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Gravity-Driven Instability in a Liquid Film Overlying an Inhomogeneous Porous Layer

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Chinese Physics Letters 2011年第2期28卷 144-147页

作者： ZHAO Si-Cheng LIU Qiu-Sheng nguyen-thi henri BILLIA Bernard Key Laboratory of Microgravity Institute of MechanicsChinese Academy of SciencesBeijing 100190 IM2NP UMR CNRS 6137Universitéd’Aix-Marseille III13397 Marseille Cedex 20France

A new model consisting of a liquid film overlying a saturated and inhomogeneous porous layer is *** concentrate on effects of inhomogeneity on transition of instability *** of the averaged porosity and the gradient of porosity distribution on the instability behaviors of a liquid-porous layer system are *** average permeability of the porous layer is a key factor to determine the penetration of convection in the system.

关键词： porosity porous layer

In-Situ Analyzing the Influence of Thermoelectromagnetic Convection on the Nucleation Ahead of the Advancing Interface During Directional Solidification

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Journal of Iron and Steel Research International 2012年第S1期19卷 381-385页

作者： WANG Jiang FAUTRELLE Yves REN Zhong-ming LI Xi nguyen-thi henri MANGELINCK-NOEL Nathalie SALLOUM ABOU JAOUDE Georges ZHONG Yun-bo KALDRE Imants BOJAREVICS Andris BULIGINS Leonid SIMAP/EPM-Madylam BP 75 ENSEEG38402 St-Martin d'HeresFrance Department of Material Science and Engineering Shanghai University Aix Marseille University Campus Saint-JeromeCase 14213397 Marseille Cedex 20France CNRS IM2NPCampus Saint-JeromeCase 14213397 Marseille Cedex 20 France University of Latvia/IPUL SalaspilsLatvia

Sn-3wt%Pb alloy was directionally solidified without and with a 0.08T transverse magnetic field(TMF),and real-time recorded by in-situ synchrotron X-ray *** indicate that TMF shortened the distance from the location of nucleation to the advancing interface,and accelerated the growth rate of the equiaxed crystal,which caused the columnar-to-equiaxed transition(CET)*** thermoelectromagnetic convection(TEMC)in front of the interface and around the crystal’s dendritic branch should respond to changes of the distance and the growth rate.

关键词： thermoelectromagnetic convection columnar-to-equiaxed transition synchrotron x-ray directional solidification

Solutal Convection of Liquid Al-3.5 wt%Li during Its Upward Solidification

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Chinese Physics Letters 2016年第6期33卷 53-56页

作者：赵思诚刘秋生 henri nguyen-thi Bernard Billia Department of Mechanics School of Civil EngineeringBeijing Jiaotong University Jiangsu Key Laboratory of Engineering Mechanics Southeast University Key Laboratory of Microgravity Institute of MechanicsChinese Academy of Sciences IM2NP UMR CNRS 6137Universite d'Aix-Marseille

The onset of solutal convection during the directional solidification of Bridgman type of liquid Al-3.5 wt%Li is studied. Based on the analysis of a liquid-inhomogeneous-porous-double-layer system, a bimodal feature of neutral stability curve is found. The pulling rate is ascertained as the governing parameter for the mode transition, i.e., it determines whether the microstructure in the mushy layer is related to convection after the system destabilizes.

关键词： in it of is mode for Li Al

Revisiting dynamics and models of microsegregation during polycrystalline solidification of binary alloy

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Journal of Materials Science & Technology 2021年第15期74卷 155-167页

作者： Tongzhao Gong Yun Chen Shanshan Li Yanfei Cao Dianzhong Li Xing-Qiu Chen Guillaume Reinhart henri nguyen-thi Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei230026China Aix Marseille Univ Universite de ToulonCNRSIM2NPMarseilleFrance

Microsegregation formed during solidification is of great importance to material *** conventional Lever rule and Scheil equation are widely used to predict solute ***,these models always fail to predict the exact solute concentration at a high solid fraction because of theoretical ***,the dynamics of microsegregation during polycrystalline solidification of refined Al-Cu alloy is studied via two-and three-dimensional quantitative phase-field *** with different grain refinement level,cooling rate,and solid diffusion coefficient demonstrate that solute segregation at the end of solidification(*** the solid fraction is close to unit)is not strongly correlated to the grain morphology and back *** independences are in accordance with the Scheil equation which only relates to the solid fraction,but the model predicts a much higher liquid concentration than ***,based on the quantitative phase-field simulations,a new analytical microsegregation model is *** the Scheil equation or the Lever rule that respectively overestimates or underestimates the liquid concentration,the present model predicts the liquid concentration in a pretty good agreement with phase-field simulations,particularly at the late solidification stage.

