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TRANSITIONAL FLOW IN CHANNEL JUNCTIONS

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Journal of Hydrodynamics 2004年第4期16卷 464-467页

作者： nihan-gen liuya-kun StateKeyLaboratoryofCoastalandOffshoreEngineering DalianUniversityofTechnologyDalian116024China

On the basis of energy and continuity equations a simple one-dimensionalformulation was proposed to predict the transitional flow at an open-channel junction. An empilicalrelation between the junction losses, the junction angle, and the discharge ratio was suggestedwhich agrees well with the experimental results. The results calculated by the present formulationfor the depth ratio were compared with the results of earlier one-dimensional formulations andexperiments. It is found that the present results coincide better with experiments than those ofothers.

关键词： open channel junctions energy losses transitional flow

Exploring the novel role of oligodendrocyte precursor cells in phagocytosis:beyond myelinogenesis

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Neural Regeneration Research 2025年第2期20卷 473-474页

作者： gen Hamanaka Ken Arai Neuroprotection Research Laboratories Departments of Radiology and NeurologyMassachusetts General Hospital and Harvard Medical SchoolCharlestownMAUSA

Roles of oligodendrocyte precursor cells in the central nervous system:Oligodendrocyte precursor cells(OPCs)have long been recognized for their critical role as precursors to oligodendrocytes,the primary myelin-producing *** precursors,OPCs mature and differentiate into oligodendrocytes,which contribute significantly to the formation of myelin sheaths around *** myelination,which is critical for the conduction of salutatory nerve impulses in the cerebral white matter,underscores the classical role of oligodendrocytes in central nervous system(CNS)***,because oligodendrocytes are differentiated cells that cannot proliferate.

关键词： critical system conduction

EFFECT OF AERATOR ON HYDRAULIC DRAG ACTING ON A CHUTE

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Journal of Hydrodynamics 2005年第1期17卷 34-42页

作者： nihan-gen LIXin ZHOUJing JINQiao StateKeyLaboratoryofCoastalandOffshoreEngineering DalianUniversityofTechnologyDalian116024China

The formulae used to calculate the friction in the non uniform flow chute were examined with the experimental data, and the results show that the accuracy of the formula is enough for engineering applications. A comparison between the results of friction respectively from the uniform flow assumption and the non uniform flow approximation indicates that the former is an order of magnitude larger than the latter in the case of steep chute. The hydraulic drag on a steep chute with aerators was measured on the hydraulic model directly and the coefficient of the aerator effect on the drag was obtained. The variation patterns of the wall shear just downstream of the aerators were investigated and the mechanism of the increase in the drag by aerator were analyzed qualitatively with the measured water depths just downstream the aerators.

关键词： overflow chute aerator wall shear hydraulic drag

Insight Into the Separation-of-Variable Methods for the Closed-Form Solutions of Free Vibration of Rectangular Thin Plates

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 329-355页

作者： Yufeng Xing Ye Yuan gen Li Institute of Solid Mechanics Beihang University(BUAA)Beijing100191China

The separation-of-variable(SOV)methods,such as the improved SOV method,the variational SOV method,and the extended SOV method,have been proposed by the present authors and coworkers to obtain the closed-form analytical solutions for free vibration and eigenbuckling of rectangular plates and circular cylindrical *** taking the free vibration of rectangular thin plates as an example,this work presents the theoretical framework of the SOV methods in an instructive way,and the bisection–based solution procedures for a group of nonlinear eigenvalue ***,the explicit equations of nodal lines of the SOV methods are presented,and the relations of nodal line patterns and frequency orders are *** is concluded that the highly accurate SOV methods have the same accuracy for all frequencies,the mode shapes about repeated frequencies can also be precisely captured,and the SOV methods do not have the problem of missing roots as well.

