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Enabling highly efficient and broadband electromagnetic wave absorption by tuning impedance match in high-entropy transition metal diborides (HETMB_(2))

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Journal of Advanced Ceramics 2021年第6期10卷 1299-1316页

作者： Weiming ZHANG Fu-Zhi DAI Huimin XIANG Biao ZHAO Xiaohui WANG na ni Rajamallu KARRE Shijiang WU Yanchun ZHOU Science and Technology on Advanced Functional Composite Laboratory Aerospace Research Institute of Materials&Processing TechnologyBeijing 100076China Henan Key Laboratory of Aeronautical Materials and Application Technology School of Material Science and EngineeringZhengzhou University of AeronauticsZhengzhou 450046China Shenyang national Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Key Lab of Education Ministry for Power Machinery and Engineering School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China Zibo Firststar New Material Incorporated Co. Ltd.Zibo 255000China

The advance in communication technology has triggered worldwide concern on electromagnetic wave pollution.To cope with this challenge,exploring high-performance electromagnetic(EM)wave absorbing materials with dielectric and magnetic losses coupling is urgently required.Of the EM wave absorbers,transition metal diborides(TMB2)possess excellent dielectric loss capability.However,akin to other single dielectric materials,poor impedance match leads to inferior performance.High-entropy engineering is expected to be effective in tailoring the balance between dielectric and magnetic losses through compositional design.Herein,three HE TMB2 powders with nominal equimolar TM including HE TMB2-I(TM=Zr,Hf,Nb,Ta),HE TMB2-2(TM=Ti,Zr,Hf,Nb,Ta),and HE TMB2-3(TM=Cr,Zr,Hf,Nb,Ta)have been designed and prepared by one-step boro/carbothermal reduction.As a result of synergistic effects of strong attenuation capability and impedance match,HE TMB2-1 shows much improved performance with the optimal minimum reflection loss(RL_(min))of-59.6 dB(8.48 GHz,2.68 mm)and effective absorption bandwidth(EAB)of 7.6 GHz(2.3 mm).Most impressively,incorporating Cr in HE TMB2-3 greatly improves the impedance match over 1-18 GHz,thus achieving the RLmin of-56.2 dB(8.48 GHz,2.63 mm)and the EAB of 11.0 GHz(2.2 mm),which is superior to most other EM wave absorbing materials.This work reveals that constructing high-entropy compounds,especially by incorporating magnetic elements,is effectual in tailoring the impedance match for highly conductive compounds,i.e.,tuning electrical conductivity and boosting magnetic loss to realize highly efficient and broadband EM wave absorption with dielectric and magnetic coupling in single-phase materials.

关键词： transition metal diboride(TMB2) high-entropy(HE)ceramics electronic structure microwave absorption dielectric and magnetic losses coupling

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Endoscopic full-thickness resection to treat active Dieulafoy's disease: A case report

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World Journal of Gastroenterology 2020年第30期26卷 4557-4563页

作者： Shan Yu Xiao-Ming Wang Xin Chen Hong-Yan Xu Guang-Jie Wang na ni Yu-Xin Sun Department of Gastroenterology Panzhihua Central HospitalPanzhihua 617067Sichuan ProvinceChina

BACKGROUND At present,minimally invasive endoscopic treatment is mostly used for patients with actively bleeding Dieulafoy’s lesions,,as it has the advantages of minimal trauma,short operation time and good hemostatic effect,although bleeding can easily recur postoperatively.Recently,extensive gastric cuneiform resection has been advocated for use in these patients because the constant-diameter artery follows a long path to the gastric mucosa.CASE SUMMARY A 47-year-old man was admitted to the hospital for repeated hematemesis and black stool,and he was diagnosed with Dieulafoy’s disease.We chose a method that not only simulates surgical gastric cuneiform resection but also reduces trauma.We performed enlarged local endoscopic full-thickness resection of the gastric wall and abdominal constant-diameter artery and sutured the gastric wall.Postoperative follow-up showed that the constant-diameter artery had been resected from the gastric wall,which was confirmed to have no blood flow signals by endoscopic ultrasonography.CONCLUSION Endoscopic full-thickness resection of the gastric wall and abdominal constantdiameter artery with suturing of the gastric wall has demonstrated potential as a new treatment for Dieulafoy's disease.

