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人工智能在麻醉学专业硕士临床技能培训考核中的应用可行性探讨

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医学教育研究与实践 2019年第3期27卷 421-425页

作者：易斌陈芋文钟坤华甯交琳鲁开智张炬顾健腾陆军军医大学第一附属医院手术麻醉科重庆400038 中国科学院重庆绿色智能技术研究院重庆400714

人工智能(artificial intelligence,AI)作为新的技术科学,可以依据"多源临床教学数据的实时采集与辨识""面向人工智能方法的教学指标分析与预测预警模型的构建""教学评测评估算法与智能教学干预提示"等多种关键技术,对麻醉学专业硕士生... 详细信息

人工智能(artificial intelligence,AI)作为新的技术科学,可以依据"多源临床教学数据的实时采集与辨识""面向人工智能方法的教学指标分析与预测预警模型的构建""教学评测评估算法与智能教学干预提示"等多种关键技术,对麻醉学专业硕士生临床技能操作和术中麻醉管理数据进行实时分析采集,同时融合手术患者HIS/PACS/EMR临床数据以及追踪随访数据,由此形成高质量临床技能培训教学大数据集;并智能分析数据集与专硕生操作技能、评估评测、反馈以及患者预后等关联,构建临床技能培训评估评测反馈人工智能支持知识图谱,实现对专硕生培训期间技能培训质量的实时追踪,能够有效对专硕生临床技能的弱项以及不足等自动诊断和综合追踪预警;能够减少大量临床技能培训对带教导师工作量的依赖度,切实提高每位麻醉学专业硕士研究生的临床培训质量,在此方面具有较佳的应用前景。

关键词：麻醉学人工智能临床培训

未来网络产业:技术演进、大国竞争与发展路径

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改革 2025年第1期 81-92页

作者：渠慎宁中国社会科学院工业经济研究所新兴产业研究室中国社会科学院国家经济发展与经济风险研究中心

以6G与卫星互联网为代表的未来网络产业不仅是未来产业发展的重点领域,而且是网络强国建设的重要保障。经历了从1G到5G的技术演进后,6G作为下一代移动通信主导技术,不仅具有更高的性能指标,还将开启“万物智联”新时代。卫星互联网作为... 详细信息

以6G与卫星互联网为代表的未来网络产业不仅是未来产业发展的重点领域,而且是网络强国建设的重要保障。经历了从1G到5G的技术演进后,6G作为下一代移动通信主导技术,不仅具有更高的性能指标,还将开启“万物智联”新时代。卫星互联网作为卫星通信的最新演进载体,已被视为提供大规模数据传输服务的新手段,有望解决现有通信网络的瓶颈问题。未来网络产业具有巨大的产业空间和市场潜力,6G不仅能打造“新型感知经济”,还将通过数字孪生赋能实体经济,卫星互联网的商业与国防军事价值正日益凸显。当前,世界主要大国均意识到未来网络技术对经济、社会、国家安全乃至国际地位的重要影响,纷纷加紧布局力求抢占技术高点与竞争先机。我国应加大重视力度,增加未来网络领域的研发投入,着力构建未来网络的行业标准,打造安全可控的未来网络产业链,加快未来网络产业的应用落地和场景推广,以此快速推进未来网络产业发展。

关键词：未来产业未来网络 6G 卫星互联网数字孪生

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Unveiling solid-solid contact states in all-solid-state lithium batteries:An electrochemical impedance spectroscopy viewpoint

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Journal of Energy Chemistry 2025年第2期101卷 16-22页

作者： Jin-Liang Li Liang Shen Zi-ning Cheng Jun-Dong Zhang ling-Xuan Li Yu-Tong Zhang Yan-Bin Gao Chunli Guo Xiang Chen Chen-Zi Zhao Rui Zhang Qiang Zhang Tsinghua Center for Green Chemical Engineering Electrification Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical Engineering Tsinghua University College of Materials Science and Engineering Taiyuan University of Technology Advanced Research Institute of Multidisciplinary Science School of Materials Science and Engineering Beijing Institute of Technology Beijing Huairou Laboratory Institute for Carbon Neutrality Tsinghua University Shanxi Research Institute for Clean Energy Tsinghua University

All-solid-state lithium batteries（ASSLBs） are strongly considered as the next-generation energy storage devices for their high energy density and intrinsic *** solid-solid contact between lithium metal and solid electrolyte plays a vital role in the performance of working ASSLBs,which is challenging to investigate quantitatively by experimental *** work proposed a quantitative model based on the finite element method for electrochemical impedance spectroscopy simulation of different solid-solid contact states in *** the assistance of an equivalent circuit model and distribution of relaxation times,it is discovered that as the number of voids and the sharpness of cracks increase,the contact resistance Rcgrows and ultimately dominates the battery *** accurate fitting,inverse proportional relations between contact resistance Rcand（1-porosity） as well as crack angle was *** contribution affords a fresh insight into clarifying solid-solid contact states in ASSLBs.

