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Assessment of cardiac function and synchronicity in subjects with isolated bundle branch block using Doppler imaging

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Chinese Medical Journal 2006年第10期119卷 795-800页

作者： niu hong-xia hua wei zhang shu sun xin wang fang-zheng chen ke-ping wang Hao chen xin Centre of Arrhythmia Diagnosis and Treatment Fuwai Hospital and Cardiovascular Institute Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China Department of Echocardiography Fuwai Hospital and Cardiovascular Institute Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China

Background Using tissue Doppler imaging and conventional echocardiographic technique, we examined the cardiac function and synchronicity in individuals with isolated right bundle branch block （RBBB） or left bundle b... 详细信息

关键词： bundle branch block synchronicity cardiac function tissue Doppler imaging

Short-term effect of cardiac resynchronization therapy in patients with ischaemic or nonischaemic cardiomyopathy

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Chinese Medical Journal 2006年第18期119卷 1507-1510页

作者： hua wei niu hong-xia wang fang-zheng zhang shu chen ke-ping chen xin Department of Clinical Electrophysiology Fuwai Hospital and Cardiovascular Institute Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100037 China

Background Patients with heart failure were candidates for cardiac resynchronization therapy （CRT） regardless of underlying aetiology. This study observed the effect of CRT in patients with ischaemic or nonischaemic cardiomyopathy. Methods One hundred and forty-two patients with refractory chronic heart failure and left bundle branch block received cardiac resynchronization therapy, 91 men and 51 women, average age 60 years. Left ventricular ejection fraction （LVEF） was severely depressed （mean 29%）, left ventricular end diastolic diameter （LVEDD） enlarged （mean 72 mm） and QRS width was lengthened （mean 147 ms）. Ninety-eight had nonischaemic cardiomyopathy and 44 had ischaemic cardiomyopathy. Results After cardiac resynchronization therapy, the heart function was significantly improved. The mean LVEF increased from 29% to 36% after pacing. In patients with nonischaemic cardiomyopathy, the LVEF was improved from 28% to 37%, and in patients with ischaemic cardiomyopathy, the LVEF was improved from 30% to 36%. No significant difference of the improvement was found between the two groups （P〉0.05）. Conclusions Cardiac resynchronization therapy could significantly improve cardiac function in patients with chronic heart failure regardless of the underlying heart disease.

关键词： cardiac resynchronization therapy cardiomyopathy, ischaemic nonischaemic

Complications of cardiac resynchronization therapy in patients with congestive heart failure

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Chinese Medical Journal 2006年第6期119卷 449-453页

作者： niu hong-xia hua wei wang fang-zheng zhang shu chen ke-ping chen xin Centre of Arrhythmia Diagnosis and Treatment Fuwai HospitalChinese Academy of Medical Sciences and Peking Union MedicalCollege Beijing 100037 China

Background Previous clinical studies have suggested that patients with congestive heart failure and intraventricular conduction delay could benefit from cardiac resynchronization therapy （CRT）. Implantation of left ventricular lead is a complex procedure with some potential for complications. This study was conducted to analyse the complications of CRT in patients with congestive heart failure.Methods Totally 117 patients, 86 males and 31 females, mean age of 53 years, with congestive heart failure and intraventricular conduction delaywere enrolled in this study. Venography was performed on all patients. Different types of coronary sinus leads were used to pace the left ventricle.Results Left ventricular lead was attempted to implant through coronary sinus for all the 117 patients and was successfully implanted in 111 patients. The success rate was 94.9%. Main complications rate was 6.8%, including coronary sinus dissection in 4 patients, phrenic nerve stimulation required lead repositioning in 2 patients and lead dislodgement in 2 patients.Conclusions It is feasible and safe to pace left ventricle through coronary sinus. However, there are some procedural complications.

