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Heavy metal stress strengthens the stability and complexity of microbial molecular ecological networks in Sanyang wetland sediments

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Journal of Oceanology and limnology 2025年第1期43卷 103-118页

作者： Shengwei WU Huixi ZOU nan li Xiufeng YAN Wen liU College of life and Environmental Science Wenzhou UniversityWenzhou 325035China Institute for Eco-environmental Research of Sanyang Wetland Wenzhou UniversityWenzhou 325035China Key Laboratory of Soil Contamination Bioremediation of Zhejiang Province School of Environmental&Resource SciencesZhejiang Agriculture and Forestry UniversityHangzhou 311300China

Pollution from heavy metals(HMs)(Cd,As,Cr,and Ni,etc.)has become a serious environmental issue in urban wetland ecosystems with more and more *** studies conducted in agricultural soils,rivers,and lakes demonstrated that microbial communities exhibit a response to HM ***,little is known about the response of microbial communities to HM pollution in urban wetland *** examined how heavy metals affect the stability of the microbial networks in the sediments of Sanyang wetland,Wenzhou,*** environmental parameters,including HMs,TC(total carbon),TN(total nitrogen),TP(total phosphorus),S,and pH,varied profoundly between moderately and heavily polluted areas in shaping microbial ***,the microbial community composition in moderately polluted sites correlated significantly(Plinks,average degree,average clustering coefficient,connectance,relative modularity,robustness,and ***,the structural equation modeling analysis demonstrated a positive correlation between the stability of microbial networks and Cd,TN,TP,and S in heavily polluted ***,in moderately polluted sites,the correlation was positively linked to Cd,Ni,and sediment *** implies that Cd could potentially play a crucial role in affecting the stability of microbial *** study shall enhance our comprehension of microbial co-occurrence patterns in urban wetland ecosystems and offer insights into the ways in which microbial communities respond to environmental factors in varying levels of HM pollution.

关键词： heavy metal(HM) urban wetland microbial networks network stability

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Epigenetic basis for the establishment of ruminal tissue-specific functions in bovine fetuses and adults

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Journal of Genetics and Genomics 2025年第1期52卷 78-92页

作者： Jing Wang Wen Yuan Fang liu Guangbo liu Xiaoxiong Geng Chen li Chenchen Zhang nan li Xueling li State Key Laboratory of Reproductive Regulation&Breeding of Grassland livestock Research Center for Laboratory Animal ScienceInner Mongolia UniversityHohhotInner Mongolia 010070China College of Chemistry and Chemical Engineering Engineering Research Center of Dairy Quality and Safety Control TechnologyMinistry of EducationInner Mongolia UniversityHohhotInner Mongolia 010070China

Epigenetic regulation in the rumen,a unique ruminant organ,remains largely unexplored compared with other tissues studied in model *** this study,we perform an in-depth analysis of the epigenetic and transcriptional landscapes across fetal and adult bovine tissues as well as pluripotent stem *** the extensive methylation differences across various stages and tissues,we identify tissue-specific differentially methylated regions(tsDMRs)unique to the rumen,which are crucial for regulating epithelial development and energy *** tsDMRs cluster within super-enhancer regions that overlap with transcription factor(TF)binding *** models indicate that DNA methylation,along with H3K27me3 and H3K27ac,can be used to predict enhancer *** upstream TFs,including SOX2,FOSL1/2,and SMAD2/3,primarily maintain an inhibitory state through bivalent modifications during fetal *** functional genes are maintained mainly in a stable repressive state via DNA methylation until differentiation is *** study underscores the critical role of tsDMRs in regulating distal components of rumen morphology and function,providing key insights into the epigenetic regulatory mechanisms that may influence bovine production traits.

