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Public transport inclusion and active aging: A systematic review on elderly mobility

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Journal of Traffic and Transportation Engineering(English Edition) 2024年第2期11卷 312-347页

作者： na Zhang Qi Yang School of Humanities Chang'an UniversityXi'an 710064China School of Transportation Engineering Chang'an UniversityXi'an 710064China School of Economics and Management Chang'an UniversityXi'an 710064China

Global aging has brought attention to addressing the elderly mobility dilemma,and a commitment to address inclusive transport in *** inclusion for older adults aims at establishing an age-friendly transport *** a direct policy goal and promoting active aging as an indirect social goal,to help older populations gain access to transport and social *** on the analysis of scientific knowledge mapping over the past 30 years,this study visualizes the hotspots and trends in elderly mobility *** a qualitative analysis of 138 papers,this paper reviews the theoretical foundations for transport inclusion and three themes of elderly mobility research,proposes a framework for public transport(PT)inclusion research as well as future research *** study suggests that transport inclusion can help enhance elderly health,social participation,and subjective *** can improve their travel opportunities for active aging in four ways:opportunity accessibility,physical accessibility,age-friendly informationalization,and cost *** research should pay attention to examining the mechanism of perceived transport inclusion on active aging,expanding the multilevel research space of the capability approach(CA),and exploring the subjectiveobjective integrated research model for PT *** research contributes to the overall knowledge of the theoretical and empirical researches on PT inclusion for the elderly and promotes the integrated application of interdisciplinary knowledge in the field.

关键词： Transportation engineering Elderly mobility Transport-related social exclusion Transport inclusion Active aging

大学教学数字化:离心型与向心型模式比较——以澳大利亚麦考瑞大学和丹麦奥伦堡大学为例

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清华大学教育研究 2023年第3期44卷 45-53页

作者：周娜李辉信阳师范大学教育科学学院河南信阳464000 上海师范大学学前教育学院上海200234

数智时代的大学必须重视数字化建设,数字化建设的关键是教学数字化。澳大利亚麦考瑞大学和丹麦奥尔堡大学是国际上教学数字化建设的成功案例,各自开拓出“离心型”和“向心型”大学数字化建设路径。两所大学数字化都以教学数字化为突破... 详细信息

数智时代的大学必须重视数字化建设,数字化建设的关键是教学数字化。澳大利亚麦考瑞大学和丹麦奥尔堡大学是国际上教学数字化建设的成功案例,各自开拓出“离心型”和“向心型”大学数字化建设路径。两所大学数字化都以教学数字化为突破口,带动大学治理、社会服务等教育全要素数字化。但在技术路径上,两所大学表现出不同的数字化模式。大学数字化有多种路径,教学数字化是先导,以引领教育数字化,不同大学应根据学校特色,因时因地,走出自己的数字化之路。

关键词：教学数字化教育数字化麦考瑞大学奥尔堡大学

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基于模糊神经网络的广东省台风灾害损失预测

海洋环境科学 2022年第3期41卷 461-466页

作者：周纳刘强中国海洋大学工程学院山东青岛266100

台风灾害是我国最严重的海洋灾害之一,研究提高台风灾害损失预测的准确度对防灾减灾具有重要意义。针对目前机器学习算法在处理小样本数据时预测精度不高的问题,提出结合模糊数学的BP神经网络算法对台风灾害损失进行预测。本文选用广东... 详细信息

台风灾害是我国最严重的海洋灾害之一,研究提高台风灾害损失预测的准确度对防灾减灾具有重要意义。针对目前机器学习算法在处理小样本数据时预测精度不高的问题,提出结合模糊数学的BP神经网络算法对台风灾害损失进行预测。本文选用广东省2005-2016年记录较为完善的25个台风样本数据进行实验,首先利用信息扩散技术对初始数据进行正态信息扩散,再结合BP神经网络对台风灾害损失进行预测。结果表明,该方法能较好地解决台风灾害实测样本少和存在矛盾样本的问题,提高了台风灾害损失预测的精度。

关键词：信息扩散 BP神经网络台风灾害预测

Whole-cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for rapid identification of bacteria cultured in liquid media

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Science China(Life Sciences) 2011年第1期54卷 48-53页

作者： zhou na WANG na XU Bin WANG Jie FANG JunJian DONG FangTing HE Kun YANG XiaoHong Pharmaceutical Department of Jilin University Changchun 130021 China national Center of Biomedical Analysis Beijing 100850 China

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been used for many years to rapidly identify whole bacteria. However, no consistent methodology exists for the rapid identification of bacteria cultured in liquid media. Thus, in this study we explored the use of MALDI-TOF MS analysis for rapid identification of cells cultured in liquid media. We determined that 2,5-dihydroxybenzoic acid (50 mg mL-1, 50% acetonitrile, 0.1% trifluoroacetic acid) was the best matrix solution for MALDI-TOF MS for this type of study. Moreover, the tested strains were successfully differentiated by principal component analysis, and the main characteristics of the mass peaks for each species were found in mixed culture samples. In addition, we found that the minimum number of cells for detection was 1.8×103. In conclusion, our findings suggest that MS-based techniques can be developed as an auxiliary method for rapidly and accurately identifying bacteria cultured in liquid media.