关键词： cardiac resynchronization therapy congestive heart failure compfication

Chromosome-scale assembly of the Dendrobium chrysotoxum genome enhances the understanding of orchid evolution

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Horticulture Research 2021年第1期8卷 2684-2697页

作者： Yongxia zhang Guo-Qiang zhang Diyang zhang Xue-Die Liu xin-Yu Xu wei-hong sun xia Yu xiaoen Zhu Zhi-Wen wang xiang Zhao Wen-Ying Zhong hongfeng chen wei-Lun Yin Tengbo huang Shan-Ce niu Zhong-Jian Liu Guangdong Provincial key Laboratory for Plant Epigenetics College of Life Sciences and OceanographyShenzhen UniversityShenzhen 518071China Laboratory for Orchid Conservation and Utilization Orchid Conservation and Research CenterThe National Orchid Conservation CenterShenzhen 518114China School of Food Science and Technology Foshan UniversityFoshan 528225China key Laboratory of National Forestry and Grassland Administration for Orchid Conservation and Utilization at College of Landscape Architecture Fujian Agriculture and Forestry UniversityFuzhou 350002China College of Forestry Fujian Agriculture and Forestry UniversityFuzhou 350002China PubBio-Tech Wuhan 430070China key Laboratory of Plant Resources Conservation Sustainable Utilization South China Botanical GardenChinese Academy of SciencesGuangzhou 510650China College of Biological Sciences and Technology Beijing Forestry UniversityBeijing 100083China College of Horticulture Hebei Agricultural UniversityBaoding 071000China

As one of the largest families of angiosperms,the Orchidaceae family is *** represents the second largest genus of the ***,an assembled high-quality genome of species in this genus is ***,we report a chromosome-scale reference genome of Dendrobium chrysotoxum,an important ornamental and medicinal orchid *** assembled genome size of *** was 1.37 Gb,with a contig N50 value of 1.54 *** the sequences,95.75%were anchored to 19 *** were 30,044 genes predicted in the *** *** whole-genome polyploidization events occurred in *** terms of the second event,whole-genome duplication(WGD)was also found to have occurred in other Orchidaceae members,which diverged mainly via gene loss immediately after the WGD event occurred;the first duplication was found to have occurred in most monocots(tau event).We identified sugar transporter(SWEET)gene family expansion,which might be related to the abundant medicinal compounds and fleshy stems of ***-box genes were identified in ***,as well as members of TPS and Hsp90 gene families,which are associated with resistance,which may contribute to the adaptive evolution of *** also investigated the interplay among carotenoid,ABA,and ethylene biosynthesis in *** to elucidate the regulatory mechanisms of the short flowering period of orchids with yellow *** reference *** genome will provide important insights for further research on medicinal active ingredients and breeding and enhances the understanding of orchid evolution.

关键词： evolution flowers breeding

Advances in nuclear detection and readout techniques

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Nuclear Science and Techniques 2023年第12期34卷 281-358页

作者： Rui He xiao‑Yang niu Yi wang hong‑wei Liang hong‑Bang Liu Ye Tian hong‑Lin zhang Chao‑Jie Zou Zhi‑Yi Liu Yun‑Long zhang Hai‑Bo Yang Ju huang hong‑Kai wang wei‑Jia Han Bei Cao Gang chen Cong Dai Li‑Min Duan Rui‑Rui Fan fang‑Fa Fu Jian‑hua Guo Dong Han wei Jiang xian‑Qin Li xin Li Zhuo‑Dai Li Yu‑Tie Liang shun Liao De‑Xu Lin cheng‑Ming Liu Guo‑Rui Liu Jun‑Tao Liu Ze Long Meng‑chen niu Hao Qiu Hu Ran xiang‑Ming sun Bo‑Tan wang Jia wang Jin‑xiang wang Qi‑Lin wang Yong‑Sheng wang xiao‑Chuan xia Hao‑Qing Xie He‑Run Yang hong Yin hong Yuan Chun‑Hui zhang Rui‑Guang Zhao Ran zheng cheng‑xin Zhao Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Advanced Energy Science and Technology Guangdong Laboratory Huizhou 516000China key Laboratory of Particle and Radiation Imaging Department of Engineering PhysicsTsinghua UniversityBeijing 100084China School of Integrated Circuits Dalian University of TechnologyDalian 116020China Guangxi key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China State key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Electronic Engineering School Heilongjiang UniversityHarbin 150080China Spallation Neutron Source Science Center Dongguan 523803China Micro‑electronic Department Harbin Institute of TechnologyHarbin 150001China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210034China Liaoning Academy of Materials Shenyang 110167China Istituto Nazionale di Fisica Nucleare Sezione di PerugiaPerugiaItaly School of Mathematics and Physics Chengdu University of TechnologyChengdu 620035China PLAC Key Laboratory of Quark and Lepton Physics(MOE)Central China Normal UniversityWuhan 430079China School of Electronics and Information Northwestern Polytechnical UniversityXi’an 710129China State key Lab of Superhard Materials College of PhysicsJilin UniversityChangchun 130012China School of Computer Science Northwestern Polytechnical UniversityXi’an 710129China

