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Journal of Integrative Agriculture 2017年第7期16卷 1467-1473页

作者： TANG Liang GAO Hong Hirooka Yoshihiro Homma Koki nakazaki tetsuya LIU Tian-sheng Shiraiwa Tatsuhiko XU Zheng-jin Rice Research Institute Shenyang Agricultural University/Key Laboratory of Northeast Rice Biology and BreedingMinistry of Agriculture/Key Laboratory of Northern japonica Super Rice BreedingMinistry of EducationShenyang 110866P.R.China Liaoning Academy of Agricultural Sciences Shenyang 110161P.R.China Laboratory of Plant Breeding Graduate School of AgricultureKyoto UniversityKyoto 606-8502Japan

The erect panicle （Ep） type is an important characteristic for japonica super rice in Northeast China and plays a significant role in enhancing yield. The Ep type is considered to be a genetic ideotype resource to the japonica super rice group by virtue of its agronomic advantages such as grain number per panicle and biomass. This study addresses the effects of nitrogen and planting density conditions on yielding performance regarding panicle type （PT） using the recombinant inbred line （RIL） population derived from the cross between an Ep variety Liaogeng 5 and non-Ep variety Wanlun 422. The genetics underlying the Ep type proved to be robust not only for panicle-type optimization but also plant height, panicle length, flag leaf length and seed density. We also found that regardless of nitrogen and density, correlation between harvest index （HI） and plant height was not significant in Ep type whatever the nitrogen and density. The application of Ep type provides a potential strategy for yield improvement by increasing biomass through HI maintainable in rice.

关键词： super rice erect panicle harvest index nitrogen planting density

Effects of erect panicle genotype and environment interactions on rice yield and yield components

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Journal of Integrative Agriculture 2023年第3期22卷 716-726页

作者： WANG Yuan-zheng Olusegun IDOWU WANG Yun HOMMA Koki nakazaki tetsuya ZHENG Wen-jing XU Zheng-jin SHIRAIWA Tatsuhiko Rice Research Institute Liaoning Academy of Agricultural SciencesShenyang 110101P.R.China Division of Agronomy and Horticulture Science Graduate School of AgricultureKyoto UniversityKyoto 606-8501Japan Rice Research Institute Shenyang Agricultural University/Key Laboratory of Northeast Rice Biology and BreedingMinistry of Agriculture and Rural Affairs/Key Laboratory of Northern Japonica Super Rice BreedingMinistry of EducationShenyang 110866P.R.China Division of Biological Resource Sciences Graduate School of Agricultural ScienceTohoku UniversitySendai 980-8576Japan

The dense and erect panicle (EP) genotype conferred by DEP1 has been widely used in the breeding of high-yield Chinese japonica rice ***,the breeding value of the EP genotype has rarely been determined at the plant population ***,the effects of the interaction of EP genotype and the environment at different locations and times on rice yield and its various components were investigated in this *** sets of near-isogenic lines (NILs)of EP and non-EP (NEP) genotypes with Liaojing 5 (LG5) and Akitakomachi (AKI) backgrounds were grown in the field in 2016 and 2017 in Shenyang,China,and Kyoto,*** 2018,these sets were grown only in Kyoto,*** average yields of the EP and NEP genotypes were 6.67 and 6.13 t ha^(-1)for the AKI background,and 6.66 and 6.58 t ha^(-1)for the LG5 background,*** EP genotype positively affected panicle number (PN) and grain number per square meter (GNPM),mostly resulting in a positive effect on harvest index (HI).In contrast,the EP genotype exerted a negative effect on thousand-grain weight (KGW).The ratio of the performance of the EP genotype relative to the NEP genotype in terms of yield and total biomass correlated positively with mean daily solar radiation during a 40-day period around *** results indicate that the effectiveness of the EP genotype depends on the availability of solar radiation,and the effect of this genotype is consistently positive for sink formation,conditional in terms of source capacity,and positive in a high-radiation environment.

