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Finite element analysis of overlay incorporating stress absorbing membrane interlayers against reflective cracking

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Journal of Modern Transportation 2014年第2期22卷 104-111页

作者： O.M.Ogundipe n.H.Thom A.C.Collop Civil Engineering Department Ekiti State University nTEC University of Nottingham Faculty of Technology De-Montfort University

A wheel tracking test was modelled to gain better understanding of the deflection and stress-strain distribution in an overlaid cracked pavements with and without membrane interlayer （SAMI）. For this purpose, commercial finite element software Abaqus 6.7-1 was used. Two different models were considered, one incorporating stress absorbing membrane interlayers （SAMIs） and the other without SAMI. In the study, full bond condition was assumed for the boundaries between the layers, and a linear elastic model was used for the analysis. The results show that introduction of SAMI caused greater deflection of the pavement. It is found that although with SAMIs, low stiffness is required, a very low stiffness may yield undesirable results. The results show that the introduction of SAMIs results in high strain concentration around the crack region, whilst the strain in the overlay is smaller than the values predicted in the models without SAMIs.

关键词： Overlay Interlayers Crack - Strain Stress

Deep Residual network Based on Image Priors for Single Image Super Resolution in FFA Images

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Computer Modeling in Engineering & Sciences 2020年第10期125卷 125-143页

作者： G.R.Hemalakshmi D.Santhi V.R.S.Mani A.Geetha n.B.Prakash national Engineering College Kovilpatti628503India

Diabetic retinopathy,aged macular degeneration,glaucoma *** widely prevalent ocular pathologies which are irreversible at advanced *** learning based automated detection of these pathologies facilitate timely clinical interventions,preventing adverse *** screen these pathologies with fundus Fluorescein Angiography Images(FFA)which capture retinal components featuring diverse morphologies such as retinal vasculature,macula,optical disk ***,these images have low resolutions,hindering the accurate detection of ocular *** of high resolution images from these images,by super resolution approaches expedites the diagnosis of pathologies with better *** paper presents a deep learning network for Single Image Super Resolution(SISR)of fundus fluorescein angiography images,modeled on residual learning,gridded interpolation and Swish activation *** image prior for this network is constructed by gridded interpolation which provides better image fidelity compared to other *** of the performance of this network and comparative analysis with benchmark architectures,on a standard dataset shows that the proposed network is superior with respect to performance metrics and computational time.

关键词： SISR FFA residual network gridded interpolation swish function

Portal vein ligation accelerates tumor growth in ligated,but not contralateral lobes

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World Journal of Gastroenterology 2010年第30期16卷 3816-3826页

作者： nozomu Sakai Callisia n Clarke Rebecca Schuster John Blanchard Amit D Tevar Michael J Edwards Alex B Lentsch Department of Surgery University of Cincinnati231 Albert Sabin WayCincinnatiOH 45267-0558United States

AIM: To investigate the mechanisms of liver growth and atrophy after portal vein ligation (PVL) and its effects on tumor growth. METHODS: Mice were subjected to PVL, partial hepatectomy, or sham surgery. The morphological alterations, activation of transcription factors, and expression of cytokines and growth factors involved in liver regeneration were evaluated. In a separate set of experiments, murine colorectal carcinoma cells were injected via the portal vein and the effect of each operation on liver tumor growth was studied. RESULTS: Liver regeneration after PVL and partial hepatectomy were very similar. In ligated lobes, various cytokines, transcription factors and regulatory factors were signifi cantly upregulated compared to nonligated lobes after PVL. Atrophy in ligated lobes was a result of early necrosis followed by later apoptosis. Tumor growth was signifi cantly accelerated in ligated compared to non-ligated ***: Tumor growth was accelerated in ligated liver lobes and appeared to be a result of increased growth factor expression.