“A Craftsman Must Sharpen His Tools to Do His Job,”said *** detection and readout techniques are the foundation of particle physics,nuclear physics,and particle astrophysics to reveal the nature of the ***,they are being increasingly used in other disciplines like nuclear power generation,life sciences,environmental sciences,medical sciences,*** article reviews the short history,recent development,and trend of nuclear detection and readout techniques,covering Semiconductor Detector,Gaseous Detector,Scintillation Detector,Cherenkov Detector,Transition Radiation Detector,and Readout *** explaining the principle and using examples,we hope to help the interested reader underst and this research field and bring exciting information to the community.

关键词： Silicon detector Wide bandgap detector Time projection chamber(TPC) Multigap resistive plate chamber detector(MRPC) Scintillation detector Calorimeters Cherenkov detector Transition radiation detector Artificial intelligence Trigger-less readout

Significant loss of soil inorganic carbon at the continental scale

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National Science Review 2022年第2期9卷 13-20页

作者： xiao-Dong Song Fei Yang hua-Yong Wu Jing zhang De-cheng Li Feng Liu Yu-Guo Zhao Jin-Ling Yang Bing Ju Chong-Fa Cai Biao huang huai-Yu Long Ying Lu Yue-Yu Sui Qiu-Bing wang ke-Ning Wu Feng-Rong zhang Ming-Kui zhang Zhou Shi Wan-Zhu Ma Gang xin Zhi-ping Qi Qing-Rui Chang En Ci Da-Gang Yuan Yang-Zhu zhang Jun-ping Bai Jia-Ying chen Jie chen Yin-Jun chen Yun-Zhong Dong Chun-Lan Han Ling Li Li-Ming Liu Jian-Jun Pan Fu-Peng Song Fu-Jun sun Deng-Feng wang Tian-wei wang xiang-hua wei hong-Qi Wu xia Zhao Qing Zhou Gan-Lin zhang State key Laboratory of Soil and Sustainable Agriculture Institute of Soil Science Chinese Academy of Sciences College of Advanced Agricultural Sciences University of Chinese Academy of Sciences College of Resources and Environment Huazhong Agricultural University Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences College of Natural Resources and Environment South China Agricultural University Northeast Institute of Geography and Agroecology Chinese Academy of Sciences College of Land and Environment Shenyang Agricultural University School of Land Science and Technology China University of Geosciences College of Land Science and Technology China Agricultural University College of Environmental and Resource Sciences Zhejiang University Institute of Digital Agriculture Zhejiang Academy of Agricultural Sciences College of Agriculture Heilongjiang Bayi Agricultural University Tropical Crops Genetic Resources Institute Chinese Academy of Tropical Agricultural Sciences College of Natural Resources and Environment Northwest A & F University College of Resources and Environment Southwest University College of Resources Sichuan Agricultural University College of Resources and Environment Hunan Agricultural University Institute of Agricultural Product Quality Standard and Testing Research Tibet Academy of Agricultural and Animal Husbandry Sciences School of Agricultural Sciences Zhengzhou University Institute of Agriculture Environment and Resources Research Shanxi Academy of Agricultural Sciences College of Resources and Environment Henan Agricultural University College of Resources and Environment China Agricultural University College of Resources and Environmental Sciences Nanjing Agricultural University College of Resources and Environment Shandong Agricultural University Agricultural College Guangxi University College of Grassland and Environment Science Xinjiang Agricultural University College of Geographical Science Qinghai Normal University

