy8br-/-medaka larvae had damaged intestine,thinned intestinal wall,and shortened intestinal *** far,this is the first npy8br gene knockout model established in fish and the first demonstration that npy8br plays an important role in digestion.

关键词： Neuropeptide Y receptor Y8b(npy8br) Japanese medaka(Oryzias latipes) Knockout Feeding digestion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bayesian Filtering for High-dimensional State-Space Models With State Partition and Error Compensation

引用

IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1239-1249页

作者： ke Li Shunyi Zhao Biao Huang Fei Liu key Laboratory of Advanced Process Control for Light Industry(Ministry of Education) Institute of AutomationJiangnan UniversityWuxi 214122China department of Chemical and Materials Engineering University of AlbertaEdmonton AB T6G 2G6Canada

In the era of exponential growth of data availability,the architecture of systems has a trend toward high dimensionality,and directly exploiting holistic information for state inference is not always computationally *** paper proposes a novel Bayesian filtering algorithm that considers algorithmic computational cost and estimation accuracy for high-dimensional linear *** high-dimensional state vector is divided into several blocks to save computation resources by avoiding the calculation of error covariance with immense *** that,two sequential states are estimated simultaneously by introducing an auxiliary variable in the new probability space,mitigating the performance degradation caused by state ***,the computational cost and error covariance of the proposed algorithm are analyzed analytically to show its distinct features compared with several existing *** results illustrate that the proposed Bayesian filtering can maintain a higher estimation accuracy with reasonable computational cost when applied to high-dimensional linear systems.

关键词： filtering estimation error

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Two imprinted genes primed by dEMETER in the central cell and activated by WRKY10 in the endosperm

引用

Journal of Genetics and Genomics 2024年第8期51卷 855-865页

作者： ke Yang Yuling Tang Yue Li Wenbin Guo Zhengdao Hu Xuanpeng Wang Frédéric Berger Jing Li College of Life Science and Technology Huazhong Agricultural UniversityWuhanHubei 430070China Sanya Institute of Breeding and Multiplication Hainan UniversitySanyaHainan 572025China School of Tropical Agriculture and Forestry Hainan UniversityHaikouHainan 570228China Hainan Yazhou Bay Seed Laboratory SanyaHainan 572025China Gregor Mendel Institute Austrian Academy of SciencesVienna BioCenter1030 ViennaAustria

The early development of the endosperm is crucial for balancing the allocation of maternal nutrients to *** process is believed to be evolutionarily associated with genomic imprinting,resulting in parentally biased allelic gene *** Fertilization Independent Seed(FIS)genes,the number of imprinted genes involved in early endosperm development and seed size determination remains *** study introduces early endosperm-expressed HAIKU(IKU)downstream Candidate F-box 1(ICF1)and ICF2 as maternally expressed imprinted genes(MEGs)in Arabidopsis *** these genes are also demethylated by dEMETER(dME)in the central cell,their activation differs from the direct dME-mediated activation seen in classical MEGs such as the FIS ***,ICF maternal alleles carry pre-established hypomethylation in their promoters,priming them for activation by the WRKY10 transcription factor in the *** the contrary,paternal alleles are predominantly suppressed by CG ***,we find that ICF genes partially contribute to the small seed size observed in iku *** discovery reveals a two-step regulatory mechanism that highlights the important role of conventional transcription factors in the activation of imprinted genes,which was previously not fully ***,the mechanism provides a new dimension to understand the transcriptional regulation of imprinting in plant reproduction and development.

关键词： Imprinting Epigenetics dnamethylation Seedsize Endosperm

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：