关键词： erect panicle genotype by environment interaction rice(Oryza sativa L.) solar radiation yield

直立穗型基因与环境对水稻产量及产量构成因素的相互作用

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直立穗型基因与环境对水稻产量及产量构成因素的相互作用

Efficacy of direct-acting antiviral treatment for chronic hepatitis C: A single hospital experience

2019年中国作物学会学术年会

作者：王远征 Olusegun Idowu 王韵 Homma Koki nakazaki tetsuya 徐正进 Shiraiwa Tatsuhiko 沈阳农业大学水稻研究所/教育部和辽宁省北方粳稻遗传育种重点实验室/农业部东北水稻生物学与遗传育种重点实验室 Division of Agronomy and Horticulture Science Graduate School of Agriculture Kyoto University Department of Agronomy Graduate School of Science Tohoku University

水稻直立穗型作为继矮化和理想株型后水稻株型适应高产要求的又一重要形态变化,直立穗型的主要生理生态特点为群体结构合理,光照分布均匀,冠层内光照强度、湿度、温度及CO等生态条件优越,同时降低了反射辐射,促进了气体交换,水稻生长中... 详细信息

水稻直立穗型作为继矮化和理想株型后水稻株型适应高产要求的又一重要形态变化,直立穗型的主要生理生态特点为群体结构合理,光照分布均匀,冠层内光照强度、湿度、温度及CO等生态条件优越,同时降低了反射辐射,促进了气体交换,水稻生长中后期群体生长率较高,从而具有较高的生物产量。由DEP1基因调控的直立穗型基因(EP基因)被广泛应用到中国粳稻的高产育种中,然而目前EP基因在群体水平上对育种应用价值的研究却很少,本研究的目的为确定EP基因型与不同生态地点、不同年份的环境对水稻产量及产量构成要素的相互作用,通过构建两套以秋田小町及辽粳5号为遗传背景,基因型为EP及NEP的近等基因系,并在2016和2017及2018年种植在沈阳(中国)及京都(日本)两地。秋田小町背景下EP及NEP的平均产量分别为6.67吨/公顷及6.13吨/公顷,辽粳5背景下EP及NEP的平均产量分别为6.66吨/公顷及6.58吨/公顷。EP基因的作用可以增加穗数及每平方米穗粒数从而增加收获指数,但EP基因降低了千粒重。EP基因型与NEP基因型在产量的比值及在生物产量上的比值与抽穗前15天到抽穗后25天间40天均日辐射呈显著正相关,说明EP基因型的有效性取决于太阳辐射的有效性。本实验研究表明,EP基因型始终对水稻物质形成有积极作用,但却需要在高的太阳辐射下对与水稻源产生积极影响,由于EP基因型在两种遗传背景间的对物候学响应的差异,使得仅在秋田小町背景下EP基因型的效用具有较高的产量潜力,EP基因型在两个遗传背景下对穗数及每平方米穗粒数的作用都呈现出一致的促进作用,进而EP基因型表现出对水稻经济系数的积极影响。

关键词：直立穗型基因基因型与环境互作影响水稻太阳辐射产量

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World Journal of Hepatology 2018年第1期10卷 88-94页

作者： Rena Kaneko Natsuko nakazaki Risa Omori Yuichiro Yano Masazumi Ogawa Yuzuru Sato Department of Gastroenterology Japan Organization of Occupational Health and Safety Kanto Rosai Hospital

AIM To evaluate the efficacy of direct-acting antivirals(DAAs) in Kanto Rosai Hospital. METHODS All patients with hepatitis C virus(HCV) who underwent DAA prescription were enrolled in this study. The present study was a single center retrospective analysis using patients infected with HCV genotype 1 or 2. Resistance analysis was performed by using direct sequencing and cycleave PCR in genotype 1 patients treated with interferon(IFN)-free DAA. The primary endpoint was sustained virologic response at 12 wk after therapy(SVR12).RESULTS A total of 117 patients participated in the study, including 135 with genotype 1 and 42 with genotype 2. Of the 135 patients with genotype 1, 16 received protease inhibitor + IFN + ribavirin and all achieved SVR. Of the 119 patients who received IFN-free DAA(in different combinations), 102 achieved SVR and 9 failed(7/9 were on daclatasvir/asunaprevir and 2/9 on ledipasvir/sofosbuvir). Efficacy analysis was done only for 43 patients who received daclatasvir/asunaprevir. From this analysis, Y93 resistance-associated substitutions were significantly correlated with *** The SVR rate was 98% for genotype 1 and 100% for genotype 2. However, caution is needed for HCV NS5 A resistance-associated substitutions that are selected by HCV NS5 A inhibitors because cerebrovascular adverse events are induced by some DAA drugs.

