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Gold nanoshells： Contrast agents for cell imaging by cardiovascular optical coherence tomography

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nano research 2018年第2期11卷 676-685页

作者： Jie Hu Francisco Sanz-rodríguez Fernando rivero Emma Martín.rodríguez río Aguilar Torres Dirk H. Ortgies José García Solé Fernando Alfonso Daniel Jaque Fluorescence Imaging Group Departamento de Física de Materiales Instituto Nicolás Cabrera Facultad de Ciencias Universidad Autónoma de Madrid Madrid Spain Instituto ramón y Cajal de Investigación Sanitaria Hospital ramón y Cajal Madrid Spain Departamento de Biología Universidad Autónoma de Madrid Madrid Spain Cardiology Department Hospital Universitario de la Princesa IIS-IP Universidad Autónoma de Madrid Madrid Spain

Optical coherence tomography （OCT） has gained considerable attention in interventional cardiovascular medicine and is currently used in clinical settings to assess atherosclerotic lesions and to optimize stent placement. Artery imaging at the cellular level constitutes the first step towards cardiovascular molecular imaging, which represents a major advance in the development of personalized noninvasive therapies. In this work we demonstrate that cardiovascular OCT can be used to detect individual cells suspended in biocompatible fluids. Importantly, the combination of this catheter-based clinical technique with gold nanoshells （GnSs） as intracellular contrast agents led to a substantial enhancement in the backscattered signal produced by individual cells. This cellular contrast enhancement was attributed to the large backscattering cross-section of GnSs at the OCT laser wavelength （1,300 nm）. A simple intensity analysis of OCT cross-sectional images of suspended cells makes it possible to identify the sub-population of living cells that successfully incorporated GnSs. The generalizability of this method was demonstrated using two different cell lines （HeLa and Jurkat cells）. This work provides novel insights into cardiovascular molecular imaging using specifically modified GnSs.

关键词： optical coherencetomography (OCT)intravascular imaging gold nanoparticles three-dimensional (3D)imaging

Maschke Type Theorems for Weak Hopf Quasigroups

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Algebra Colloquium 2020年第2期27卷 213-230页

作者： J.n.Alonso Alvarez J.M.Fernández Vilaboa r.González rodríguez Departamento de Matematicas Vniversidade de Vigo Campus Universitario Lagoas-MarcosendeE-36280 VigoSpain Departamento de Matematicas Universidade de Santiago de Compostela E-15771 Santiago de CompostelaSpain Departamento de Matematica Aplicada II Universidade de Vigo Campus Universitario Lagoas-MarcosendeE-36310 VigoSpain

In this paper we give necessary and sufficient conditions for a comodule magma over a weak Hopf quasigroup to have a total integral,thus extending the theories developed in the Hopf algebra,weak Hopf algebra and non-associative Hopf algebra *** this result we also deduce a version of Maschke’s theorems for right(H,B)-Hopf triples associated to a weak Hopf quasigroup H and a right H-comodule magma B.

关键词： (weak)Hopf algebra (weak)Hopf quasigroup integral Maschke theorem

Mercury removal using ground and calcined mussel shell

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Journal of Environmental Sciences 2013年第12期25卷 2476-2486页

作者： Susana Pea-rodríguez Alipio Bermúdez-Couso Juan Carlos nóvoa-Muoz Manuel Arias-Estvez María J.Fernndez-Sanjurjo Esperanza lvarez-rodríguez Avelino núez-Delgado rea de Edafoloxía e Qu' mica Agr' cola. Departamento de Bioloxía Vexetal e Ciencia do Solo. Univ. Vigo. Facultade de Ciencias Ourense Departamento de Edafoloxía e Química Agrícola. Univ. Santiago de Compostela. Escola Politcnica Superior campus univ. s/n

