The purpose of the current investigations is to solve the nonlinear dynamics based on the nervous stomach model(nSM)using the supervised neural networks(Snns)along with the novel features of Levenberg-Marquardt backpr...
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The purpose of the current investigations is to solve the nonlinear dynamics based on the nervous stomach model(nSM)using the supervised neural networks(Snns)along with the novel features of Levenberg-Marquardt backpropagation technique(LMBT),i.e.,*** Snns-LMBT is implemented with three different types of sample data,authentication,testing and *** ratios for these statistics to solve three different variants of the nonlinear dynamics of the nSM are designated 75%for training,15%for validation and 10%for testing,*** the numerical measures of the nonlinear dynamics of the nSM,the Runge-Kutta scheme is implemented to form the reference *** attained numerical form of the nonlinear dynamics of the nSM through the Snns-LMBT is implemented in the reduction of the mean square error(MSE).For the exactness,competence,reliability and efficiency of the proposed Snns-LMBT,the numerical actions are capable using the proportional arrangements through the features of the MSE results,error histograms(EHs),regression and correlation.
A simple and rapid liquid chromatography-tandem mass spectrometric(LC-MS/MS) assay method has been developed and fully validated for simultaneous quantification of pioglitazone and candesartan in human *** was used as...
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A simple and rapid liquid chromatography-tandem mass spectrometric(LC-MS/MS) assay method has been developed and fully validated for simultaneous quantification of pioglitazone and candesartan in human *** was used as an internal *** analytes were extracted from human plasma samples by solid-phase extraction technique using a Strata-X 33 mm polymeric *** reconstituted samples were chromatographed on a C18 column by using a 80:20(v/v) mixture of acetonitrile and 0.1% formic acid as the mobile phase at a flow rate of 0.8 mL/*** calibration curves obtained were linear(rZ0.99) over the concentration range of 15-3000 ng/mL for pioglitazone and 5-608 ng/mL for *** results of the intra-and inter-day precision and accuracy studies were well within the acceptable limits.A run time of 2.7 min for each sample made it possible to analyze more than 300 plasma samples per *** proposed method was found to be applicable to clinical studies.
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