关键词： Resistance-associated substitutions Directacting antivirals Sustained viral response Hepatitis C

Successful surgical resection of ruptured cholangiolocellular carcinoma:A rare case of a primary hepatic tumor

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World Journal of Hepatology 2017年第16期9卷 752-756页

作者： Shota Akabane Takushiro Ban Shunsaku Kouriki Hiroyuki Tanemura Haruhiro nakazaki Masayuki Nakano Nobuaki Shinozaki Department of Surgery Shonan Fujisawa Tokushukai Hospital Department of Diagnostic Pathology Shonan Fujisawa Tokushukai Hospital

Spontaneous rupture is one of the most fatal complications of hepatic tumors such as hepatocellular carcinoma. In fact, many studies have shown that the in-hospital and 30-d mortality rates are as high as 25%-100%. Cholangiolocellular carcinoma(Co CC) is a rare primary hepatic tumor, usually small in size, that is thought to originate from the ductules and/or canals of Hering. Here, we present a case of spontaneous rupture of a Co CC that was successfully resected by radical surgery. Although Co CC is a rare primary hepatic tumor, it demonstrates certain specific clinical features, including a better prognosis than for other primary liver cancers, and thus should be distinguished from those other cancers. Moreover, Co CC can appear as a ruptured huge tumor, and when it does, radical hepatectomy can be an effective measure to achieve both absolute hemostasis and curability of tumor.

关键词： Hepatic tumor Rupture Cholangiolocellular carcinoma Resection Pathology

Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line

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Cellular & Molecular Immunology 2021年第6期18卷 1545-1561页

作者： Hidetaka Seo Hitomi Masuda Kenjiro Asagoshi Tomoaki Uchiki Shigehisa Kawata Goh Sasaki Takashi Yabuki Shunsuke Miyai Naoki Takahashi Shu-ichi Hashimoto Atsushi Sawada Aki Takaiwa Chika Koyama Kanako Tamai Kohei Kurosawa Ke-Yi Lin Kunihiro Ohta Yukoh nakazaki Department of Life Sciences Graduate School of Arts and SciencesThe University of TokyoTokyoJapan Research Laboratories Chiome Bioscience IncTokyoJapan

Monoclonal antibodies(mAbs)are widely utilized as therapeutic drugs for various diseases,such as cancer,autoimmune diseases,and infectious *** the avian-derived B cell line DT40,we previously developed an antibody display technology,namely,the ADLib system,which rapidly generates antigen-specific ***,we report the development of a human version of the ADLib system and showcase the streamlined generation and optimization of functional human *** libraries were first constructed by replacing endogenous immunoglobulin genes with designed human *** these libraries,clones producing full-length human IgGs against distinct antigens can be isolated,as exemplified by the selection of antagonistic *** advantage of avian biology,effective affinity maturation was achieved in a straightforward manner by seamless diversification of the parental clones into secondary libraries followed by single-cell sorting,quickly affording mAbs with improved affinities and ***,we demonstrate that the human ADLib system could serve as an integrative platform with unique diversity for rapid de novo generation and optimization of therapeutic or diagnostic antibody ***,our results suggest that libraries can be constructed by introducing exogenous genes into DT40 cells,indicating that the ADLib system has the potential to be applied for the rapid and effective directed evolution and optimization of proteins in various fields beyond biomedicine.

关键词： Immunoglobulin rearrangements homologous recombination antibody therapeutics antibody engineering drug discovery

High efficiency infrared PbS quantum dot solar cells toward the bottom subcell of tandem solar cells

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High efficiency infrared PbS quantum dot solar cells toward ...