关键词： Microsegregation Grain refinement Cooling rate Back diffusion Phase-field method

Short mucin 6 alleles are associated with H pylori infection

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World Journal of Gastroenterology 2006年第37期12卷 6021-6025页

作者： Thai V nguyen Marcel JR Janssen Paulien Gritters René HM te Morsche Joost PH Drenth henri van Asten Robert JF Laheij Jan BMJ Jansen Department of Gastroenterology Can Tho University of Medicine and Pharmacy Can Tho Viet Nam Department of Gastroenterology and Hepatology Radboud University Nijmegen Medical Centre Nijmegen The Netherlands Nijmegen Institute for International Health Radboud University Nijmegen Medical Centre Nijmegen The Netherlands

AIM： To investigate the relationship between mucin 6 （MUC6） VNTR length and Hpylori infection. METHODS： Blood samples were collected from patients visiting the Can Tho General Hospital for upper gastrointestinal endoscopy. DNA was isolated from whole blood, the repeated section was cut out using a restriction enzyme （Pvu 11） and the length of the allele fragments was determined by Southern blotting. Hpylori infection was diagnosed by ^14C urea breath test. For analysis, MUC6 allele fragment length was dichotomized as being either long （〉 13.5 kbp） or short （≤ 13.5 kbp） and patients were classified according to genotype [long- long （LL）, long-short （LS）, short-short （SS）]. RESULTS： 160 patients were studied （mean age 43 years, 36% were males, 58% H pylori positive）. MUC6 PvuⅡ-restricted allele fragment lengths ranged from 7 to 19 kbp. Of the patients with the LL, LS, SS MUC6 genotype, 43% （24/56）, 57% （25/58） and 76% （11/46） were infected with Hpylori, respectively （P = 0.003）. CONCLUSION： Short MUC6 alleles are associated with H pylori infection.

关键词： H pylori Mucin 6 Polymorphism Variable number of tandem repeats

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上海浦东嘉里亲子会员中心中国上海

世界建筑导报 2019年第4期34卷 91-93页

作者： William nguyen Van Thanh Ha Luca Maccarinelli 无不详 SPARK思邦

SPARK思邦完成了浦东嘉里城Living Room的设计,这是一个供嘉里会员使用的亲子社交空间。这个120平米的空间位于浦东嘉里购物中心的B1层,灵感来自"魔法森林"的民间传说,旨在激发孩子和父母的好奇心、乐趣和互动。嘉里的"Living Room"概... 详细信息

SPARK思邦完成了浦东嘉里城Living Room的设计,这是一个供嘉里会员使用的亲子社交空间。这个120平米的空间位于浦东嘉里购物中心的B1层,灵感来自"魔法森林"的民间传说,旨在激发孩子和父母的好奇心、乐趣和互动。嘉里的"Living Room"概念是业主策略的一部分,旨在面对颠覆性的线上/线下购物竞争,为其会员顾客创造丰富的购物体验。

关键词：上海浦东会员亲子中国 Room 购物中心 SPARK 民间传说

Subclinical proximal tubulopathy in hepatitis B:The roles of nucleot(s)ide analogue treatment and the hepatitis B virus

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World Journal of Hepatology 2020年第12期12卷 1326-1340页

作者： Anais Brayette Marie Essig Paul Carrier Marilyne Debette-Gratien Anais Labrunie Sophie Alain Marianne Maynard Nathalie Ganne-Carrie Eric nguyen-Khac Pauline Pinet Victor De Ledinghen Christophe Renou Philippe Mathurin Claire Vanlemmens Vincent Di Martino Anne Gervais Juliette Foucher Fouchard-Hubert Isabelle Julien Vergniol Isabelle Hourmand-Ollivier Daniel Cohen Xavier Duval thierry Poynard Marc Bardou Armand Abergel Manh-Thong Dao thierry Thevenot Jean-Baptiste Hiriart Valerie Canva Guillaume Lassailly Christine Aurières Nathalie Boyer Dominique Thabut Pierre-henri Bernard Matthieu Schnee Dominique Larrey Bertrand Hanslik Severine Hommel Jeremie Jacques Veronique Loustaud-Ratti U1248 INSERM Department of Hepatology and GastroenterologyUniv.LimogesCHU LimogesLimoges F-87000France U1248 INSERM Department of Nephrology and TransplantationCHU LimogesLimoges F-87000France Department of Center of Epidemiology Biostatistics and Research MethodologyCHU LimogesLimoges F-87000France U1092 INSERM Department of VirologyCHU LimogesLimoges F-87000France Department of Hepatology Croix-Rousse University Hospital of LyonLyon 69004France Department of Hepatology Jean Verdier University Hospital of BondyBondy 93140France Department of Hepato-Gastroenterology Amiens University HospitalAmiens 80054France Department of Infectious Diseases CHU LimogesLimoges F-87000France Department of Hepatology Haut Leveque HospitalBordeaux University HospitalPessac 33604France Department of Gastroenterology Hyeres HospitalHyeres 83407France Department of Hepato-Gastroenterology Claude Huriez University HospitalLille 59037France Department of Hepatology Jean Minjoz University HospitalBesançon 25030France Department of Infectious Diseases Bichat University HospitalParis 75018France Department of Hepatology University Hospital of AngersAngers 49933France Department of Hepato-Gastroenterology and Nutrition University Hospital of CaenCaen 14033France Department of General Medecine University Hospital of CaenCaen 14000France Department of Hepatology La Pitié-Salpêtrière University HospitalParis 75651France Department of Hepatology and Gastroenterology Dijon University HospitalDijon 21079France Department of Hepatology and Gastroenterology Estaing University HospitalClermont Ferrand 63003France Department of Hepatology Beaujon University HospitalClichy 92110France Department of Hepatology Saint-AndréUniversity HospitalBordeaux 33000France Department of Hepatology and Gastroenterology La Roche-Sur-Yon Hospital CenterLa Roche-Sur-Yon 85000France Department of Hepatology and Gastroenterology University Hospital of MontpellierMontpellier 34295France Department of Addictology Hospita