关键词： All-solid-state lithium batteries Distribution of relaxation times Electrochemical impedance spectroscopy Equivalent circuit model Finite element method Solid-solid contacts

Organic Synthesis through Radical Innovation:Frustrated Radical Pairs

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Chinese Journal of Chemistry 2024年第10期42卷 1157-1160页

作者： Zhibin Hu Zengrui Cheng ning jiao State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Shanghai Key Laboratory of Green Chemistry and Chemical Processes East China Normal UniversityShanghai 200062China

Frustrated Lewis Pairs(FLPs)represent a unique class of interactions in Lewis acid-base chemistry,driven by spatial hindrance or incongruent orbital energy levels that hinder the formation of effective coordination *** have received significant attention for their application in activating small molecules and facilitating organic synthesis *** developments have led to the emergence of Frustrated Radical Pairs(FRPs)as an extension of the radical *** are formed from FLPs through Single Electron Transfer(SET)and exhibit the ability to activate a variety of chemical *** research on FLPs is well-established,investigations into FRPs in organic reactions remain *** review highlights the current state of FRPs in organic synthesis,delves into mechanistic insights,explores their potential,and underscores the challenges in this emerging field.

关键词： Radicals Frustrated Lewis Pairs Frustrated Radical Pairs Methodology and reactions Reaction mechanisms

Phase transition thermosensitive photocatalytic hydrogel for enhanced uranium extraction

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Science Bulletin 2025年第1期70卷 4-6页

作者： Jiacheng Zhang Yihui Yuan ning Wang State Key Laboratory of Marine Resource Utilization in South China Sea Collaborative Innovation Center of Marine Science and TechnologyHainan UniversityHaikou 570228China

As a clean energy source,nuclear energy is crucial for realizing carbon neutralization and the construction of many nuclear plants is underway[1].According to an estimate by the International Atomic Energy Agency,the global nuclear energy production is expected to increase by 56%between 2015 and 2030[2].However,with current consumption rate of uranium resources,terrestrial uranium reserves will be depleted within approximately 80 years[3,4].

关键词： approximate transition hydrogel

DHA and EPA protect against cognitive impairment induced by chronic sleep deprivation through regulating iron-mitophagy homeostasis

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Food Science and Human Wellness 2025年

作者： Lu Chen Yueqi Yang ning Zhang Bin Sun Hongxia Che Zhengping Wang Jun Han Min Wen Institute of Biopharmaceutical Research， Liaocheng University College of Marine Science and Biological Engineering， Qingdao University of Science and Technology Pet Nutrition R research and Development Center Gambol Pet Group Co.，Ltd.

The cognitive impairments resulting from insufficient sleep have emerged as a significant public health concern in contemporary society， lacking effective treatments due to the absence of elucidation regarding its molecular mechanism. This study aimed to investigate the efficacy of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) against cognitive deficits in a mouse model of chronic sleep deprivation (CSD)， and to elucidate the underlying mechanisms. CSD mice display significant cognitive deficits in the Morris water maze task with obviously neuronal damage. We observed that dysregulation of iron transport proteins (IRP1， TfR1， DMT1， and FPN1) in CSD mice resulted in iron deposition in the cortex. Subsequent assessment revealed upregulation of mitophagy and neuronal lipid peroxidation and downregulation of proteins in the mitochondrial respiratory chain complexes (I-V). Further molecular analysis revealed inhibition of the Sirt3-Nrf2 pathway and its downstream antioxidant molecules (e.g. GPX4， HO-1， SOD2， and NQO1). In contrast， dietary supplementation with DHA or EPA alleviated CSD-induced cognitive impairment by inhibiting neuronal ferroptosis through regulating iron-mitophagy homeostasis. Notably， EPA showed superior efficiency in ameliorating cognitive impairment， potentially due to its stronger interaction with Sirt3 compared to DHA.

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Super-self-assembly extraction from natural herbs

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Nano Research 2025年第2期18卷 367-376页

作者： Jiawei Xiang Yuan Meng Mingyuan Zhao Zhongxian Li Qiang Zhang ning Wang Zhuo Ao Dong Han CAS Center for Excellence in Nanoscience National Center for Nanoscience and TechnologyBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Hebei Key Lab of Nano-biotechnology Hebei Key Lab of Applied ChemistryYanshan UniversityQinhuangdao 066004China Guang’anmen Hospital of the China Academy of Chinese Medical Sciences Beijing 100053China

Life systems are complex systems,and the self-assembly behaviour represents the transition from disorder to order and serves as a concrete indicator and starting point for understanding complex ***-self-assembly behaviour was observed in the decoctions of various natural herbs,and this behaviour was characterized by multistep and multilevel assembly *** super-self-assemblies were multilevel particles resulting from inorganic-organic assembly,specifically observed ascomposite spheres,cubes,and tetragonal *** preparation process was environmentally friendly and safe,and the resulting super-self-assemblies were regular in shape and rich in variety;this process has numerous possibilities for development and application in medicine and materials research.