关键词：基质辅助激光解吸细菌培养飞行质谱快速鉴定全细胞液体介质时间电离

Construction of CDKN2A-related competitive endogenous Rna network and identification of GAS5 as a prognostic indicator for hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1514-1531页

作者： Yong Pan Yi-Ru Zhang Ling-Yun Wang Li-na Wu Ying-Qiu Ma zhou Fang Shi-Bo Li Department of Infectious Disease Zhoushan HospitalWenzhou Medical UniversityZhoushan 316021Zhejiang ProvinceChina State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases The First Affiliated Hospital of Zhejiang UniversityHangzhou 310003Zhejiang ProvinceChina Department of Infectious Disease The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325035Zhejiang ProvinceChina

BACKGROUND Competitive endogenous Rna(ceRna)is an innovative way of gene expression modulation,which plays a crucial part in ***,the intricacy and behavioral characteristics of the ceRna network in hepatocellular carcinoma(HCC)remain *** To establish a cyclin dependent kinase inhibitor 2A(CDKN2A)-related ceRna network and recognize potential prognostic indicators for *** The mutation landscape of CDKN2A in HCC was first explored using the cBioPortal *** expression analysis was implemented between CDKN2Ahigh and CDKN2Alow expression HCC *** targeted microRnas were predicted by lncBasev3.0,and the targeted mRnas were predicted by miRDB,and Targetscan *** univariate and multivariate analysis were utilized to identify independent prognostic *** CDKN2A was frequently mutated and deleted in *** single-cell Rna-sequencing analysis revealed that CDKN2A participated in cell cycle *** CDKN2A-related ceRna network-growth arrest specific 5(GAS5)/miR-25-3p/SRY-box transcription factor 11(SOX11)was successfully ***5 was recognized as an independent prognostic biomarker,whose overexpression was correlated with a poor prognosis in HCC *** association between GAS5 expression and methylation,immune infilt-ration was ***,traditional Chinese medicine effective components targeting GAS5 were *** This CDKN2A-related ceRna network provides innovative insights into the molecular mechanism of HCC formation and ***,GAS5 might be a significant prognostic biomarker and therapeutic target in HCC.

关键词： Hepatocellular carcinoma Competitive endogenous Rna Molecular mechanism Prognosis Biomarker

Cooling Efficiency of Laminar Cooling System for Plate Mill

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Journal of Iron and Steel Research(International) 2008年第5期15卷 24-28页

作者： ZHANG Dian-hua WANG Bing-xing zhou na YU Ming WANG Jun State Key Laboratory of Rolling and Automation Northeastern University Shenyang 110004 Liaoning China

Heat transfer was researched from a perspective of the industry application. On the basis of the first law of thermodynamics, the cooling efficiency was deduced from the change of enthalpy inside hot plate. The relationship between the cooling efficiency and its influencing parameters was regressed from plenty of data collected from the worksite and discussed in detail. The temperature profiles resulting from the online model and the model modified by regressed formulas were presented and compared. The results indicated that the control accuracy of the modified model was increased obviously.

关键词： hot rolled plate laminar cooling cooling efficiency temperature profile

氨氯地平贝那普利片(Ⅱ)治疗原发性高血压的疗效及安全性分析

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中国基层医药 2024年第5期31卷 691-695页

作者：张敏周娜刘修凤喻群群陈光平解美玲刘梅花杨祥陈亚丽首钢水钢医院心内科六盘水553000 首钢水钢医院病案科六盘水553000 首钢水钢医院护理部六盘水553000

目的观察氨氯地平贝那普利片(Ⅱ)治疗原发性高血压的临床疗效和安全性。方法选择2022年6月至2023年6月在首钢水钢医院接受诊治的原发性高血压患者280例为研究对象,采用临床病例对照研究方法,按照返回随机数(RAND)函数法随机分为四组,并... 详细信息