BACKGROUND The recommended monitoring tools for evaluating nucleot(s)ide analogue renal toxicity,such as estimated glomerular filtration rate(eGFR)and phosphatemia,are late markers of proximal *** early markers are available,but no consensus exists on their *** To determine the 24 mo prevalence of subclinical proximal tubulopathy(SPT),as defined with early biomarkers,in treated vs untreated hepatitis B virus(HBV)-monoinfected *** A prospective,non-randomized,multicenter study of HBV-monoinfected patients with a low number of renal comorbidities was *** patients were separated into three groups:Naïve,starting entecavir(ETV)treatment,or starting tenofovir disoproxil(TDF)*** on the early markers of SPT,the eGFR and phosphatemia,were collected *** was defined as a maximal tubular reabsorption of phosphate/eGFR below 0.8 mmoL/L and/or uric acid fractional excretion above 10%.The prevalence and cumulative incidence of SPT at month 24(M24)were *** data were analyzed using analyses of variance or Kruskal-Wallis tests,whereas chi-squared or Fisher’s exact tests were used to analyze qualitative *** analyses were used to adjust for any potential confounding *** Of the 196 patients analyzed,138(84 naïve,28 starting ETV,and 26 starting TDF)had no SPT at *** M24,the prevalence of SPT was not statistically different between naïve and either treated group(21.1%vs 30.7%,P<0.42 and 50.0%vs 30.7%,P=0.32 for ETV and TDF,respectively);no patient had an eGFR lower than 50 mL/min/1.73 m²or phosphatemia less than 0.48 mmoL/*** the multivariate analysis,no explanatory variables were identified after *** cumulative incidence of SPT over 24 mo(25.5%,13.3%,and 52.9%in the naïve,ETV,and TDF groups,respectively)tended to be higher in the TDF group vs the naïve group(hazard ratio:2.283,P=0.05).SPT-free survival at M24 was 57.6%,68.8%,and 23.5%for the naïve,ETV,and TD

关键词： Hepatitis B virus Proximal tubulopathy Biomarkers Renal insufficiency Nucleoside analogues

每日吸食大麻是慢性丙型肝炎患者肝纤维化进展的危险因素

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世界核心医学期刊文摘（胃肠病学分册） 2005年第10期1卷 39-39页

作者： Hézode C. Roudot-Thoraval F. nguyen S. A. Mallat 李翔 Service d'Hépatologie et de Gastroentér-ologie Centre Hospitalier Universitaire Henri Mondor 51 ave. Marechal Lattre Tassigny 94010 Créteil Cedex France

Cannabinoids present in Cannabis sativa (marijuana) exert biological effects via cannabinoid receptors CB1 and CB2. We recently demonstrated that CB1 and CB2 receptors regulate progression of experimental liver fibrosis. We therefore investigated the impact of cannabis smoking on fibrosis progression rate in patients with chronic hepatitis C (CHC). Two hundred seventy consecutive untreated patients with CHC of known duration undergoing liver biopsy were studied. Demographic, epidemiological,metabolic, and virological data were recorded, and detailed histories of cannabis, alcohol, and tobacco use over the span of hepatitis C virus infection were obtained. Fibrosis stage, steatosis, and activity grades were scored according to Metavir system. Patientswere categorized as noncannabis users (52.2%), occasional users (14.8%), or daily users (33.0%), and the relationship between cannabis use and fibrosis progression rate (FPR) or fibrosis stage was assessed. On multivariate analysis, six factors were independently related to a FPR greater than 0.074 (median value of the cohort): daily cannabis use (OR = 3.4 [1.5-7.4]), Metavir activity grade A2 or higher (OR = 5.4 [2.9-10.3]), age at contamination of more than 40 years (OR = 10.5 [3.0-37.1]), genotype 3 (OR = 3.4 [1.5-7.7]), excessive alcohol intake (OR = 2.2 [1.1-4.5]), and steatosis (OR = 2.0 [1.0-4.1]). Daily cannabis use was also an independent predictor of a rapid FPR ( >0.15) (OR = 3.6 [1.5-7.5]). Finally, severe fibrosis (≥F3) was also predicted by daily cannabis use (OR = 2.5 [1.1-5.6]; P = .034), independently of Metavir activity grade, excessive alcohol intake, age at liver biopsy, steatosis, and tobacco smoking. In conclusion, daily cannabis smoking is significantly associated with fibrosis progression during CHC. Patients with ongoing CHC should be advised to refrain from regular cannabis use.

关键词：慢性丙型肝炎肝纤维化肝组织活检脂肪变性详细病史活动程度研究人群进展率人口统计学吸食者