关键词： Dieulafoy’s disease Endoscopic full-thickness resection Ultrasound gastroscopy Case report

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火焰法与喷雾干燥法共合成固体氧化物燃料电池阴极La0.6Sr0.4CoO3–δ–Ce0.8Gd0.2O2–δ的微观结构与性能分析

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硅酸盐学报 2024年第6期52卷 1810-1819页

作者：王天齐相龙凯高展张毅然倪娜屠恒勇朱磊黄震上海交通大学国家电投智慧能源创新学院上海交通大学机械与动力工程学院

实现阴极结构的纳米化以提升电极三相界面长度，是提升固体氧化物燃料电池（SOFC）性能的有效途径。基于火焰喷雾热解法和喷雾干燥法，分别一步法合成纳米级和亚微米级的La0.6Sr0.4CoO3–δ–Ce0.8Gd0.2O2–δ复相材料。将2种粒径范围... 详细信息

实现阴极结构的纳米化以提升电极三相界面长度，是提升固体氧化物燃料电池（SOFC）性能的有效途径。基于火焰喷雾热解法和喷雾干燥法，分别一步法合成纳米级和亚微米级的La0.6Sr0.4CoO3–δ–Ce0.8Gd0.2O2–δ复相材料。将2种粒径范围材料按照不同质量比混合，制成氧化钇部分稳定氧化锆电解质支撑的固体氧化物燃料电池的阴极，并系统分析电池性能与结构特征。结果表明，喷雾干燥合成材料与火焰喷雾热解合成材料的质量比为70:30时，SOFC电化学性能最优，850℃时最大功率密度为0.47 W/cm2，面电阻为0.62?·cm2，相应的欧姆阻抗和极化阻抗为0.36?·cm2和0.26?·cm2。实验证明，混合不同粒径颗粒制成的SOFC阴极，可有效构建电子–离子导通网络，并形成更多的三相界面和反应活性位点，从而获得较好的电化学性能。本研究为固体氧化物燃料电池阴极材料微观结构和性能优化提供了新的思路。

关键词：固体氧化物燃料电池火焰喷雾热解法喷雾干燥法阴极弛豫时间分布法

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Removal of laparoscopic cerclage stitches via laparotomy and rivanol-induced labour: A case report and literature review

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World Journal of Clinical Cases 2022年第1期10卷 304-308页

作者： Xin-ni na Ben-Shuo Cai Department of Obstetrics and Gynecology Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

BACKGROUND Laparoscopic cervical cerclage is performed for patients with abnormal cervical anatomy and/or transvaginal cervical cerclage failure.However,the method of removing the stitches to allow labour induction remains controversial.According to published literature,stitches are removed through laparoscopic or transvaginal methods.Herein,we report,for the first time,a case of a patient who had undergone laparoscopic cerclage,and then underwent removal of stitches by laparotomy and labour induction in the third trimester of pregnancy.CASE SUMMARY A patient who underwent laparoscopic cervical cerclage due to cervical insufficiency became pregnant naturally following the operation.At 31 wk of pregnancy,severe foetal malformations were found.To successfully induce labour,cerclage stitches were removed via laparotomy,and rivanol was injected directly into the uterus.Following successful induction of labour,the patient delivered a dead foetus.CONCLUSION This report provides a reliable scheme of removing cerclage stitches for patients who have undergone laparoscopic cerclage but experience severe foetal malformations.

关键词： Laparoscopic cerclage Pregnancy Induced labour Stitch removal Case report

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Giant tumor resection under ultrasound-guided nerve block in a patient with severe asthma:A case report

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World Journal of Clinical Cases 2022年第10期10卷 3200-3205页

作者： Qian Liu Qing Zhong ni-na Zhou Ling Ye Department of Pain Management West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Anesthesiology The People's Hospital of Jianyang CityJianyang 610041Sichuan ProvinceChina Department of Anesthesiology Zigong First People’s HospitalZigong 643000Sichuan ProvinceChina