关键词： Portal vein ligation Tumor growth Growth factor Atrophy Apoptosis

Ozone during Stratospheric Warmings at Uccle

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Advances in Atmospheric Sciences 1991年第2期8卷 251-255页

作者： V. n. R. Mukku C. S. Bhosale Indian Institute of Tropical Meteorology Pune-411008 IndiaIndian Institute of Tropical Meteorology Pune-411008 India

The day-to-day variations in ozone content at Uccle (51°n) during some stratospheric warming events are examined. In particular, the attention is focused on the timing of commencement of ozone enhancement prior to peak day of warming and on the relationship in the ozone content between the upper and lower stratosphere. These two features are compared with the predictions of ozone transport models. There seems to be an agreement between model predictions and observed features in some cases.

关键词： Ozone during Stratospheric Warmings at Uccle

ZnO/PAnI nanoflake arrays sensor for ultra-low concentration and rapid detection of nO_(2)at room temperature

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Rare Metals 2023年第2期42卷 536-544页

作者： Qiu-Yue Zheng Meng Yang Xin Dong Xian-Fa Zhang Xiao-Li Cheng Li-Hua Huo Zoltán Major Ying-Ming Xu Key Laboratory of Functional Inorganic Material Chemistry Ministry of EducationSchool of Chemistry and Materials ScienceHeilongjiang UniversityHarbin150080China Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education School of Chemistryand State Key Laboratory of Optoelectronic Materials and TechnologiesSun Yat-Senen UniversityGuangzhou510275China Institute of Polymer Product Engineering Johannes Kepler University Linz124040LinzAustria

With the development of environmental monitoring,it is urgent to establish nO_(2)sensor with good sensing *** with the traditional nO_(2)sensors made of metal oxides,nO_(2)sensors made of n-p heterostructure nanocomposites have good sensing performance in detection limit and operating *** nanoflake arrays with polyaniline film grown on the surface were prepared on ceramic tubes by hydrothermal and vapor diffusion *** gas-phase diffusion method can control the heterostructure by adjusting the diffusion *** room temperature(25℃),the construction of rich n-p heterogeneous interface enables the sensor prepared by the nanocomposite to respond to nO_(2),showing the sensing performance with the response value of 28.00 to10.00×10^(-6)nO_(2);the detection limit improved to0.01×10^(-6)and the recovery time of 18 *** this work,the sensing mechanism of nO_(2)at heterogeneous interface is analyzed,which provides a promising material for the detection of low concentration nO_(2)at room temperature.

关键词： ZnO/polyaniline(PAnI)nanoflake arrays n-p heterostructure Ultra-low concentration nO_(2)gas sensor Rapid detection

Informative ISSR Markers Help Identify Genetically Distinct Accessions of Oryza rufipogon in Yield Improvement

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Rice science 2016年第5期23卷 225-241页

作者： G.HARITHA T.SUDHAKAR D.CHAnDRA T.RAM B.DIVYA n.SARLA ICAR Indian Institute of Rice Research

Inter simple sequence repeat（ISSR） polymorphism was used to determine genetic diversity and phylogenetic relationships in 90 genotypes of wild and cultivated species of Oryza from different geographical regions of the world. In all the 17 primers used in ISSR-PCR, a total of 11 464 bands were amplified at 253 band positions/loci. The primer UBC-809 amplified the maximum bands（1 059） at 21 band positions. UBC-810 and UBC-835 amplified the minimum of 391 bands each at 7 and 14 band positions, respectively. The mean polymorphism information content ranged from 0.44 to 0.84 and resolving power ranged from 8.69 to 23.53. Un-weighted pair group method with arithmetic mean dendrogram and population structure based on the 17 primers separated all genotypes into 4 major clusters with a genetic similarity of 53%–100%. The first two clusters consisted of 30 O. rufipogon accessions each. In the third cluster, O. nivara and O. longistaminata grouped as one sub-cluster and all other O. nivara accessions and cultivars grouped as another sub-cluster. The fourth cluster had only five O. rufipogon accessions which can be a source of new genes. Four sub-populations were identified within O. rufipogon and two sub-populations within O. nivara at K = 7. A subset of six primers with high resolving power values were the most informative and grouped all genotypes almost similarly as the 17 primers did. Use of these six highly informative primers in ISSR-PCR is a cost effective and robust method for assessing genetic diversity in large germplasm collections of wild rice species.