We determined mercury retention on calcined and ground mussel shell, in presence and absence of phosphate, using batch and stirred flow chamber experiments. In batch experiments the calcined shell exhibited higher Hg adsorption, with good fitting to Freundlich equation （r^2： 0.925-0.978）; the presence of phosphate increased Hg adsorption; mercury desorption was 13% or lower, diminishing up to 2% under the presence of phosphates. In stirred flow chamber experiments calcined shell retained more Hg than ground shells （6300 vs. 4000-5200 μmol/kg）; Hg retention increased an additional 40% on calcined shell and up to an additional 70% on ground shells when phosphates were present; mercury desorption was quite similar in all shell types （20%-34%）, increasing up to 49%-60% in ground shells when phosphates were present. The higher Hg adsorption on calcined shell would be related to its calcite and dolomite concentrations; mercury-phosphate interactions would cause the increase in Hg retention when phosphates are present. Data on Hg desorption suggest that Hg retention was not easily reversible after batch experiments, increasing in the stirred flow chamber due to convective flow. Calcined and ground mussel shells could be recycled removing Hg from water, with the presence of phosphates in solution improving efficacy.

关键词： adsorption desorption heavy metals pollution mercury mollusc shell

Soil Conservation Measures in rainfed Olive Orchards in South-Eastern Spain: Impacts of Plant Strips on Soil Water Dynamics

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Pedosphere 2009年第4期19卷 453-464页

作者： V. H. DUrn ZUAZO C. r. rodríguez PLEguezUELO L. ArrOYO PAnADErO A. MArTínEZ rAYA J. r. FrAnCIA MArTínEZ B. CrCELES rodríguez Instituto de Investigación y Formación Agraria y Pesquera IFAPA Centro Camino de Purchil

Sloping and mountainous olive production systems are widespread, occupying large parts of the Mediterranean landscape prone to water erosion. Soil erosion, runoff, and soil water content patterns over a three-year period were monitored in erosion plots on a mountainside with rainfed olive （Olea europaea cv. Picual） trees under： 1） non-tillage with barley strips of 4 m width （BS）; 2） non-tillage with native vegetation strips of 4 m width （nVS）; and 3） non-tillage without plant strips （nT）. The erosion plots, located in Lanjaron （Granada, south-eastern Spain）, on a 30% slope, were 192 m2 in area. For assessing soil water dynamics in real-time and near-continuous soil water content measurements, multisensor capacitance probes were installed in the middle of plant strips and beneath the olive tree at five soil depths （10, 20, 30, 50, and 100 cm）. The highest erosion and runoff rates were measured under nT, with a mean of 17.3 Mg ha-1 year-1 and 140.0 mm year-1, respectively, over the entire study period. The BS and nVS with respect to the nT reduced erosion by 71% and 59% and runoff by 95% and 94%, respectively. In general, greater available soil water content was found under BS than nVS and nT, especially beneath the olive tree canopies. These results supported the recommendation of non-tillage with barley strips in order to reduce erosion and to preserve soil water for trees in traditional mountainous olive-producing areas, where orchards cover vast tracts of land.

关键词： farming systems native plants runoff soil erosion

Climate,female traits and population features as drivers of breeding timing in Mediterranean red deer populations

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Integrative Zoology 2017年第5期12卷 396-408页

作者： Marta PELÁEZ Alfonso SAn MIGUEL Carlos rodrÍguez-VIGAL ramón PErEA Department of natural Systems and resources Technical University of MadridMadridSpain national Parks Autonomous Agency MadridSpain Department of Biology Stanford UniversityStanfordCaliforniaUSA

Understanding the factors that lead to variation in the timing of breeding in widespread species such as red deer(Cervus elaphus)is crucial to predict possible responses of wild populations to different climate ***,we sought to further understand the causes of inter-annual variation in the reproduction timing of female deer in Mediterranean *** integrative approach was used to identify the relative importance of individual,population and climate traits in the date of conception of free-ranging deer,based on a dataset of 829 hinds culled during 12 *** found that a population trait,density,was the most important factor explaining the variation in conception dates,with greater densities causing later conception *** mass was the second in importance,with heavier females conceiving earlier than lighter *** equally important was the spring real bioclimatic index,a measure of plant productivity,causing later conception dates in the least productive springs(drier and hotter).Another climatic component,the end of summer drought,showed that the sooner the autumn arrives(greater rainfalls and cooler temperatures)the earlier the conception ***,age class was found to be a minor factor in determining conception *** older females(≥10 years old)conceived significantly later,suggesting reproductive *** study highlights not only the importance of population and individual traits but also the influence of climatic parameters on the deer reproductive cycle in Mediterranean environments,giving valuable insight into how reproductive phenology may respond to seasonality and global climate changes.