关键词： Separation-of-variable method Rayleigh quotient nodal line eigenvalue equation bisection method

ABRUPT DEFLECTED SUPERCRITICAL WATER FLOW-REVISED THEORY OF SHOCK WAVE

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Journal of Hydrodynamics 2006年第1期18卷 32-39页

作者： NI Han-gen LIU Ya-kun State Key Laboratory of Coastal and Offshore Engineering Dalian University of Technology Dalian 116024 China

The shock wave angle and depth ratio of the abrupt deflected supercritical water flow due to deflector was investigated experimentally and theoretically. A correction coefficient of the hydro-dynamic pressure ξ was introduced to generalize the momentum equation in the perpendicular direction to the shock front. An extensive series of tests were conducted in a 1 m wide flume with the Froude number ranging from 1.70 to 8.37, the deflection angle ranging from 5° to 40° and the length of deflector ranging from 0.28 m to 1 m. A dimensionless parameter K was defined to depict the ratio of the flow height to flow thickness. Test results show that the val ue of ~, the correction coefficient of the non-hydrostatic pres- sure distribution, decreases with the increase of the value of K An empirical relationship between the value of ξ and the val ue of K was proposed. It is indicated that the relative errors of the results calculated by the revised theory is much smaller than that obtained from the Ippen theory. Finally, a simple explicit expression was suggested to calculate the shock wave height ratio in consideration of the effect of the non-hydrostatic pressure distribution.

关键词： theory of shock wave abrupt deflection of supercritical flow trajectory type energy dissipater

MODIFIED LOG-WAKE LAWS FOR TURBULENT FLOW OF THE OUTER AND INNER REGIONS IN SMOOTH PIPES

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Journal of Hydrodynamics 2007年第2期19卷 188-194页

作者： LIU Ya-kun NI Han-gen State key Laboratory of Coastal and offshore Engineering Dalian University of Technology Dalian 116024 china

Based on theoretical analysis two modified log-wake laws for turbulent flow in smooth pipes are obtained, one is applicable to the outer region and other one to inner region, the new law for the outer region fits the velocity profile measured in smooth pipes by Zagarola very well and the effect of Reynolds number can be taken into consideration, the velocity profile for inner region satisfies the wall boundary conditions ,equals zero at the pipe wall and smoothly joins up with the velocity profile in outer region, the adopted eddy viscosity model is consistent with Laufer＇s, Nunner＇s and Reichardt＇s experimental data.

关键词： turbulent pipe flow eddy viscosity log-wakelaw outer and inner regions

Engineered Cancer Nanovaccines:A New Frontier in Cancer Therapy

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Nano-Micro Letters 2025年第2期17卷 134-168页

作者： Yijie Wang Congrui Liu Chao Fang Qiuxia Peng Wen Qin Xuebing Yan kun Zhang Central Laboratory and Department of Medical Ultrasound Sichuan Academy of Medical SciencesSichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaNo.32West Second SectionFirst Ring RoadChengdu 610072People’s Republic of China Department of Stomatology and Central Laboratory School of MedicineShanghai Tenth People’s HospitalTongji UniversityNO.301 Yan‑Chang‑Zhong RoadShanghai 200072People’s Republic of China Jiangsu Provincial Innovation and Practice Base for Postdoctors Suining People’s HospitalAffiliated Hospital of Xuzhou Medical UniversityNo.2Bayi West RoadSuiningXu Zhou 221000Jiangsu ProvincePeople’s Republic of China

Vaccinations are essential for preventing and treating disease,especially cancer nanovaccines,which have gained considerable interest recently for their strong anti-tumor immune *** can prompt the immune system to generate antibodies and activate various immune cells,leading to a response against tumor tissues and reducing the negative effects and recurrence risks of traditional chemotherapy and *** enhance the flexibility and targeting of vaccines,nanovaccines utilize nanotechnology to encapsulate or carry antigens at the nanoscale level,enabling more controlled and precise drug delivery to enhance immune *** nanovaccines function by encapsulating tumor-specific antigens or tumor-associated antigens within *** small size of these nanomaterials allows for precise targeting of T cells,dendritic cells,or cancer cells,thereby eliciting a more potent anti-tumor *** this paper,we focus on the classification of carriers for cancer nanovaccines,the roles of different target cells,and clinically tested cancer nanovaccines,discussing strategies for effectively inducing cytotoxic T lymphocytes responses and optimizing antigen presentation,while also looking ahead to the translational challenges of moving from animal experiments to clinical trials.