BACKGROUND General anesthesia in critically ill patients is associated with increased risk of complications.Nerve block anesthesia is an alternative,but could be challenging in cases with surgical field that involves multiple dermatomes.CASE SUMMARY We report resection of a giant lipoma in the left shoulder and upper back under supraclavicular brachial plexus block plus T3-4 paravertebral block in an older patient with severe asthma.A 70-year-old patient presented with a slow-growing giant mass(25,15 and 5 cm in length,width and depth,respectively)that extended from the lateral side of the left scapula to the axillary midline,and from the T5 thoracic vertebra intercostal to the mid-medial section of the left upper arm.He had sharp intermittent pain over the mass for the past 7 d.The patient also had severe bronchial asthma for the past 8 years.A pulmonary function test revealed only 20%of the predicted forced expiratory volume in 1 second(FEV1,0.49 L).After controlling asthma with glucocorticoid,the tumor was resected under ultrasound-guided supraclavicular brachial plexus block and T3-4 paravertebral block.The surgery was completed without incident.CONCLUSION Ultrasound-guided regional nerve block is a viable alternative for patients with poor cardiopulmonary function undergoing shoulder,back and axillary surgery.

关键词： Ultrasound Giant tumor Brachial plexus block Paravertebral block Case report

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阿卡波糖联合瑞舒伐他汀治疗糖尿病合并高脂血症的效果及对糖脂代谢、氧化应激反应的影响

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临床医学研究与实践 2024年第16期9卷 96-99页

作者：倪娜魏素滨雷烨陕西省勉县医院陕西汉中724200 长武县人民医院陕西咸阳713600 陕西中医药大学第二附属医院陕西咸阳712000

目的探讨阿卡波糖联合瑞舒伐他汀治疗糖尿病合并高脂血症的效果及对糖脂代谢、氧化应激反应的影响。方法选取2020年5月至2022年5月收治的120例糖尿病合并高脂血症患者为研究对象,采用随机数字表法将其分为对照组与观察组,各60例。对照... 详细信息

目的探讨阿卡波糖联合瑞舒伐他汀治疗糖尿病合并高脂血症的效果及对糖脂代谢、氧化应激反应的影响。方法选取2020年5月至2022年5月收治的120例糖尿病合并高脂血症患者为研究对象,采用随机数字表法将其分为对照组与观察组,各60例。对照组给予二甲双胍+瑞舒伐他汀治疗,观察组给予阿卡波糖+瑞舒伐他汀治疗。比较两组的治疗效果。结果治疗后,观察组的糖化血红蛋白(HbA1c)、空腹血糖(FPG)、三酰甘油(TG)及氧化型低密度脂蛋白(ox-LDL)水平低于对照组(P<0.05)。治疗后,观察组的丙二醛(MDA)、8-异前列腺素F2α(8-iso-PGF2α)水平低于对照组,谷胱甘肽过氧化物酶(GSH-Px)水平高于对照组(P<0.05)。治疗后,观察组的内皮素(ET)水平及循环内皮细胞(CEC)低于对照组,一氧化氮(NO)水平高于对照组(P<0.05)。结论阿卡波糖联合瑞舒伐他汀治疗糖尿病合并高脂血症可有效调节患者的糖脂代谢水平,减轻氧化应激反应损伤,对血管内皮功能起到保护作用,值得临床推广。

关键词：阿卡波糖瑞舒伐他汀糖尿病高脂血症糖脂代谢氧化应激反应

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Ferroptosis as a novel form of regulated cell death:Implications in the pathogenesis,oncometabolism and treatment of human cancer

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Genes & Diseases 2022年第2期9卷 347-357页

作者： Feifei Pu Fengxia Chen Zhicai Zhang Deyao Shi Binlong Zhong Xiao Lv Andrew Blake Tucker Jiaming Fan Alexander J.Li Kevin Qin Daniel Hu Connie Chen Hao Wang Fang He na ni Linjuan Huang Qing Liu William Wagstaff Hue H.Luu Rex C.Haydon Le Shen Tong-Chuan He Jianxiang Liu Zengwu Shao Department of Orthopedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022PR China Department of Radiation and Medical Oncology Zhongnan HospitalWuhan UniversityWuhanHubei 430071PR China Hubei Cancer Clinical Study Center Zhongnan HospitalWuhan UniversityWuhanHubei 430071PR China Department of Orthopaedic Surgery Johns Hopkins UniversityBaltimoreMD 21205USA Molecular Oncology Laboratory Department of Orthopaedic Surgery and Rehabilitation MedicineThe University of Chicago Medical CenterChicagoIL 60637USA Ministry of Education Key Laboratory of Diagnostic Medicine Department of Clinical BiochemistrySchool of Laboratory MedicineChongqing Medical UniversityChongqing 400016PR China Departments of Nephrology and Obstetrics and GynecologyThe First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016PR China Department of Spine Surgery Second Xiangya HospitalCentral South UniversityChangshaHunan 410011PR China Department of Surgery The University of Chicago Medical CenterChicagoIL 60637USA

