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Gorgan Bay： a microcosm for study on macrobenthos speciesenvironment relationships in the southeastern Caspian Sea

Acta Oceanologica Sinica 2016年第4期35卷 82-88页

作者： GHASEmI Amir Faraz TAHERI mehrshad FOSHTOmI maryam Yazdani noranian m.jid mIRA Seyed Sahab JAm Armin Iranian National Institute for Oceanography and Atmospheric Science (INIOAS) Tehran *** Iran Department of the Environment Golestan Province Gorgan *** Iran

The relationship between spatial patterns of macrobenthos community characteristics and environmental conditions（salinity, temperature, dissolved oxygen, organic matter content, sand, silt and clay） was investigated throughout the Gorgan Bay in June 2010. Principal components analysis（PCA） based on environmental data separated eastern and western stations. The maximum（4 500 ind./m2） and minimum（411 ind./m2） densities were observed at Stas 1 and 6, respectively. Polychaeta was the major group and Streblospio gynobranchiata was dominant species in the bay. According to Distance Based Linear models results, macrofaunal total density was correlated with silt percentage and salinity and these two factors explaining 64% of the variability while macrofaunal community structure just correlated with salinity（22% total variation）. In general, western part of the bay showed the highest number of species and biodiversity while, the highest density was found at Sta. 1 and in the middle part of the bay. Furthermore, relationship between diversity indices and macrobenthic species with measured factors is also discussed. Our results confirm the effect of salinity as an important factor on distribution of macrobenthic fauna in south Caspian brackish waters.

关键词： salinity macrobenthos species-environment relationship Gorgan Bay Caspian Sea

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Biofabrication of nanocomposite-based scaffolds containing human bone extracellularmatrix for the differentiation of skeletal stem and progenitor cells

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Bio-Design and manufacturing 2024年第2期7卷 121-136页

作者： Yang-Hee Kim Janos m.Kanczler Stuart Lanham Andrew Rawlings marta Roldo Gianluca Tozzi Jonathan I.Dawson Gianluca Cidonio Richard O.C.Oreffo Faculty of medicine Bone and Joint Research GroupCentre for Human DevelopmentStem Cells and RegenerationInstitute of Developmental SciencesUniversity of SouthamptonSouthampton SO166YDUK School of Pharmacy and Biomedical Science University of PortsmouthPortsmouth PO12DTUK School of Engineering Faculty of Engineering and ScienceUniversity of GreenwichGreenwich ME44TBUK Center for Life Nano-and Neuro-Science(CLN2S) Italian Institute of Technology00161 RomeItaly

Autograft or metal implants are routinely used in skeletal ***,they fail to provide long-term clinical resolution,necessitating a functional biomimetic tissue engineering *** use of native human bone tissue for synthesizing a biomimeticmaterial inkfor three-dimensional(3D)bioprintingof skeletal tissueis anattractivestrategyfor ***,human bone extracellular matrix(bone-ECm)offers an exciting potential for the development of an appropriate microenvironment for human bone marrow stromal cells(HBmSCs)to proliferate and differentiate along the osteogenic *** this study,we engineered a novel material ink(LAB)by blending human bone-ECm(B)with nanoclay(L,Laponite®)and alginate(A)polymers using extrusion-based *** inclusion of the nanoﬁller and polymeric material increased the rheology,printability,and drug retention properties and,critically,the preservation of HBmSCs viability upon *** composite of human bone-ECm-based 3D constructs containing vascular endothelial growth factor(VEGF)enhanced vascularization after implantation in an ex vivo chick chorioallantoic membrane(CAm)*** inclusion of bone morphogenetic protein-2(BmP-2)with the HBmSCs further enhanced vascularization and mineralization after only seven *** study demonstrates the synergistic combination of nanoclay with biomimetic materials(alginate and bone-ECm)to support the formation of osteogenic tissue both in vitro and ex vivo and offers a promising novel 3D bioprinting approach to personalized skeletal tissue repair.

关键词： Extracellular matrix Nanoclay Bone 3D bioprinting

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