目的观察氨氯地平贝那普利片(Ⅱ)治疗原发性高血压的临床疗效和安全性。方法选择2022年6月至2023年6月在首钢水钢医院接受诊治的原发性高血压患者280例为研究对象,采用临床病例对照研究方法,按照返回随机数(RAND)函数法随机分为四组,并接受不同治疗方法,分别是氨氯地平组(A组,70例)、贝那普利组(B组,70例)、单片复方制剂氨氯地平贝那普利片(Ⅱ)组(C组,71例)、氨氯地平+贝那普利组(D组,69例)。观察相关疗效指标(血压达标率、血压值变化)和安全性指标(不良反应、服药依从性)。结果C组和D组血压达标率分别为91.5%(65/71)和89.9%(62/69),两组差异无统计学意义(χ^(2)=1.24,P=0.143),但均高于A组和B组的77.1%(54/70)和74.3%(52/70)(χ^(2)=5.68、4.86,P=0.004、0.012)。治疗前,四组患者的收缩压和舒张压差异均无统计学意义(均P>0.05);治疗后,四组患者的收缩压和舒张压较治疗前均明显下降(均P0.05),治疗后舒张压低于D组(t=6.01,P<0.05)。四组患者治疗后总胆固醇、三酰甘油和低密度脂蛋白胆固醇均呈现降低趋势(均P<0.05)。B组和D组治疗后分别出现15例和10例干咳患者,较A组和C组(1例和3例)显著增加(χ^(2)=4.25、5.04,均P<0.05)。A组、B组和C组的治疗依从性分别是72.9%(51/70)、71.4%(50/70)、74.6%(53/71),均高于D组的46.4%(32/69)(χ^(2)=4.68、5.24、4.98,均P<0.05)。结论复方制剂氨氯地平贝那普利(Ⅱ)治疗原发性高血压的临床疗效和安全性优于单片药物及两药联用。

关键词：高血压血压测定药物相关性副作用和不良反应服药依从性氨氯地平疗效比较研究

SERS devices with "hedgehog-like" nanosphere arrays for detection of trace pesticides

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Journal of Innovative Optical Health Sciences 2021年第4期4卷 72-81页

作者： Yang Liu Xin Li Jie Cheng na zhou Lingqian Zhang Haiyang Mao Chengjun Huang Institute of Microelectronics of Chinese Academy of Sciences Beijing 100029P.R.China University of Chinese Academy of Sciences Beijing 100049P.R.China Wuxi Internet of Things Innovation Center Co.Ltd.Advanced Sensing Department Wuxi 214001P.R.China

The development of surface-enhanced Raman scattering(SERS)devices for detection of trace pesticides has attracted more and more *** this work,a large-area self-assembly ap-proach assisted with reactive ion etching(RIE)is proposed for preparing SERS devices consisting of Ag-covered"hedgehog-like"nanosphere arrays(Ag/HLnas).Such a SERS device has an enhancement factor of 2.79×107,a limit of detection(LOD)up to 10-12 M for Rhodamine 6G(R6G)analytes,and a relative standard deviation(RSD)smaller than 10%,demonstrating high ***,for pesticide detections,the device achieves an LOD of 10-s M for thiram *** indicates that the proposed SERS device has a promising opportunity in detecting toxic organic pesticides.

关键词： surface-enhanced Raman scattering(SERS) self-assembly Ag-covered"hedgehog-like"nanosphere arrays(Ag/HLnas) pesticide detections

Renal failure and hepatitis following ingestion of raw grass carp gallbladder:A case report

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World Journal of Clinical Cases 2021年第4期9卷 943-950页

作者： Li-na zhou Shao-Shao Dong Sheng-Ze Zhang Wen Huang Department of Nephrology Wenzhou People's HospitalWenzhou 325000Zhejiang ProvinceChina Department of Nephrology The Second Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina

BACKGROUND Fish gallbladder has long been used as a folk remedy in Asian *** organ damage after ingestion of fish gallbladder resulting in near mortality has been known to ***,we describe a case of acute renal failure(ARF)and hepatitis due to grass carp gallbladder poisoning and review the *** SUMMARY A previously healthy,50-year-old woman was admitted to our hospital with a 2-d history of generalized abdominal pain and repeated vomiting following ingestion of two raw grass carp gallbladders in an attempt to alleviate her *** developed anuria on day 4 with markedly elevated serum creatinine,urea,bilirubin,alanine aminotransferase,and aspartate *** on thorough evaluation of her history and prompt biochemical investigations,we diagnosed her with ARF and hepatitis secondary to fish gallbladder *** renal biopsy revealed acute tubular necrosis,following which she underwent six sessions of conventional hemodialysis due to renal *** treatment with gastric mucosal protectant and liver protectant was administered for targeted organ *** patient’s liver function gradually recovered,and serum creatinine was 164 mmol/L at discharge on day *** a follow-up period of 2 wk,her renal function completely *** Physicians should be mindful of toxic complications of raw grass carp gallbladder ingestion and we should promote awareness to reduce incidences of food poisoning.

关键词： Grass carp gallbladder Case report Acute renal failure Hepatitis Ichthyogallotoxin Hemodialysis