关键词： density-dependence mating short-day breeder summer drought ungulates

Changes in microhabitat, but not allelopathy, affect plant establishment after Acacia dealbata invasion

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Journal of Plant Ecology 2017年第4期10卷 610-617页

作者： Paula Lorenzo Jonatan.rodríguez Luís González Susana rodríguez-Echeverría Centre for Functional Ecology(CFE) Department of Life SciencesUniversity of CoimbraCalçada Martim de Freitas3000-456 CoimbraPortugal Facultade de Bioloxía Departamento de Bioloxía Vexetal e Ciencia do SoloUniversidade de VigoAs Lagoas-Marcosende s/n36310PontevedraSpain

Aims The tree legume Acacia dealbata Link is an aggressive Australian invader that severely affects abiotic and biotic compartments of eco-systems *** invasive species outcompetes native plant communities through direct competition,changes in microhabitat and soil properties under the canopy and the release of allelopathic ***,these effects are usually studied separately and under controlled *** objective of this study was to evaluate the combined effect of these modifications exerted by *** on the establishment of native and invasive species in the *** A full factorial experiment was performed in order to test the com-bined effect of microhabitat,soil type and allelopathy on the establish-ment of the invasive *** and three native species in the field(north-West Spain).We sowed seeds of native or invasive species in pots with different soil type(soil collected under *** or Pinus pinaster),allelopathy status(soil treated or untreated with activated car-bon)and microhabitat(under the canopy of *** or ***).The number and total biomass of established plants were evaluated after 8 *** abiotic properties were determined in all *** Findings The establishment of native and invasive species was signifi-cantly affected by the microhabitat,with a higher number of seedlings under the native forest(***).The establishment of *** seedlings was also significantly promoted by its own soil.A negligible effect of allelopathy was detected on the establishment and growth of both invasive and native *** conclude that(i)the main factor affecting seedling establish-ment was microhabitat rather than changes in soil properties or allelopathy,(ii)soil modifications by *** promote the establishment of its own seedlings,contributing to the progress of invasion and(iii)allelochemicals released by *** do not seem to play a key role for the establishment of native

关键词： plant invasion microhabitat soil changes allelopathy plant establishment

Diabetic peripheral neuropathy and neuromodulation techniques:a systematic review of progress and prospects

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neural regeneration research 2025年第8期20卷 2218-2230页

作者： rahul Mittal Keelin McKenna Grant Keith Evan McKenna Joana r.n.Lemos Jeenu Mittal Khemraj Hirani Diabetes research Institute University of Miami Miller School of MedicineMiamiFLUSA Department of Otolaryngology University of Miami Miller School of MedicineMiamiFLUSA Herbert Wertheim College of Medicine Florida International UniversityMiamiFLUSA School of Medicine and Public Health University of WisconsinMadisonWIUSA

neuromodulation for diabetic peripheral neuropathy represents a significant area of interest in the management of chronic pain associated with this *** peripheral neuropathy,a common complication of diabetes,is characterized by nerve damage due to high blood sugar levels that lead to symptoms,such as pain,tingling,and numbness,primarily in the hands and *** aim of this systematic review was to evaluate the efficacy of neuromodulatory techniques as potential therapeutic interventions for patients with diabetic peripheral neuropathy,while also examining recent developments in this *** investigation encompassed an array of neuromodulation methods,including frequency rhythmic electrical modulated systems,dorsal root ganglion stimulation,and spinal cord *** systematic review suggests that neuromodulatory techniques may be useful in the treatment of diabetic peripheral *** the advantages of these treatments will enable physicians and other healthcare providers to offer additional options for patients with symptoms refractory to standard pharmacologic *** these efforts,we may improve quality of life and increase functional capacity in patients suffering from complications related to diabetic neuropathy.