The treatment of cancer mainly involves surgical excision supplemented by radiotherapy and chemotherapy.Chemotherapy drugs act by interfering with tumor growth and inducing the death of cancer cells.Anti-tumor drugs were developed to induce apoptosis,but some patient’s show apoptosis escape and chemotherapy resistance.Therefore,other forms of cell death that can overcome the resistance of tumor cells are important in the context of cancer treatment.Ferroptosis is a newly discovered iron-dependent,non-apoptotic type of cell death that is highly negatively correlated with cancer development.Ferroptosis is mainly caused by the abnormal increase in iron-dependent lipid reactive oxygen species and the imbalance of redox homeostasis.This review summarizes the progression and regulatory mechanism of ferroptosis in cancer and discusses its possible clinical applications in cancer diagnosis and treatment.

关键词： Cancer Cancer therapy Clinical application Ferroptosis Lipid peroxidation Pathogenesis

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Reversibly immortalized keratinocytes(iKera)facilitate re-epithelization and skin wound healing:Potential applications in cell-based skin tissue engineering

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Bioactive Materials 2022年第3期7卷 523-540页

作者： Jiamin Zhong Hao Wang Ke Yang Huifeng Wang Chongwen Duan na ni Liqin An Yetao Luo Piao Zhao Yannian Gou Shiyan Sheng Deyao Shi Connie Chen William Wagstaff b Bryce Hendren-Santiago b Rex C.Haydon b Hue H.Luu b Russell R.Reid Sherwin HHo Guillermo A.Ameer Le Shen Tong-Chuan He Jiaming Fan Ministry of Education Key Laboratory of Diagnostic Medicine And Department of Clinical BiochemistrySchool of Laboratory MedicineChongqing Medical UniversityChongqing400016China Molecular Oncology Laboratory Department of Orthopaedic Surgery and Rehabilitation MedicineThe University of Chicago Medical CenterChicagoIL60637USA The Pediatric Research Institute The Children’s Hospital of Chongqing Medical UniversityChongqing400014China Biomedical Engineering Department Northwestern UniversityEvanstonIL60208USA Department of Orthopaedics Union Hospital of Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Department of Surgery The University of Chicago Medical CenterChicagoIL60637USA Center for Advanced Regenerative Engineering(CARE) EvanstonIL60208USA Department of Surgery Northwestern University Feinberg School of MedicineChicagoIL60616USA

Skin injury is repaired through a multi-phase wound healing process of tissue granulation and re-epithelialization.Any failure in the healing process may lead to chronic non-healing wounds or abnormal scar formation.Although significant progress has been made in developing novel scaffolds and/or cell-based therapeutic strategies to promote wound healing,effective management of large chronic skin wounds remains a clinical challenge.Keratinocytes are critical to re-epithelialization and wound healing.Here,we investigated whether exogenous keratinocytes,in combination with a citrate-based scaffold,enhanced skin wound healing.We first established reversibly immortalized mouse keratinocytes(iKera),and confirmed that the iKera cells expressed keratinocyte markers,and were responsive to UVB treatment,and were non-tumorigenic.In a proof-of-principle experiment,we demonstrated that iKera cells embedded in citrate-based scaffold PPCN provided more effective re-epithelialization and cutaneous wound healing than that of either PPCN or iKera cells alone,in a mouse skin wound model.Thus,these results demonstrate that iKera cells may serve as a valuable skin epithelial source when,combining with appropriate biocompatible scaffolds,to investigate cutaneous wound healing and skin regeneration.