Widespread soil acidification due to atmospheric acid deposition and agricultural fertilization may greatly accelerate soil carbonate dissolution and ***,to date,few studies have addressed these ***,we use meta-analysis and nationwide-survey datasets to investigate changes in soil inorganic carbon(SIC) stocks in *** observe an overall decrease in SIC stocks in topsoil(0-30 cm)(11.33 g C m-2yr-1) from the 1980 s to the 2010 *** SIC stocks have decreased by～8.99±2.24%(1.37±0.37 Pg C).The average SIC losses across China(0.046 Pg C yr-1) and in cropland(0.016 Pg C yr-1) account for～17.6%-24.0% of the terrestrial C sink and 57.1% of the soil organic carbon sink in cropland,*** deposition and climate change have profound influences on SIC *** estimate that～19.12%-19.47% of SIC stocks will be further lost by *** consumption of SIC may offset a large portion of global efforts aimed at ecosystem carbon sequestration,which emphasizes the importance of achieving a better understanding of the indirect coupling mechanisms of nitrogen and carbon cycling and of effective countermeasures to minimize SIC loss.

关键词： China soil inorganic carbon stocks global change carbonate soil acidification

心脏再同步化治疗除颤器在慢性心力衰竭患者中的临床应用

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中华心血管病杂志 2007年第12期35卷 1096-1098页

作者：华伟张澍王方正丁立刚牛红霞陈柯萍陈新中国医学科学院北京协和医学院阜外心血管病医院心律失常诊治中心 100037

目的总结具有心脏再同步化治疗(CRT)和埋藏式自动复律除颤器(ICD)功能的心脏再同步化治疗除颤器(CRT-D)用于临床治疗慢性心力衰竭(心衰)的初步经验。方法 17例药物治疗无效的慢性心衰患者接受了 CRT-D 治疗,其中6例患者接受了具有心衰... 详细信息

目的总结具有心脏再同步化治疗(CRT)和埋藏式自动复律除颤器(ICD)功能的心脏再同步化治疗除颤器(CRT-D)用于临床治疗慢性心力衰竭(心衰)的初步经验。方法 17例药物治疗无效的慢性心衰患者接受了 CRT-D 治疗,其中6例患者接受了具有心衰预警功能的 InSync Sentry。基础病因为扩张性心肌病12例,缺血性心肌病5例;13例患者既往有室性心动过速或心室颤动的发作病史。结果 17例患者均成功置入 CRT-D,左室导线平均起搏阈值为1.6 V,除颤阈值≤20 J,无并发症发生。平均随访13个月,5例患者发生室性心动过速诱发的电击除颤。1例置入 InSync Sentry的患者由于心功能恶化出现2次心衰报警事件,药物治疗后好转。结论 CRT-D 置入手术相对安全,不仅能改善患者心功能,而且可预防心脏性猝死的发生。

关键词：心力衰竭充血性起搏器人工除颤器植入型

Prevalence and clinical characteristics of autoimmune liver disease in hospitalized patients with cirrhosis and acute decompensation in China

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World Journal of Gastroenterology 2022年第31期28卷 4417-4430页