关键词： Rumen Epigenetics DNA methylation tsDMRs Enhancers

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More Than Words The legendary career of Tang Wensheng,China’s interpreter extraordinaire

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Beijing Review 2025年第2期68卷 42-43页

作者： li nan 不详

Tang Wensheng,81,typed a question into the dialog box of Chinese search engine Baidu's artificial intelligence(AI)chatbot service,Ernie Bot:How do I install drivers for a printer and a scanner on a desktop computer?Within seconds,the answer popped *** followed the step-by-step instructions and successfully installed the two drivers on her own.

关键词： scanner install printer

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SEAFOOD WITHOUT THE SEAGreenhouse aquaculture is a fledgling industry in Xizang Autonomous Region

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北京周报（英文版） 2025年第1期68卷 16-17页

作者： li nan 不详

Fresh fish was the best-selling product in Xitun Supermarket in Nyingchi City,Xizang Autonomous Region,in the second half of 2024."They were really fresh and usually sold out within half an hour,"He Mei,manager of the... 详细信息

关键词： seafood without

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Effect of rolling schedules on ridging resistance of ultra-thin ferritic stainless steel foil

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Journal of Iron and Steel Research International 2025年第1期32卷 198-214页

作者： Jing-wei Zhao Qing-zhong Xie li-nan Ma Cun-long Zhou Zheng-yi Jiang Xi liao Xiao-guang Ma College of Mechanical and Vehicle Engineering Taiyuan University of TechnologyTaiyuan030024ShanxiChina Engineering Research Center of Advanced Metal Composites Forming Technology and Equipment Ministry of EducationTaiyuan030024ShanxiChina National Key Laboratory of Metal Forming Technology and Heavy Equipment Ministry of Science and TechnologyTaiyuan030024ShanxiChina School of Mechanical Engineering Taiyuan University of Science and TechnologyTaiyuan 030024ShanxiChina School of Mechanical MaterialsBiomedical and Mechatronic EngineeringUniversity of WollongongWollongongNSW2522Australia Shanxi Taigang Stainless Steel Precision Strip Co. Ltd.Taiyuan 030006ShanxiChina

The effect of rolling schedules on the ridging resistance of ultra-thin ferritic stainless steel(FSS)430 foil was evaluated by studying the microstructure and *** results show that specimens processed with three-pass cold rolling under the reductions of 40%,40%and 31%,respectively,exhibit improved ridging resistance owing to the microstructural refinement and the texture structure optimization.A nearly 40%reduction of ridging height can be achieved using the proposed rolling schedule compared to the other two rolling *** addition,the effect of annealing temperature after cold rolling on the ridging resistance of FSS 430 foil is also found to be crucial,and an optimal annealing temperature of 900℃ is obtained for FSS 430 foil with high ridging ***,the improvement in the ridging resistance of FSS 430 foil can be attributed to the reduction in the fraction of{001}and{114}components by optimization of the rolling and annealing processes.

关键词： Ferritic stainless steel foil Ridging Cold rolling Annealing Microstructure Texture

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The assembly and activation of the PANoptosome promote porcine granulosa cell programmed cell death during follicular atresia

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Journal of Animal Science and Biotechnology 2025年第1期16卷 121-135页

作者： Hao Wu Yingxue Han Jikang liu Rong Zhao Shizhen Dai Yajun Guo nan li Feng Yang Shenming Zeng National Engineering Laboratory for Animal Breeding Key Laboratory of Animal Genetics and Breeding of the Ministry of AgricultureCollege of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China Department of Clinical Sciences College of Veterinary MedicineChina Agricultural UniversityBeijing 100193China College of Animal Science and Technology Henan Agricultural UniversityZhengzhou 450046China