关键词： Cancer nanovaccines Immunotherapy Nanobiotechnology Immune targets Signaling pathway

Targets capture by distributed active swarms via bio-inspired reinforcement learning

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 210-221页

作者： kun Xu Yue Li Jun Sun Shuyuan Du Xinpeng Di Yuguang Yang Bo Li Institute of Biomechanics and Medical Engineering Applied Mechanics Laboratory Department of Engineering MechanicsTsinghua University Institute of Nuclear and New Energy Technology Tsinghua University Shanghai Aerospace Control Technology Institute Shanghai Key Laboratory of Aerospace Intelligent Control Technology College of Automation Engineering Nanjing University of Aeronautics and Astronautics

Natural swarms arranged from cells to herds are usually decentralized but display intriguing collective intelligence in coordinating individuals across large scales to efficiently achieve their common goals. Learning from nature may provide new strategies for controlling collective dynamics of synthetic swarms to accomplish specific functions. Here, we present a bioinspired computational framework that steers distributed active swarms to collectively capture and merge targets via reinforcement learning. We exploit collective milling structures of natural herds to cage the targets, and adopt a switching control policy inspired by sperms' chiral dynamics to optimize the trajectories of individuals, through which the active swarms can selforganize to enclose single or multiple distant targets in a dynamical, adaptive and scalable manner. There exists a critical swarm size, beyond which the excessive competition between agents would generate large mechanical forces, leading to capture instability but enabling the transition from short-distance to long-distance merging capture of multiple targets. This work provides physical insights into distributed active swarms and could offer a multilevel, decentralized strategy toward controlling swarm robotics in wide applications such as bio-medical devices, machine immunity, and target clearance.

关键词： swarm intelligence robotics multi-tasks artificial intelligence bionics

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论“慎捕”的法规范控制体系及实践问题破解

武汉大学学报（哲学社会科学版） 2025年第1期78卷 172-184页

作者：董坤中国社会科学院法学研究所中国社会科学院大学北京100720

历次修法中涉及逮捕的制度机制的演进轨迹和条文变化的内在逻辑表明,为实现“慎捕”目标,《中华人民共和国刑事诉讼法》(以下简称《刑事诉讼法》)已初步构筑起一套结构严谨、衔接有序、层次分明的关于逮捕权的法规范控制体系。该体系在... 详细信息

历次修法中涉及逮捕的制度机制的演进轨迹和条文变化的内在逻辑表明,为实现“慎捕”目标,《中华人民共和国刑事诉讼法》(以下简称《刑事诉讼法》)已初步构筑起一套结构严谨、衔接有序、层次分明的关于逮捕权的法规范控制体系。该体系在事前的权力配置阶段“两次分离”逮捕权,以具体社会危险性评估为重心改造逮捕要件;在事中的权力行使阶段以“兼听则明”为原则设计了充分听取控辩双方意见的审查逮捕机制;在事后的权力制约阶段要求检察院、法院及时纠正撤销错捕决定,释放犯罪嫌疑人。从司法办案的角度来看,现有的法规范控制体系在规则制定和程序执行时仍有不足和缺漏,如逮捕权分离不彻底,控辩意见“兼听”机制保障不充分,径行逮捕条件设计机械、不周延,当事人对错捕的救济途径缺失等。本轮《刑事诉讼法》修改应坚持“实践—规范”的互动逻辑,关注司法实践,将解决和弥补逮捕中的权力运行失范和权利保障不足等现实问题作为修法方向,破难题、开新局,不断推动中国刑事诉讼法治现代化进程。

关键词：慎捕法规范控制体系径行逮捕权利保障《刑事诉讼法》修改