Short-Wave Infrared PbS Colloidal Quantum Dot/ZnO Nanowire Solar Cells

第六届新型太阳能电池材料科学与技术学术研讨会

作者： Haibin Wang Takaya Kubo Jotara nakazaki Heroshi Segawa RCAST The University of Tokyo

Development of ultra-high efficiency low cost tandem solar cell is required for efficient utilization of solar energy. For the purpose, PbS colloidal quantum dots(CQDs) have been gaining much attention as promising constituent materials for solution processed-infrared solar cells because PbS QDs can absorb photon energy in a wider range of the solar spectrum. Among various CQD-based solar cells, PbS QD/ZnO-based depleted heterojunction solar cells showed a power conversion efficiency(PCE) over 12 % in 2018.1 But there is a limited number of literatures reporting on PbS QD based solar working in low photon energy region(< 1.0 eV). Our recent study revealed that PbS QD/ZnO nanowire(NW) solar cells were able to convert a wide range of solar energy to electricity. However, the free carrier absorption of the transparent conductive oxide(FTO: F-doped SnO) in infrared region cause a non-negligible energy loss of the incident solar energy to be absorbed by the PbS QD layer. In this presentation, we constructed infrared PbS QD/ZnO NW solar cells having the first exciton absorption peak at 1560 nm(0.8 eV) and successfully improved the spectral sensitivity in infrared region by employing highly infrared transparent 1% Ta-doped SnO(TTO) electrodes. The EQE reached its maximum value of 47% at 1560 nm. The integrated photo-current density obtained from the EQE spectrum over 38 mAcm for full solar spectrum(Fig.1). The solar cell installed with an 870 nm sharp-cut filter yielded a PCE of 2.02 %(J=14.8 mAcm;Vc=0.285 V;FF=47.9 %) under a filtered one-sun illumination. The PCE is the highest efficiency reported to date for solution processed solar cells working in the infrared region. Based on these results, we will discuss the potential of PbS QD/ZnO NW solar cells toward the bottom subcells of tandem solar cells.

关键词： Lead(Ⅱ) sulfide Colloidal quantum dots ZnO Nanowires Infrared

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Short-Wave Infrared PbS Colloidal Quantum Dot/ZnO Nanowire S...

Relationship between Pectic Substances and Strand Separation of Cooked Spaghetti Squash--Part 2. Changes in Firmness, Histological Structure and Pectic Substances during Soaking in Pectin Extractants

第五届新型太阳能电池学术研讨会

作者： Haibin Wang Takaya Kubo Jotara nakazaki Hiroshi Segawa Research Center for Advanced Science and Technology The University of Tokyo

Colloidal quantum dots(CQDs) give unique optical properties such as size dependent absorption,which makes the quantum dot promising candidate materials toward high efficiency solar *** most widely studied PbS CQD solar structures are based on depleted heterojunction that is formed by deposition of CQD layers on top of an electron-accepting layer such as ZnO or Ti *** enhance the performance of the solar cells,several strategies,which include new solar cell architectures and bandgap engineering,were reported.1 We focused on a solar cell composed of PbS QD/ZnO nanowire(NW) structures(Fig.1) with the aim of achieving efficient carrier transport and light absorption in the near-infrared region simultaneously.2,3 These PbS QD-based solar cells were also found to have high stability under continuous light soaking.4 We investigated the performance of PbS QD/ZnO NW solar cells using different PbS CQDs that absorb photons in a wide range of the solar spectrum.5 The solar cells were confirmed to convert a wide range of solar energy(0.35-2.0μm)(Fig.1).We found that the solar cells working in short-wave infrared(SWIR)region had a high open-circuit voltage(Voc) and the relatively low incident photon energy loss and small Voc deficit(Fig.2).These results indicate that solution-processed PbS CQD solar cells with ZnO nanowires are promising candidates for the middle and bottom subcells of multi-junction solar cells.5

关键词： Short-Wave Infrared PbS Quantum Dots ZnO Nanowire Solar Cells

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Journal of Food Science and Engineering 2014年第4期4卷 228-235页

作者： Kayoko Ishii Ai Teramoto Hiroko Kuwada Chihiro nakazaki Yuri Jibu Mayumi Tabuchi Michiko Fuchigami Department of Nutrition and Life Science Fukuyama University Fukuyama Hirosima-ken 729-0292 Japan Department of Health and Nutrition Kanto Gakuin University Yokohama Kanagawa-ken 236-8501 Japan Department of Nutritional Science Okayama Prefectural University Soja Okayama-ken 719-1197 Japan