Background Follicular atresia significantly impairs female fertility and hastens reproductive *** of granulosa cells is the primary cause of follicular *** and necroptosis,as additional forms of pro-grammed cell death,have been reported in mammalian ***,the understanding of pyroptosis and necrop-tosis pathways in granulosa cells during follicular atresia remains *** study explored the effects of pro-grammed cell death in granulosa cells on follicular atresia and the underlying *** The results revealed that granulosa cells undergo programmed cell death including apoptosis,pyroptosis,and necroptosis during follicular *** the first time,we identified the formation of a PANoptosome com-plex in porcine granulosa *** complex was initially identified as being composed of ZBP1,RIPK3,and RIPK1,and is recruited through the RHIM ***,we demonstrated that caspase-6 is activated and cleaved,interacting with RIPK3 as a component of the *** stress may exacerbate the activation of the PANop-tosome,leading to programmed cell death in granulosa *** Our data identified the formation of a PANoptosome complex that promoted programmed cell death in granulosa cells during the process of follicular *** findings provide new insights into the molecular mechanisms underlying follicular atresia.

关键词： Follicular atresia Granulosa cells PANoptosome Programmed cell death

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Protein@AuNPs Synthesized by Microfluidic Droplet System and Application in Cu(II)and L-Cysteine Sensing

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Chemical Research in Chinese Universities 2025年第1期41卷 131-137页

作者： ZHU Xiaotong li Xinyu QI li ZHANG Rongyue li nan HE Xiaonan QIAO Juan College of New Materials and Chemical Engineering Beijing Institute of Petrochemical TechnologyBeijing102617P.R.China Beijing National Laboratory for Molecular Sciences Key Lab of Analytical Chemistry for Living BiosystemsInstitute of ChemistryChinese Academy of SciencesBeijing100190P.R.China

In this study,Pepsin@AuNPs(Pep@AuNPs)and Trypsin@AuNPs(Try@AuNPs)were synthesized by a microfluidic droplet system using Pepsin and Trypsin as protection reagents and NaOH as reducing *** to the synthesis method in a flask,the AuNPs synthesized by the microfluidic droplet system demonstrated uniform nucleation,superior ultraviolet absorption performance,high stability and short preparation cycles(15 min).The detection range of Cu(II)by Pep@AuNPs was 1.0–100.0µmol/L and the detection limit was 0.3µmol/*** detection range of L-Cysteine by Try@AuNPs was 0.3–250.0 mmol/L and the detection limit was 0.1 mmol/*** universal method provides an effective strategy for the detection of bioactive molecules,such as metal ions and amino acids by AuNPs with protein as a protective agent.

关键词： Microfluidic droplet system AuNPs Trypsin Pepsin

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Contribution of China's carbon budget on global radiative forcing

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Journal of Geographical Sciences 2025年第2期35卷 233-251页

作者： li nan CUI Yaoping liU Xiaoyan SHI Zhifang li Mengdi Michael E MEADOWS Key Laboratory of Geospatial Technology for the Middle and Lower Yellow River Regions (Henan University) Ministry of Education College of Environment and Planning Henan University Dabieshan National Observation and Research Field Station of Forest Ecosystem at Henan Department of Environmental and Geographic Sciences University of Cape Town

China is the world's largest carbon dioxide（CO2） emitter and a major trading country. Both anthropogenic and natural factors play a critical role in its carbon budget. However,previous studies mostly focus on evaluating anthropogenic emissions or the natural carbon cycle separately, and few included trade-related（import and export） CO2emissions and its contribution on global warming. Using the CarbonTracker CT2019 assimilation dataset and China trade emissions from the Global Carbon Project, we found that the change trend of global CO2flux had obvious spatial heterogeneity, which is mainly affected by anthropogenic CO2flux. From 2000 to 2018, carbon emissions from fossil fuels in the world and in China all showed an obvious increasing trend, but the magnitude of the increase tended to slow *** 2018, the radiative forcing（RF） caused by China's import and export trade was-0.0038 W m-2, and the RF caused by natural carbon budget was-0.0027 W m-2, offsetting 1.54% and 1.13% of the RF caused by fossil fuels that year, respectively. From 2000 to 2018, the contribution of China's carbon emission from fossil fuels to global RF was 11.32%. Considering China's import and export trade, the contribution of anthropogenic CO2emission to global RF decreased to 9.50%. Furthermore, taking into account the offset of carbon sink from China's terrestrial ecosystems, the net contribution of China to global RF decreased to 7.63%. This study demonstrates that China's terrestrial ecosystem and import and export trade are all mitigating China's impact on global anthropogenic warming, and also confirms that during the research process on climate change, comprehensively considering the carbon budget from anthropogenic and natural carbon budgets is necessary to systematically understand the impacts of regional or national carbon budgets on global warming.