作者： Zi-Xuan Shen Dan-Dan Wu Jie xia xian-Bo wang xin zheng Yan huang Bei-Ling Li Zhong-Ji Meng Yan-Hang Gao Zhi-ping Qian Feng Liu xiao-Bo Lu Jia Shang hua-Dong Yan Yu-Bao zheng Wen-Yi Gu Yan zhang Jian-Yi wei Wen-Ting Tan Yi-xin Hou Qun zhang Yan Xiong Cong-Cong Zou Jun chen Ze-Bing huang Xiu-hua Jiang Sen Luo Yuan-Yuan chen Na Gao Chun-Yan Liu wei Yuan Xue Mei Jing Li Tao Li xin-Yi Zhou Guo-hong Deng Jin-Jun chen Xiong Ma Hai Li Department of Gastroenterology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Shanghai Institute of Digestive Disease Key Laboratory of Gastroenterology and HepatologyChinese Ministry of HealthShanghai Jiao Tong UniversityShanghai 200001China Department of Infectious Diseases Southwest HospitalThe Third Military Medical University(Army Medical University)Chongqing 400038China Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100102China Department of Infectious Diseases Institute of Infection and ImmunologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022Hubei ProvinceChina Department of Infectious Diseases Hunan Key Laboratory of Viral HepatitisXiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina Hepatology Unit Department of Infectious DiseasesNanfang HospitalSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of Infectious Disease Taihe HospitalHubei University of MedicineShiyan 430418Hubei ProvinceChina Department of Hepatology The First Hospital of Jilin UniversityChangchun 130031Jilin ProvinceChina Department of Liver Intensive Care Unit Shanghai Public Health Clinical CentreFudan UniversityShanghai 201508China Tianjin Institute of Hepatology Nankai University Second People’s HospitalTianjin 300102China Department of Infectious Diseases and Hepatology The Second Hospital of Shandong UniversityJinan 250033Shandong ProvinceChina Infectious Disease Center The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi 830054XinjiangChina Department of Infectious Diseases Henan Provincial People’s HospitalZhengzhou 450003Henan ProvinceChina Department of Infectious Diseases Hwamei HospitalThe Second Hospital of NingboUniversity of Chinese Academy of SciencesNingbo 315153Zhejiang ProvinceChina Department of Infectious Diseases The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 5

BACKGROUND Autoimmune liver disease(AILD)has been considered a relatively uncommon disease in China,epidemiological data for AILD in patients with cirrhosis and acute decompensation(AD)is *** To investigate the prevalence,outcome and risk factors for AILD in cirrhotic patients complicated with AD in *** We collected data from patients with cirrhosis and AD from two prospective,multicenter cohorts in hepatitis B virus endemic *** were regularly followed up at the end of 28-d,90-d and 365-d,or until death or liver transplantation(LT).The primary outcome in this study was 90-d LTfree ***-on-chronic liver failure(ACLF)was assessed on admission and during 28-d hospitalization,according to the diagnostic criteria of the European Association for the Study of the Liver(EASL).Risk factors for death were analyzed with logistic regression *** In patients with cirrhosis and AD,the overall prevalence of AILD was 9.3%(242/2597).Prevalence of ACLF was significantly lower in AILD cases(14%)than those with all etiology groups with cirrhosis and AD(22.8%)(P<0.001).Among 242 enrolled AILD patients,the prevalence rates of primary biliary cirrhosis(PBC),autoimmune hepatitis(AIH)and PBC-AIH overlap syndrome(PBC/AIH)were 50.8%,28.5%and 12.0%,*** ACLF patients,the proportions of PBC,AIH and PBC/AIH were 41.2%,29.4% and 20.6%.28-d and 90-d mortality were 43.8% and 80.0% in AILD-related *** etiology of AILD had no significant impact on 28-d,90-d or 365-d LTfree mortality in patients with cirrhosis and AD in both univariate and multivariate *** bilirubin(TB),hepatic encephalopathy(HE)and blood urea nitrogen(BUN)were independent risk factors for 90-d LT-free mortality in multivariate *** development of ACLF during hospitalization only independently correlated to TB and international normalized *** AILD was not rare in hospitalized patients with cirrhosis and AD in China,among which PBC was the m