关键词： Keratinocytes Skin tissue engineering Reversible immortalization SV40 large T antigen PPCN Skin wound healing

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自噬在毛发再生中的作用

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中国组织工程研究 2024年第7期28卷 1112-1117页

作者：黄雨馨梁文姿陈秀文倪娜赵颖琳林常敏汕头大学医学院广东省汕头市515041 汕头大学精神卫生中心广东省汕头市515065

背景:在生物医学界,自噬是一个快速发展的研究热点,许多研究人员正在积极探究多种疾病中自噬的分子调控机制,但是自噬在毛发生长中所起的作用仍存在许多未知。目的:综述目前自噬在毛发生长与再生中的研究进展及应用价值,了解自噬在毛发... 详细信息

背景:在生物医学界,自噬是一个快速发展的研究热点,许多研究人员正在积极探究多种疾病中自噬的分子调控机制,但是自噬在毛发生长中所起的作用仍存在许多未知。目的:综述目前自噬在毛发生长与再生中的研究进展及应用价值,了解自噬在毛发生长中的作用,以探究自噬在病理性脱发中的发病机制,为研究治疗脱发的药物提供新思路。方法:应用计算机在中国知网(CNKI)、PubMed数据库中,以“毛囊生长,毛发生长,毛发再生,自噬相关蛋白,自噬活性,自噬相关基因,自噬”或“hair growth,hair follicle,hair regeneration,autophagy”为检索词进行检索。查阅国内外近年来关于自噬、毛发生长和自噬在毛发生长中作用的研究进展进行总结,排除与文章主题内容不相符的文献,最终纳入78篇文献进行结果分析。结果与结论:(1)自噬是真核生物的正常代谢过程,具有复杂的分子机制和功能特性,既有利于细胞生存,又可促进细胞死亡。(2)脱发相关疾病与自噬活性的改变有关,且自噬活性可调控毛发生长周期;敲除或过表达自噬相关基因可改变毛发生长状态,已发现有多条自噬相关信号通路与毛囊生长有关;自噬的激活剂或抑制剂可用于治疗或预防脱发疾病。

关键词：毛囊毛发毛发再生毛囊再生毛囊生长周期自噬自噬活性自噬激活剂自噬抑制剂

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^(18)F-FDGPET/CT对偶发性进展期结直肠腺瘤的诊断价值

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中国临床医学影像杂志 2024年第6期35卷 423-427页

作者：徐妮娜彭雨诗唐栋戚正伟丁建平唐坤杭州师范大学附属医院放射科浙江杭州310000 温州医科大学附属第一医院核医学科浙江温州325000 浙江大学医学院附属邵逸夫医院消化内科浙江杭州310000

目的:^(18)F-FDGPET/CT最大标准摄取值(SUVmax)与进展期结直肠腺瘤的关系尚不明确。本研究旨在探讨^(18)F-FDGPET/CT的SUVmax鉴别进展期及非进展期结直肠腺瘤的能力。方法:回顾性分析153例经^(18)F-FDGPET/CT偶然发现的结直肠腺瘤患者... 详细信息

目的:^(18)F-FDGPET/CT最大标准摄取值(SUVmax)与进展期结直肠腺瘤的关系尚不明确。本研究旨在探讨^(18)F-FDGPET/CT的SUVmax鉴别进展期及非进展期结直肠腺瘤的能力。方法:回顾性分析153例经^(18)F-FDGPET/CT偶然发现的结直肠腺瘤患者的资料,根据癌化风险分为进展期和非进展期结直肠腺瘤两组。术前PET/CT测量病灶的SUVmax,采用受试者工作特性(ROC)曲线分析确定两组的最佳截断值。纳人常规的临床特征,采用Logistic回归模型进行单因素和多因素分析确定独立危险因素。结果:进展期和非进展期两组结直肠腺瘤患者的SUVmax分别为8.61±4.01、5.02±2.00,差异有统计学意义(P<0.05),Logistic多因素回归分析显示SUVmax、CEA、CA125和隐血是预测进展期结直肠腺瘤的独立危险因素。单SUVmax检测的曲线下面积(AUC)为0.810,SUVmax联合CEA、CA125及隐血检测的AUC为0.879。结论:基于^(18)F-FDGPET/CT成像的SUVmax是预测进展期结直肠腺瘤的独立危险因素,可以作为一种无创的定量诊断工具,有助于术前指导治疗策略的制定。

关键词：结直肠肿瘤正电子发射断层显像计算机体层摄影术氟脱氧葡萄糖F18

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