关键词： self-assembly natural herbs multi-morphological particles complex system

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不同比例尺铁路桥箱梁风洞试验涡振对比

铁道工程学报 2025年第1期42卷 64-68,76页

作者：王骑黄林高贵李世文宁伯伟西南交通大学成都610031 风工程四川省重点实验室成都610031 武九铁路客运专线湖北有限责任公司武汉430201 中铁大桥勘测设计院集团有限公司武汉430050

研究目的:整体式钝体钢箱梁作为大跨度铁路桥近年来采用的一种主梁形式,涡激振动现象较为显著,为研究比例尺对铁路桥钝体箱梁节段模型涡振试验的影响,采用1∶90、1∶50与1∶25节段模型风洞试验,对比不同比例尺试验下铁路桥钝体箱梁断面... 详细信息

研究目的:整体式钝体钢箱梁作为大跨度铁路桥近年来采用的一种主梁形式,涡激振动现象较为显著,为研究比例尺对铁路桥钝体箱梁节段模型涡振试验的影响,采用1∶90、1∶50与1∶25节段模型风洞试验,对比不同比例尺试验下铁路桥钝体箱梁断面的涡振响应,在此基础上分析研究铁路桥钝体箱梁节段模型风洞试验的适宜缩尺比。研究结论:(1)铁路桥钝体箱梁的涡激振动试验结果受模型比例尺影响较大,其中1∶50节段模型试验中获得的断面涡振响应最为显著,通过1∶25比例尺试验获得的断面涡振响应较小,但该两种比例尺模型的主要涡振特性试验结果大致吻合;(2)1∶90节段模型试验在各风攻角下均没有测试到断面的涡振响应,采用小尺度模型试验无法有效反映钝体箱梁铁路桥实桥的涡振特性;(3)在不考虑节段模型系统满足与实桥间质量与质量惯性矩相似律的条件下,可以在小尺度(1∶90比例尺)模型试验中获得铁路桥钝体箱梁断面的涡激振动,虽无法借此判定实际铁路桥梁的涡振响应,但可借此对比断面涡振性能的高低,在主梁设计阶段初期辅助完成气动优化措施的研究;(4)本研究成果可为大跨度铁路桥箱梁的风洞试验比例尺设定提供参考。

关键词：铁路桥钝体箱梁涡激振动风洞试验模型比例尺雷诺数

Two APETALA2/ETHYLENE RESPONSE FACTORS coordinately with Ca MYC2 positively regulate capsaicinoid biosynthesis in pepper(Capsicum annuum)

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Horticultural Plant Journal 2025年第1期11卷 275-289页

作者： Jiali Song Renjian Liu Guoju Chen Jianjun Lei Zuoyang ning Xiangru Tang Xiaowan Xu Muxi Chen Bihao Cao Changming Chen Zhangsheng Zhu Key Laboratory of Biology and Genetic Improvement of Horticultural Crops(South China) Ministry of Agriculture and Rural AffairsCollege of HorticultureSouth China Agricultural UniversityGuangzhouGuangdong 510642China Guangdong Vegetable Engineering and Technology Research Center South China Agricultural UniversityGuangzhouGuangdong 510642China Henry Fok College of Biology and Agriculture Shaoguan UniversityShaoguanGuangdong 512005China College of Agriculture South China Agricultural UniversityGuangzhouGuangdong510642China Guangdong Key Laboratory for New Technology Research of Vegetables Vegetable Research InstituteGuangdong Academy of Agricultural SciencesGuangzhouGuangdong 510640China Guangdong Helinong Seeds CO.LTD.ShantouGuangdong 515800China

The transcriptional cascade and regulatory loop play crucial roles in regulating plant-specialized metabolite *** are unique to the genus Capsicum and confer a pungent flavor to its ***,the transcriptional regulation of capsaicinoid biosynthesis remains largely *** this study,two AP2/ERF transcription factors(TFs),CaERF102 and CaERF111,were characterized for their role in the capsaicinoid biosynthesis *** analysis of two ERFs and capsaicinoid biosynthetic genes(CBGs)suggested that they were associated with capsaicinoid *** ERFs encode nuclear-localized proteins and function as transcriptional activators through their C-terminal activation *** two ERF TFs participated in capsaicinoid biosynthesis by directly activating the promoters of key CBGs,and this activation was significantly enhanced when CaMYC2 was ***,CaERF102 and CaERF111 were found to interact with *** study helps elucidate the AP2/ERF TF regulatory network that governs capsaicinoid biosynthesis in Capsicum species.

关键词： Capsicum Specialized metabolites Pungency Transcription factor AP2/ERF MYC