关键词： Prevalence Autoimmune liver disease Cirrhosis and acute decompensation Mortality Acuteon-chronic liver failure

The Cymbidium genome reveals the evolution of unique morphological traits

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Horticulture Research 2021年第1期8卷 3449-3463页

作者： Ye Ai Zhen Li wei-hong sun Juan chen Diyang zhang Liang Ma Qing-hua zhang Ming-Kun chen Qing-Dong zheng Jiang-Feng Liu Yu-Ting Jiang Bai-Jun Li Xuedie Liu xin-Yu Xu xia Yu Yu zheng xing-Yu Liao Zhuang Zhou Jie-Yu wang Zhi-Wen wang Tai-xiang Xie Shan-Hu Ma Jie Zhou Yu-Jie ke Yu-Zhen Zhou Hsiang-Chia Lu ke-wei Liu Feng-Xi Yang Gen-Fa Zhu Laiqiang huang Dong-Hui Peng Shi-Pin chen Siren Lan Yves Van de Peer Zhong-Jian Liu key Laboratory of National Forestry and Grassland Administration for Orchid Conservation and Utilization at College of Landscape Architecture Fujian Agriculture and Forestry UniversityFuzhouChina Department of Plant Biotechnology and Bioinfor matics Ghent UniversityGentBelgium VIB Center for Plant Systems Biology GentBelgium College of Forestry Fujian Agriculture and Forestry UniversityFuzhouChina Management Office of Yushan Scenic Area FuzhouChina College of Agriculture and Biotechnology Zhejiang UniversityHangzhouChina key Laboratory of Plant Resource Conservation and Sustainable Utilization South China Botanical GardenChinese Academy of SciencesGuangzhouChina PubBio-Tech WuhanChina Tsinghua-Berkeley Shenzhen Institute(TBSI) Center for Biotechnology and Biomedicine and Shenzhen Key Laboratory of Gene and Antibody The rapyState Key Laboratory of Chemical OncogenomicsState Key Laboratory of Health Sciences and TechnologyInstitute of Biopha rmaceutical and Health Engineering(iBHE)Shenzhen International Graduate SchoolTsinghua UniversityShenzhenChina Guangdong key Laboratory of Ornamental Plant Germplasm Innovation and Utilization Environmental Horticulture Research InstituteGuangdong Academy of Agricultural SciencesGuangzhouChina Department of Biochemistry Genetics and MicrobiologyUniversity of PretoriaPretoriaSouth Africa College of Horticulture Academy for Advanced Interdisciplinary StudiesNanjing Agricultural UniversityNanjingChina Henry Fok College of Biology and Agriculture Shaoguan UniversityShaoguanChina Institute of Vegetable and Flowers Shandong Academy of Agricultural SciencesJinanChina

The marvelously diverse Orchidaceae constitutes the largest family of *** genus Cymbidium in Orchidaceae is well known for its unique vegetation,floral morphology,and flower scent ***,a chromosomescale assembly of the genome of Cymbidium ensifolium(Jianlan)is *** genomic analysis showed that *** has experienced two whole-genome duplication(WGD)events,the most recent of which was shared by all orchids,while the older event was the t event shared by most *** results of MADS-box genes analysis provided support for establishing a unique gene model of orchid flower development regulation,and flower shape mutations in *** were shown to be associated with the abnormal expression of MADS-box *** most abundant floral scent components identi fied included methyl jasmonate,acacia alcohol and linalool,and the genes involved in the floral scent component network of *** were ***,the decreased expression of photosynthesis-antennae and photosynthesis metabolic pathway genes in leaves was shown to result in colorful striped leaves,while the increased expression of MADS-box genes in leaves led to perianth-like *** results provide fundamental insights into orchid evolution and diversi fication.

关键词： traits evolution establishing