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Research on the X-ray polarization deconstruction method based on hexagonal convolutional neural network

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Nuclear Science and Techniques 2025年第2期36卷 49-61页

作者： Ya-nan li Jia-Huan Zhu Huai-Zhong Gao Hong li Ji-Rong Cang Zhi Zeng Hua Feng Ming Zeng Key Laboratory of Particle&Radiation Imaging Tsinghua UniversityMinistry of EducationBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Department of Astronomy Tsinghua UniversityBeijing 100084China StarDetect Co. LtdBeijing 100084China

Track reconstruction algorithms are critical for polarization *** neural networks(CNNs)are a promising alternative to traditional moment-based track reconstruction ***,the hexagonal grid track images obtained using gas pixel detectors(GPDs)for better anisotropy do not match the classical rectangle-based CNN,and converting the track images from hexagonal to square results in a loss of *** developed a new hexagonal CNN algorithm for track reconstruction and polarization estimation in X-ray polarimeters,which was used to extract the emission angles and absorption points from photoelectron track images and predict the uncer-tainty of the predicted emission *** simulated data from the Polarlight test were used to train and test the hexagonal CNN *** individual energies,the hexagonal CNN algorithm produced 15%-30%improvements in the modulation factor compared to the moment analysis method for 100%polarized data,and its performance was comparable to that of the rectangle-based CNN algorithm that was recently developed by the Imaging X-ray Polarimetry Explorer team,but at a lower computational and storage cost for preprocessing.

关键词： X-ray polarization Track reconstruction Deep learning Hexagonal conventional neural network

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Correlations of three scoring systems with the prognosis of patients with liver cirrhosis complicated with sepsis syndrome

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World Journal of Gastrointestinal Surgery 2025年第3期17卷 150-160页

作者： li-nan liu Yu-Fei Chang Hui Wang Department of Emergency Beijing Ditan Hospital Capital Medical UniversityBeijing 100102China

BACKGROUND Severe symptoms associated with sepsis syndrome(SS)are considered a severe threat,which not only increases therapeutic difficulty but also causes a prognostic mortality ***,at present,few related studies focused on the application of different score scales for disease and prognosis assessment in liver cirrhosis(LC)complicated with *** To determine the correlations of the model for end-stage liver disease(MELD),sequential organ failure assessment(SOFA),and modified early warning score(MEWS)points with the prognosis of patients with LC complicated with *** This retrospective analysis included 426 LC cases from February 2019 to April *** them,225 cases that were complicated with SS were assigned to the LC+SS group,and 201 simple LC cases were included in the LC *** differences in MELD,SOFA,and MEWS scores were compared,as well as their diagnostic value for LC+*** correlations of the three scores with the progno-sis of patients with LC+SS were further analyzed,as well as the related risk factors affecting patients’outcomes,after the follow-up *** MELD,SOFA,and MEWS scores were all higher in the LC+SS group vs the LC group,and their combined assessment for LC+SS revealed a diagnostic sensi-tivity and a specificity of 89.66%and 90.84%,respectively(Plity rate of 25.78%.Deceased pa-tients presented higher MELD,SOFA,and MEWS points than those who survived(Plicated with SS,and they demonstrated great significance in assessing prognosis,which provides a reliable prognosis guarantee for patients with LC+***,their assessment effects remain limited,which is worthy of further investigation by more in-depth and rigorous experimental a

关键词： Model for end-stage liver disease Sequential organ failure assessment Modified early warning score Cirrhosis Sepsis syndrome

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