关键词： Oryza wild species genetic diversity population structure inter simple sequence repeat

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Guest Editorial

Digital Communications and networks 2022年第6期8卷 865-867页

作者： Honghao Gao Ramon J.Duran Barroso Zhiyuan Tan School of Computer Engineering and Science Shanghai UniversityChina Universidad de Valladolid Spain School of Computing Edinburgh Napier UniversityUK

Special issue on Collaborative computing to information fusion for5GIoTsocialdata With the development of 5G IoT technology,a large amount of social data is generated every *** to handle these social data has become a critical *** Fusion with Collaborative Computing aims to help academia and industry understand data,information and ***,in this special issue,we selected the following highquality papers from open submissions.A summary is outlined below.

关键词： handle problem IoT

Adsorption and Uptake of Cadmium by Azolla pinnata:Kinetics of Inhibition by Cations

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Biomedical and Environmental Sciences 1995年第2期8卷 149-157页

作者： J.P.GAUR n.nORAHO LaboratoryofAlgalBiology CentreofAdvancedStudyinBotanyBanarasHinduUniversityVaranasi221005India Bo

A. pinnata showed a remarkable ability of taking up Cd from the external medium. Of the total Cd taken up by the test plant, surface adsorption was about 90%. Cd adsorption did not occur at a constant rate, however, an equilibrium was reached in 2 h. The uptake of Cd occurred at a constant rate. Test cations, including heavy metals (Ca, Mg, K, na,ni, Fe, Cu and Zn), inhibited adsorption as well as uptake of Cd. Cd adsorption was competitively inhibited by Cu, Fe and Zn, whereas Ca, Mg, K, na and ni caused non-competitive inhibition. Similarly, Cd uptake was competitively (Ca, Mg, Fe) or non-competitively (na, K, ni, Zn) inhibited by cations. Inhibition of Cd uptake by Cu was not wholly competitive

关键词： Adsorption and Uptake of Cadmium by Azolla pinnata

In Silico Pipeline to Identify Tumor‑Specific Antigens for Cancer Immunotherapy Using Exome Sequencing Data

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Phenomics 2023年第2期3卷 130-137页

作者： Diego Morazán‑Fernández Javier Mora Jose Arturo Molina‑Mora Caja Costarricense de Seguro Social San José10104Costa Rica Centro de Investigación de Enfermedades Tropicales Centro de Investigación en Cirugía y Cáncerand Facultad de MicrobiologíaUniversidad de Costa RicaSan José2060Costa Rica

Tumor-specific antigens or neoantigens are peptides that are expressed only in cancer cells and not in healthy *** of these molecules can induce an immune response,and therefore,their use in immunotherapeutic strategies based on cancer vaccines has been extensively *** based on these approaches have been triggered by the current high-throughput DnA sequencing ***,there is no universal nor straightforward bioinformatic protocol to discover neoan-tigens using DnA sequencing ***,we propose a bioinformatic protocol to detect tumor-specific antigens associated with single nucleotide variants(SnVs)or“mutations”in tumoral *** this purpose,we used publicly available data to build our model,including exome sequencing data from colorectal cancer and healthy cells obtained from a single case,as well as frequent human leukocyte antigen(HLA)class I alleles in a specific *** data from Costa Rican Central Valley population was selected as an *** strategy included three main steps:(1)pre-processing of sequencing data;(2)variant calling analysis to detect tumor-specific SnVs in comparison with healthy tissue;and(3)prediction and characterization of peptides(protein fragments,the tumor-specific antigens)derived from the variants,in the context of their affinity with frequent alleles of the selected *** our model data,we found 28 non-silent SnVs,present in 17 genes in chromosome *** protocol yielded 23 strong binders peptides derived from the SnVs for frequent HLA class I alleles for the Costa Rican *** the analyses were performed as an example to implement the pipeline,to our knowledge,this is the first study of an in silico cancer vaccine using DnA sequencing data in the context of the HLA *** is concluded that the standardized protocol was not only able to identify neoantigens in a specific but also provides a complete pipeline for the eventual design of cancer vaccines using

关键词： neopeptide Colorectal cancer Cancer vaccine neoantigens Human leukocyte antigen Costa Rica