关键词： diabetes mellitus diabetic peripheral neuropathy neuromodulation neurostimulation therapy non-pharmacological treatment pain management

A Maschke Type Theorem for Weak Hopf Algebras

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Acta Mathematica Sinica,English Series 2008年第12期24卷 2065-2080页

作者： J.n.ALOnSOLVArEZ J.M.FErnnDEZVILABOA r.GOnZLEZrodríguez A.B.rodríguezrAPOSO Departamento de Matemáticas Universidad de Vigo. Lagoas-Marcosende Vigo. E-36200 Spain Departamento de lxebra. Universidad de Santiago de Compostela Santiago de Compostela. E-15771 Spain Departamento de Matemdtica Aplicada Ⅱ. Universidad de Vigo. Lagoas-Marcosende Vigo. E-36310 Spain Departamento delxebra Universidad de Santiago de CompostelaSantiago de Compostela E-15771 Spain

In this paper, we give a necessary and sufficient condition for a comodule algebra over a weak Hopf algebra to have a total integral, thus extending the classical theory developed by Doi in the Hopf algebra setting. Also, from these results, we deduce a version of Maschke＇s Theorem for （H, B）-Hopf modules associated with a weak Hopf algebra H and a right H-comodule algebra B.

关键词： Monoidal category weak Hopf algebra Hopf modules Maschke Theorem

Deadly oasis:recurrent annihilation of Cretaceous desert bryophyte colonies;the role of solar,climate and lithospheric forcing

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Geoscience Frontiers 2021年第1期12卷 1-12页

作者： Juan Pedro rodríguez-Lópeza Eduardo Barrón Daniel Peyrot Gary B.Hughes Department of Geology.Faculty of Science.United Arab Emirates University.50009.Al Ain Abu DhabiUnited Arab Emirates Instituto Geológico y Minero de Espana(IGME) Ríos Rosas 23E-28003MadridSpain School of Earth and Environment University of Western Australia.6101CrawleyWestern AustraliaAustralia Centre for Energy Geosciences University of Western Australia.6101CrawleyWestern AustraliaAustralia Physics Department University of CaliforniaSanta BarbaraCA93106USA

Many oases(wet interdunes)are sedimentary systems characterized by high-frequency water-level oscillations,marked changes in salinity and intense biological activity at their *** are considered to be one of the most challenging environments on Earth for ecosystem *** dynamic,depositional settings are usually unfavourable for fossilization and subsequent preservation of vegetal *** paper describes bryophyte(liverwort)assemblages occurring in three successive horizons interpreted to represent(i)recurrent early successional phases of biological soil crust colonization of wet interdune margins or(ii)exceptional preservation of floating or riparian liverworts in oasis pond waters associated with a progressive fall of the interdune water *** record of in situ colonization surfaces characterized by delicate(***-free)three-dimensional structures represents an exceptional type of preservation herein associated with a rapid variation in phreatic interdune water level and the subsequent establishment of anoxic and reducing *** occurrence of exceptionally preserved liverwort colonies coincides with the sedimentary record of,at least,three seismite levels in the *** gathered from the site suggests that the water table of the oasis was controlled by a combination of(i)a positive creation of accommodation space due to subsidence associated with movement on syn-sedimentary extensional faults,and(ii)the rise and fall of the oasis water table controlled by the oscillations of the groundwater system due to orbital changes which appear to drive the variability of the climate *** groundwater levels flooded the oasis soil crusts and lead to the exceptional recurrent preservation of liverwort colonies at the oasis ***,considering the hypothesis of floating or riparian liverworts in the oasis pond waters,the fall in the level of the oasis water table placed the floating liverworts in contact with the

关键词： Oasis Cretaceous Liverworts Colonies Extensional tectonics Solar cyclicity