The flesh of spaghetti squash separates into strands when cooked. The purpose of this paper is to investigate the cause of strand separation （during cooking） by soaking for 24 h at 35 ℃ in solutions with three kinds of pectin extractant. The changes in strand separation, firmness, histological structure and the pectin of flesh during soaking in 0.01 N HCI solution （pH 2.0）, 0.035 M ammonium oxalate solution （pH 4.0） or 2% sodium hexametaphosphate solution （pH 4.0） were investigated. When flesh was soaked in the HCI solution, the separation into strands and removal of calcium and magnesium were greater than that soaked in other pectin extractants. High methoxyl pectin was extracted by soaking in HC1 solution （pH 2.0） due to removal of polyvalent cations. This result shows that high methoxyl pectin glues strands together in the flesh of spaghetti squash. The shape of the cells which constituted strands was round; on the other hand, that of cells surrounded strands was elongated. When cooked in boiling water or soaked at pH 2.0, the shape of the former cells was maintained, but the latter cells, which contributed to adhesion between strands, broke down. Thus, the flesh separated into strands. When flesh was boiled for 15-30 min, pectin degraded and dissolved in the cooking solution; consequently, the flesh separated into strands and also the middle lamella of cell walls of strands separated. However, pectin remaining in strands maintained their crispness.

关键词： Spaghetti squash pectin texture histological structure strand separation soaking pectin extractant.

Recent progress in perovskite solar cells:from device to commercialization

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Science China Chemistry 2022年第12期65卷 2369-2416页

作者： Xinhui Luo Xuesong Lin Feng Gao Yang Zhao Xiaodong Li Liqing Zhan Zexiong Qiu Jin Wang Cong Chen Lei Meng Xiaofeng Gao Yu Zhang Zijian Huang Rundong Fan Huifen Liu Yanrun Chen Xiaoxue Ren Jiahong Tang Chun-Hao Chen Dong Yang Yongguang Tu Xiao Liu Dongxue Liu Qing Zhao Jingbi You Junfeng Fang Yongzhen Wu Hongwei Han Xiaodan Zhang Dewei Zhao Fuzhi Huang Huanping Zhou Yongbo Yuan Qi Chen Zhaokui Wang Shengzhong(Frank)Liu Rui Zhu Jotaro nakazaki Yongfang Li Liyuan Han State Key Laboratory of Metal Matrix Composites School of Material Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China State Key Lab for Mesoscopic Physics and Frontiers Science Center for Nano-optoelectronics School of PhysicsPeking UniversityBeijing 100871China Key Laboratory of Semiconductor Materials Science Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China School of Physics and Electronic Science Engineering Research Center of Nanophotonics&Advanced InstrumentMinistry of EducationEast China Normal UniversityShanghai 200241China Key Laboratory for Advanced Materials and Institute of Fine Chemicals School of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China Institute of Photoelectronic Thin Film Devices and Technology Renewable Energy Conversion and Storage CenterSolar Energy Research CenterNankai UniversityTianjin 300350China College of Materials Science and Engineering&Engineering Research Center of Alternative Energy Materials&Devices Ministry of EducationSichuan UniversityChengdu 610065China Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic SolidsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China Beijing Key Laboratory for Theory and Technology of Advanced Battery Materials Key Laboratory of Polymer Chemistry and Physics of Ministry of EducationSchool of Materials Science and EngineeringPeking UniversityBeijing 100871China School of Physics and Electronics Hunan Key Laboratory of Nanophotonics and DevicesCentral South UniversityChangsha 410083China Experimental Center for Advanced Materials School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Jia

Perovskite solar cells(PSCs) are undergoing rapid development and the power conversion efficiency reaches 25.7% which attracts increasing attention on their commercialization *** this review,we summarized the recent progress of PSCs based on device structures,perovskite-based tandem cells,large-area modules,stability,applications and ***,the challenges and perspectives are discussed,aiming at providing a thrust for the commercialization of PSCs in the near future.

关键词： perovskite solar cells device engineering stability application